WO2014013081A3 - Method for the degradation of keratin and use of the keratin hydrolysate produced - Google Patents

Method for the degradation of keratin and use of the keratin hydrolysate produced Download PDF

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Publication number
WO2014013081A3
WO2014013081A3 PCT/EP2013/065363 EP2013065363W WO2014013081A3 WO 2014013081 A3 WO2014013081 A3 WO 2014013081A3 EP 2013065363 W EP2013065363 W EP 2013065363W WO 2014013081 A3 WO2014013081 A3 WO 2014013081A3
Authority
WO
WIPO (PCT)
Prior art keywords
keratin
degradation
hydrolysate produced
produced
conditions used
Prior art date
Application number
PCT/EP2013/065363
Other languages
French (fr)
Other versions
WO2014013081A2 (en
Inventor
Shukun Yu
Charlotte Horsmans Poulsen
Jon Gade HANSTED
Original Assignee
Dupont Nutrition Biosciences Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP13739700.6A priority Critical patent/EP2875144A2/en
Priority to CN201380038593.4A priority patent/CN104487588A/en
Priority to US14/415,564 priority patent/US20150152153A1/en
Priority to RU2015105827A priority patent/RU2015105827A/en
Priority to BR112015001226A priority patent/BR112015001226A2/en
Priority to IN10709DEN2014 priority patent/IN2014DN10709A/en
Application filed by Dupont Nutrition Biosciences Aps filed Critical Dupont Nutrition Biosciences Aps
Priority to MX2015000749A priority patent/MX2015000749A/en
Priority to AU2013291943A priority patent/AU2013291943B2/en
Publication of WO2014013081A2 publication Critical patent/WO2014013081A2/en
Publication of WO2014013081A3 publication Critical patent/WO2014013081A3/en
Priority to PH12014502764A priority patent/PH12014502764A1/en
Priority to AU2017206256A priority patent/AU2017206256A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4741—Keratin; Cytokeratin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/20—Animal feeding-stuffs from material of animal origin
    • A23K10/26—Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a method of producing keratin hydrolysate comprising the steps of: i) reacting keratin material with a protease; and ii) reacting keratin material with a chemical oxidant; wherein step ii occurs: a) after step i); b) during step i) when the selected protease hydrolyses under the pH conditions used for the chemical reaction and/or c) prior to step i) when the selected protease hydrolyses under the reaction conditions used for the chemical reaction; keratin hydrolysate so produced and uses thereof.
PCT/EP2013/065363 2012-07-20 2013-07-19 Method WO2014013081A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CN201380038593.4A CN104487588A (en) 2012-07-20 2013-07-19 Method for the degradation of keratin and use of the keratin hydrolysate produced
US14/415,564 US20150152153A1 (en) 2012-07-20 2013-07-19 Method
RU2015105827A RU2015105827A (en) 2012-07-20 2013-07-19 METHOD
BR112015001226A BR112015001226A2 (en) 2012-07-20 2013-07-19 keratin hydrolyzate production and commercial keratin degradation methods, use of a combination of hydrolysis and keratin hydrolyzate, keratin hydrolyzate, food additive composition, food and product.
IN10709DEN2014 IN2014DN10709A (en) 2012-07-20 2013-07-19
EP13739700.6A EP2875144A2 (en) 2012-07-20 2013-07-19 Method for the degradation of keratin and use of the keratin hydrolysate produced
MX2015000749A MX2015000749A (en) 2012-07-20 2013-07-19 Method for the degradation of keratin and use of the keratin hydrolysate produced.
AU2013291943A AU2013291943B2 (en) 2012-07-20 2013-07-19 Method for the degradation of keratin and use of the keratin hydrolysate produced
PH12014502764A PH12014502764A1 (en) 2012-07-20 2014-12-10 Method
AU2017206256A AU2017206256A1 (en) 2012-07-20 2017-07-20 Method for the degradation of keratin and use of the keratin hydrolysate produced

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1212937.5 2012-07-20
GBGB1212937.5A GB201212937D0 (en) 2012-07-20 2012-07-20 Method

Publications (2)

Publication Number Publication Date
WO2014013081A2 WO2014013081A2 (en) 2014-01-23
WO2014013081A3 true WO2014013081A3 (en) 2014-04-10

Family

ID=46881718

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2013/065363 WO2014013081A2 (en) 2012-07-20 2013-07-19 Method

Country Status (11)

