WO2014050976A1 - Needleless connector - Google Patents

Needleless connector Download PDF

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Publication number
WO2014050976A1
WO2014050976A1 PCT/JP2013/076084 JP2013076084W WO2014050976A1 WO 2014050976 A1 WO2014050976 A1 WO 2014050976A1 JP 2013076084 W JP2013076084 W JP 2013076084W WO 2014050976 A1 WO2014050976 A1 WO 2014050976A1
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WO
WIPO (PCT)
Prior art keywords
valve body
portion
elastic valve
formed
support surface
Prior art date
Application number
PCT/JP2013/076084
Other languages
French (fr)
Japanese (ja)
Inventor
佐野 嘉彦
浩 松尾
鈴木 賢
Original Assignee
二プロ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2012-213139 priority Critical
Priority to JP2012213139 priority
Application filed by 二プロ株式会社 filed Critical 二プロ株式会社
Publication of WO2014050976A1 publication Critical patent/WO2014050976A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/26Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/26Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • A61M2039/261Valves closing automatically on disconnecting the line and opening on reconnection thereof where the fluid space within the valve is increasing upon disconnection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/04Access sites having pierceable self-sealing members
    • A61M39/045Access sites having pierceable self-sealing members pre-slit to be pierced by blunt instrument

Abstract

Provided is a novel needleless connector that can prevent backflow of blood or the like by means of a simple structure. In the needleless connector (10), which is such that an elastic valve body (14) is incorporated within a housing (12) at which a drug duct (28) has been formed, and when a male luer (88) is inserted into a slit (62) of the elastic valve body (14), the elastic valve body (14) opens and the male luer (88) is connected to the drug duct (28), a protruding support surface (32) having a flared inclined surface is formed at the housing (12), the elastic valve body (14) is superposed on the protruding support surface (32) in the state of being in close contact, and at the protruding support surface (32), the slit (62) of the elastic valve body (14) is positioned on the aperture (36) of the drug duct (28) and corrugations are imparted to the outer peripheral surface of the elastic valve body (14) superposed on the protruding support surface (32), forming mountains (60) and valleys (58) extending in the peripheral direction.

Description

Needleless connector

The present invention is used in a liquid flow path such as an infusion route in the medical field, it relates to needleless connector that can be connected to a male luer provided at the syringe or the like for such liquid channel.

In the liquid flow path for performing an infusion or blood transfusion, etc. in the medical field, in order to enable connection and disconnection of a syringe or infusion bag or the like, needleless connector is used. The needleless connector, U.S. Patent No. 6171287 As described in FIG. 1 of the '668 patent the elastic valve body is assembled to the distal end opening portion of the liquid medicine flow passage formed in the housing . Further, the proximal end of the chemical liquid flow path, a catheter inserted into a blood vessel is to be connected.

Then, by placing insert the male luer from the outside with respect to the slit of the elastic valve body, the elastic valve body is opened and the liquid medicine passage and the male luer adapted to be communicated. By flowing a chemical solution inside the needle-less connector from a connected syringe or the like the male luer in this state, it is possible to perform the chemical administered to a patient. Moreover, when the drug solution administered is completed, the male luer is withdrawn from the slit, the slit is closed with the restoration of the elastic valve body. Thus, the front end opening portion of the liquid medicine flow path is blocked by the elastic valve body, so that the connected male luer from the chemical liquid passage to the blood vessel or the like is disconnected.

Incidentally, the needleless connector, when withdrawing the male luer from the slit, the connected to the chemical liquid flow path a catheter blood from the vessel enters the (reflux), there is a possibility that blood clotting occurs. Therefore, needleless connector capable of preventing the backflow of blood when extracting the male luer from the slit is required.

Needleless connector described in Patent Document 1 is of conventional construction, the front end opening portion of the liquid medicine flow channel is spread gradually toward the elastic valve body. However, not the end face of the chemical liquid flow path side is supported in the elastic valve body, so as to enter upon pledged male luer from the outside, the central portion of the elastic valve body from the distal end opening portion of the liquid medicine flow channel inward elastic Deform. As a result, when withdrawing the male luer, along with the restoration deformation of the elastic valve body, and the volume of the chemical liquid channel connected to a blood vessel or the like is increased, the suction force is generated in the blood or the like into chemical liquid flow path , backflow of blood was easy to occur.

In order to prevent the backflow of such blood, in Kohyo 2009-544449 (Patent Document 2), the barrier ribs is a valve body, the structure was embedded hard member to form the inner chamber proposed It is. In the structure described in Patent Document 2, when placed inserted in the distal end portion of such male luer, by volume of the inner chamber increases with the elastic deformation of the partition wall, the volume of the inner chamber is reduced during withdrawal of the distal portion backflow of blood or the like is adapted to be prevented Te.

However, even in the structure described in Patent Document 2, when put insert the fore-end portion of the male luer against the septum is a valve body, although the inner chamber is widened, deformed to such partition walls from entering the inner chamber from, after all the volume expansion of the inner chamber is hardly sufficiently achieved, there is a problem that hardly backflow prevention effect is sufficiently exhibited, such as blood, of interest. Moreover, it is a composite structure of the partition wall is rigid member is a valve body, the shape also a problem that it is difficult to manufacture because it is complicated. Furthermore, since the elastic deformation of the partition is an elastic body is restrained by the rigid member, in addition to that there is a possibility that the operation deformation stiffness is increased becomes difficult, cracking is a concern due to concentration or the like of the deformation stress , there is also a problem that it is difficult to obtain a sufficient durability.

US Pat. No. 6171287 JP-T 2009-544449 JP

Here, the present invention was made of the above-described circumstances as a background, and has as its problem to be solved, providing a novel needleless connector that can prevent backflow of blood or the like with a simple structure It is to.

A first aspect of the present invention has been made to solve the above problem, the elastic valve body in a housing chemical liquid flow path is formed is built, the male luer into the slit of the elastic valve body inserted insertion in is the needleless connector elastic valve body is male luer is connected to the chemical solution flow path open, projecting support surface having an inclined surface of the flared in the housing is formed, protruding shape the elastic valve body is superposed in close contact against the support surface, the projecting like support surface, together with the slit of the elastic valve body on the opening of the drug solution flow paths are brought into position, projecting wherein the Jo support surface and superimposed elastic valve body irregularities attached to an outer peripheral surface extending in the circumferential direction troughs of the crest is formed.

