WO2014087149A3 - Device and apparatus - Google Patents
Device and apparatus Download PDFInfo
- Publication number
- WO2014087149A3 WO2014087149A3 PCT/GB2013/053192 GB2013053192W WO2014087149A3 WO 2014087149 A3 WO2014087149 A3 WO 2014087149A3 GB 2013053192 W GB2013053192 W GB 2013053192W WO 2014087149 A3 WO2014087149 A3 WO 2014087149A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- well
- amplification
- volume
- nucleic acid
- channel
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0825—Test strips
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7756—Sensor type
- G01N2021/7759—Dipstick; Test strip
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015544541A JP6272895B2 (en) | 2012-12-03 | 2013-12-03 | Devices and equipment |
AU2013353832A AU2013353832B2 (en) | 2012-12-03 | 2013-12-03 | Device and apparatus |
CA2892980A CA2892980C (en) | 2012-12-03 | 2013-12-03 | Device and method for carrying out an assay to detect a nucleic acid in a sample |
EP13817710.0A EP2925448B1 (en) | 2012-12-03 | 2013-12-03 | Device and method for carrying out an assay to detect a nucleic acid in a sample |
US14/649,126 US10006867B2 (en) | 2012-12-03 | 2013-12-03 | Device and apparatus |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1221726.1 | 2012-12-03 | ||
GB201221726 | 2012-12-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014087149A2 WO2014087149A2 (en) | 2014-06-12 |
WO2014087149A3 true WO2014087149A3 (en) | 2014-08-07 |
Family
ID=49917662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2013/053192 WO2014087149A2 (en) | 2012-12-03 | 2013-12-03 | Device and apparatus |
Country Status (6)
Country | Link |
---|---|
US (1) | US10006867B2 (en) |
EP (1) | EP2925448B1 (en) |
JP (1) | JP6272895B2 (en) |
AU (1) | AU2013353832B2 (en) |
CA (1) | CA2892980C (en) |
WO (1) | WO2014087149A2 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11360076B2 (en) | 2012-03-30 | 2022-06-14 | Weavr Health Corp. | Methods and systems to collect a biological sample |
US11358138B2 (en) | 2013-07-19 | 2022-06-14 | Boston Microfluidics Inc. | Fluid sample collection device |
WO2016069091A1 (en) * | 2014-08-15 | 2016-05-06 | California Institute Of Technology | The pumping lid: devices and methods for programmable generation of positive and negative pressures |
US11376594B2 (en) * | 2015-11-04 | 2022-07-05 | Nitto Denko Corporation | Apparatus and system for biofluid sample dispensing and/or assay |
ES2846973T3 (en) * | 2016-02-15 | 2021-07-30 | Empe Diagnostics Ab | Diagnostic device and related method |
CA3080481A1 (en) | 2017-10-27 | 2019-05-02 | Boston Microfluidics, Inc. | Fluid sample collection device |
KR102227039B1 (en) * | 2017-12-15 | 2021-03-16 | 프리시젼바이오 주식회사 | Driving Method of Diagnostic Apparatus |
EP3801904A4 (en) * | 2018-05-24 | 2022-03-02 | Weavr Health Corp. | Push- or twist- initiated blood metering, filtering and storage |
US11484877B2 (en) | 2018-05-29 | 2022-11-01 | Weavr Health Corp. | Blood metering device with desiccant and support for storage media and inlay with flange |
US11772097B2 (en) | 2018-10-19 | 2023-10-03 | Renegadexbio, Pbc | Simultaneous spot test and storage of blood samples |
US11490839B2 (en) | 2018-10-23 | 2022-11-08 | Weavr Health Corp. | Funnel with extension tube to augment blood collection device |
US11768215B2 (en) * | 2019-01-04 | 2023-09-26 | Funai Electric Co., Ltd. | Digital dispense system cartridge |
CA3154966A1 (en) * | 2019-10-21 | 2021-04-29 | Alex DEHGAN | Systems and methods for determining presence and/or characteristics of target analytes in a sample |
KR102402540B1 (en) * | 2020-04-10 | 2022-05-26 | (주)옵토레인 | Diagnostic chip and diagnostic cartridge having the same |
US11229906B2 (en) * | 2020-06-21 | 2022-01-25 | Mehdi Hatamian | Lateral flow assay housing with integrated sample and buffer solution delivery and measurement |
US11506659B2 (en) * | 2020-06-21 | 2022-11-22 | Mehdi Hatamian | Lateral flow assay housing with integrated sample and buffer solution delivery and measurement |
EP3964292A1 (en) * | 2020-09-07 | 2022-03-09 | Interhealth | Enclosed unit for biological sample processing and uses thereof |
AU2021356770A1 (en) * | 2020-10-07 | 2023-06-01 | Accellix Ltd. | System for determining a biological condition and cartridge therefor |
CN114590475B (en) * | 2020-12-07 | 2023-11-17 | 京东方科技集团股份有限公司 | Liquid storage release device |
