WO2014009823A1 - Flow system for medical lines - Google Patents

Flow system for medical lines Download PDF

Info

Publication number
WO2014009823A1
WO2014009823A1 PCT/IB2013/054768 IB2013054768W WO2014009823A1 WO 2014009823 A1 WO2014009823 A1 WO 2014009823A1 IB 2013054768 W IB2013054768 W IB 2013054768W WO 2014009823 A1 WO2014009823 A1 WO 2014009823A1
Authority
WO
WIPO (PCT)
Prior art keywords
diaphragm
fluid
tubular fitting
introducer
lateral tubular
Prior art date
Application number
PCT/IB2013/054768
Other languages
French (fr)
Inventor
Gianni Guala
Original Assignee
Industrie Borla S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP13744817.1A priority Critical patent/EP2869889B1/en
Priority to CN201380036989.5A priority patent/CN104602753B/en
Application filed by Industrie Borla S.P.A. filed Critical Industrie Borla S.P.A.
Priority to JP2015521088A priority patent/JP6470686B2/en
Priority to SG11201500078UA priority patent/SG11201500078UA/en
Priority to MX2015000111A priority patent/MX355592B/en
Priority to US14/413,938 priority patent/US9585999B2/en
Priority to ES13744817T priority patent/ES2907458T3/en
Priority to PL13744817T priority patent/PL2869889T3/en
Priority to NZ703613A priority patent/NZ703613A/en
Priority to AU2013288398A priority patent/AU2013288398B2/en
Priority to RS20220228A priority patent/RS63022B1/en
Priority to BR112015000200-5A priority patent/BR112015000200B1/en
Priority to HRP20220292TT priority patent/HRP20220292T1/en
Priority to DK13744817.1T priority patent/DK2869889T3/en
Publication of WO2014009823A1 publication Critical patent/WO2014009823A1/en
Priority to ZA2015/00235A priority patent/ZA201500235B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/367—Circuit parts not covered by the preceding subgroups of group A61M1/3621
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1083—Tube connectors; Tube couplings having a plurality of female connectors, e.g. Luer connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/24—Check- or non-return valves
    • A61M2039/2433—Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/24—Check- or non-return valves
    • A61M2039/2433—Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
    • A61M2039/2446—Flexible disc
    • A61M2039/246—Flexible disc being fixed along all or a part of its periphery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • A61M2039/261—Valves closing automatically on disconnecting the line and opening on reconnection thereof where the fluid space within the valve is increasing upon disconnection

