WO2014022867A8 - Cathéters à ballons multiples endovasculaires à diffuseur optique pour le traitement de sténoses vasculaires - Google Patents

Cathéters à ballons multiples endovasculaires à diffuseur optique pour le traitement de sténoses vasculaires Download PDF

Info

Publication number
WO2014022867A8
WO2014022867A8 PCT/US2013/053671 US2013053671W WO2014022867A8 WO 2014022867 A8 WO2014022867 A8 WO 2014022867A8 US 2013053671 W US2013053671 W US 2013053671W WO 2014022867 A8 WO2014022867 A8 WO 2014022867A8
Authority
WO
WIPO (PCT)
Prior art keywords
lumen
catheter shaft
occlusion balloons
treatment
balloon catheters
Prior art date
Application number
PCT/US2013/053671
Other languages
English (en)
Other versions
WO2014022867A1 (fr
Inventor
Richard Noddin
Christopher PIERSON
Ronald UTECHT
Original Assignee
Alumend, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alumend, Llc filed Critical Alumend, Llc
Publication of WO2014022867A1 publication Critical patent/WO2014022867A1/fr
Publication of WO2014022867A8 publication Critical patent/WO2014022867A8/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1011Multiple balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/1204Type of occlusion temporary occlusion
    • A61B17/12045Type of occlusion temporary occlusion double occlusion, e.g. during anastomosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/12195Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices comprising a curable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/94Stents retaining their form, i.e. not being deformable, after placement in the predetermined place
    • A61F2/945Stents retaining their form, i.e. not being deformable, after placement in the predetermined place hardenable, e.g. stents formed in situ
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B2018/1807Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using light other than laser radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/005Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0058Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1011Multiple balloon catheters
    • A61M2025/1013Multiple balloon catheters with concentrically mounted balloons, e.g. being independently inflatable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1052Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1079Balloon catheters with special features or adapted for special applications having radio-opaque markers in the region of the balloon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente invention concerne un dispositif thérapeutique vasculaire d'intervention (100) comprenant une tige de cathéter (110) comportant une paire de ballons d'occlusion (132, 134), un ballon de dilatation (136) disposé sur la tige de cathéter entre les ballons d'occlusion, une première lumière de gonflage (112) et une deuxième lumière de gonflage (113) conçues pour alimenter en fluide de gonflage un ballon disposé de manière proximale et un ballon distal parmi les ballons d'occlusion, une troisième lumière de gonflage (115) conçue pour alimenter en fluide de gonflage le ballon de dilatation, une lumière principale (111) s'étendant sur toute la longueur du cathéter et conçue pour recevoir de manière coulissante un fil de guidage, et une lumière de perfusion (114) s'étendant à partir d'une extrémité proximale de la tige de cathéter en direction de l'extrémité distale de la tige de cathéter et se terminant au niveau d'un orifice de sortie (140) de perfusion situé entre les ballons d'occlusion. Le dispositif selon l'invention comprend une fibre optique (480) conçue pour être insérée dans la lumière principale à la place du fil de guidage.
PCT/US2013/053671 2012-08-03 2013-08-05 Cathéters à ballons multiples endovasculaires à diffuseur optique pour le traitement de sténoses vasculaires WO2014022867A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261679591P 2012-08-03 2012-08-03
US61/679,591 2012-08-03
US201361794725P 2013-03-15 2013-03-15
US61/794,725 2013-03-15

Publications (2)

Publication Number Publication Date
WO2014022867A1 WO2014022867A1 (fr) 2014-02-06
WO2014022867A8 true WO2014022867A8 (fr) 2014-12-31

Family

ID=49029196

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/053671 WO2014022867A1 (fr) 2012-08-03 2013-08-05 Cathéters à ballons multiples endovasculaires à diffuseur optique pour le traitement de sténoses vasculaires

Country Status (1)

