WO2014101466A1 - Jauge de pression artérielle - Google Patents

Jauge de pression artérielle Download PDF

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Publication number
WO2014101466A1
WO2014101466A1 PCT/CN2013/083099 CN2013083099W WO2014101466A1 WO 2014101466 A1 WO2014101466 A1 WO 2014101466A1 CN 2013083099 W CN2013083099 W CN 2013083099W WO 2014101466 A1 WO2014101466 A1 WO 2014101466A1
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WO
WIPO (PCT)
Prior art keywords
pulse wave
blood pressure
state
sensing device
signal
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PCT/CN2013/083099
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English (en)
Chinese (zh)
Inventor
明利强
刘方
孙业军
Original Assignee
深圳迈瑞生物医疗电子股份有限公司
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Publication of WO2014101466A1 publication Critical patent/WO2014101466A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1118—Determining activity level
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7296—Specific aspects of physiological measurement analysis for compensation of signal variation due to stress unintentionally induced in the patient, e.g. due to the stress of the medical environment or examination

Definitions

  • the present application relates to the field of medical devices, and in particular to a blood pressure measuring instrument.
  • non-invasive blood pressure measurements are typically performed using cuff punching and oscillometric methods to detect non-invasive blood pressure. That is, a pulse wave sensing device is installed inside the sleeve, and the sensed pulse wave is transmitted through the airway tube to the main control portion of the non-invasive blood pressure measuring device. The main control part is converted into a digital signal by signal acquisition, and then the blood pressure value is calculated using a professional algorithm.
  • the detection of the posture and movement of the subject's arm is ignored.
  • blood pressure measurement has a great relationship with the posture and movement of the subject's arm.
  • the measured blood pressure accuracy and reference value are different.
  • the blood pressure value in the sleep state of the subject is lower than that in the awake state, and this can be judged by whether the posture of the arm is flat.
  • the blood pressure value is often inaccurate or unreliable due to interference caused by exercise.
  • the traditional sphygmomanometer does not consider these scenarios, especially in the case of home and long-term monitoring where the medical staff are not on site, and the blood pressure values measured are uniformly treated. Therefore, the measured blood pressure value is used to judge that the subject is high. Blood pressure or hypotension is obviously unreasonable.
  • the present application provides a blood pressure measuring instrument capable of detecting state information of a measured part at the same time when measuring blood pressure, so that more reference information is obtained when determining according to the blood pressure value.
  • the present application provides a blood pressure measuring instrument comprising:
  • a pulse wave sensing device for sensing a pulse wave of a detected object and outputting a pulse wave signal.
  • the state sensing device is configured to sense the state of the detected object and output state information.
  • the host includes a signal processing circuit
  • the signal processing circuit is respectively connected to the pulse wave sensing device and the state sensing device, and receives the pulse wave signal output by the pulse wave sensing device and the state information output by the state sensing device, according to the pulse wave signal
  • the blood pressure value is calculated, and the blood pressure is monitored according to the state information of the object to be detected.
  • the present application provides another blood pressure measuring instrument comprising:
  • a pulse wave sensing device for sensing a pulse wave of a detected object and outputting a pulse wave signal.
  • the state sensing device is configured to sense the state of the detected object and output state information.
  • the host includes a signal processing circuit and an output module, wherein the signal processing circuit is respectively connected to the pulse wave sensing device and the state sensing device for receiving the pulse wave signal output by the pulse wave sensing device and the state information output by the state sensing device Calculating a blood pressure value according to the pulse wave signal, and outputting the blood pressure value and the state information; the output module is connected to the signal processing circuit, and displays the blood pressure value output by the signal processing circuit and the state information of the detected object through sound or visibility. Mode output.
  • the blood pressure measuring instrument while obtaining the blood pressure value, senses the state information of the detected object through the state sensing device, and monitors the blood pressure according to the state information of the detected object to ensure that the obtained blood pressure value is more accurate. reliable.
  • FIG. 1 is a schematic block diagram of a blood pressure measuring instrument according to an embodiment of the present application.
  • FIG. 2 is a schematic diagram of the principle of an attitude sensor according to an embodiment of the present application.