Definitions

  • the subject of the present invention is a flow system for medical lines, in particular for haemodialysis , of the type comprising a flow component having a main duct for a primary fluid and at least one lateral tubular fitting with female luer cone communicating with the main duct through a valve.
  • a flow component of the type defined above is known from the European patent No. EP-B-1661599 filed in the name of the present applicant, in which the valve is a so-called anti-siphon valve, including a diaphragm constituted by the bottom wall of a cup- shaped element made of elastically deformable material, the outer peripheral edge of which is normally kept in fluid-tight contact against an annular valve seat of the lateral tubular fitting.
  • the valve is a so-called anti-siphon valve, including a diaphragm constituted by the bottom wall of a cup- shaped element made of elastically deformable material, the outer peripheral edge of which is normally kept in fluid-tight contact against an annular valve seat of the lateral tubular fitting.
  • This arrangement in addition to being relatively complicated, may entail the risk of the valve being opened by the auxiliary slider before the male luer- cone introducer provides the hermetic seal with the female luer cone of the tubular fitting, with consequent problems of contamination and leakage of fluid .
  • the object of the present invention is to overcome the above drawback and to provide a flow system for medical lines of the type defined in the pre-characterizing part of Claim 1 (and generally corresponding to what is described and illustrated in the already cited European patent No. EP-B-1661599) , in which opening of the valve upon insertion of the introducer of fluid takes place in a precise and reliable way and without any risk of contamination.
  • this object is achieved thanks to the fact that the diaphragm of the valve is prearranged for being pushed towards the aforesaid opening position as a result of the direct contact of thrust by the male luer-cone introducer of fluid and to the fact that the lateral tubular fitting is configured in such a way as to couple in a fluid- tight way with the aforesaid introducer before the latter comes into contact of thrust with the aforesaid diaphragm.
  • the lateral tubular fitting is made of a relatively yelding elastic material and is conveniently elastically expandable in a radial direction following upon fluid-tight coupling of the aforesaid introducer of fluid to the female luer cone of the lateral tubular fitting .
  • the radial expansion of the lateral tubular fitting may be conveniently obtained envisaging that its side wall is locally thinned axially.
  • FIG. 1 is a schematic perspective view of a flow system for medical lines according to the invention ;
  • FIG. 1 is a top plan view at a larger scale of the system of Figure 1 ;
  • Figure 3 is a longitudinal sectional view according to the line III-III of Figure 2 ;
  • FIG. 4 is a sectional view according to the line IV-IV of Figure 3;
  • Figure 5 is a perspective view of the open/close element of the anti-siphon valve of the flow component ;
  • FIG. 6 is a view in elevation of the lateral tubular fitting of the flow component.
  • FIG. 7 is a view in axial section according to the line VII-VII of Figure 6.
  • the flow system according to the invention represented in the drawings may be applied in particular to a medical haemodialysis line.
  • the flow system basically comprises a flow component 1 having a main duct 2 designed in use to be traversed by the flow of a primary fluid in the direction indicated by the arrow A, and a lateral tubular fitting 3 extending in a direction perpendicular to the duct 2 for introduction of a secondary fluid into the latter.
  • the lateral tubular fitting 3 is shaped like a female luer-lock connector, the luer-cone internal surface of which is designated by 4, and the internal end of which has an annular flange 5 fixed in a fluid- tight way at an annular collar 6 projecting laterally from the main duct 2.
  • the valve comprises an element 8 shaped like a cup turned upside down made of elastic material, for example, silicone, the side wall 9 of which rests on the bottom of the chamber 7 and the bottom wall of which, designated by 10, defines an elastically deformable transverse diaphragm, the perimetral edge 11 of which is normally set in hermetic contact against an annular valve seat 12 with conical surface formed inside the annular flange 5 of the lateral tubular fitting 3.
  • the hermetic contact is obtained thanks to the axial thrust applied by the side wall 9 of the cup-shaped element 8 on the diaphragm 10.
  • the diaphragm 10 is formed with a ring of axial projections 13 (in the example illustrated, four in number) , which radially face the base of the female luer cone 4 of the lateral tubular fitting 3 and the function of which will be clarified in what follows.
  • the lateral tubular fitting 3 advantageously has two peculiar characteristics: in the first place, it is made of a relatively yelding i.e. compliant elastic material (for example, polybutylene-terephthalate and analogues) , and preferably its side wall is locally thinned axially, for example, in the way represented in Figure 7, with two diametrally opposite portions 14 thinner than the remaining portions 15, which are thicker.
  • a relatively yelding i.e. compliant elastic material for example, polybutylene-terephthalate and analogues
  • the female luer-cone internal surface 4 is obtained with the minimum tolerance possible in proportion to the size of a normal male luer-cone introducer of fluid, partially represented schematically with a dashed line and designated by H in Figures 3 and 4.
  • the main duct 2 has, in a region axially corresponding to the chamber 8, a portion 16 with an internal wall having a convergent-divergent profile.
  • This profile is defined by a localized narrowing of rounded shape 17 of the internal wall of the portion 16, upstream of which (with respect to the direction of flow A of the primary fluid) the convergent part is defined, in communication with the chamber 7 through a first radial passage 18, and downstream of which the divergent part is defined, in turn in communication with the chamber 7 through a second radial passage 19.
  • This conformation which however is not strictly necessary in relation to operation of the valve, corresponds to the one described and illustrated in the already cited patent No. EP-B-1661599, with the functional effect that will also be described in what follows.
  • valve defined by the cup-shaped element 8 is normally set in the closing position, with the peripheral edge 11 of the diaphragm 10 kept in fluid-tight contact against the annular valve seat 12 as a result of the axial thrust exerted by the side wall 9.
  • the male luer-cone introducer H For introduction of a secondary fluid within the main duct 2 (or else for extraction of fluid from the main duct 2), the male luer-cone introducer H is introduced axially into the lateral tubular fitting 4 and pushed therein. Considering the minimal tolerance referred to above, the hermetic seal between the male luer cone of the introducer H and the female luer cone 4 of the lateral tubular fitting 3 is obtained already at a certain distance from the axial projections 13 of the diaphragm 10, i.e., approximately in the area represented in Figures 3 and 4.
  • the further axial advance of the introducer H made possible by the radially yelding and possibly locally thinned conformation of the lateral tubular fitting 3 referred to above, produces interaction thereof with the axial projections 13 of the diaphragm 10 and separation of the perimetral edge 11 of the latter from the valve seat 12, against the action of thrust applied by the side wall 9.
  • the cross section with a convergent-divergent profile 16 defines a Venturi tube designed to prevent the stagnation of the secondary fluid within the chamber 7.
  • the primary fluid in the main duct 2 achieves not only an effect of emptying of the chamber 7, but also an effective action of continuous flushing thereof.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)

