WO2014045450A1

WO2014045450A1 - Measurement system

Info

Publication number: WO2014045450A1
Application number: PCT/JP2012/074445
Authority: WO
Inventors: 虎井裕; 望月智則
Original assignee: テルモ株式会社
Priority date: 2012-09-24
Filing date: 2012-09-24
Publication date: 2014-03-27

Abstract

A measurement system (10) is provided with: a plurality of measurement devices (12, 14) for measuring a plurality of different vital signs of a subject; a discrimination unit (44a) for determining, on the basis of a plurality of measurement values which are the measurement results of the plurality of measurement devices (12, 14), the presence of a hypoglycemic state of the subject; and a warning unit (44b) which, in cases when the discrimination unit (44a) has determined there to be a hypoglycemic state, issues a warning to the subject. As a result, a subject can more accurately recognize the presence of a hypoglycemic state, and can take appropriate measure.

Description

Measuring system

The present invention relates to a measurement system that measures a blood glucose level of a subject and notifies a hypoglycemic state.

In the treatment of diabetes, it is important to control blood sugar to improve hyperglycemia and bring the blood sugar level as close to normal as possible. If this blood sugar control is not successful, hypoglycemia is caused. In hypoglycemia, initial symptoms such as rapid heartbeat, cold sweat, and trembling of the hands appear, and if the blood glucose level is lowered further, disturbance of consciousness (coma) occurs. Accordingly, a diabetic patient must accurately grasp the occurrence of initial symptoms and take appropriate measures such as ingesting sugar when the symptoms occur.

Diabetic patients are usually able to cope with hypoglycemia as an early symptom, but patients who have been taking insulin therapy for a long time, patients with autonomic disorder, elderly patients etc. Unconsciousness may cause sudden consciousness disturbance (unconscious hypoglycemia).

In order to prevent such unconscious hypoglycemia, Japanese Patent Application Laid-Open No. 2008-79993 discloses blood glucose measurement using a continuous blood glucose monitor (Continuous Glucose Monitoring: CGM) that continuously monitors a subject's blood sugar level. An apparatus is described that issues a warning when a blood sugar level reaches a first risk level and notifies a third party when the blood sugar level reaches a second risk level.

Japanese Patent Application Laid-Open No. 2008-79994 discloses a blood glucose measurement device using a continuous blood glucose monitor that continuously monitors a subject's blood glucose level, wherein When the difference from the blood glucose level measured this time is greater than or equal to the caution blood glucose change value, an alarm is issued if the blood glucose level measured this time is not less than or equal to the risk level blood glucose level, and if it is less than or equal to the risk level blood glucose level, a third party is notified. It is described to do.

However, the hypoglycemia state cannot be accurately grasped only by monitoring the blood glucose level, for example, the level of the blood glucose level causing hypoglycemia varies among individuals.

The present invention has been made in view of such conventional problems, and an object of the present invention is to provide a measurement system for more accurately grasping and notifying a hypoglycemic state.

In order to achieve the above object, the present invention provides a measurement system, a plurality of measurement devices that measure a plurality of vital signs of different subjects, and a plurality of measurement values that are measurement results of the plurality of measurement devices. And a warning unit that warns the subject when the determination unit determines that the subject is in a hypoglycemic state. To do.

According to the above configuration, the subject can more accurately recognize that the subject is in a blood glucose state and can take an appropriate treatment.

In the measurement system, the hypoglycemic state includes a plurality of hypoglycemic levels, and the determination unit is configured for each vital sign based on the plurality of measurement values that are measurement results of the plurality of measurement devices. It is determined whether or not hypoglycemia, respectively, according to the number and type of the measured value of the vital sign determined to be hypoglycemia, to determine the subject's hypoglycemia level, the warning unit, According to the low blood glucose level determined by the determination unit, warning is performed by changing the alarm level.

According to the above configuration, the subject can recognize a low blood glucose level.

In the measurement system, the warning unit outputs a warning sound at a volume corresponding to the low blood glucose level determined by the determination unit.