Country Link
US (1) US20150152153A1 (en)
EP (1) EP2875144A2 (en)
CN (1) CN104487588A (en)
AU (2) AU2013291943B2 (en)
BR (1) BR112015001226A2 (en)
GB (1) GB201212937D0 (en)
IN (1) IN2014DN10709A (en)
MX (1) MX2015000749A (en)
PH (1) PH12014502764A1 (en)
RU (1) RU2015105827A (en)
WO (1) WO2014013081A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3328875A1 (en) 2015-07-28 2018-06-06 Glaxosmithkline Intellectual Property (No. 2) Limited Betuin derivatives for preventing or treating hiv infections
JP2018521093A (en) 2015-07-28 2018-08-02 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ Vetine derivatives for preventing or treating HIV infection
KR20180054826A (en) 2015-09-24 2018-05-24 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 Compounds having HIV maturation inhibitory activity
CN105293599B (en) * 2015-10-10 2017-11-21 北海富安源生物科技有限公司 One kind improves hair-hydrolyzation synthetic ratio and prepares the protectant method of Ecology
US20190023733A1 (en) 2016-01-20 2019-01-24 Glaxosmithkline Intellectual Property (No.2) Limited Amine derivatives of lupanes with hiv maturation inhibitory activity
KR101859421B1 (en) * 2017-01-31 2018-05-21 주식회사 케라메딕스 Injectable composition for prevention of depilation or improvement of hair growth
CN106867000A (en) * 2017-03-16 2017-06-20 苏州佰锐生物科技有限公司 A kind of method for promoting keratolysis and enhancing keratin material intensity
CA3059963C (en) * 2017-05-30 2024-04-02 Mars, Incorporated Methods for producing feather-based food products
FI127941B (en) 2017-10-02 2019-05-31 Hkscan Oyj Method of modifying feather raw material
PT3784349T (en) 2018-04-24 2024-01-22 Viiv Healthcare Uk No 5 Ltd Compounds with hiv maturation inhibitory activity
US20210346283A1 (en) * 2019-07-29 2021-11-11 Keramedix Inc. Injectable composition for preventing hair loss or stimulating hair growth
CN113307860A (en) * 2021-06-11 2021-08-27 四川大学 Method for extracting keratin from cow hair recovered from tanning based on biological enzymolysis
CN113980943A (en) * 2021-12-18 2022-01-28 河北省微生物研究所有限公司 Complex enzyme preparation containing collagenase and application thereof in treating leather leftovers

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD244760A1 (en) * 1985-12-23 1987-04-15 Dessau Tornau Impfstoffwerk METHOD FOR PRODUCING AN EGRICE HYDROLYZATE
WO1990001023A1 (en) * 1988-07-19 1990-02-08 American Biogenetics Corporation Method for solubilizing keratinaceous materials using alkaline hydrogen peroxide solution
WO2002036801A2 (en) * 2000-11-03 2002-05-10 Henkel Kommanditgesellschaft Auf Aktien Extruded protein hydrolysate, method for production and use thereof
JP2005120286A (en) * 2003-10-17 2005-05-12 Little Scientist:Kk Hydrolyzate of feather keratin or its salt and cosmetic composition containing those and method for producing hydrolyzate of feather keratin or its salt
WO2013070798A2 (en) * 2011-11-07 2013-05-16 Mars, Incorporated Food protein ingredient and methods for producing

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006046878A1 (en) * 2004-10-28 2006-05-04 Canesis Network Limited Production of fine particulates from keratin fibres

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD244760A1 (en) * 1985-12-23 1987-04-15 Dessau Tornau Impfstoffwerk METHOD FOR PRODUCING AN EGRICE HYDROLYZATE
WO1990001023A1 (en) * 1988-07-19 1990-02-08 American Biogenetics Corporation Method for solubilizing keratinaceous materials using alkaline hydrogen peroxide solution
WO2002036801A2 (en) * 2000-11-03 2002-05-10 Henkel Kommanditgesellschaft Auf Aktien Extruded protein hydrolysate, method for production and use thereof
JP2005120286A (en) * 2003-10-17 2005-05-12 Little Scientist:Kk Hydrolyzate of feather keratin or its salt and cosmetic composition containing those and method for producing hydrolyzate of feather keratin or its salt
WO2013070798A2 (en) * 2011-11-07 2013-05-16 Mars, Incorporated Food protein ingredient and methods for producing

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ADRIANO BRANDELLI ET AL: "Biochemical features of microbial keratinases and their production and applications", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 85, no. 6, 29 December 2009 (2009-12-29), pages 1735 - 1750, XP019778631, ISSN: 1432-0614 *
DATABASE WPI Week 200537, Derwent World Patents Index; AN 2005-359273, XP002716407 *
RINKY RAJPUT ET AL: "Cloning and characterization of a thermostable detergent-compatible recombinant keratinase from Bacillus pumilus KS12", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, vol. 58, no. 2, 19 April 2011 (2011-04-19), pages 109 - 118, XP055087922, DOI: 10.1002/bab.16 *

Also Published As

Publication number Publication date
AU2013291943A1 (en) 2015-01-22
GB201212937D0 (en) 2012-09-05
RU2015105827A (en) 2016-09-10
EP2875144A2 (en) 2015-05-27
CN104487588A (en) 2015-04-01
US20150152153A1 (en) 2015-06-04
AU2017206256A1 (en) 2017-08-10
BR112015001226A2 (en) 2018-08-28
IN2014DN10709A (en) 2015-09-04
PH12014502764A1 (en) 2015-02-09
WO2014013081A2 (en) 2014-01-23
MX2015000749A (en) 2015-04-14
AU2013291943B2 (en) 2017-05-11

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