Country Link
WO (1) WO2014022867A1 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104434258A (zh) * 2014-11-28 2015-03-25 苏州亘科医疗科技有限公司 一种多功能球囊扩张导管
US20180056086A1 (en) * 2015-03-18 2018-03-01 Mor Research Applications Ltd. Percutaneous modification of vascular extracellular matrix to prevent and treat vascular restenosis
CN107343980A (zh) * 2016-04-21 2017-11-14 青岛智辰生物科技有限公司 一种多腔道球囊导管
TR201609694A2 (tr) * 2016-07-13 2017-01-23 Alper Erkin Vari̇s tedavi̇si̇nde kullanilacak yeni̇ bi̇r damar i̇çi̇ mekanoki̇myasal ablasyon si̇stemi̇
EP3668416A1 (fr) * 2017-08-17 2020-06-24 Koninklijke Philips N.V. Dispositifs d'occlusion temporaire à ballonnet, systèmes et procédés de prévention d'écoulement à travers une perforation vasculaire
US11819229B2 (en) 2019-06-19 2023-11-21 Boston Scientific Scimed, Inc. Balloon surface photoacoustic pressure wave generation to disrupt vascular lesions
CN109224264B (zh) * 2018-07-30 2020-12-08 郑州大学第一附属医院 用于心血管介入治疗的锥形扩张球囊
CN109700494A (zh) * 2018-08-03 2019-05-03 东莞天天向上医疗科技有限公司 一种多通道和多球囊的血管内快速止血球囊导管
US11541204B2 (en) * 2018-09-26 2023-01-03 W. L. Gore & Associates, Inc. Cyclic expansion tissue treatment programs and associated systems
US11090467B2 (en) 2018-10-02 2021-08-17 Alucent Biomedical, Inc. Apparatus and methods for scaffolding
US20200276038A1 (en) 2019-03-01 2020-09-03 Alucent Biomedical, Inc. Apparatus and methods for restoring tissue
US11717139B2 (en) 2019-06-19 2023-08-08 Bolt Medical, Inc. Plasma creation via nonaqueous optical breakdown of laser pulse energy for breakup of vascular calcium
US11660427B2 (en) 2019-06-24 2023-05-30 Boston Scientific Scimed, Inc. Superheating system for inertial impulse generation to disrupt vascular lesions
US20200406010A1 (en) 2019-06-26 2020-12-31 Boston Scientific Scimed, Inc. Side light direction plasma system to disrupt vascular lesions
US11426298B2 (en) * 2019-07-31 2022-08-30 Alucent Biomedical, Inc. Apparatus and methods for restoring tissue
US11583339B2 (en) 2019-10-31 2023-02-21 Bolt Medical, Inc. Asymmetrical balloon for intravascular lithotripsy device and method
US11529499B2 (en) * 2019-11-18 2022-12-20 Alucent Biomedical, Inc. Apparatus and methods for restoring tissue
CN111248964B (zh) * 2020-01-16 2020-11-13 张跃国 一种心血管内科介入装置
US11672599B2 (en) 2020-03-09 2023-06-13 Bolt Medical, Inc. Acoustic performance monitoring system and method within intravascular lithotripsy device
US20210290286A1 (en) 2020-03-18 2021-09-23 Bolt Medical, Inc. Optical analyzer assembly and method for intravascular lithotripsy device
US11707323B2 (en) 2020-04-03 2023-07-25 Bolt Medical, Inc. Electrical analyzer assembly for intravascular lithotripsy device
MX2023001718A (es) * 2020-08-13 2023-02-22 Cedars Sinai Medical Center Terapia ultravioleta interna.
US11672585B2 (en) 2021-01-12 2023-06-13 Bolt Medical, Inc. Balloon assembly for valvuloplasty catheter system
WO2022164879A1 (fr) * 2021-01-27 2022-08-04 Wake Forest University Health Sciences Cathéters à ballonnet à lumières multiples appropriés pour une cholangiographie d'occlusion par ballonnet et une dilatation de sphincter d'oddi et procédés d'utilisation associés
US20220273915A1 (en) * 2021-02-26 2022-09-01 Alucent Biomedical, Inc. Apparatus and methods for restoring tissue
US11648057B2 (en) 2021-05-10 2023-05-16 Bolt Medical, Inc. Optical analyzer assembly with safety shutdown system for intravascular lithotripsy device
CN215135662U (zh) * 2021-05-13 2021-12-14 王雅 球囊后方导管主体带有侧孔的球囊导管
US11806075B2 (en) 2021-06-07 2023-11-07 Bolt Medical, Inc. Active alignment system and method for laser optical coupling
EP4162967A1 (fr) * 2021-10-08 2023-04-12 WeMed Technologies GmbH Système de cathéter à ballonnet
US11839391B2 (en) 2021-12-14 2023-12-12 Bolt Medical, Inc. Optical emitter housing assembly for intravascular lithotripsy device
CN114082086B (zh) * 2021-12-23 2024-03-29 赛诺神畅医疗科技有限公司 一种球囊导引导管
CN114931695A (zh) * 2022-05-11 2022-08-23 上海玮沐医疗科技有限公司 一种带有光固化涂层的冲击波球囊导管装置
WO2024030552A1 (fr) * 2022-08-03 2024-02-08 Zeus Company Inc. Fibre optique polymère
WO2024049814A1 (fr) * 2022-08-31 2024-03-07 Medtronic, Inc. Cathéter à ballonnet multimodal comprenant un ballonnet pour lithotritie
WO2024045982A1 (fr) * 2022-09-02 2024-03-07 杭州矩正医疗科技有限公司 Cathéter à ballonnet de support de médicament et sa méthode de préparation, système de cathéter à ballonnet et méthode de génération de stent intravasculaire in situ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4191989A (en) * 1988-08-24 1990-03-23 Marvin J. Slepian Biodegradable polymeric endoluminal sealing
US5779673A (en) * 1995-06-26 1998-07-14 Focal, Inc. Devices and methods for application of intraluminal photopolymerized gels
US7060051B2 (en) * 2002-09-24 2006-06-13 Scimed Life Systems, Inc. Multi-balloon catheter with hydrogel coating
US7955365B2 (en) * 2006-04-07 2011-06-07 Medtronic Vascular, Inc. Closed loop catheter photopolymerization system and method of treating a vascular condition