According to the above configuration, the subject can easily and intuitively recognize the low blood glucose level.

In the measurement system, a threshold value is set for each of the plurality of vital signs, and the determination unit compares the measured value, which is a measurement result of the measuring device, with the threshold value, thereby obtaining the vital sign. It is characterized by each determining whether it is hypoglycemia every time.

According to the above configuration, the determination unit can easily and accurately determine whether or not there is hypoglycemia based on each measurement value.

In the measurement system, the plurality of vital signs include blood glucose, and the determination unit compares the blood glucose level that is the measurement value or a change amount of the blood glucose level with the threshold value, and the blood glucose level or the When the amount of change in blood glucose level is less than or equal to the threshold, it is determined that the blood glucose level is low.

According to the above configuration, it is possible to accurately determine whether or not the blood glucose level is hypoglycemia. For example, not only when the blood glucose level is equal to or lower than the threshold value, but also when the amount of change in the blood glucose level is equal to or lower than the threshold value, the blood glucose level is rapidly decreased. it can.

In the measurement system, when the determination unit determines that hypoglycemia is based on the blood glucose level, the determination unit raises the low blood glucose level higher than when it is not determined to be hypoglycemia based on the blood glucose level. And

According to the above configuration, the hypoglycemia level can be determined with emphasis on the blood glucose level that directly indicates whether or not hypoglycemia, and the hypoglycemia level can be accurately determined.

In the measurement system, the plurality of vital signs include pulsation, sweating, or hand tremor of the subject, and the determination unit includes a heart rate, a sweating amount, or a hand as the measurement value. The frequency of tremors is compared with the threshold, and if the heart rate, the amount of sweating, or the frequency is equal to or higher than the threshold, it is determined that the blood glucose is low.

According to the above configuration, it is possible to accurately determine whether the blood glucose level is low even with vital signs other than blood glucose.

In the measurement system, the determination unit determines whether or not the blood glucose level is low for each vital sign based on the plurality of measurement values that are measurement results of the plurality of measurement devices, and the blood glucose level is low. When the number of the measured values of the vital sign determined to be equal to or greater than a certain number, it is determined that the subject is in a hypoglycemic state.

According to the above configuration, when it can be reliably determined that the subject is hypoglycemic, it can be determined that the subject is hypoglycemic, and the subject is more hypoglycemic. It can be recognized accurately.

According to the present invention, when measuring a plurality of vital signs different for a subject, determining a hypoglycemic state of the subject based on a plurality of measured values as measurement results, and determining a hypoglycemic state, Since the warning is given to the subject, the subject can more accurately recognize that the subject is in a blood glucose state and can take appropriate measures.

It is a block diagram of the measurement system concerning an embodiment. It is a flowchart which shows operation | movement of the blood glucose measurement apparatus of the measurement system shown in FIG. It is a flowchart which shows operation | movement of the vital sign measuring apparatus of the measuring system shown in FIG. It is a flowchart which shows operation | movement of the display apparatus when the blood glucose level or the variation | change_quantity of a blood glucose level is received. It is a flowchart which shows operation | movement of the display apparatus when the amount of perspiration is received. It is a figure showing the hypoglycemia level discriminate | determined based on the hypoglycemia determination by a blood glucose level and the hypoglycemia determination by one vital sign other than a blood glucose level.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS A measurement system according to the present invention will be described in detail below with reference to preferred embodiments and referring to the accompanying drawings.

FIG. 1 is a block diagram of a measurement system 10 according to an embodiment. The measurement system 10 includes a blood glucose measurement device 12 that measures blood sugar, which is a type of vital sign of the subject, and a plurality of vital signs different from the subject other than the blood glucose level (for example, pulsation, sweating, hand tremor, etc.) A plurality of vital sign measuring devices 14 and a display device 16. The reason for measuring pulsation, sweating of hands or feet, trembling of hands, etc. is usually that when the subject becomes hypoglycemic, the pulsation is faster, cold sweat is applied, and the hand shakes. So measure these vital signs.

