WO2014068460A3 - Compositions and methods for the treatment of neurologic diseases and neurological disorders - Google Patents

Compositions and methods for the treatment of neurologic diseases and neurological disorders Download PDF

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Publication number
WO2014068460A3
WO2014068460A3 PCT/IB2013/059640 IB2013059640W WO2014068460A3 WO 2014068460 A3 WO2014068460 A3 WO 2014068460A3 IB 2013059640 W IB2013059640 W IB 2013059640W WO 2014068460 A3 WO2014068460 A3 WO 2014068460A3
Authority
WO
WIPO (PCT)
Prior art keywords
formula
compositions
treatment
methods
neurological disorders
Prior art date
Application number
PCT/IB2013/059640
Other languages
French (fr)
Other versions
WO2014068460A2 (en
Inventor
Mahesh Kandula
Original Assignee
Mahesh Kandula
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahesh Kandula filed Critical Mahesh Kandula
Publication of WO2014068460A2 publication Critical patent/WO2014068460A2/en
Publication of WO2014068460A3 publication Critical patent/WO2014068460A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles

Abstract

The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II; and methods for treating or preventing neurologic diseases and neurological disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of partial-onset seizures, infantile spasm, mixed seizure types of Lennox-Gastaut syndrome, myoclonic, generalized tonic clonic seizure, epilepsy, Parkinson's, obesity, migraines and bipolar depression.
PCT/IB2013/059640 2012-11-02 2013-10-25 Compositions and methods for the treatment of neurologic diseases and neurological disorders WO2014068460A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN4577/CHE/2012 2012-11-02
IN4577CH2012 2012-11-02

Publications (2)

Publication Number Publication Date
WO2014068460A2 WO2014068460A2 (en) 2014-05-08
WO2014068460A3 true WO2014068460A3 (en) 2014-12-24

Family

ID=50628192

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/059640 WO2014068460A2 (en) 2012-11-02 2013-10-25 Compositions and methods for the treatment of neurologic diseases and neurological disorders

Country Status (1)

Country Link
WO (1) WO2014068460A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172896A (en) * 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
WO2004063173A1 (en) * 2003-01-10 2004-07-29 Dipharma S.P.A. A process for the preparation of benzo[d]isoxazol-3-yl-methanesulfonic acid and the intermediates thereof
WO2008142134A1 (en) * 2007-05-24 2008-11-27 Neurosearch A/S Benzisoxazole derivatives as potassium channel modulators for the treatment of e.g. respiratory diseases, epilepsy and convulsions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172896A (en) * 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
WO2004063173A1 (en) * 2003-01-10 2004-07-29 Dipharma S.P.A. A process for the preparation of benzo[d]isoxazol-3-yl-methanesulfonic acid and the intermediates thereof
WO2008142134A1 (en) * 2007-05-24 2008-11-27 Neurosearch A/S Benzisoxazole derivatives as potassium channel modulators for the treatment of e.g. respiratory diseases, epilepsy and convulsions

Also Published As

Publication number Publication date
WO2014068460A2 (en) 2014-05-08

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