Also Published As

Publication number Publication date
WO2014022867A1 (fr) 2014-02-06

Similar Documents

Publication Publication Date Title
WO2014022867A8 (fr) Cathéters à ballons multiples endovasculaires à diffuseur optique pour le traitement de sténoses vasculaires
ATE462467T1 (de) Intravaskulärer dilatationsinfusionskatheter
WO2007089570A3 (fr) Catheters de commande de deflexion, catheters d'appui et procedes d'utilisation
IN2012DE01084A (fr)
EP2572749A3 (fr) Cathéter de guidage à ballonnet d'accès distal
WO2009076215A3 (fr) Cathéter d'administration d'agent comportant un pont de gonflement entre deux ballonnets espacés l'un de l'autre sur l'axe
WO2013016056A3 (fr) Dispositifs et procédés de dilatation et d'irrigation transnasales des sinus
JP2013534845A5 (fr)
WO2007008784A3 (fr) Ballonnet de dispositif medical
EP1942976A4 (fr) Systeme de catheter a ballonnet servant a traiter les occlusions vasculaires
WO2005084130A3 (fr) Dispositifs d'acheminement d'extenseurs
WO2009105089A3 (fr) Système d'administration de stent entérique de type à échange rapide
WO2014113257A3 (fr) Cathéter de perfusion équipé d'un système de robinet pour fil-guide
WO2007039902A3 (fr) Dispositifs de traitement des vaisseaux
WO2007133959A3 (fr) Dispositif de traitement d'une occlusion chronique totale
WO2010062778A3 (fr) Cathéter de perfusion d'occlusion
WO2008028102A3 (fr) Système et procédé d'accès à une artère
WO2006113838A3 (fr) Catheters a ballonnet et procedes de fabrication
JP2006526464A5 (fr)
ATE251928T1 (de) Katheter zur medikamentenzuführung und dilatationskatheter mit medikamentenzuführung welche schnell ausgetaucht werden können
IN2014DN08042A (fr)
US20160114125A1 (en) Variable Stiffness Balloon Catheter and Related Systems and Methods
ATE329645T1 (de) Katheter zum verabreichen von strahlung
JP2016501655A (ja) 位置合わせを容易にするためのマーキングを有するカテーテル
WO2008060396A3 (fr) Méthode et appareil de traitement des thromboses des fistules artério-veineuses et des pontages d'abord en hémodialyse

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13752736

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct app. not ent. europ. phase

Ref document number: 13752736

Country of ref document: EP

Kind code of ref document: A1