WO2014018681A3 - Apparatus and methods for aliquotting frozen samples - Google Patents

Apparatus and methods for aliquotting frozen samples Download PDF

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Publication number
WO2014018681A3
WO2014018681A3 PCT/US2013/051902 US2013051902W WO2014018681A3 WO 2014018681 A3 WO2014018681 A3 WO 2014018681A3 US 2013051902 W US2013051902 W US 2013051902W WO 2014018681 A3 WO2014018681 A3 WO 2014018681A3
Authority
WO
WIPO (PCT)
Prior art keywords
frozen
sample
probe
ejector
coring
Prior art date
Application number
PCT/US2013/051902
Other languages
French (fr)
Other versions
WO2014018681A2 (en
Inventor
Larry CHIN
Todd BASQUE
III Albert J. BETTENCOURT
Original Assignee
Cryoxtract Instruments, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryoxtract Instruments, Llc filed Critical Cryoxtract Instruments, Llc
Priority to JP2015524429A priority Critical patent/JP2015527576A/en
Priority to BR112015001460A priority patent/BR112015001460A2/en
Priority to CN201380048181.9A priority patent/CN104641213A/en
Priority to AU2013295813A priority patent/AU2013295813A1/en
Priority to EP13747554.7A priority patent/EP2877827A2/en
Priority to CA2879171A priority patent/CA2879171A1/en
Publication of WO2014018681A2 publication Critical patent/WO2014018681A2/en
Publication of WO2014018681A3 publication Critical patent/WO2014018681A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A single-use coring probe for collecting a frozen aliquot from a frozen biological sample includes a hollow coring bit and an ejector adapted. The ejector is operable to eject a frozen sample core from the bit as it moves from a retracted position to an extended position. Use of the ejector converts the probe to a disabled configuration to discourage reuse of the coring probe to obtain another sample. The probe may include a locking mechanism adapted to prevent re-use of the single-use coring probe by locking the ejector in the extended position. A hand¬ held coring device can be used to take frozen sample cores from frozen samples. A tissue container is suitable for holding a frozen tissue sample in frozen storage and also for holding the sample while the sample is sectioned and/or a full-depth frozen sample core is extracted from the frozen tissue.
PCT/US2013/051902 2012-07-24 2013-07-24 Apparatus and methods for aliquotting frozen samples WO2014018681A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2015524429A JP2015527576A (en) 2012-07-24 2013-07-24 Apparatus and method for sorting frozen samples
BR112015001460A BR112015001460A2 (en) 2012-07-24 2013-07-24 digging probe, frozen sample core collection systems from a plurality of frozen samples, to collect frozen aliquots of frozen biological samples contained in sample containers, to store frozen tissue samples, methods of taking a frozen sample core from a sample frozen, to increase the likelihood that an operator will use only the digging probes, to prepare and sample a tissue sample in a tissue sample container, and to store a tissue sample, portable excavator, tray, tissue sample, u, aa preparation kit, tissue oyster, tissue transport to support the tissue sample, and combination of tissue transport and digging device.
CN201380048181.9A CN104641213A (en) 2012-07-24 2013-07-24 Apparatus and methods for aliquotting frozen samples
AU2013295813A AU2013295813A1 (en) 2012-07-24 2013-07-24 Apparatus and methods for aliquotting frozen samples
EP13747554.7A EP2877827A2 (en) 2012-07-24 2013-07-24 Apparatus and methods for aliquotting frozen samples
CA2879171A CA2879171A1 (en) 2012-07-24 2013-07-24 Apparatus and methods for aliquotting frozen samples

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261675016P 2012-07-24 2012-07-24
US61/675,016 2012-07-24
US201361784753P 2013-03-14 2013-03-14
US61/784,753 2013-03-14

Publications (2)

Publication Number Publication Date
WO2014018681A2 WO2014018681A2 (en) 2014-01-30
WO2014018681A3 true WO2014018681A3 (en) 2014-06-26

Family

ID=48949222

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/051902 WO2014018681A2 (en) 2012-07-24 2013-07-24 Apparatus and methods for aliquotting frozen samples

Country Status (8)

Country Link
US (1) US9689780B2 (en)
EP (1) EP2877827A2 (en)
JP (1) JP2015527576A (en)
CN (1) CN104641213A (en)
AU (1) AU2013295813A1 (en)
BR (1) BR112015001460A2 (en)
CA (1) CA2879171A1 (en)
WO (1) WO2014018681A2 (en)

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JP6801856B2 (en) * 2016-06-07 2020-12-16 国立大学法人大阪大学 Grip
CN106289860B (en) * 2016-08-31 2018-10-09 山东山大附属生殖医院有限公司 A kind of quick sampling device of biological sample
US9933459B1 (en) * 2016-11-11 2018-04-03 Fluke Corporation Magnetically coupled ground reference probe
WO2019108453A1 (en) * 2017-11-28 2019-06-06 Coopersurgical, Inc. Specimen containers and related methods
CN107843453B (en) * 2017-12-21 2024-01-23 上海泽泉科技股份有限公司 Speed-adjustable handheld low-temperature sample split charging instrument
CN112649224A (en) * 2020-12-17 2021-04-13 河南资环检测科技有限公司 Rock and ore sampling device
CN113607900B (en) * 2021-08-02 2024-02-20 山西麦畦食品有限公司 Food quality safety sampling device and sampling method thereof
CN115014835B (en) * 2022-06-10 2023-04-18 河北农业大学 Preparation method of Chinese cabbage stem tip frozen section
CN116399670B (en) * 2023-05-06 2024-04-09 精益和泰质量检测股份有限公司 High-speed tissue mashing and homogenizing machine for food detection

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Publication number Priority date Publication date Assignee Title
EP0999340A2 (en) * 1998-11-06 2000-05-10 SoilCore, Inc. Soil sampling device
DE20021405U1 (en) * 2000-12-18 2001-02-15 Clinico Verwaltungs Gmbh & Co Punching device for the single removal and transfer of tissue samples, in particular brain samples from cattle
US20050282246A1 (en) * 2004-06-18 2005-12-22 Covance, Inc. Frozen tissue microarray
WO2007084483A2 (en) * 2006-01-13 2007-07-26 President And Fellows Of Harvard College Systems, methods, and devices for frozen sample distribution
WO2007095366A2 (en) * 2006-02-13 2007-08-23 The Johns Hopkins University System and methods for sampling materials
US20080227662A1 (en) * 2006-09-08 2008-09-18 Jenrik Ag, Llc Livestock tissue identification system
EP2249140A1 (en) * 2009-05-07 2010-11-10 F. Hoffmann-La Roche AG Method for excising biological samples on a solid support

Also Published As

Publication number Publication date
WO2014018681A2 (en) 2014-01-30
US9689780B2 (en) 2017-06-27
CA2879171A1 (en) 2014-01-30
EP2877827A2 (en) 2015-06-03
CN104641213A (en) 2015-05-20
AU2013295813A1 (en) 2015-02-05
BR112015001460A2 (en) 2017-07-04
JP2015527576A (en) 2015-09-17
US20140053664A1 (en) 2014-02-27

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