WO2014110071A3 - Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation - Google Patents

Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation Download PDF

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Publication number
WO2014110071A3
WO2014110071A3 PCT/US2014/010589 US2014010589W WO2014110071A3 WO 2014110071 A3 WO2014110071 A3 WO 2014110071A3 US 2014010589 W US2014010589 W US 2014010589W WO 2014110071 A3 WO2014110071 A3 WO 2014110071A3
Authority
WO
WIPO (PCT)
Prior art keywords
atrial fibrillation
vagus nerve
avert
treat
stimulation devices
Prior art date
Application number
PCT/US2014/010589
Other languages
French (fr)
Other versions
WO2014110071A2 (en
Inventor
Bruce J. Simon
Joseph P. Errico
John T. RAFFLE
Original Assignee
ElectroCore, LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/736,096 external-priority patent/US9126050B2/en
Application filed by ElectroCore, LLC filed Critical ElectroCore, LLC
Publication of WO2014110071A2 publication Critical patent/WO2014110071A2/en
Publication of WO2014110071A3 publication Critical patent/WO2014110071A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/395—Heart defibrillators for treating atrial fibrillation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36031—Control systems using physiological parameters for adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/37—Monitoring; Protecting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Energy is transmitted noninvasively to a patient using electrode-based stimulation devices or magnetic stimulation devices that are designed to non-invasively stimulate nerves selectively. The devices produce impulses that are used to treat atrial fibrillation, by stimulating a vagus nerve of a patient. The devices are also used to forecast the imminent onset of atrial fibrillation and then avert it by stimulating a vagus nerve.
PCT/US2014/010589 2013-01-08 2014-01-08 Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation WO2014110071A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/736,096 2013-01-08
US13/736,096 US9126050B2 (en) 2009-03-20 2013-01-08 Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation

Publications (2)

Publication Number Publication Date
WO2014110071A2 WO2014110071A2 (en) 2014-07-17
WO2014110071A3 true WO2014110071A3 (en) 2015-02-26

Family

ID=51167497

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/010589 WO2014110071A2 (en) 2013-01-08 2014-01-08 Non-invasive vagus nerve stimulation devices and methods to treat or avert atrial fibrillation

Country Status (1)

Country Link
WO (1) WO2014110071A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730809A (en) * 2021-10-09 2021-12-03 西安科悦医疗股份有限公司 Non-invasive vagus nerve combined sacral nerve stimulation device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040138721A1 (en) * 1999-04-30 2004-07-15 Medtronic, Inc. Vagal nerve stimulation techniques for treatment of epileptic seizures
US20120184801A1 (en) * 2009-03-20 2012-07-19 ElectroCore, LLC Nerve stimulation methods for averting imminent onset or episode of a disease
US20130131753A1 (en) * 2009-03-20 2013-05-23 ElectroCore, LLC. Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders
US20130238050A1 (en) * 2009-03-20 2013-09-12 ElectroCore, LLC. Non-invasive vagal nerve stimulation to treat disorders

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040138721A1 (en) * 1999-04-30 2004-07-15 Medtronic, Inc. Vagal nerve stimulation techniques for treatment of epileptic seizures
US20120184801A1 (en) * 2009-03-20 2012-07-19 ElectroCore, LLC Nerve stimulation methods for averting imminent onset or episode of a disease
US20130131753A1 (en) * 2009-03-20 2013-05-23 ElectroCore, LLC. Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders
US20130238050A1 (en) * 2009-03-20 2013-09-12 ElectroCore, LLC. Non-invasive vagal nerve stimulation to treat disorders

Also Published As

Publication number Publication date
WO2014110071A2 (en) 2014-07-17

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