The blood glucose measurement device 12 includes a measurement unit 20, a control unit 22, and a communication unit 24. The measuring unit 20 is provided with a needle 20a for puncturing the subject's skin and placing it under the skin. The needle 20a is a capillary that guides the blood to reach the measurement unit 20.

The measuring unit 20 measures the concentration of glucose contained in the blood sent from the needle 20a. Although not shown, the measurement unit 30 includes a light receiving element such as a photodiode, a light emitting element such as a light emitting diode, and an indicator layer. The indicator layer contains a fluorescent dye as a labeling compound, and the labeling compound captures glucose introduced by the needle 20a. When the light emitting element is caused to emit light and light is incident on the indicator, the indicator layer obtains fluorescence having an intensity corresponding to the glucose concentration. The fluorescence from the indicator layer is photoelectrically converted by the light receiving element, and a light receiving signal (light receiving signal indicating the glucose concentration) is sent to the control unit 22.

The control unit 22 has a CPU and a memory (not shown), and controls the blood glucose measurement device 12 as a whole. The control unit 22 converts the light reception signal sent from the measurement unit 20 into a digital signal, and calculates a glucose concentration value (hereinafter referred to as a blood glucose level) based on the converted light reception signal. The control unit 22 outputs the calculated blood glucose level (measurement value) that is a measurement result to the communication unit 24. The measurement unit 20 obtains a light reception signal indicating the glucose concentration at a constant cycle and outputs the received light signal to the control unit 22. Therefore, the control unit 22 performs blood glucose level at the constant cycle (a constant measurement cycle). Is calculated.

The communication unit 24 wirelessly communicates with the display device 16 to transmit the blood glucose level transmitted from the control unit 22 to the display device 16 by wireless communication. The communication unit 24 performs wireless communication using Bluetooth, IrDA (Infrared Data Association), or the like.

The vital sign measurement device 14 includes a measurement unit 30, a control unit 32, and a communication unit 34. The measuring unit 30 measures the heart rate of the subject, the sweating amount of the hand or foot, the vibration frequency of hand tremors, and the like. If the measurement unit 30 is for measuring a heart rate, the measurement unit 30 has an electrode for detecting an electrocardiogram signal, and if the measurement unit 30 measures the sweating amount of a hand or a foot, It has electrodes and detects the capacitance of the subject's skin. Moreover, when the measurement part 30 measures the vibration frequency of a hand tremor, the measurement part 30 has a gyro sensor which detects an angular velocity.

The control unit 32 includes a CPU and a memory (not shown), and controls the vital sign measurement device 14 as a whole. The control unit 32 converts the signal sent from the measurement unit 30 into a digital signal, and calculates the heart rate, the amount of sweating, or the vibration frequency of hand tremor based on the converted digital signal.

For example, when an electrocardiogram signal is sent from the measurement unit 30, the heart rate is calculated based on the electrocardiogram signal converted into a digital signal. Further, when a signal (capacitance signal) indicating the capacitance of the subject's skin is sent from the measurement unit 30, the amount of sweating is calculated based on the capacitance signal converted into a digital signal. . Further, the vibration frequency is calculated from the angular velocity signal detected by the gyro sensor from the measurement unit 30. The control unit 32 outputs the calculated measurement value (heart rate, sweating amount, or vibration frequency), which is a measurement result, to the communication unit 34. Note that the measurement unit 30 obtains an electrocardiogram signal, an electrostatic capacity signal, an angular velocity signal, or the like at the fixed cycle and outputs the signal to the control unit 32. In the measurement cycle), the heart rate, the sweating amount of the hand or foot, and the vibration frequency of the hand tremor are calculated.

The communication unit 34 wirelessly communicates with the display device 16 to transmit the measurement value transmitted from the control unit 32 to the display device 16 by wireless communication. The communication unit 34 performs wireless communication using Bluetooth, IrDA (Infrared Data Association), or the like.