  • FIG. 3 is a schematic diagram of a principle of a motion condition sensor according to an embodiment of the present application.
  • FIG. 4 is a schematic structural diagram of a state recognition module according to an embodiment of the present application.
  • FIG. 5 is a schematic block diagram of a blood pressure measuring instrument according to another embodiment of the present application.
  • FIG. 6 is a schematic diagram of a pulse wave in which an interference signal exists in an embodiment of the present application.
  • Fig. 7 is a schematic view showing the pulse wave corrected in Fig. 6.
  • the blood pressure measuring instrument includes a pulse wave sensing device 101 , a state sensing device 100 , and a host 110 .
  • the host 110 includes a signal processing circuit 109 and an output module 105.
  • the signal processing circuit 109 includes a pulse wave acquiring module 103.
  • the pulse wave sensing device 101 is for sensing a pulse wave of a subject to be detected and outputting a pulse wave signal.
  • the pulse wave acquisition module 103 is connected to the pulse wave sensing device 101. In some cases, for example, when the pulse wave acquisition module 103 is far away from the pulse wave sensing device 101, the pulse wave acquisition module 103 and the pulse wave sensing device 101 can be wired or The wireless connection may be performed by a pulse wave transmission device 102.
  • the pulse wave transmission device 102 may specifically be a data line, and the pulse wave transmission device 102 transmits the pulse wave signal output by the pulse wave sensing device 101 to the pulse wave collection.
  • the pulse wave acquisition module 103 processes the pulse wave signals, such as amplification, filtering, and/or analog to digital conversion.
  • the blood pressure calculation module 104 is connected to the pulse wave acquisition module 103 for performing algorithm processing on the collected pulse waves to obtain a blood pressure value.
  • the pulse wave acquisition module 103 is an optional module. When the pulse wave acquisition module 103 is omitted, the analog to digital conversion function can be designed in the blood pressure calculation module 104.
  • the blood pressure measuring instrument can measure the blood pressure by using the oscillometric method.
  • the pulse wave sensing device 101 is a pressure sensor; the blood pressure measuring instrument can also measure the blood pressure by the Korotkoff sound method, and the corresponding pulse wave sensing device 101 is a sound. sensor.
  • the state sensing device 100 is configured to sense a state in which the detected object is located, and output state information.
  • the state identification module 108 is coupled to the state sensing device 100 for collecting state information from the state sensing device 100 and processing the state information.
  • the output module 105 is connected to the blood pressure calculation module 104 and the state recognition module 108, respectively, and outputs the blood pressure value obtained by the blood pressure calculation module 104 and the state information of the detected object processed by the state recognition module 108.
  • the output module 105 may be a sound playing module that outputs the blood pressure value and the state information of the detected object by sound.
  • the output module 105 may be a display module that displays the blood pressure value and the state information of the detected object on the display screen in the form of visibility information.
  • the state sensing device 100 is an attitude sensor 106 for detecting a detected portion of the object to be detected, for sensing the posture of the detected object, and outputting a posture condition signal as status information.
  • the state recognition module 108 is connected to the attitude sensor 106, samples from the attitude condition signal output from the attitude sensor 106, and determines the posture of the detected object based on the attitude condition signal.
  • the state sensing device 100 is a motion condition sensor 107 for setting a measured portion of the detected object, for sensing the motion of the measured portion, and outputting a motion condition signal as the state of the measured portion.
  • Information such as acceleration information or speed information.
  • the state recognition module 108 is connected to the motion condition sensor 107 for collecting a motion condition signal from the motion condition sensor 107, and determining a motion state of the detected portion, for example, a motion speed of the detected portion, according to the motion condition signal, thereby obtaining Know if the detected object is in motion.
  • the state sensing device can include both the attitude sensor 106 and the motion condition sensor 107 for sensing the posture and motion of the detected portion of the detected object, and outputting the attitude condition signal and the motion condition signal.
  • the state recognition module 108 is connected to the attitude sensor 106 and the motion condition sensor 107, respectively, for collecting the attitude condition signal and the motion condition signal from the attitude sensor 106 and the motion condition sensor 107, and determining according to the attitude condition signal and the motion condition signal. The posture and motion of the detected object.