Abstract

A flow system for medical lines comprising a flow component (1) having a main duct (2) and at least one lateral tubular fitting (3) with female luer cone (4) communicating with the main duct (2) through a valve (8), which includes a transverse diaphragm (10) normally kept in fluid-tight contact against an annular valve seat (12) of the lateral tubular fitting (3), which can be moved away from this into an opening position following upon insertion of a male luer-cone introducer of fluid (H) into the lateral tubular fitting (3). The diaphragm (10) is prearranged for being pushed into the opening position directly by the introducer (H), and the lateral tubular fitting (3) is configured in such a way as to couple in a fluid-tight way with the introducer (H) before the latter comes into contact of thrust with the diaphragm (10).

Description

"Flow system for medical lines"
-k -k -k -k
Field of the invention
The subject of the present invention is a flow system for medical lines, in particular for haemodialysis , of the type comprising a flow component having a main duct for a primary fluid and at least one lateral tubular fitting with female luer cone communicating with the main duct through a valve.
Prior art
A flow component of the type defined above is known from the European patent No. EP-B-1661599 filed in the name of the present applicant, in which the valve is a so-called anti-siphon valve, including a diaphragm constituted by the bottom wall of a cup- shaped element made of elastically deformable material, the outer peripheral edge of which is normally kept in fluid-tight contact against an annular valve seat of the lateral tubular fitting. As is also described in the patent No. EP-B-1093828, which is also filed in the name of the present applicant, the sealing edge of this valve can be moved away from the corresponding annular valve seat, to an opening position, following upon insertion of a male luer-cone introducer of fluid within the female luer cone of the lateral tubular fitting. It is hence a two-way valve of the so-called "luer activated" type, opening of which is controlled mechanically, rather than simply by the pressure of the fluid introduced into the lateral tubular fitting.
Mechanical activation is normally obtained in the case of valves of this sort, with the aid of additional components. For example, from the Italian patent No. IT-B-1291508, which is also filed in the name of the present applicant, opening of a diaphragm valve obtained as a result of insertion of the male luer-cone introducer of fluid within a female luer-cone fitting is obtained with the aid of an auxiliary tubular slider that is axially mobile within the fitting and rests against the diaphragm of the valve. Opening of the valve is thus obtained as a result of the axial thrust applied on the diaphragm by the auxiliary slider, which is in turn moved by the male luer-cone introducer.
A similar solution is described in the document No. US-5, 565, 938A.
This arrangement, in addition to being relatively complicated, may entail the risk of the valve being opened by the auxiliary slider before the male luer- cone introducer provides the hermetic seal with the female luer cone of the tubular fitting, with consequent problems of contamination and leakage of fluid .
Summary of the invention
The object of the present invention is to overcome the above drawback and to provide a flow system for medical lines of the type defined in the pre-characterizing part of Claim 1 (and generally corresponding to what is described and illustrated in the already cited European patent No. EP-B-1661599) , in which opening of the valve upon insertion of the introducer of fluid takes place in a precise and reliable way and without any risk of contamination.
According to the invention, this object is achieved thanks to the fact that the diaphragm of the valve is prearranged for being pushed towards the aforesaid opening position as a result of the direct contact of thrust by the male luer-cone introducer of fluid and to the fact that the lateral tubular fitting is configured in such a way as to couple in a fluid- tight way with the aforesaid introducer before the latter comes into contact of thrust with the aforesaid diaphragm.
According to a preferred embodiment of the invention, the lateral tubular fitting is made of a relatively yelding elastic material and is conveniently elastically expandable in a radial direction following upon fluid-tight coupling of the aforesaid introducer of fluid to the female luer cone of the lateral tubular fitting .
The radial expansion of the lateral tubular fitting may be conveniently obtained envisaging that its side wall is locally thinned axially.
Brief description of the drawings
The invention will now be described in detail with reference to the annexed drawings, which are provided purely by way of non-limiting example and in which :
- Figure 1 is a schematic perspective view of a flow system for medical lines according to the invention ;
- Figure 2 is a top plan view at a larger scale of the system of Figure 1 ;
Figure 3 is a longitudinal sectional view according to the line III-III of Figure 2 ;
- Figure 4 is a sectional view according to the line IV-IV of Figure 3;
Figure 5 is a perspective view of the open/close element of the anti-siphon valve of the flow component ;
- Figure 6 is a view in elevation of the lateral tubular fitting of the flow component; and
- Figure 7 is a view in axial section according to the line VII-VII of Figure 6.
Detailed description of the invention
The flow system according to the invention represented in the drawings may be applied in particular to a medical haemodialysis line.