The needleless connector according to the present embodiment, by superposition of elastic valve body in close contact against the protruding support surface, the slit expanding direction elastic valve body when inserted put the male luer is along the projecting support surface spread press elastically deformed. Thus, the elastic valve body is prevented from entering the chemical liquid flow path side when inserted put the male luer, the volume between the only resilient valve body and projecting supporting surface amount that the slit is widened to increase surely. Therefore, when the withdrawn male luer, volume reduction amount slit had spread closes corresponding to a partial becomes possible to generate a positive pressure (positive pressure) in chemical liquid flow path, effectively the backflow prevention such as blood It can act.

Moreover, the needleless connector of the present embodiment, by valleys and crests on the outer peripheral surface of the elastic valve body superimposed in close contact with the projecting support surface is formed, the elastic partially in the elastic valve body different has been deformed easily portion and hard portion is formed. Therefore, a direction away when the elastic valve body is deformed along the projecting support surface when inserted put the male luer, the projecting support surface so as to bend in easily portion deformed by valleys outward easy bending deformation occurs.

Thus, inserted insertion operation of the male luer can be easily deformed rigidity of the elastic valve body is small. Further, the elastic valve body, by bending deformation so as to be separated outward from the protruding support surface, the gap between the contact by elastic valve body and projecting support surface in the initial state is reliably and stably likely to occur become. By this gap is generated stably, it could be implemented volume increase in the elastic valve body when placed cuttings of the male luer is large and stable, a greater positive pressure to the liquid medicine flow channel upon withdrawal of the male luer It is generated, a further improvement of the backflow prevention effect of blood or the like can be achieved.

In the present embodiment, the valleys and crests is a relative part of the height at the outer peripheral surface of the elastic valve body, a relatively concave portion called a valley, a portion of the relatively convex that the crest. Further, valley and peak portions need not be adjacent to each other, it may be provided apart not intended to be limited to the number, shape, etc..

A second aspect of the present invention, there is provided a needleless connector according to the first aspect, which irregularities on the outer peripheral surface of the elastic valve body, there is a smoothly curved cross-sectional shape having no corner portion it is.

In this embodiment, the outer peripheral surface of the elastic valve body, that the generation of the corner due to the provision of the valleys and crests are avoided, cracking is prevented durability due to concentration of deformation or stress It is improved.

A third aspect of the present invention, there is provided a needleless connector according to the first or second aspect, the elastic valve body, and a thin portion that is superimposed on the skirt side region of said projecting support surface, said and a thick portion that is superimposed on top side area of ​​the projecting support surface is configured comprise, in which the valleys are formed on the outer peripheral surface of the upper end portion of the thick portion.

In this aspect, the thick portion of the thickness dimension is large and the deformation stiffness by increases tend elastic valve body will be soft deformation is achieved, whereby the male luer inserted insertion also facilitated Become.

A fourth aspect of the present invention, there is provided a needleless connector according to any of embodiments of the first to third, the elastic valve body, and a thin portion that is superimposed on the skirt side region of said projecting support surface and a thick portion that is superimposed on top side area of ​​the projecting like support surface, comprise are configured, in which the valleys between the ridges on the outer peripheral surface of at least the thick portion is formed is there.

In this embodiment, the thick portion of the deformable rigidity tends to increase the elastic valve body, by adjusting the size and shape of the valley and the crest provided on its outer peripheral surface, the number and the like, a slit barrier properties required and, inserted insertion operability of the male luer, the backflow prevention effect of blood or the like during further male luer drawing, it is possible to set more properly and greater freedom. That is, while facilitating the deformed insert insertion operation of the male luer utilizing ease is realized by valleys, to ensure blocking of the slits by using an elastic strength that is achieved by the crests, further, valleys crest it is possible to obtain an excellent anti-reflux effect during stable bulge utilized to the male luer drawing deformation outward realized in cooperation with the.

A fifth aspect of the present invention, there is provided a needleless connector according to any of embodiments of the first to fourth, the elastic valve body, and a thin portion that is superimposed on the skirt side region of said projecting support surface and a thick portion that is superimposed on top side area of ​​the projecting like support surfaces are configured comprise, in which the valleys between the ridges on the outer peripheral surface of at least said thin portions are formed .

In this embodiment, originally in the male luer inserted placed easily deformable thin portion upon by being a and tapered at the thin, the manner of its deformation, can be preset by troughs and crests, whereby, it is possible to generate more stable deformation bulge outward at the thin portion.

A sixth aspect of the present invention, there is provided a needleless connector according to any of embodiments of the first to fifth, provided the valley and the crest is over the entire circumference of the outer peripheral surface of the elastic valve body it is what is.

In the present invention need not be provided on the entire circumference of the valley and mountain portion necessarily elastic valve body, in accordance with this embodiment, by providing successively over the peaks and valleys all around, inserted male luer the bulge deformation outward of the elastic valve body can be further increased at the time of putting. Thus, by generating a greater positive pressure to the liquid medicine flow channel upon withdrawal of the male luer, further improvement of the backflow prevention effect of blood or the like can be achieved.

A seventh aspect of the present invention, there is provided a needleless connector according to any of embodiments of the first to sixth, with the outer periphery of the elastic valve body is covered with the housing, and their elastic valve body housing in which the internal space to permit deformation of the outer peripheral side of the elastic valve body is provided between the.

In this embodiment, while well tolerated elastic deformation to the outside of the elastic valve member by the inner space, comprising substantially the entire elastic valve body can be protected by the housing. As a result, damage or due to that other member interferes, problems such as the inhibition of the elastic deformation can be prevented against the elastic valve body. In particular, in the present invention, for example, by providing a deformation space of the elastic valve body to the inside of the elastic valve body, it is also possible to allow the elastic deformation away outwardly from the projecting support surface elastic valve body, the in embodiments, while the elastic valve body and protects the cover at the housing, a deformation away from the projecting support surface, it is also possible to allow the more simple structure with an elastic valve body.

An eighth aspect of the present invention, there is provided a needleless connector according to the seventh aspect, in which the space communicating passage for communicating the interior space to the exterior space is formed.