Here, by shifting the measurement timing of the blood glucose measurement device 12 and the measurement timings of the plurality of vital sign measurement devices 14, a vital sign indicating whether or not the blood glucose is low at intervals shorter than the measurement cycle of the blood glucose measurement device 12. Can be measured. Since the blood glucose measurement device 12 and the plurality of vital sign measurement devices 14 are not synchronized, the measurement timings of the blood glucose measurement device 12 and the plurality of vital sign measurement devices 14 are naturally shifted. In addition, the blood glucose measurement device 12 and the plurality of vital sign measurement devices 14 may perform the synchronization process to arbitrarily shift the measurement timing.

The display device 16 includes a communication unit 40, a storage unit 42, a control unit 44, a sound output unit 46, a display unit 48, and an operation unit 50. The communication unit 40 wirelessly communicates with the blood glucose measurement device 12 and the plurality of vital sign measurement devices 14 to acquire measurement values such as blood glucose level, heart rate, sweating amount, and vibration frequency. Specifically, the measurement value is acquired by wirelessly communicating with the communication unit 24 of the blood glucose measurement device 12 and the communication unit 34 of the plurality of vital sign measurement devices 14.

The storage unit 42 stores a threshold value set for each vital sign (blood sugar, pulsation, cold sweat, hand tremor) measured by the blood glucose measurement device 12 and the vital sign measurement device 14. In other words, the storage unit 42 stores threshold values corresponding to blood sugar level, heart rate, sweating amount, hand tremor frequency, and the like. The storage unit 42 includes a plurality of storage areas for storing vital sign flags such as a blood glucose level flag, a heart rate flag, a sweating amount flag, and a vibration frequency flag.

The control unit 44 includes a CPU and a memory (not shown) and controls the entire display device 16. The control unit 44 includes a determination unit 44a, and the determination unit 44a determines the hypoglycemia state of the subject based on the measured values such as blood glucose level, heart rate, and sweating amount received by the communication unit 40. This hypoglycemic state has a plurality of hypoglycemic levels, and the determination unit 44a determines the hypoglycemic level of the subject using the received measured value of the vital sign and its type and threshold. The higher the hypoglycemia level, the higher the possibility that the subject is in a hypoglycemic state, and the lower the hypoglycemic level, the lower the possibility that the subject is in the hypoglycemic state.

Further, the control unit 44 includes a warning unit 44b, and the warning unit 44b outputs a warning sound from the sound output unit 46 such as a speaker at a volume corresponding to the low blood glucose level determined by the determination unit 44a. Alert the subject that they are hypoglycemic. Specifically, when the low blood glucose level is low, a warning sound is output at a low volume, and when the low blood glucose level is high, a warning sound is output at a high volume.

The warning unit 44b warns the subject that the blood glucose level is low by displaying a warning on the display unit 48 such as a liquid crystal display in a display mode according to the low blood glucose level determined by the determination unit 44a. . Specifically, if the hypoglycemia level is low, that fact is displayed (for example, a character such as “There is a possibility of hypoglycemia” is displayed), and if the hypoglycemia level is high, that fact is displayed (for example, , “Likely hypoglycemic state is likely to be displayed.” The warning unit 44b may change the brightness and color of the backlight of the display unit 48 according to the low blood sugar level. In short, the warning unit 44b may change the alarm level and issue a warning according to the low blood glucose level determined by the determination unit 44a.

As described above, the display unit 48 displays a blood glucose level measured by the blood glucose measurement device 12 and functions as a graphical user interface (GUI) in addition to displaying a warning. The operation unit 50 is for the subject to perform various operations such as switching display contents of the display unit 48 and inputting predetermined information.

Next, the operation of the measurement system 10 will be described. In the description of the operation of the measurement system 10, for the sake of simplicity, it is assumed that there is one vital sign measuring device 14 and the vital sign measuring device 14 measures the amount of sweating.