The flow system basically comprises a flow component 1 having a main duct 2 designed in use to be traversed by the flow of a primary fluid in the direction indicated by the arrow A, and a lateral tubular fitting 3 extending in a direction perpendicular to the duct 2 for introduction of a secondary fluid into the latter.
The lateral tubular fitting 3 is shaped like a female luer-lock connector, the luer-cone internal surface of which is designated by 4, and the internal end of which has an annular flange 5 fixed in a fluid- tight way at an annular collar 6 projecting laterally from the main duct 2.
Defined between the annular flange 5 and the annular collar 6 is a chamber 7 for a two-way valve, the general conformation of which is known from the already cited European patents Nos . EP-B-1093828 and EP-B-1661599. In detail, and as is more clearly visible also in Figure 5, the valve comprises an element 8 shaped like a cup turned upside down made of elastic material, for example, silicone, the side wall 9 of which rests on the bottom of the chamber 7 and the bottom wall of which, designated by 10, defines an elastically deformable transverse diaphragm, the perimetral edge 11 of which is normally set in hermetic contact against an annular valve seat 12 with conical surface formed inside the annular flange 5 of the lateral tubular fitting 3. The hermetic contact is obtained thanks to the axial thrust applied by the side wall 9 of the cup-shaped element 8 on the diaphragm 10.
The diaphragm 10 is formed with a ring of axial projections 13 (in the example illustrated, four in number) , which radially face the base of the female luer cone 4 of the lateral tubular fitting 3 and the function of which will be clarified in what follows.
The lateral tubular fitting 3 advantageously has two peculiar characteristics: in the first place, it is made of a relatively yelding i.e. compliant elastic material (for example, polybutylene-terephthalate and analogues) , and preferably its side wall is locally thinned axially, for example, in the way represented in Figure 7, with two diametrally opposite portions 14 thinner than the remaining portions 15, which are thicker.
In the second place, the female luer-cone internal surface 4 is obtained with the minimum tolerance possible in proportion to the size of a normal male luer-cone introducer of fluid, partially represented schematically with a dashed line and designated by H in Figures 3 and 4.
These characteristics contribute to achieving the functional effect that will be discussed in what follows .
In the case of the example illustrated, the main duct 2 has, in a region axially corresponding to the chamber 8, a portion 16 with an internal wall having a convergent-divergent profile. This profile is defined by a localized narrowing of rounded shape 17 of the internal wall of the portion 16, upstream of which (with respect to the direction of flow A of the primary fluid) the convergent part is defined, in communication with the chamber 7 through a first radial passage 18, and downstream of which the divergent part is defined, in turn in communication with the chamber 7 through a second radial passage 19. This conformation, which however is not strictly necessary in relation to operation of the valve, corresponds to the one described and illustrated in the already cited patent No. EP-B-1661599, with the functional effect that will also be described in what follows.
In operation, as explained previously, the valve defined by the cup-shaped element 8 is normally set in the closing position, with the peripheral edge 11 of the diaphragm 10 kept in fluid-tight contact against the annular valve seat 12 as a result of the axial thrust exerted by the side wall 9.
For introduction of a secondary fluid within the main duct 2 (or else for extraction of fluid from the main duct 2), the male luer-cone introducer H is introduced axially into the lateral tubular fitting 4 and pushed therein. Considering the minimal tolerance referred to above, the hermetic seal between the male luer cone of the introducer H and the female luer cone 4 of the lateral tubular fitting 3 is obtained already at a certain distance from the axial projections 13 of the diaphragm 10, i.e., approximately in the area represented in Figures 3 and 4. The further axial advance of the introducer H, made possible by the radially yelding and possibly locally thinned conformation of the lateral tubular fitting 3 referred to above, produces interaction thereof with the axial projections 13 of the diaphragm 10 and separation of the perimetral edge 11 of the latter from the valve seat 12, against the action of thrust applied by the side wall 9. In this way, there is allowed flow of the secondary fluid from the introducer H to the chamber 7 and thus into the main duct 2, or vice versa. In this step, the cross section with a convergent-divergent profile 16 defines a Venturi tube designed to prevent the stagnation of the secondary fluid within the chamber 7. Part of the flow of the primary liquid penetrates into the chamber 7 through the first passage 18 and comes out of this through the second passage 19, entrained thanks to the ejecting effect obtained by the aforesaid flow of the primary fluid in the area of the divergent profile. In this way, the primary fluid in the main duct 2 achieves not only an effect of emptying of the chamber 7, but also an effective action of continuous flushing thereof.
When the introducer H is taken out of the lateral tubular fitting 3, the latter is brought back again into its undeformed condition, and the side wall 9 of the cup-shaped element 8 brings the diaphragm 10 back into the closing position, pushing the perimetral edge 11 again into fluid-tight contact with the annular valve seat 12.
Of course, the details of construction and the embodiments may vary widely with respect to what has been described and illustrated herein, without thereby departing from the scope of the present invention as defined in the ensuing claims.