In this embodiment, when expanded deformation of the elastic valve body by inserting insertion of the male luer, deformation resistance due to the air spring deformation allowing space is avoided. Thus, it is possible to put more easily insert the male luer to the elastic valve body, it is easy gap even further occur between the elastic valve body and projecting support surface, backflow of blood or the like during removal of the male luer further improvement of the preventing effect is also achieved.

A ninth aspect of the present invention, there is provided a needleless connector according to any of embodiments of the 1-8, wherein the elastic valve body, a pair of extending each outer peripheral side in both end portions of the penetrating direction of the slit flange portion is integrally formed, the outer peripheral edge portions of the pair of flange-like portion in which is fixedly supported in each said housing.

In this embodiment, by fixing supporting the elastic valve member to the housing in a pair of flange-like portion, easily and highly secure the fluid-tightness against the external space of the liquid medicine passage formed in the slit of the elastic valve body it becomes possible.

A tenth aspect of the present invention, the a needleless connector according to any of embodiments of the 1-9, and the second valve body is provided to be superposed on the outer end surface of the elastic valve body, said the male luer is inserted slits placed provided on the second valve body, in which are formed in the direction superimposed to intersect with the slits of the elastic valve body.

In this embodiment, in any of the elastic valve body and second valve body, the slit is opened and closed is switched communication / shutoff of the chemical liquid flow path on the basis of the elastic deformation due to the insertion of the male luer. These two valve body, by the respective slits are superimposed in a state crossing, may further improve the sealing property is achieved against the external space of chemical liquid flow path during the insertion of the male luer.

An eleventh aspect of the present invention, there is provided a needleless connector according to any of embodiments of the first to 10, at least the tip portion of the projecting support surface is a Nagayama shape extending with a ridge-shaped top together, the slit of the elastic valve body in which are superimposed in a state extending along the top of 該稜 linear.

In this embodiment, the elastic valve body disposed in close contact is a shape corresponding to the projecting support surface Nagayama shape the projecting support surface, both side portions sandwiching the slit, projecting support surface ridge-like the while it is guided along both sides slope across the top, so that the elastically deformed in the direction of expanding the slit. Therefore, I and spreading direction of the guiding action and slit by projecting support surface coupled with the elastic deformation of the elastic valve body is generated more efficiently and stably. Thus, the greater the gap between the elastic valve body and projecting support surface and stably generated by inserting insertion of the male luer, the backflow prevention such as blood upon removal of the male luer is more effectively achieved that.

A twelfth aspect of the present invention, there is provided a needleless connector according to any of embodiments of the first to 11 in the chemical liquid flow path, the distal end portion which is open to the top of said projecting support surface, the cross-sectional area are those with a throttled nozzle shape.

In this embodiment, the distal end opening portion of the liquid medicine flow channel opening into the protruding support surface, since it is a small opening area, and more are problems such as entering the tip opening elastic valve body is applied during inserted put the male luer It is effectively prevented.

The structure has been needleless connector according to the present invention, by valleys and crests on the outer peripheral surface of the elastic valve body is provided, at the time of putting cuttings of the male luer, to flex with easily deformable around valley elastic valve body is deformed. Thus, the elastic valve body, the elastic deformation toward the direction away from the projecting support surface becomes possible to generate with stable shape, predetermined gap between the elastic valve body and projecting support surface when inserted insertion of the male luer It is stably generated. As a result, the positive pressure generated on the basis of the gap according to the time of withdrawal of the male luer is lost, backflow prevention effect, such as blood, it can be effectively and stably exhibit.

Longitudinal sectional view of a needleless connector of the first embodiment of the present invention. II-II sectional view of Fig. Perspective view of the base housing constituting the needleless connector shown in Figure 1. Perspective view of an elastic valve body constituting a needleless connector shown in Figure 1. A front view of the elastic valve body shown in FIG. Side view of the elastic valve body shown in FIG. VII-VII sectional view of FIG. VIII-VIII cross-sectional view of FIG. Explanatory view showing a inserted placed state of the male luer in the needleless connector shown in FIG. Longitudinal sectional view of a needleless connector of the second embodiment of the present invention. XI-XI cross-sectional view of FIG. 10. Perspective view of an elastic valve body constituting a needleless connector shown in FIG. 10. A front view of the elastic valve body shown in FIG. 12. Side view of the elastic valve body shown in FIG. 12. XV-XV sectional view of FIG. 14. XVI-XVI sectional view of FIG. 13. Explanatory view showing a inserted placed state of the male luer in the needleless connector shown in Figure 11. A front view corresponding to FIG. 5 of the elastic valve body in Comparative Example. Side view corresponding to FIG 6 of the elastic valve body shown in FIG. 18.

Hereinafter, to clarify the present invention more specifically, embodiments of the present invention will be described with reference to the drawings. First, in FIG. 1 and 2 are needleless connector 10 as a first embodiment of the present invention is shown. The needleless connector 10, with respect to the housing 12, and the upper valve 16 as the lower valve 14 and the second valve body as an elastic valve body there is a built-in structure. In the following description, the vertical direction refers to the vertical direction in FIGS.

More particularly, the housing 12 is a divided structure, the base housing 18 of the composed base end side downward in FIG. 1 is configured to include a distal side of the cover housing 20 made of an upper 1 .

Base housing 18 is a peripheral wall portion 24 is provided apart on the outer peripheral side of the cylindrical portion 22 extending on the center axis, between the upper end portions of cylindrical portion 22 and the peripheral wall portion 24 integrally with the upper bottom 26 it has been linked. Further, the cylindrical portion 22 is projected from the peripheral wall portion 24 downwardly, chemical liquid flow path 28 is formed inside the cylindrical portion 22. On the other hand, the locking groove 30 on the inner peripheral surface of the peripheral wall portion 24 is formed.

The intravascular catheters (not shown) is adapted to be connected to the proximal end opening portion of the cylindrical portion 22 of the base housing 18. In the present embodiment, is constituted luer structure of the lock type by a cylindrical portion 22 and the peripheral wall portion 24, the catheter is reliably connectable.

Moreover, as also shown in FIG. 3, the upper end face of the base housing 18 the tubular portion 22 and the peripheral wall portion 24 are connected by the upper bottom 26, projecting substantially chevron upward in the central portion projecting supporting surface 32 is formed. At least the tip portion of the projecting supporting surface 32 (upward in FIG. 3), the top 34 extending ridge shape is formed. Thus, in the present embodiment, the projecting support surface 32 is as a whole Nagayama shape.