First, the operation of the blood glucose measurement device 12 of the measurement system 10 will be described with reference to the flowchart of FIG. The control unit 22 determines whether or not the measurement timing has arrived (step S1). This measurement timing arrives at a constant measurement cycle. If it is determined in step S1 that the measurement timing has not arrived, it remains in step S1 until it arrives. If it is determined that the measurement timing has arrived, the control unit 22 controls the measurement unit 20 so that the measurement unit 20 A light reception signal indicating the concentration of glucose is acquired (step S2).

Next, the control unit 22 calculates a blood glucose level based on the acquired light reception signal (step S3). In addition, the control part 22 may calculate the variation | change_quantity of a blood glucose level based on the blood glucose level calculated this time and the blood glucose level calculated for the fixed time ago. This amount of change can be obtained by subtracting the blood glucose level calculated a certain time ago from the blood glucose level calculated this time. Therefore, when the blood glucose level tends to decrease, the amount of change becomes a negative value.

Next, the communication unit 24 transmits the blood glucose level calculated in step S3 to the display device 16 (step S4), and returns to step S1. If the change amount of the blood glucose level is calculated in step S3, the change amount of the blood glucose level may be transmitted to the display device 16.

Next, the operation of the vital sign measurement device 14 of the measurement system 10 will be described with reference to the flowchart of FIG. The control unit 32 determines whether or not the measurement timing has arrived (step S11). This measurement timing arrives at a constant measurement cycle. If it is determined in step S11 that the measurement timing has not arrived, the process stays in step S11 until it arrives. If it is determined that the measurement timing has arrived, the control unit 32 controls the measurement unit 30 so that the measurement unit 30 A skin capacitance signal is acquired (step S12).

Next, the control unit 32 calculates the amount of sweating based on the acquired capacitance signal (step S13). Next, the communication unit 34 transmits the sweating amount calculated in step S13 to the display device 16 (step S14), and returns to step S11.

Next, the operation of the display device 16 of the measurement system 10 will be described with reference to the flowcharts of FIGS. First, the operation of the display device 16 when a blood glucose level or a change amount of the blood glucose level is received will be described according to the flowchart of FIG. 4, and then the operation of the display device 16 when the perspiration amount is received will be described according to the flowchart of FIG. .

When the communication unit 40 receives the blood glucose level from the blood glucose measurement device 12, the determination unit 44a of the control unit 44 makes a hypoglycemia determination based on the blood glucose level (step S21 in FIG. 4). Specifically, the determination unit 44a compares the received blood glucose level with the threshold value of the blood glucose level stored in the storage unit 42, determines that the received blood glucose level is equal to or lower than the threshold, and determines that the blood glucose level is low. If the blood glucose level is greater than the threshold value, it is determined that the blood glucose level is not low.

When the blood glucose level change amount is received, the determination unit 44a receives the blood glucose level change amount and the received blood glucose level change amount and the blood glucose level change stored in the storage unit 42. When the received change amount of the blood sugar level is equal to or less than the threshold value, it is determined that the blood glucose level is lower than the threshold value. This is because when the amount of change in blood glucose level is equal to or lower than the threshold, it is desirable to determine that the blood glucose level has dropped sharply and hypoglycemia.

When it is determined in step S21 that the blood glucose level is low, the determination unit 44a sets a blood glucose level flag (step S22). That is, the blood glucose level flag is set by storing “1” in the storage area for storing the blood glucose level flag in the storage unit 42. If the blood sugar level flag has already been set, the operation of step S22 is not performed.

Next, the determination unit 44a determines whether or not the sweating amount flag is set (step S23). That is, it is determined whether or not “1” is stored in the storage area for storing the sweating amount flag in the storage unit 42. As will be described in detail later, the determination unit 44a sets a perspiration amount flag when it is determined that hypoglycemia is determined by hypoglycemia based on the perspiration amount.