Claims

1. A flow system for medical lines comprising a flow component (1) having a main duct (2) for a primary fluid and at least one lateral tubular fitting (3) with female luer cone (4) communicating with the main duct (2) through a valve (8) including a transverse diaphragm (10) constituted by the bottom wall of a cup- shaped element (8) made of elastically deformable material, the outer peripheral edge (11) of which is normally kept in fluid-tight contact against an annular valve seat (12) of said lateral tubular fitting (3), and a male luer-cone introducer of secondary fluid (H) , which can be inserted into said lateral tubular fitting (3) with female luer cone (4) to displace said transverse diaphragm (10) into an opening position, said flow system being characterized in that said diaphragm (10) is prearranged for being pushed into said opening position as a result of the direct contact of thrust by said introducer (H) , and in that said lateral tubular fitting (3) is configured in such a way as to couple in a fluid-tight way with said introducer (H) before the latter comes into contact of thrust with said diaphragm (10).
2. The flow system according to Claim 1, characterized in that said lateral tubular fitting (3) is made of a relatively yelding elastic material and can expand elastically in a radial direction following upon fluid-tight coupling with said introducer (H) .
3. The flow system according to Claim 2, characterized in that said lateral tubular fitting (3) has a wall locally thinned axially (15) .
4. The flow system according to one or more of the preceding claims, characterized in that said diaphragm (10) has a ring of axial projections (13) radially facing said female luer cone (4) .
5. The flow system according to Claim 4, characterized in that the outer peripheral edge (11) of said diaphragm (10) is normally kept in fluid-tight contact against said annular valve seat (12) under the action of an axial thrust applied by the side wall (9) of said cup-shaped element (8); the deflection of said diaphragm (10) produced in use following upon the interaction between said introducer (H) and said axial projections (13) bringing about radial contraction of said peripheral edge (11) and its consequent separation from said annular valve seat (12) .
6. The flow system according to one or more of the preceding claims, characterized in that said main duct (2) has, in a position corresponding to said anti- siphon valve (8), an axial section (16, 17) with a convergent-divergent profile.
PCT/IB2013/054768 2012-07-09 2013-06-11 Flow system for medical lines WO2014009823A1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
NZ703613A NZ703613A (en) 2012-07-09 2013-06-11 Flow system for medical lines
PL13744817T PL2869889T3 (en) 2012-07-09 2013-06-11 Flow system for medical lines
JP2015521088A JP6470686B2 (en) 2012-07-09 2013-06-11 Medical line flow system
CN201380036989.5A CN104602753B (en) 2012-07-09 2013-06-11 Running system for medical circuit
MX2015000111A MX355592B (en) 2012-07-09 2013-06-11 Flow system for medical lines.
US14/413,938 US9585999B2 (en) 2012-07-09 2013-06-11 Flow system for medical lines
AU2013288398A AU2013288398B2 (en) 2012-07-09 2013-06-11 Flow system for medical lines
EP13744817.1A EP2869889B1 (en) 2012-07-09 2013-06-11 Flow system for medical lines
SG11201500078UA SG11201500078UA (en) 2012-07-09 2013-06-11 Flow system for medical lines
ES13744817T ES2907458T3 (en) 2012-07-09 2013-06-11 Flow system for medical lines
RS20220228A RS63022B1 (en) 2012-07-09 2013-06-11 Flow system for medical lines
BR112015000200-5A BR112015000200B1 (en) 2012-07-09 2013-06-11 flow system for medical lines
HRP20220292TT HRP20220292T1 (en) 2012-07-09 2013-06-11 Flow system for medical lines
DK13744817.1T DK2869889T3 (en) 2012-07-09 2013-06-11 Flow system for medical wires
ZA2015/00235A ZA201500235B (en) 2012-07-09 2015-01-13 Flow system for medical lines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITTO2012A000601 2012-07-09
IT000601A ITTO20120601A1 (en) 2012-07-09 2012-07-09 FLOW COMPONENT FOR MEDICAL LINES