Incidentally, the chemical liquid flow path 28 formed in the tubular portion 22 is open at the upper front end portion, is reduced cross-sectional area, there is a nozzle-like tip opening 36. Then, the nozzle-shaped distal end opening portion 36 is opened in the center of the top portion 34 extending ridge shape in the protruding support surface 32.

Further, in the present embodiment, as shown in FIGS. 1-3, the protruding support surface 32, from the top of the substantially throughout reaching the skirt constant inclination angle and has been flared tapered shaped It is inclined. That is, the projecting support surface 32 is not provided break point and bending point in the middle portion in the height direction is an inclined surface in the vertical direction extends substantially linearly. However, in the present invention, the inclined surface of the projecting support surface 32 is not limited to the linear shape, it may be curved, one in the middle in the height direction or a plurality of the break points and bending points it may have.

Furthermore, in the present embodiment, the projecting support surface on the 32, linear communicating groove 37 that extends from the top 34 downward is formed. In particular, in this embodiment, a pair of communicating grooves 37a in the lateral direction in FIG. 1, the 37a are formed, a pair of communicating grooves 37b in the lateral direction in FIG. 2, 37b are formed. The pair of communicating grooves 37b, 37b are linearly formed to the lower end skirt of the projecting support surface 32 extends out from the distal end opening portion 36 of the liquid medicine flow channel 28 is a center of the top portion 34.

Note that the upper end face of the base housing 18, an annular flat surface 38 of the outer circumferential side extends in the circumferential direction at a predetermined width of the projecting support surface 32 (see FIG. 3) is formed, the outer peripheral edge of the flat surface 38 the section outer peripheral collar 40 which protrudes in a cylindrical shape upward is integrally formed. Further, the outer peripheral surface of the base housing 18, a step 42 for positioning and fixing the cover housing 20 is formed.

Such base housing 18 cooperates with the cover housing 20 constituting the housing 12, as shown in FIGS. 1 and 2, has a cylindrical shape of stepped as a whole. That is, such a cover housing 20 includes a cover body 44 having a large diameter cylindrical, a connection port portion 46 having a small-diameter cylindrical shape is integrally connected by the upper bottom 48 of the ring-shaped plate.

Then, the cover body 44 which is open downward, is assembled from above the base housing 18, the opening of the cover body 44 is fitted on the outer circumferential surface of the base housing 18. The opening portion of the cover body 44 is in a state of being positioned in the axial direction by the step 42 of the base housing 18, and is fixed to the base housing 18 by press-fitting or welding, fixing means such as adhesive.

By the cover housing 20 is assembled to such a base housing 18, above the base housing 18, the internal region covered around by the cover housing 20 is formed. Moreover, such internal region through the joint port 46 of the cover housing 20, and is opened upward. Note that the outer peripheral surface of the joint port 46, the lock grooves 50 are formed. In addition, each peripheral wall of the cover body 44 and the joint port 46, an air vent hole 52 penetrating the inside and outside are formed.

Then, the inner region formed in such housing 12 described above, the lower valve 14 and the upper valve 16 is incorporated.

Expanding the lower valve 14, as shown in FIGS. 4-8, having a valve body portion 54 of the thick portion having a block shape, the outer peripheral surface shape that extends in a tapered shape at the lower side of the valve body portion and a diameter portion 56. Although the outer peripheral surface shape of the valve body portion 54 is not limited in particular, it has a substantially elliptic cylindrical shape in this embodiment.

Further, the outer peripheral surface of the lower valve 14, are assigned irregularities extending in the circumferential direction. Thus, in this embodiment, the outer peripheral surface of the valve body portion 54, each one of troughs 58 and crests 60 are formed in an annular shape extending continuously over the entire circumference of each circumferential direction. Such troughs 58, while being formed on the outer peripheral surface of the upper end portion of the valve body portion 54, the crest 60 is formed on the outer circumferential surface of the lower end portion of the valve body portion 54.

Furthermore, in the present embodiment, since the enlarged diameter portion 56 from the lower end of the valve body portion 54 is spread in a tapered shape, even boundary portion between the valve body portion 54 and the enlarged diameter portion 56, all of the lower valve 14 valleys 58 extending over the circumference.

Further, as shown in FIGS. 7-8, irregularities formed on the outer circumferential surface of the lower valve 14 is formed in a smooth curve with no corners. Thus, the outer peripheral surface of the valve body portion 54 and the enlarged diameter portion 56, as a whole, including the respective valley portions 58 and ridge portions 60, there is a smoothly curved cross-sectional shape having no break point.

Incidentally, the two-dot chain line in FIG. 5-8, the valve body portion 54, which represents the outer peripheral surface shape of the virtual not troughs 58 and crests 60 are formed due to the unevenness. That is, the outer peripheral surface shape of the valve body portion 54 revealed by this imaginary line is the oval cylindrical base shape.

In the central portion of the valve body portion 54, a slit 62 is formed through the vertical direction. In the present embodiment, as described above, the cross section of the valve body portion 54 are the outer peripheral surface shape of the oval, slit 62 extends in the longitudinal direction of the oval. Further, the outer peripheral surfaces of the upper and lower ends of the valve body portion 54, in the through direction end portion of the slit 62, a pair of flanges 64, 64 are spread are integrally formed, each outer periphery side.

Further, the lower valve 14, while the upper surface is a flat surface, in its lower end surface, a recess 66 which opens in the central portion is formed. The inner peripheral surface shape of the recess 66 is a tapered surface shape corresponding to the projecting support surface 32 of the aforementioned base housing 18. Specifically, the recess 66 is a tapered surface of the elliptical shape expanding gradually toward the opening at the lower end.

The inner peripheral surface of such recess 66 is substantially the same angle of inclination and the outer peripheral surface of the enlarged diameter portion 56. By interior recess 66 of the enlarged diameter portion 56 is formed, the enlarged diameter portion 56 is a thin portion of the tapered cylindrical shape. The upper recess 66 extends out to the axially intermediate portion of the valve body portion 54 which constitutes the thick portion.

