WO2014016707A3 - Compositions comprising injectable biomaterial cement and radiopacity-improving agent - Google Patents

Compositions comprising injectable biomaterial cement and radiopacity-improving agent Download PDF

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Publication number
WO2014016707A3
WO2014016707A3 PCT/IB2013/002575 IB2013002575W WO2014016707A3 WO 2014016707 A3 WO2014016707 A3 WO 2014016707A3 IB 2013002575 W IB2013002575 W IB 2013002575W WO 2014016707 A3 WO2014016707 A3 WO 2014016707A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiopacity
cement
injectable biomaterial
improving agent
compositions
Prior art date
Application number
PCT/IB2013/002575
Other languages
French (fr)
Other versions
WO2014016707A2 (en
Inventor
Alejandro López
Hákan ENGQVIST
Original Assignee
Ossdsign Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ossdsign Ab filed Critical Ossdsign Ab
Priority to CN201380003872.7A priority Critical patent/CN103945875A/en
Publication of WO2014016707A2 publication Critical patent/WO2014016707A2/en
Publication of WO2014016707A3 publication Critical patent/WO2014016707A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Abstract

Compositions suitable for use as, for example, dental, craniofacial or long-bone fillers, percutaneous vertebroplasty agents and kyphoplasty agents, comprise an injectable biomaterial cement and a radiopacity-improving agent in an amount sufficient to improve the radiopacity of the injectable biomaterial in vivo. The radiopacity agent comprises strontium bromide (SrBr2) and/or strontium iodide (Srl2).
PCT/IB2013/002575 2012-05-09 2013-05-09 Compositions comprising injectable biomaterial cement and radiopacity-improving agent WO2014016707A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201380003872.7A CN103945875A (en) 2012-05-09 2013-05-09 Compositions comprising injectable biomaterial cement and radiopacity-improving agent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261644640P 2012-05-09 2012-05-09
US61/644,640 2012-05-09

Publications (2)

Publication Number Publication Date
WO2014016707A2 WO2014016707A2 (en) 2014-01-30
WO2014016707A3 true WO2014016707A3 (en) 2014-04-03

Family

ID=49725161

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/002575 WO2014016707A2 (en) 2012-05-09 2013-05-09 Compositions comprising injectable biomaterial cement and radiopacity-improving agent

Country Status (2)

Country Link
CN (1) CN103945875A (en)
WO (1) WO2014016707A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104368042A (en) * 2014-11-19 2015-02-25 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of brushite bone cement
CN104491924A (en) * 2015-01-05 2015-04-08 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of injectable medicine-carrying brushite bone cement
CN106031799A (en) * 2015-03-12 2016-10-19 中国科学院理化技术研究所 Calcium silicate/strontium salt bone cement and preparing method thereof
CN104826170B (en) * 2015-04-22 2017-12-22 山东明德生物医学工程有限公司 A kind of developability bone cement and preparation method and purposes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797431A (en) * 1986-04-08 1989-01-10 Dentsply Limited Glass/poly(carboxylic acid) cement compositions
US20100284919A1 (en) * 2007-10-12 2010-11-11 Kuros Biosurgery Ag Injectable Radio-Opaque Compositions for Tissue Augmentation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106301A (en) 1986-12-26 1992-04-21 G-C Dental Industrial Corp. Method for inspecting the root canal with a radiopaque impression material
US20030199605A1 (en) 2002-04-23 2003-10-23 Fischer Dan E. Hydrophilic endodontic sealing compositions and methods for using such compositions
FR2903684B1 (en) 2006-07-12 2008-10-17 Centre Nat Rech Scient NOVEL PHOSPHO-CALCO-STRONIC COMPOUND AND USES THEREOF IN ENDODONIC CEMENTS.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797431A (en) * 1986-04-08 1989-01-10 Dentsply Limited Glass/poly(carboxylic acid) cement compositions
US20100284919A1 (en) * 2007-10-12 2010-11-11 Kuros Biosurgery Ag Injectable Radio-Opaque Compositions for Tissue Augmentation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALEJANDRO LÓPEZ ET AL: "Calcium phosphate cements with strontium halides as radiopacifiers", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B: APPLIED BIOMATERIALS, vol. 102, no. 2, 1 February 2014 (2014-02-01), pages 250 - 259, XP055100218, ISSN: 1552-4973, DOI: 10.1002/jbm.b.33002 *
ALEJANDRO OTT CECILIA HÅKAN MARYAM LÓPEZ MARJAM PERSSON ENGQVIST MONTAZEROLGHAEM ET AL: "Strontium halides as degradable radiopacifiers", THE 22ND INTERDISCIPLINARY RESEARCH CONFERENCE ON INJECTABLE OSTEOARTICULAR BIOMATERIALS AND BONE, vol. 23, 10 May 2012 (2012-05-10) - 12 May 2012 (2012-05-12), pages 45, XP055100279 *

Also Published As

Publication number Publication date
CN103945875A (en) 2014-07-23
WO2014016707A2 (en) 2014-01-30

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