Publications (1)

Publication Number Publication Date
WO2014009823A1 true WO2014009823A1 (en) 2014-01-16

Family

ID=46939858

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/054768 WO2014009823A1 (en) 2012-07-09 2013-06-11 Flow system for medical lines

Country Status (18)

Country Link
US (1) US9585999B2 (en)
EP (1) EP2869889B1 (en)
JP (1) JP6470686B2 (en)
CN (1) CN104602753B (en)
AU (1) AU2013288398B2 (en)
BR (1) BR112015000200B1 (en)
DK (1) DK2869889T3 (en)
ES (1) ES2907458T3 (en)
HR (1) HRP20220292T1 (en)
IT (1) ITTO20120601A1 (en)
MX (1) MX355592B (en)
NZ (1) NZ703613A (en)
PL (1) PL2869889T3 (en)
PT (1) PT2869889T (en)
RS (1) RS63022B1 (en)
SG (1) SG11201500078UA (en)
WO (1) WO2014009823A1 (en)
ZA (1) ZA201500235B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2015146142A1 (en) * 2014-03-26 2017-04-13 テルモ株式会社 Connector and infusion set
WO2017074693A1 (en) * 2015-10-28 2017-05-04 Carefusion 303, Inc. Closed iv access device with y-port needle-free connector
ITUB20155501A1 (en) * 2015-11-12 2017-05-12 Neovasc S R L CONNECTION DEVICE