On the other hand, the upper valve 16, as shown in FIGS. 1 and 2, includes a valve body portion 68 extending in the vertical direction in the cross-sectional shape of substantially flat elliptical outer periphery of the upper and lower ends of the valve body portion 68 on the surface, a pair of flanges 70, 72 are integrally formed. In the central portion of the valve body portion 68, a slit 74 is formed through the vertical direction. The slit 74 is of flat oval in cross-section of the upper valve 16 extends in the axial direction, and linearly vertically penetrating.

In a state where the upper valve 16 to the upper end surface of the lower valve 14 (outer end face) are superimposed, these lower valve 14 and the upper valve 16 is incorporated in the housing 12.

Here, the lower valve 14, for the recess 66, is assembled in the projecting support surface 32 but crowded fits state of the base housing 18, the inner surface of the recess 66 is projecting support surface 32 It is superimposed in a substantially close contact substantially over the entire surface. That is, the skirt-side region of the projecting support surface 32 of the base housing 18, together with the inner peripheral surface of the enlarged diameter portion 56 constituting the thin portion are overlapped in the lower valve 14, the top side of the projecting support surface 32 in the region, the valve body portion 54 which constitutes a thick portion in the lower valve 14 is superimposed.

The flange portion 64 of the lower side of the lower valve 14 is superimposed substantially close contact state with respect to the flat surface 38 of the base housing 18 at the outer peripheral side of the projecting support surface 32. On the other hand, the lower valve 14 on the upper side of the flange 64, the lower side of the flange portion 72 of the upper valve 16 is superimposed, is approximately two flange portions 64, 72 which is the same outer diameter, the cover housing 20 It is superimposed on the lower surface of the upper base portion 48.

Further, the housing 12 has holding sleeve 76 of cylindrical shape is incorporated, it is arranged extrapolation state to the valve body portion 54 of the lower valve 14. The pressing sleeve 76 is in a state of being positioned fitted into the lower end portion to the outer peripheral collar 40 of the base housing 18 is assembled between the upper and lower flange portions 64, 64 of the lower valve 14. Here, in the present embodiment, the height of the presser sleeve 76 (vertical direction in FIG. 1) is slightly larger than the facing surface distance between the pair of upper and lower flanges 64, 64 of the lower valve 14. Thereby, the axial lower end face of the pressing sleeve 76, the outer peripheral portion of the lower flange portion 64 of the lower valve 14 is sealed and fixed pressed against the flat surface 38 of the base housing 18. Further, the upper axial end face of the pressing sleeve 76, each outer peripheral portion of the lower side of the flange portion 72 of the upper flange portion 64 and the upper valve 16 of the lower valve 14 superimposed to each other, the upper base portion of the cover housing 20 48 pressed against the to be sealed fixed.

Then, the internal region formed by being surrounded by the base housing 18 and the cover housing 20 described above, on the outer peripheral side of the valve body portion 54, the deformation of the internal space to allow elastic deformation of the outer peripheral side of the lower valve 14 allowing space 78 is formed. In particular, in the present embodiment, the pressing sleeve 76 are spaced outwardly from the outer circumferential surface of the valve body portion 54 of the lower valve 14, between the sleeve 76 pressing these valve body portion 54, i.e., the lower valve 14 deformation allowing space 78 between the facing surfaces of the pair of upper and lower flanges 64, 64 are formed. Further, the pressing sleeve 76, (two in this embodiment) through holes 80 in the radial direction one or more together is formed, the gap between the cover body 44 of the retainer sleeve 76 and the cover housing 20 82 is formed. Thus, the through-hole 80 and the gap 82, the air vent hole 52, the space communicating passage communicating the deformation allowing space 78 to the external space is formed.

Further, the upper valve 16, the valve body portion 68 are disposed in the joint port 46 of the cover housing 20, the upper flange portion 70 of the upper valve 16, is superimposed on the upper opening end face of the connection port portion 46 there. Between the connection opening 46 and the valve body portion 68, to permit in the direction (lateral direction in FIG. 1) perpendicular to the direction in which extends the slit 74, the elastic deformation of the valve body portion 68 deformation allowing space 84 is formed.

The lower valve 14, the long axis direction of the valve body portion 54, so as to extend in the ridgeline direction of the top 34 and Nagayama shape in the protruding support surface 32 is aligned in the circumferential direction relative to the base housing 18 ing. Accordingly, the slit 62 as the valve hole of the lower valve 14, extends along the edge shape of the top portion 34 of the projecting support surface 32 of the base housing 18. Incidentally, the slits 62, before insertion of the male luer 88 to be described later is in contact state, not open. Further, as described above, the lower side of the lower valve 14, the distal end opening 36 of the liquid medicine passage 28 of the tubular portion 22 opens to the center of the top portion 34 extending ridge shape in the protruding support surface 32 .

Furthermore, in the present embodiment, the slits 74 as the valve hole of the upper valve 16, while extending slit 62 substantially perpendicular direction of the lower valve 14 are assembled are positioned in the circumferential direction. Thus, on the center axis extending through the intersection of the slits 74 of the slit 62 and the upper valve 16 of the lower valve 14 in the vertical direction, the distal end opening 36 of the liquid medicine flow channel 28 of the base housing 18 is adapted to position there.

Needleless connector 10 having the above such construction, intravascular catheters or the like (not shown) to the base end opening of the liquid medicine flow channel 28 is used by being connected as described above. Then, under such a use condition, as shown in Figure 9, from above, the male luer 88, such as a syringe 86 to the slits 74,62 of the upper valve 16 and lower valve 14 through the connection port portion 46 of the housing 12 by being inserted placed, each slit 74,62 is expanded, the male luer 88 is a communication to a liquid medicine flow channel 28.

The male luer 88 of the syringe 86 shown in FIG. 9 is a luer lock structure of the male, so that the connected state is reliably maintained with respect to the connection port portion 46 of the housing 12. The male luer 88 is not only a luer lock structure to be fixed with screws, may be a lure slip structure for fixing by inserting.

Here, when put insert the male luer 88 to needleless connector 10 is pushing force of the male luer 88 is exerted to the lower valve 14, the central portion of the valve body portion 54 of the lower valve 14 is pressed downward It is. Along with this depressed, the lower surface of the valve body portion 54, so that the deformed so as to be spread to both sides of the slit 62 along the projecting support surface 32 which is a close contact state. At that time, the lower valve 14, the elastic is different in part by the troughs 58 and the crests 60 formed on the outer peripheral surface. Therefore, when the lower valve 14 is deformed along the projecting support surface 32 when inserted put the male luer 88, deformed so as to bend the troughs 58 are more likely to occur.

