WO2014033751A3 - Pharmaceutical composition of propofol - Google Patents

Pharmaceutical composition of propofol Download PDF

Info

Publication number
WO2014033751A3
WO2014033751A3 PCT/IN2013/000495 IN2013000495W WO2014033751A3 WO 2014033751 A3 WO2014033751 A3 WO 2014033751A3 IN 2013000495 W IN2013000495 W IN 2013000495W WO 2014033751 A3 WO2014033751 A3 WO 2014033751A3
Authority
WO
WIPO (PCT)
Prior art keywords
propofol
pharmaceutical composition
avoiding
relates
present
Prior art date
Application number
PCT/IN2013/000495
Other languages
French (fr)
Other versions
WO2014033751A2 (en
Inventor
Sougata Pramanick
Mukund Keshav Gurjar
Samit Satish Mehta
Original Assignee
Emcure Pharmaceuticals Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emcure Pharmaceuticals Limited filed Critical Emcure Pharmaceuticals Limited
Priority to EP13833549.2A priority Critical patent/EP2884964A4/en
Publication of WO2014033751A2 publication Critical patent/WO2014033751A2/en
Publication of WO2014033751A3 publication Critical patent/WO2014033751A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to a stable injectable emulsion formulation of Propofol having uniform droplet size, which is obtained at a pH above 8.5 and by avoiding a rotary sterilizer.
PCT/IN2013/000495 2012-08-16 2013-08-13 Pharmaceutical composition of propofol WO2014033751A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP13833549.2A EP2884964A4 (en) 2012-08-16 2013-08-13 Pharmaceutical composition of propofol

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2373/MUM/2012 2012-08-16
IN2373MU2012 2012-08-16

Publications (2)

Publication Number Publication Date
WO2014033751A2 WO2014033751A2 (en) 2014-03-06
WO2014033751A3 true WO2014033751A3 (en) 2014-05-30

Family

ID=50184537

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2013/000495 WO2014033751A2 (en) 2012-08-16 2013-08-13 Pharmaceutical composition of propofol

Country Status (2)

Country Link
EP (1) EP2884964A4 (en)
WO (1) WO2014033751A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104490780B (en) * 2015-01-16 2017-04-19 河北一品制药有限公司 Preparation method of propofol fat emulsion injection

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000056364A1 (en) * 1999-03-24 2000-09-28 American Home Products Corporation Propofol formulation containing tris
CN1430503A (en) * 2000-05-25 2003-07-16 阿斯特拉曾尼卡有限公司 O/W emulsion
CN101553215A (en) * 2006-10-27 2009-10-07 克里斯泰利亚化学药物产品有限公司 Stable and ready-to-use oil-in-water propofol microemulsion
DE102009003980A1 (en) * 2009-01-07 2010-07-08 B. Braun Melsungen Ag Formulation, useful for preventing propofol infusion syndrome, comprises propofol and a fatty emulsion with a triglyceride
CN102552136A (en) * 2012-02-09 2012-07-11 清远嘉博制药有限公司 Propofol medium/long-chain injection and preparation method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6028108A (en) * 1998-10-22 2000-02-22 America Home Products Corporation Propofol composition comprising pentetate
KR100459025B1 (en) * 2002-05-02 2004-12-03 (주) 에프디엘 Novel composition comprising propofol for the use of injection
AU2006310113A1 (en) * 2005-08-05 2007-05-10 Bharat Serums & Vaccines Ltd. Intravenous propofol emulsion compositions having preservative efficacy
US9132090B2 (en) * 2009-01-13 2015-09-15 Chetan Majmudar Propofol based anesthetic with preservative

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000056364A1 (en) * 1999-03-24 2000-09-28 American Home Products Corporation Propofol formulation containing tris
CN1430503A (en) * 2000-05-25 2003-07-16 阿斯特拉曾尼卡有限公司 O/W emulsion
CN101553215A (en) * 2006-10-27 2009-10-07 克里斯泰利亚化学药物产品有限公司 Stable and ready-to-use oil-in-water propofol microemulsion
DE102009003980A1 (en) * 2009-01-07 2010-07-08 B. Braun Melsungen Ag Formulation, useful for preventing propofol infusion syndrome, comprises propofol and a fatty emulsion with a triglyceride
CN102552136A (en) * 2012-02-09 2012-07-11 清远嘉博制药有限公司 Propofol medium/long-chain injection and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2884964A4 *

Also Published As

Publication number Publication date
WO2014033751A2 (en) 2014-03-06
EP2884964A2 (en) 2015-06-24
EP2884964A4 (en) 2016-01-06

Similar Documents

Publication Publication Date Title
WO2014023640A3 (en) Cosmetic compositions
BR112014017749A8 (en) 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF
WO2012042371A3 (en) Pharmaceutical composition
BR112015000229A2 (en) stable aqueous formulations of etanercept
PH12014501967A1 (en) Benzodioxanes in combination with other actives for inhibiting leukotriene production
WO2014121040A8 (en) Flap modulators
EP3279207A4 (en) Novel compound of 4'-thionucleoside, as well as preparation method therefor, pharmaceutical composition thereof and application thereof
EP3034082A4 (en) Pharmaceutical composition for treating or preventing neuropsychitric disease, containing flavone-6-c-glucose derivatives as active ingredients
WO2012037562A3 (en) Pharmaceutical and nutraceutical compositions of abscisic acid
WO2013134534A3 (en) Solid state forms of cabazitaxel and processes for preparation thereof
EA201200616A1 (en) DERIVATIVES 2-OXO-1-PIRROLIDININILIMIDAZOTHIAADIA ASOL
WO2012137227A3 (en) Solid forms of antiretroviral compounds and anti-oxidative acids, processes for preparation and pharmaceutical compositions thereof
EP4327880A3 (en) Solid state form of ribociclib succinate
MX2014010433A (en) Novel crystalline form of sitagliptin sulfate.
UA116889C2 (en) COMPOSITION COMPRISING A MIXTURE OF CD95-Fc ISOFORMS
WO2014121764A3 (en) 2-substituted-6-biarylmethylamino-9-cyclopentyl-9h-purine derivatives, use thereof as medicaments, and pharmaceutical compositions
MX2016001422A (en) Pharmaceutical compositions of fingolimod.
WO2014121055A3 (en) Flap modulators
WO2014159061A3 (en) Benzo-fused heterocyclic derivatives useful as agonists of gpr120
WO2012155226A8 (en) Method for producing pyrostegia venusta derivatives, pyrostegia venusta derivatives, pharmaceutical compositions and uses thereof
WO2015052568A3 (en) Solid forms of curcumin and derivatives thereof
WO2014056851A3 (en) Flavor and fragrance formulation (i)
WO2014166836A8 (en) Growth hormone compound formulation
MX359955B (en) Flavor and fragrance formulation (iii).
WO2014033751A3 (en) Pharmaceutical composition of propofol

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2013833549

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13833549

Country of ref document: EP

Kind code of ref document: A2