If it is determined in step S23 that the sweating amount flag is set, the determination unit 44a determines that the hypoglycemic state of the subject is the low blood glucose level 3 (step S24), and the warning unit 44b of the control unit 44 Warns at an alarm level corresponding to the low blood glucose level 3 (step S25), and ends the operation. For example, a warning sound is output from the sound output unit 46 at the volume 3, and a warning such as “it is a hypoglycemic state” is displayed on the display unit 48.

On the other hand, if it is determined in step S23 that the sweating amount flag is not set, the determination unit 44a determines that the hypoglycemic state of the subject is the low blood glucose level 2 (step S26), and the warning unit 44b is low. A warning is given at an alarm level corresponding to blood glucose level 2 (step S27), and the operation is terminated. For example, a warning sound is output from the sound output unit 46 at a volume 2 smaller than the volume 3, and a warning is displayed by displaying characters such as “There is a high possibility of a hypoglycemic state. Do.

If it is determined in step S21 that the blood glucose level is not low, the determination unit 44a clears the blood glucose level flag (step S28). That is, the blood sugar level flag is cleared by storing “0” in the storage area for storing the blood sugar level flag in the storage unit 42. If the blood sugar level flag has already been cleared, the operation of step S28 is not performed.

Next, the determination unit 44a determines whether or not the sweating amount flag is set (step S29). If it is determined in step S29 that the sweating amount flag is not set, the operation is terminated. If it is determined in step S29 that the sweating amount flag is set, the determination unit 44a determines that the subject's hypoglycemic state is low. It is determined that the blood glucose level is 1 (step S30), and the warning unit 44b warns at an alarm level corresponding to the low blood glucose level 1 (step S31) and ends the operation. For example, a warning sound is output from the sound output unit 46 at a volume 1 lower than the volume 2, and a warning such as “There is a possibility of hypoglycemia” is displayed on the display unit 48.

Further, when the communication unit 40 receives the sweating amount from the vital sign measurement device 14, the determination unit 44a makes a hypoglycemic determination based on the sweating amount (step S51 in FIG. 5). Specifically, the determination unit 44a compares the received amount of sweating with a threshold value of the sweating amount stored in the storage unit 42, determines that the received sweating amount is equal to or higher than the threshold value, and determines that the blood glucose level is low. If the perspiration amount is less than the threshold, it is determined that the blood sugar is not hypoglycemic.

If it is determined in step S51 that the blood sugar level is low, the determination unit 44a sets a sweating amount flag (step S52). That is, by storing “1” in the storage area for storing the sweating amount flag of the storage unit 42, the sweating amount flag is set. When the sweating amount flag is already set, the operation of step S52 is not performed.

Next, the determination unit 44a determines whether or not the blood sugar level flag is set (step S53). That is, it is determined whether or not “1” is stored in the storage area for storing the blood sugar level flag in the storage unit 42.

If it is determined in step S53 that the blood glucose level flag is set, the determination unit 44a determines that the hypoglycemic state of the subject is the low blood glucose level 3 (step S54), and the warning unit 44b A warning is given at an alarm level corresponding to level 3 (step S55), and the operation is terminated.

On the other hand, if it is determined in step S53 that the blood glucose level flag is not set, the determination unit 44a determines that the subject's hypoglycemia state is low blood glucose level 1 (step S56), and the warning unit 44b A warning is given at an alarm level corresponding to the low blood glucose level 1 (step S57), and the operation is terminated.

If it is determined in step S51 that the blood glucose level is not low, the determination unit 44a clears the sweating amount flag (step S58). That is, by storing “0” in the storage area for storing the sweating amount flag in the storage unit 42, the sweating amount flag is cleared. If the sweating amount flag has already been cleared, the operation of step S58 is not performed.

Next, the determination unit 44a determines whether or not the blood sugar level flag is set (step S59). If it is determined in step S59 that the blood glucose level flag is not set, the operation is terminated. If it is determined in step S59 that the blood glucose level flag is set, the determination unit 44a determines that the subject has a low hypoglycemic state. It is determined that the blood sugar level is 2 (step S60), and the warning unit 44b warns at an alarm level corresponding to the low blood sugar level 2 (step S61) and ends the operation.