  • the attitude sensor 106 can be a gyroscope or a gravity sensing sensor. Referring to FIG. 2, when the attitude sensor 106 is a gyro sensor, it can output two dimensions of the motion of the measured part, which are the inclination 403 and the twist 404. The two signals can determine the posture of the measured part.
  • the reference plane 401 is rotated to the current posture plane 402 by the inclination 403 and the twist 404.
  • the posture of the measured part is The plane formed by the Y-axis and the Z-axis is parallel; when the inclination is 0 degree and the twist is 90 degrees, the posture of the measured portion (ie, the current posture plane) is parallel to the plane formed by the X-axis and the Z-axis.
  • the state recognition module 108 can determine the posture of the measured part through a corresponding algorithm according to the inclination and the twist, and output through the output module 105.
  • the state recognition module 108 can calculate the motion speed of the measured portion according to the three-dimensional acceleration information, and output it through the output module.
  • attitude sensor 106 is a sensor other than the gyro sensor
  • motion sensor 107 is a sensor other than the acceleration sensor
  • the output signal thereof will be different, but the invention according to the present application can also be obtained. Status information of the part to be tested.
  • the state recognition module 108 specifically implements amplification and filtering processing on the collected signal.
  • the state recognition module 108 includes a carrier circuit 201, a closed loop driving circuit 202, a preamplifying circuit 203, and post processing. Circuit 204.
  • the carrier circuit 201 and the closed loop drive circuit 202 are respectively connected to the state sensing device 100 for modulating the signal of the state information output by the state sensing device 100.
  • the preamplifier circuit 203 is connected to the state sensing device 100 for acquiring state information modulated by the carrier circuit 201 and the closed loop driving circuit 202 from the state sensing device 100, and converting it into a differential voltage signal according to a preset accuracy and gain.
  • the post-processing circuit 204 is connected to the preamplifier circuit 203 for acquiring a differential voltage signal from the preamplifier circuit 203, demodulating it, and obtaining state information of the state in which the object to be detected is located.
  • the post processing circuit 204 includes a first filter amplifying circuit 301, a first demodulating circuit 302, a second filter amplifying circuit 303, a second demodulating circuit 304, a low pass filtering circuit 305, and a DC amplifying circuit 306 which are sequentially connected.
  • the first filter amplifying circuit 301 is connected to the preamplifier circuit 203 for acquiring a differential voltage signal from the preamplifier circuit 203 and performing the first filter amplification.
  • the first demodulation circuit 302 is connected to the first filter amplifying circuit 301, and is configured to obtain the differential voltage signal that has undergone the first filtering and amplification from the first filtering and amplifying circuit 301, and perform the first demodulation, in this embodiment.
  • the first demodulation circuit 302 uses a high-pass filter for filtering DC and low frequency signals in the differential voltage signal, such as noise signals due to signal drift or human breathing.
  • the second filter amplifying circuit 303 is connected to the first demodulating circuit 302 for obtaining the differential voltage signal that has undergone the first demodulation from the first demodulating circuit 302, and performing the second filtering and amplifying thereof.
  • the second demodulation circuit 304 is connected to the second filter amplifying circuit 303, and is configured to obtain a differential voltage signal amplified by the second filtering from the second filter amplifying circuit 303, perform second demodulation, and filter the power supply. The power frequency interference brought.
  • the low pass filter circuit 305 is connected to the second demodulation circuit 304 for obtaining the differential voltage signal after the second demodulation from the second demodulation circuit 304, performing low pass filtering processing on the differential voltage signal.
  • the carrier signal obtains status information of the detected object.
  • the DC amplifying circuit 306 is connected to the low-pass filter circuit 305 for acquiring state information of the detected object from the low-pass filter circuit 305, amplifying the output, and outputting it to the output module 105 for output by sound or visibility display. .
  • DC amplification of the status information can increase the signal strength and facilitate subsequent circuit processing.
  • the first filter amplifying circuit 301 and the second filter amplifying circuit 303 can increase the difference between the differential voltage signal and the noise signal, and improve the demodulation effects of the first demodulating circuit 302 and the second demodulating circuit 304.