TW202235874A (en) * | 2021-01-15 | 2022-09-16 | 普渡研究基金會 | Liquid biological sample test cartridge and heating device |
KR102595551B1 (en) * | 2021-06-23 | 2023-10-30 | (주)옵토레인 | Diagnostic chip having a multi-hydrophilic function |
NL2028817B1 (en) * | 2021-07-23 | 2023-01-30 | Micronit Holding B V | Assembly of a microfluidic device and a cap, cap, microfluidic device and method for introducing fluid into a microfluidic device |
CN113846014A (en) * | 2021-10-29 | 2021-12-28 | 青岛全诊生物技术有限公司 | Nucleic acid extraction and amplification device |
WO2023212776A1 (en) * | 2022-05-03 | 2023-11-09 | Axxin Pty Ltd | Fluidic cartridge kit with dispensing cap |
US20240058809A1 (en) * | 2022-08-16 | 2024-02-22 | Nicole Shamayev | Device and method of portable drug testing |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004065010A2 (en) * | 2003-01-21 | 2004-08-05 | Micronics Inc. | Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing |
WO2008076395A2 (en) * | 2006-12-14 | 2008-06-26 | The Trustees Of The University Of Pennsylvania | Mechanically actuated diagnostic device |
US20100035349A1 (en) * | 2008-08-06 | 2010-02-11 | The Trustees Of The University Of Pennsylvania | Biodetection Cassette with Automated Actuator |
WO2011051735A2 (en) * | 2009-11-02 | 2011-05-05 | The Secretary Of State For Environment, Food & Rural Affairs .. | Device and apparatus |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040110167A1 (en) | 1995-07-13 | 2004-06-10 | Gerdes John C. | Lateral flow system for nucleic acid detection |
US6379929B1 (en) | 1996-11-20 | 2002-04-30 | The Regents Of The University Of Michigan | Chip-based isothermal amplification devices and methods |
US6410275B1 (en) * | 1997-05-02 | 2002-06-25 | Biomerieux, Inc. | Disposable test devices for performing nucleic acid amplification reactions |
US6431476B1 (en) * | 1999-12-21 | 2002-08-13 | Cepheid | Apparatus and method for rapid ultrasonic disruption of cells or viruses |
KR100450818B1 (en) | 2002-03-09 | 2004-10-01 | 삼성전자주식회사 | Multi chamber PCR chip |
CN101832885A (en) * | 2003-11-14 | 2010-09-15 | 因韦尔尼斯医药瑞士股份有限公司 | Rapid sample analysis and storage devices and methods of use |
EP2007903A2 (en) | 2006-04-10 | 2008-12-31 | 3M Innovative Properties Company | Nucleic acid detection using lateral flow methods |
WO2008105814A2 (en) | 2006-08-22 | 2008-09-04 | Los Alamos National Security, Llc | Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids |
DE102007062441A1 (en) | 2007-12-20 | 2009-06-25 | Aj Innuscreen Gmbh | Mobile rapid test system for nucleic acid analysis |
CN102396284B (en) * | 2009-10-30 | 2015-05-06 | 华为技术有限公司 | Method and apparatus of communication of payload data |
GB2483858A (en) | 2010-09-21 | 2012-03-28 | Univ Hull | Amplifying nucleic acids using microfluidic device to perform PRC |
-
2013
- 2013-12-03 AU AU2013353832A patent/AU2013353832B2/en active Active
- 2013-12-03 EP EP13817710.0A patent/EP2925448B1/en active Active
- 2013-12-03 WO PCT/GB2013/053192 patent/WO2014087149A2/en active Application Filing
- 2013-12-03 US US14/649,126 patent/US10006867B2/en active Active
- 2013-12-03 CA CA2892980A patent/CA2892980C/en active Active
- 2013-12-03 JP JP2015544541A patent/JP6272895B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004065010A2 (en) * | 2003-01-21 | 2004-08-05 | Micronics Inc. | Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing |
WO2008076395A2 (en) * | 2006-12-14 | 2008-06-26 | The Trustees Of The University Of Pennsylvania | Mechanically actuated diagnostic device |
US20100035349A1 (en) * | 2008-08-06 | 2010-02-11 | The Trustees Of The University Of Pennsylvania | Biodetection Cassette with Automated Actuator |
WO2011051735A2 (en) * | 2009-11-02 | 2011-05-05 | The Secretary Of State For Environment, Food & Rural Affairs .. | Device and apparatus |
Also Published As
Publication number | Publication date |
---|---|
AU2013353832A1 (en) | 2015-05-28 |
US10006867B2 (en) | 2018-06-26 |
CA2892980C (en) | 2020-12-15 |
AU2013353832B2 (en) | 2017-05-11 |
JP2016506238A (en) | 2016-03-03 |
CA2892980A1 (en) | 2014-06-12 |
EP2925448B1 (en) | 2019-05-22 |
JP6272895B2 (en) | 2018-01-31 |
WO2014087149A2 (en) | 2014-06-12 |
US20150346105A1 (en) | 2015-12-03 |
EP2925448A2 (en) | 2015-10-07 |
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