As a result, the smaller the deformation rigidity of the lower valve 14 at the time of inserting insert the male luer 88, it is possible to easily perform the insertion operation of the male luer 88. Also, when you put insert the male luer 88, easily deformable and shape-retaining transgression cooperation with hardly deformed ridges 60 around a curved near the valleys 58, outwardly from the projecting support surface 32 between the lower valve 14 and the projecting support surface 32 that is bent and deformed so as to be separated, so that the gap 90 is generated with a reliably stable and large volume. Gap 90 extending in the circumferential direction, a pair of communication holes 37a which are formed on the projecting support surface 32, 37a and a pair of communication holes 37b, by 37b, the chemical liquid flow path 28 and expanded by the lower valve 14 with respect to the slit 62, it is passed more reliably and stably communicate with.

Accordingly, it generated greater positive pressure chemical liquid flow path 28 upon removal of the male luer 88 (positive pressure) is, the backflow prevention effect of blood or the like can be more effectively and stably exhibit. That is, when the withdrawn male luer 88, in addition to volume reduction amount slit 62 which has been spread is closed corresponding to a partial gap 90 that occurred between the lower valve 14 and the projecting support surface 32 is lost it is the volume reduction amount due to be occur, it is prevented completely the occurrence of negative pressure caused by the extraction of the male luer 88 is the backflow prevention effect of the blood or the like is stably exhibited.

Further, the needleless connector 10 of the present embodiment, the inclined surface forming a projecting bearing surface 32 is a straight shape in vertical cross section, it does not have a break point or bending point. Therefore, it is easy adhesion between the recess 66 of the projecting support surface 32 and the lower valve 14 is more stably achieved, after extraction of the pre-insertion, and the male luer 88 of the male luer 88, the projecting support surface 32 gap like hardly occurs by the production error or the like between the recess 66. Thus, between the projecting support surface 32 and the recess 66, the gap 90 is not formed before insertion of the male luer 88 can be reliably formed during male luer 88 inserted. Furthermore, to ensure during removal of the male luer 88, it is possible to generate a positive pressure due to the volume reduction.

Incidentally, by changing the number and shape of the troughs 58 and crests 60 are formed on the outer peripheral surface of the lower valve 14, the gap between the projecting support surface 32 and the recess 66 when the male luer 88 inserted 90 it is also possible to adjust the shape and size. In other words, the valleys 58 and the position and number of the ridges 60, by adjusting the size and shape, the elastic deformation rigidity and elasticity variation of the lower valve 14 at the time of insertion of the male luer 88, the gap 90 size, and the like adjusted to, it is also possible to adjust the size, etc. of the positive pressure at the time of sampling of the insertion resistance and the male luer 88 of the male luer 88 as appropriate.

Furthermore, in the present embodiment, the deformation allowing space 78 through hole 80 and the gap 82 formed on the outer periphery of the lower valve 14, since it communicates with the outside space through the air vent hole 52, such as the aforementioned lower valve 14 not inhibited the action of the air spring of the elastic deformation and effect deformation allowing space 78 based thereon, can more be more advantageously exhibited. However, the external communication passage is not essential in the present invention, it is also possible the deformation allowing space 78 to a sealed structure.

Next, there is shown a needleless connector 92 of the second embodiment of the present invention in FIGS. 10 and 11. In the following description, the same members and portions as the first embodiment, in the figure, indicated by the same reference numerals as the first embodiment, the detailed description thereof is omitted. In the present embodiment, the shape of the lower valve 94 constituting the needleless connector 92 is different from the lower valve 14 of the first embodiment, FIG. 12-16, the lower valve 94 of the present embodiment is shown ing.

The bottom valve 94 of the present embodiment, as shown in FIG. 13 and 14, are formed irregularities extending in each circumferential direction with respect to both the outer peripheral surface of the valve body portion 54 and the enlarged diameter portion 56 there. Thus, the outer peripheral surface of the valve body portion 54, the ridges 60 extending central portion in the height direction in the circumferential direction is formed, the valleys 58 and 58 is provided extending vertically opposite side portions, each circumferential direction It is. Further, the outer peripheral surface of the enlarged diameter portion 56, a trough portion 58 extending intermediate portion in the height direction in the circumferential direction and 2 Tsunoyama portion 60, 60 on both sides thereof are provided. Incidentally, all of the troughs 58 and the crests 60 of the valve body portion 54 and the enlarged diameter portion 56, like the first embodiment, is formed with a connecting surface shape smoothly curved lines.

In needleless connector 92 of the present embodiment in which the lower valve 94 has such a shape is incorporated, as shown in Figure 17, the male luer 88, such as a syringe 86 from the connecting port 46 of the housing 12 by being inserted placed, each slit 62, 74 of the lower valve 94 and upper valve 16 is expanded, the male luer 88 is a communication to a liquid medicine flow channel 28. At that time, the lower valve 94, the valleys 58 and ridges 60 formed on the outer peripheral surface, since the elastic characteristics and variations are properly set, as in the first embodiment, the lower valve 94 so that the gap 90 is stably formed with a large volume between the recess 66 and the projecting support surface 32 of the. As a result, easier and insert operations of the male luer 88, the backflow prevention effect of the blood, such as during sampling of the male luer 88, is being fully exhibited.

In this embodiment in particular, the valleys 58 and ridges 60 irregularities are formed on the outer peripheral surface in the enlarged diameter portion 56 in addition to the valve body portion 54 of the lower valve 94 is provided. Therefore, it is possible to set the elastic deformation mode of the lower valve 94 at the time of insertion of the male luer 88, the shape of interest throughout the valve body portion 54 and the enlarged diameter portion 56, the lower valve 94 the backflow prevention effect of blood or the like at the time of removal of the elastic deformation and thus the male luer 88 can be further set such a large degree of freedom.

[Example]
And prototype needleless connector constructed in accordance with the first embodiment and the second embodiment, an experiment was conducted to confirm the backflow prevention effect of blood. Such experimental results are shown below as Examples 1 and 2.