  • the state information of the detected object output by the state recognition module 108 may be velocity waveform data indicating the moving speed of the measured portion and waveform data indicating the inclination and the twist of the measured portion, or may be directly the velocity value or indicating the inclination of the measured portion.
  • the value of the degree and the degree of twist, the output module 105 outputs the above waveform or value.
  • the state recognition module 108 may further include a state calculation and recognition module that performs an operation and/or identification based on the state information output by the post processing circuit 204 to determine the motion of the measured portion.
  • the state and/or the posture for example, the state recognition module 108 may further process the state information, and directly output information indicating that the object to be detected is stationary, slight motion, strenuous motion, etc. according to the magnitude of the motion speed of the measured portion, according to the measured portion
  • the direct output of the inclination and the twist indicates information such as standing, lying, lying on the object to be detected, and the sound output or text display is performed through the output module.
  • the observer can judge whether the corresponding blood pressure value is accurate by observing the blood pressure value output by the output module 105 and combining the state information indicating the motion posture of the detected object.
  • the blood pressure measuring instrument includes a pulse wave sensing device 501, a pulse wave transmitting device 502, a pulse wave acquiring module 503, a blood pressure calculating module 504, an output module 505, a state sensing device 500, and a state recognition module 508.
  • the state sensing device 500 is an attitude sensor 506 and/or a motion condition sensor 507.
  • the blood pressure measuring instrument provided in this embodiment is different from the above embodiment in that the state identifying module 508 is connected to the blood pressure calculating module 504, and the blood pressure calculating module 504 acquires the state information of the detected object from the state identifying module 508, and performs blood pressure according to the state information.
  • Monitoring processing for example, participating in the calculation of the blood pressure value, optimizing the calculation result of the blood pressure value, or optimizing the monitoring of the blood pressure value according to the state information of the detected object, for example, when the blood pressure value exceeds the alarm limit, according to the object to be detected.
  • the status information determines whether an alarm message is issued.
  • the blood pressure calculation module 504 detects that the pulse wave suddenly rises or falls, and can determine whether the motion speed of the detected object is greater than or equal to the first set value, and if so, If it is determined that the sudden increase or decrease is caused by external interference, the pulse wave measurement value having the interference is judged as an invalid value, or the pulse wave having the interference is optimized for the segment, for example, according to the pulse wave signal at the occurrence of the mutation
  • the adjacent pulse wave signal sample values correct the pulse wave signal at the sudden change, and the adjacent sample values may be several sample values before the mutation, or may be some sample values before and after the mutation, and then the corrected pulse wave is used.
  • the signal calculates the blood pressure value.
  • whether or not there is a sudden increase or decrease in the pulse wave can be determined based on the change in the slope of the pulse wave. It can also be judged according to the data values A and B of two consecutive sampling points.
  • is within the preset threshold range, it is determined that the pulse wave changes normally, when
  • exceeds the preset threshold range it is determined that the pulse wave suddenly rises or falls.
  • the blood pressure calculation module 504 detects that the pulse wave suddenly rises or falls, it is determined according to the state information whether the sudden increase or decrease is caused by interference. For example, the blood pressure calculation module 504 detects that the state information indicates that the measured part exists.
  • a large speed indicates that the object to be detected is in motion, and it can be judged that the sudden increase or decrease of the pulse wave is caused by external interference.
  • the blood pressure calculation module 504 can fit the abnormal pulse wave according to the condition of the previous several pulse waves, and replace it to achieve the purpose of correcting the pulse wave.
  • the pulse wave is simulated by a sine wave, and the pulse waves at 601 and 602 in the figure can be respectively expressed as follows.
  • Pulse wave at 601: W1 V1Sin ⁇ , where V1 is the amplitude.
  • Pulse wave at 602: W2 V2Sin ⁇ , where V2 is the amplitude.
  • V3 2V2.
  • the 603 pulse wave obtained by the above formula is theoretically obtained according to the pulse wave fitting at 601 and 602. In fact, when the pulse wave at 603 is detected as shown in Fig. 6, the pulse wave suddenly decreases due to the interference.
