WO2014028780A3 - Antifungal compounds and methods of use - Google Patents

Antifungal compounds and methods of use Download PDF

Info

Publication number
WO2014028780A3
WO2014028780A3 PCT/US2013/055211 US2013055211W WO2014028780A3 WO 2014028780 A3 WO2014028780 A3 WO 2014028780A3 US 2013055211 W US2013055211 W US 2013055211W WO 2014028780 A3 WO2014028780 A3 WO 2014028780A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
use
antifungal compounds
antifungal
compounds
Prior art date
Application number
PCT/US2013/055211
Other languages
French (fr)
Other versions
WO2014028780A2 (en
Inventor
Bassam Damaj
Richard Martin
Original Assignee
Nexmed Holdings, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201261683710P priority Critical
Priority to US61/683,710 priority
Application filed by Nexmed Holdings, Inc. filed Critical Nexmed Holdings, Inc.
Publication of WO2014028780A2 publication Critical patent/WO2014028780A2/en
Publication of WO2014028780A3 publication Critical patent/WO2014028780A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Abstract

Disclosed herein are compositions and methods for treating fungus infections of skin using tolnaftate and other antifungal agents.
PCT/US2013/055211 2012-08-15 2013-08-15 Antifungal compounds and methods of use WO2014028780A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201261683710P true 2012-08-15 2012-08-15
US61/683,710 2012-08-15

Publications (2)

Publication Number Publication Date
WO2014028780A2 WO2014028780A2 (en) 2014-02-20
WO2014028780A3 true WO2014028780A3 (en) 2014-05-01

Family

ID=50101613

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/055211 WO2014028780A2 (en) 2012-08-15 2013-08-15 Antifungal compounds and methods of use

Country Status (1)

Country Link
WO (1) WO2014028780A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090258098A1 (en) * 2008-04-15 2009-10-15 Lane Rolling Penetrating carrier, antifungal composition using the same and method for treatment of dermatophyte infections
WO2011075654A1 (en) * 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating inflammation of skin
US20110237558A1 (en) * 2008-10-03 2011-09-29 William Shifeng Stabilized composition for treating psoriasis
WO2012075107A2 (en) * 2010-12-02 2012-06-07 Nexmed Holdings, Inc. Active enantiomer of dodecyl 2-(n,n-dimethylamino)-propionate

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090258098A1 (en) * 2008-04-15 2009-10-15 Lane Rolling Penetrating carrier, antifungal composition using the same and method for treatment of dermatophyte infections
US20110237558A1 (en) * 2008-10-03 2011-09-29 William Shifeng Stabilized composition for treating psoriasis
WO2011075654A1 (en) * 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating inflammation of skin
WO2012075107A2 (en) * 2010-12-02 2012-06-07 Nexmed Holdings, Inc. Active enantiomer of dodecyl 2-(n,n-dimethylamino)-propionate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MEIER-DAVIS, SR ET AL.: 'Enhancing the Skin Flux of Tolnaftate Utilizing the Novel Excipient, Dodecyl-2-N,N-Dimethylaminopropionate (DDAIP).' JOURNAL OF PHARMACEUTICS & DRUG DELIVERY RESEARCH, [Online] vol. 1, no. 1, 13 August 2012, pages 1 - 3 Retrieved from the Internet: <URL:http://www.scitechnol.com/2325-960412325-9604-1-102.pdf> [retrieved on 2013-12-20] *

Also Published As

Publication number Publication date
WO2014028780A2 (en) 2014-02-20

Similar Documents

Publication Publication Date Title
IN2015DN01480A (en) Methods and compositions for treatment of a genetic condition
WO2011113606A8 (en) Anti-infective compounds
WO2014113089A3 (en) Signal-sensor polynucleotides for the alteration of cellular phenotypes
TW201704217A (en) Heterocyclic compounds and uses thereof
TWI581711B (en) Compositions for the protection of agrarian corps, the use thereof and method for controlling phytopathogenic fungi in agrarian crops
SG190230A1 (en) Spiro-oxindole mdm2 antagonists
EP2877159B8 (en) Efflux inhibitor compositions and methods of treatment using the same
WO2011060049A3 (en) Spiro-oxindole mdm2 antagonists
WO2012024620A3 (en) Autotaxin inhibitors and uses thereof
WO2012106735A3 (en) Plasma-assisted skin treatment
TW201300375A (en) Heterocyclic autotaxin inhibitors and uses thereof
MX2013015079A (en) Nitrogen containing compounds and their use.
WO2010090860A3 (en) Methods and compositions for treating bacterial infection
TW201728592A (en) IRAK inhibitors and uses thereof
WO2014062720A3 (en) Methods of treating cancer
SG183188A1 (en) Forms of rifaximin and uses thereof
WO2013122888A3 (en) Methods of treating bacterial infections
EP3054940A4 (en) Compositions and methods for treating non-alcoholic steatohepatitis
TWI548621B (en) Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith
TW201347675A (en) Use of pro-fungicides of UK-2A for control of soybean rust
CA2864120A1 (en) Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
EP2669289A4 (en) Phosphorus substituted group-containing quinoline-like compound, its preparation process, medical composition containing the compound and application
IN2014DN09346A (en) New diazaspirocycloalkane and azaspirocycloalkane
WO2013177062A3 (en) Methods for improving safety of blood-brain barrier transport
UA116981C2 (en) Compounds for treating spinal muscular atrophy

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13829185

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct app. not ent. europ. phase

Ref document number: 13829185

Country of ref document: EP

Kind code of ref document: A2