As a comparative example, was prepared the lower valve 96 having a shape shown in FIGS. 18 and 19, were prepared that assembled the lower valve 96 instead of the lower valve 14 in needleless connector 10 of Example 1 . Then, the needleless connector as a comparative example assembled with the lower valve 96, shown together the results of the same experiment as in Example 1, as a comparative example below. The lower valve 96 as a comparative example, the valve body portion 54 of the lower valve 14 in the first embodiment, be one having an outer peripheral surface of the base shape shown in phantom in FIGS Te, the shape and dimensions of the other parts is the same as the bottom valve 14 of the first embodiment.

That is, in withdrawal of the syringe from the needle-less connector, when the liquid surface of the distal end portion of the side opposite to the side connected to the needleless connector of the cannula is moved closer to the needleless connector side draws corresponds to backflow of blood There is judged to have occurred, the liquid level in the cannula opposite is determined to spit when spaced moved from needleless connector occurs. Also, in each case, it was measured pull-in amount or discharged amount by multiplying the cannula inner diameter to the amount of movement of the liquid level within the cannula.

The results of the experiment, in the first exemplary structure is needle-less connector of the first embodiment according to the invention, upon withdrawal of the syringe, retraction also not observed once, is discharged in all of the measurement is confirmed, the discharged amount It was in the range of 8 ~ 20μL. Further, the needleless connector of the second embodiment, upon withdrawal of the syringe, retraction also not observed once, been discharged in all measurement confirmation, the discharged amount was in the range of 1 ~ 3 [mu] L. On the other hand, the needle-less connector of the comparative example, the time of withdrawal of the syringe, pull-in was observed.

The experimental results described above, the needleless connector constructed according to the present invention, as compared with the needleless connector of the comparative example, it is recognized that can exert blood backflow prevention effect of the time of withdrawal of the syringe. In addition, by comparing the experimental results of the first embodiment and the second embodiment, by adjusting the shape and size of the valley and the crest provided on the outer peripheral surface of the lower valve, the syringe It deemed the discharged quantity thus blood backflow prevention effect of blood occurs with the extraction can be set appropriately.

Having thus described the embodiments of the present invention, the present invention is not to be construed as limiting the details of the illustrated embodiments, various changes based on the knowledge of those skilled in the art, modifications, improvements, etc. It can be implemented in an embodiment in which added.

For example, in this embodiment, since has upper valve 16 of the separate are superimposed, the respective slits 62, 74 are aligned in the circumferential direction are orthogonal to each other with respect to the lower valve 14 (94), for example, before withdrawing completely male luer 88 from the slit 74 of the upper valve 16, leakage by the slit 62 of the lower valve 14 (94) is a closed state, such liquid or blood of in operation of insertion and removal of the male luer 88 it is possible to more effectively prevent the out. However, it is not essential in the present invention that the perpendicular arrangement of the slits 74,62 of the upper valve 16 and lower valve 14 (94), also employing only lower valve 14 (94) without using the upper valve 16 it is also possible. Further, the upper valve 16 and lower valve 14 (94) may be integrated. The valve shape of the case, for example, may not be the shape matching the upper valve 16 and lower valve 14 of FIG. 1 may be a valve-shaped flange portion 64 is formed only on the lower portion of the valve. If thus the flange portion a valve shape is not provided in the valve intermediate portion, it is possible site for positioning the flange of the valve intermediate portion becomes unnecessary to reduce the diameter of the needle-less connector 10 (92) Center .

Further, in the above embodiment, the inclined surface shape of the projecting support surface 32 in the vertical cross section has been straight, as described above, in the present invention, the break point on the inclined surface of the projecting support surface 32 and flexing point is provided, the inclination angle may be different in part. At that time, the shape of the recess 66 of the lower valve 14 (94) is provided in correspondence with the shape of the projecting support surface 32, the inner peripheral surface of the projecting supporting surface 32 and the recess 66 are in close contact state thing is preferred, is not limited to this, for example, the inner peripheral surface of the projecting supporting surface 32 and the recess 66 may be slightly spaced apart. Furthermore, the shape of the top portion 34 is not limited to Nagayama shape, for example, it may be a circular shape or a polygonal shape.

Furthermore, in the above embodiment, the valleys 58 and ridges 60 but is provided on the valve body portion 54, not necessarily limited thereto, for example, troughs 58 and crests 60 are only the enlarged diameter portion 56 it may be provided. It is not necessary to form the enlarged diameter portion 56 in the lower valve 14 (94), for example as a base shape extending in the axial direction across the bottom valve 14 (94) at a constant peripheral surface shape irregularities on the outer peripheral surface subjected to it may be formed valley 58 and peak portions 60 appropriately. Moreover, valley 58 and ridge portions 60 need not be continuous over the entire circumference of the lower valve 14 (94), several partially applied in the circumferential direction on the outer peripheral surface of the lower valve 14 (94) There may be formed. Furthermore, the valleys 58 and ridges 60 may be spaced apart in the axial direction of the lower valve 14 (94).

Further, in the above embodiment, the deformation allowing space 78 of the elastic deformation of the lower valve 14 (94) is permitted is provided, not necessarily limited to the shape of the embodiment. Furthermore, the pressing sleeve 76 and the outer peripheral collar 40 is also not always necessary. Thus, for example, it may be a shape that spreads out the lower valve over the inner peripheral surface entire area formed by the base housing 18 and the cover body 44, in this case, the interior of the lower valve, the lower valve sealed deformable space permitting elastic deformation may be provided. For such a shape, the effect of the air spring is sufficiently exerted by the compressed air, at the time of restoration of the lower valve associated with the extraction of the male luer 88, also the action of the air spring as well as the elastic restoring force of the lower valve it is possible to obtain.

Further, the deformation allowing space 78 of the lower valve 14 (94) in the embodiment, the through-hole 80, the gap 82 may be filled with a synthetic foam or the like having a sponge-like open cell such as polyurethane. Such synthetic foam has a substantial space of internal open cells, excellent flexibility and elasticity, since it is retractable, upon insertion of the male luer 88, the lower valve by compression deformation 14 (94) to permit elastic deformation of the synthetic foam can also be made to change shape to match the shape after deformation of the lower valve 14 (94). Thus, instead of providing the space on the outer peripheral side or internal to a predetermined volume of the lower valve 14 (94), provided with a substantial space disposed a compressible member having elasticity, such as synthetic foam it may be.