FIG. 6 is a diagram showing the hypoglycemia level determined based on the hypoglycemia determination based on the blood glucose level and the hypoglycemia determination based on one vital sign other than the blood glucose level, as shown in FIGS. 4 and 5.

If it is determined to be positive (hypoglycemia) by hypoglycemia determination based on blood glucose level, and if it is determined to be positive (hypoglycemia) by hypoglycemia determination based on vital signs other than blood glucose level (sweat amount in FIGS. 4 and 5), It is determined that the hypoglycemia state is hypoglycemia level 3. Further, if the determination is affirmative based on the hypoglycemia determination based on the blood glucose level and the determination is negative (not hypoglycemia) based on the hypoglycemia determination based on a vital sign other than the blood glucose level, it is determined that the hypoglycemia state is the low blood glucose level 2. Further, if the determination is negative based on the hypoglycemia determination based on the blood glucose level and the determination is affirmative based on the hypoglycemia determination based on a vital sign other than the blood glucose level, it is determined that the hypoglycemia state is the low blood glucose level 1.

Thus, the hypoglycemia level is determined according to the number of measured values determined to be hypoglycemia and the type thereof (blood glucose level, heart rate, sweat rate, hand tremor frequency). Note that the determination unit 44a determines that the hypoglycemia is determined based on the hypoglycemia based on the blood glucose level, and determines that the hypoglycemia state is not determined if the determination is based on the hypoglycemia determination based on vital signs other than the blood glucose level.

As described above, when the hypoglycemic state of the subject is determined based on the measured values of a plurality of vital signs (blood glucose level, heart rate, sweat rate, hand tremor frequency), and the hypoglycemic state is determined. Warns the subject so that the subject can more accurately recognize that the subject is in a hypoglycemic state. In other words, since vital signs other than blood glucose level are also measured, even if it is not determined that the blood glucose level is a hypoglycemic state alone, it is determined from the measured values of vital signs other than the blood glucose level that the blood sugar level is low. It becomes possible to do.

Based on the measurement values obtained by measuring multiple vital signs, it is determined whether or not there is hypoglycemia for each vital sign, and the number and types of vital sign measurements determined to be hypoglycemia Accordingly, the hypoglycemia level is discriminated, and the alarm level is changed according to the discriminated hypoglycemia level to give a warning, so that the subject can recognize the level of the hypoglycemia state.

Also, since the warning sound is output at a volume corresponding to the low blood sugar level, the low blood sugar level can be easily and intuitively recognized.

A threshold is set for each vital sign, and by comparing the measured value with the threshold, it is determined whether the blood glucose is hypoglycemic for each vital sign. It can be performed easily and accurately.

Vital signs include blood sugar, compare blood sugar level or amount of change of blood sugar with a threshold value, and if blood sugar level or amount of change of blood sugar level is less than or equal to threshold value, it is determined that the blood sugar level is low. Hypoglycemia can be determined with high accuracy.

If the hypoglycemia is determined based on the blood glucose level, the hypoglycemia level is set higher than if the hypoglycemia is not determined based on the blood glucose level, so focus on the blood glucose level that directly indicates whether or not the hypoglycemia is present. Thus, the hypoglycemia level can be determined, and the hypoglycemia level can be accurately determined.

Vital signs include the subject's pulsation, sweating, or hand tremor, comparing the measured heart rate, sweating amount, or hand tremor vibration frequency with a threshold value, heart rate, sweating amount, Alternatively, when the frequency is equal to or higher than the threshold value, it is determined that the blood glucose is low, so it is possible to accurately determine whether the blood glucose is low even with vital signs other than the blood glucose level.