  • the blood pressure calculation module 504 performs a replacement correction on the pulse wave at 603 according to the above equation, as shown at 604 in FIG. At this point, the correction of the pulse wave with interference is completed.
  • the blood pressure calculation module 504 determines the posture information of the measured part from the state identification module 508. When it is determined that the blood pressure value continues to be lower than the second set value, it may be determined according to the posture information of the detected object. Generate an alarm signal. When the blood pressure value continues to be lower than the second set value and the detected object is in the lying posture, the detected object may be in a sleep state, and an alarm may not be performed. Or the blood pressure calculation module 504 determines whether the posture information of the detected object changes when the pulse wave signal is abruptly changed, and if so, changes the pulse wave signal of the detected pulse as an invalid signal, or according to the pulse wave at which the mutation occurs. The pulse wave signal of the sudden change of the pulse wave signal sample value is corrected, and the blood pressure value is calculated by using the corrected pulse wave signal.
  • the blood pressure measuring instrument provided in the embodiment can automatically correct the pulse wave with interference or optimize the processing of the result according to the motion or posture information of the detected object, thereby improving the accuracy of the blood pressure monitoring.
  • the measured part is usually the arm of the object to be detected, and the blood pressure measuring instrument further includes a sleeve that is placed on the arm or wrist of the object to be detected.
  • Some blood pressure measuring device sleeves are separated from the main unit, and the pulse wave sensing device and the state sensing device are installed at the sleeve end to facilitate sensing the state of the measured portion.
  • Some blood pressure measuring instrument sleeves are integrated with the main unit and are located at the measured position during the detection. In this case, the pulse wave transmitting device can be omitted, and the state sensing device can be installed on the host, directly with the state recognition module.
  • the communication is completed on the host, and can also be installed on the sleeve end, and communicates with the status recognition module installed on the host by establishing a communication link from the sleeve end to the host.
  • the communication link can be wired communication or wireless communication. the way.
  • the blood pressure measuring instrument can also measure blood pressure through other measured parts of the object to be detected, the measured part should not be construed as limiting the present application.

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Abstract

La présente invention concerne une jauge de pression artérielle qui comprend : un appareil de détection d'onde de pouls (101) destiné à détecter une onde de pouls d'un objet détecté et à produire un signal d'onde de pouls ; un appareil de détection d'état (100) destiné à détecter un état dans lequel se trouve un objet sous surveillance, et à produire des informations d'état ; et un hôte (110), comprenant un circuit de traitement du signal (109). Le circuit de traitement du signal (109) est respectivement raccordé à l'appareil de détection d'onde de pouls (101) et à l'appareil de détection d'état (100), reçoit le signal d'onde de pouls produit par l'appareil de détection d'onde de pouls (101) et les informations d'état produites par l'appareil de détection d'état (100), calcule une valeur de pression artérielle selon le signal d'onde de pouls, et réalise un traitement de suivi sur la pression artérielle en fonction des informations d'état de l'objet détecté. Selon la jauge de pression artérielle, le traitement de surveillance est réalisé sur la pression artérielle en fonction des informations relatives à l'état dans lequel se trouve l'objet détecté, assurant ainsi qu'une valeur de pression sanguine obtenue est plus précise et plus fiable.
PCT/CN2013/083099 2012-12-27 2013-09-09 Jauge de pression artérielle WO2014101466A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201210576302.4 2012-12-27
CN201210576302.4A CN103892816B (zh) 2012-12-27 2012-12-27 一种血压测量仪

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CN108523868A (zh) * 2018-06-15 2018-09-14 安徽中科智链信息科技有限公司 用于血压测量的自校准系统和方法
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WO2017049624A1 (fr) * 2015-09-25 2017-03-30 华为技术有限公司 Procédé de mesure de la pression artérielle, dispositif et terminal de mesure de la pression artérielle
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WO2019227329A1 (fr) * 2018-05-30 2019-12-05 深圳迈瑞生物医疗电子股份有限公司 Procédé d'optimisation de mesure de tension artérielle et appareil de mesure de tension artérielle
WO2020044854A1 (fr) * 2018-08-30 2020-03-05 パナソニックＩｐマネジメント株式会社 Dispositif de mesure biologique et procédé de mesure biologique
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