Furthermore, in the embodiment, a pair of communicating grooves 37a on the projecting support surface 32, 37a and a pair of communicating grooves 37b, although 37b are provided, these communication grooves 37 is not necessarily required. Also, if the communication groove is formed, the number and direction of the communication groove that is formed, not the shape or the like to be limited any way. For example, 5 or more communicating grooves on the projecting support surface 32 may be formed, it may be curvilinear.

10,92: needleless connector, 12: housing, 14,94: the lower valve, 16: upper valve, 18: base housing, 20: cover housing, 28: chemical liquid flow path, 32: protruding support surface 34: top , 36: distal end opening portion, 52: air vent hole, 54: a valve body (thick portion), 56: expanded diameter portion (thin portion), 58: valley, 60: Yamabe, 62: slit, 64 and 70, , 72: flange portion, 78: deformation allowing space 80: through hole, 82: clearance, 88: male luer

Claims (12)

  1. Elastic valve body in a housing chemical liquid flow path is formed is built, male luer is connected to the chemical solution flow path when the male luer is placed inserted into the slit of the elastic valve body elastic valve body is opened in the needle-less connector to be,
    Wherein the housing is formed with a projecting support surface having an inclined surface of the flared, in the elastic valve body with respect to the projecting like support surfaces are superimposed in close contact, in projecting like support surface, the chemical together on the opening of the channel is the slit of the elastic valve body is brought into position,
    Needleless connectors, characterized in that the peaks and valleys extending irregularities attached to an outer peripheral surface of the elastic valve body superimposed on projecting like support surface in the circumferential direction is formed.
  2. Needleless connector according to claim 1, irregularities are smooth curved cross-sectional shape having no corner portion in the outer peripheral surface of the elastic valve body.
  3. The elastic valve body, and a thin portion that is superimposed on the skirt side region of said projecting support surface, and a thick portion that is superimposed on top side area of ​​the projecting like support surfaces are configured comprise,
    Needleless connector according to claim 1 or 2 on the outer peripheral surface of the upper end portion of the thick portion and the valley portion.
  4. The elastic valve body, and a thin portion that is superimposed on the skirt side region of said projecting support surface, and a thick portion that is superimposed on top side area of ​​the projecting like support surfaces are configured comprise,
    Needleless connector according to any one of claims 1 to 3, the troughs and the ridges are formed on the outer peripheral surface of at least the thick portion.
  5. The elastic valve body, and a thin portion that is superimposed on the skirt side region of said projecting support surface, and a thick portion that is superimposed on top side area of ​​the projecting like support surfaces are configured comprise,
    Needleless connectors according to the valley with any one of claims 1 to 4, wherein the ridges are formed on the outer peripheral surface of at least said thin portions.
  6. Needleless connector according to any one of claims 1 to 5, wherein the troughs and the ridges are provided along the entire outer peripheral surface of the elastic valve body.
  7. Together with the outer periphery of the elastic valve body is covered with the housing, it claims an inner space is provided between the them elastic valve body and the housing for permitting the deformation of the outer peripheral side of the elastic valve body 1 needle-less connector according to any one of 1-6.
  8. Needleless connector according to claim 7, the space communicating passage for communicating the interior space to the exterior space is formed.
  9. Wherein the elastic valve body, a pair of flange-like portions respectively extending outer peripheral side in both end portions of the penetrating direction of the slit are integrally formed,
    Needleless connector according to any one of claims 1 to 8, the outer peripheral edge portions of the pair of flange-like portion is fixed to and supported by each of the housing.
  10. Said and second valve body superimposed on the outer end surface of the elastic valve body is provided, slit the male luer provided at said second valve member is put cuttings are relative to the slit of the elastic valve body needleless connector according to any one of claims 1 to 9 are formed in the direction superimposed to intersect.
  11. Said projecting with at least the tip portion of the support surface is a Nagayama shape extending with a ridge-like top portion, the claims the slit of the elastic valve body are superimposed in a state extending along the top of 該稜 linear 1 needle-less connector according to any one of to 10.
  12. In the chemical liquid flow path, the protruding tip portion which is open to the top of the support surface, needleless connector according to any one of claims 1 to 11 in a nozzle-like narrowed down the cross-sectional area.
PCT/JP2013/076084 2012-09-26 2013-09-26 Needleless connector WO2014050976A1 (en)

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JP2012213139 2012-09-26

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016106957A (en) * 2014-12-09 2016-06-20 ニプロ株式会社 Needleless connector
WO2017141858A1 (en) * 2016-02-19 2017-08-24 株式会社ジェイ・エム・エス Adapter

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6050978A (en) * 1997-05-09 2000-04-18 Becton Dickinson And Company Needleless valve connector
WO2009133754A1 (en) * 2008-05-02 2009-11-05 テルモ株式会社 Connector assembly
JP2010508986A (en) * 2006-11-02 2010-03-25 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company Chamber ventilation of the vascular access device
JP2010514528A (en) * 2007-01-03 2010-05-06 ヴィゴンVygon Connector for particular to establish a valve control fluid communication for the medical field

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ286445A (en) * 1995-05-16 1997-12-19 Ivac Corp Needleless luer connector: deformable piston occludes bore
US8758306B2 (en) * 2010-05-17 2014-06-24 Icu Medical, Inc. Medical connectors and methods of use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6050978A (en) * 1997-05-09 2000-04-18 Becton Dickinson And Company Needleless valve connector
JP2010508986A (en) * 2006-11-02 2010-03-25 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company Chamber ventilation of the vascular access device
JP2010514528A (en) * 2007-01-03 2010-05-06 ヴィゴンVygon Connector for particular to establish a valve control fluid communication for the medical field
WO2009133754A1 (en) * 2008-05-02 2009-11-05 テルモ株式会社 Connector assembly

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016106957A (en) * 2014-12-09 2016-06-20 ニプロ株式会社 Needleless connector
WO2017141858A1 (en) * 2016-02-19 2017-08-24 株式会社ジェイ・エム・エス Adapter

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JP6311934B2 (en) 2018-04-18
JPWO2014050976A1 (en) 2016-08-22

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