The determination unit 44a determines that the subject is hypoglycemic based on the hypoglycemia determination based on the blood glucose level, and determines that the subject is hypoglycemic based on the hypoglycemia determination based on the vital sign other than the blood glucose level. It may be determined that the blood glucose level is low, and the warning unit 44b may output a warning sound. In addition, the number of measured values of vital signs determined to be hypoglycemia (number of measured values of blood glucose level, heart rate, sweat rate, etc.) based on the hypoglycemia determination by a plurality of vital signs exceeds a certain number In this case, it may be determined that the subject is in a hypoglycemic state. As a result, when the subject can be surely determined to have hypoglycemia, the subject can be determined to be in a hypoglycemic state, and the subject can more accurately recognize that the subject is in a hypoglycemic state. can do. In addition, even if the number of vital sign measurements determined to be hypoglycemia is greater than a certain number, the vital sign measurement values determined to be hypoglycemia do not include blood sugar levels In such a case (when the hypoglycemia is not determined by the hypoglycemia determination based on the blood glucose level), it is not necessary to determine that the subject is in a hypoglycemic state.

As mentioned above, although this invention was demonstrated using suitable embodiment, the technical scope of this invention is not limited to the range as described in the said embodiment. It will be apparent to those skilled in the art that various modifications or improvements can be added to the above embodiment. It is apparent from the description of the scope of claims that embodiments with such changes or improvements can be included in the technical scope of the present invention.

Claims

A plurality of measuring devices (12, 14) for measuring a plurality of vital signs of different subjects;
A determination unit (44a) for determining a hypoglycemia state of the subject based on a plurality of measurement values which are measurement results of the plurality of measurement devices (12, 14);
When the discrimination unit (44a) discriminates a hypoglycemic state, a warning unit (44b) that warns the subject,
A measurement system (10) comprising:
A measurement system (10) according to claim 1, comprising:
The hypoglycemic state comprises a plurality of hypoglycemic levels;
The determination unit (44a) determines whether or not the blood glucose level is low for each vital sign based on the plurality of measurement values that are measurement results of the plurality of measurement devices (12, 14). According to the number and type of the measured value of the vital sign determined to be, determine the hypoglycemia level of the subject,
The measurement unit (10), wherein the warning unit (44b) changes the alarm level according to the hypoglycemia level determined by the determination unit (44a).
A measurement system (10) according to claim 2, comprising:
The measurement system (10), wherein the warning unit (44b) outputs a warning sound at a volume corresponding to the low blood glucose level determined by the determination unit (44a).
A measurement system (10) according to claim 2, comprising:
A threshold is set for each of the plurality of vital signs,
The discriminating unit (44a) compares the measured value, which is the measurement result of the measuring device (12, 14), with the threshold value, thereby determining whether or not the blood glucose level is low for each vital sign. Characteristic measuring system (10).
A measurement system (10) according to claim 4,
The plurality of vital signs includes blood sugar,
The determination unit (44a) compares the blood glucose level that is the measurement value or the amount of change in the blood glucose level with the threshold, and if the blood glucose level or the amount of change in the blood glucose level is less than or equal to the threshold, A measurement system (10) characterized by determining that
A measurement system (10) according to claim 5,
The determination unit (44a) increases the low blood glucose level when it is determined that the blood glucose level is low, based on the blood glucose level, compared to when it is not determined that the blood glucose level is low. (10).
A measurement system (10) according to claim 4,
The plurality of vital signs include pulsation, sweating, or trembling of the subject,
The determination unit (44a) compares the measured heart rate, the amount of sweating, or the vibration frequency of hand tremor with the threshold value, and the heart rate, the sweating amount, or the vibration frequency is the threshold value. In the above case, the measurement system (10) is characterized by determining that the blood glucose is low.
A measurement system (10) according to claim 1, comprising:
The determination unit (44a) determines whether or not the blood glucose level is low for each vital sign based on the plurality of measurement values that are measurement results of the plurality of measurement devices (12, 14). The measurement system (10), wherein the subject is determined to be in a hypoglycemic state when the number of the measured values of the vital sign determined to be equal to or greater than a certain number.