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
WO2010022095A1 (en) 2008-08-20 2010-02-25 Icu Medical, Inc. Anti-reflux vial adaptors
US8323249B2 (en) 2009-08-14 2012-12-04 The Regents Of The University Of Michigan Integrated vascular delivery system
WO2011146769A2 (en) 2010-05-19 2011-11-24 Tangent Medical Technologies Llc Integrated vascular delivery system
US8814833B2 (en) 2010-05-19 2014-08-26 Tangent Medical Technologies Llc Safety needle system operable with a medical device
EP4119121A1 (en) 2011-08-18 2023-01-18 ICU Medical, Inc. Pressure-regulating vial adaptors
WO2013106757A1 (en) 2012-01-13 2013-07-18 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
WO2013142618A1 (en) 2012-03-22 2013-09-26 Icu Medical, Inc. Pressure-regulating vial adaptors
JP6382210B2 (en) 2012-11-12 2018-08-29 アイシーユー・メディカル・インコーポレーテッド Medical connector
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
CA2899000C (en) 2013-01-23 2022-07-12 Icu Medical, Inc. Pressure-regulating vial adaptors
EP2968894B1 (en) 2013-03-15 2017-07-19 ICU Medical, Inc. Medical connector
CA2918381C (en) 2013-07-19 2023-01-17 Icu Medical, Inc. Pressure-regulating fluid transfer systems and methods
CA2932124C (en) 2013-12-11 2023-05-09 Icu Medical, Inc. Check valve
WO2015119940A1 (en) 2014-02-04 2015-08-13 Icu Medical, Inc. Self-priming systems and methods
AU2015277135B2 (en) 2014-06-20 2020-02-20 Icu Medical, Inc. Pressure-regulating vial adaptors
USD786427S1 (en) 2014-12-03 2017-05-09 Icu Medical, Inc. Fluid manifold
USD793551S1 (en) 2014-12-03 2017-08-01 Icu Medical, Inc. Fluid manifold
USD802759S1 (en) * 2015-12-07 2017-11-14 Industrie Borla S.P.A. Injection site for medical fluid lines
AU201612887S (en) * 2015-12-07 2016-06-09 Borla Ind Connector for medical fluid lines
USD812743S1 (en) * 2015-12-07 2018-03-13 Industrie Borla S.P.A. Injection site for medical fluid lines
WO2017132588A1 (en) 2016-01-29 2017-08-03 Icu Medical, Inc. Pressure-regulating vial adaptors
CA172629S (en) * 2016-07-19 2017-09-12 Borla Ind Three-way dialyzer connector
IT201600075597A1 (en) * 2016-07-19 2018-01-19 Borla Ind FLOW COMPONENT PARTICULARLY FOR MEDICAL LINES FOR HEMODIALYSIS
EP3518860A4 (en) 2016-09-30 2020-06-10 ICU Medical, Inc. Pressure-regulating vial access devices and methods
DE102016013334B3 (en) * 2016-11-10 2018-04-05 Fresenius Medical Care Deutschland Gmbh Medical device with a connection piece for establishing a fluid connection between fluid-carrying lines
USD941465S1 (en) * 2019-10-30 2022-01-18 Industrie Borla S.P.A. Injection site
MX2022009203A (en) * 2020-01-27 2022-08-18 Becton Dickinson Co Rotating luer connector.

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5390898A (en) * 1994-04-06 1995-02-21 Habley Medical Technology Corporation Needleless dual direction check valve
US5465938A (en) * 1990-05-29 1995-11-14 Werge; Robert W. Universal fluid flow control
US5565938A (en) 1993-11-15 1996-10-15 Kabushiki Kaisha Topcon Ophthalmologic apparatus having improved display capability
IT1291508B1 (en) 1997-02-11 1999-01-11 Borla Ind LUER LOCH FITTING WITH PROTECTION CLOSURE.
EP1093828A2 (en) * 1999-10-20 2001-04-25 Industrie Borla SpA Anti-siphon valve for medical infusion lines and the like
WO2002004065A2 (en) * 2000-07-11 2002-01-17 Icu Medical, Inc. Medical valve with positive flow characteristics
EP1584346A1 (en) * 2003-01-09 2005-10-12 Fukai Kogyo Kabushiki Kaisha Seal valve, connection port, mix-feed tube, connection device for liquid infusion circuit, and connection system for liquid infusion circuit that are for medical device
EP1661599A1 (en) * 2004-11-24 2006-05-31 Industrie Borla SpA Flow component for medical infusion/transfusion lines
US20060149213A1 (en) * 2004-12-30 2006-07-06 John Raybuck Self-sealing male connector device with collapsible body

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045039U (en) * 1983-09-06 1985-03-29 テルモ株式会社 non-return valve
US5573516A (en) * 1995-09-18 1996-11-12 Medical Connexions, Inc. Needleless connector
US8377039B2 (en) * 2002-10-04 2013-02-19 Nxstage Medical, Inc. Injection site for male luer or other tubular connector
JP2006129884A (en) * 2004-11-02 2006-05-25 Kawasumi Lab Inc Mixed injection member, connection member and medical implement
US7879012B2 (en) * 2006-04-11 2011-02-01 Nypro Inc. Medical valve with resilient sealing member
JP2008005974A (en) * 2006-06-28 2008-01-17 Nippon Sherwood Medical Industries Ltd Lure fixing, fitting and connecting structure

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5465938A (en) * 1990-05-29 1995-11-14 Werge; Robert W. Universal fluid flow control
US5565938A (en) 1993-11-15 1996-10-15 Kabushiki Kaisha Topcon Ophthalmologic apparatus having improved display capability
US5390898A (en) * 1994-04-06 1995-02-21 Habley Medical Technology Corporation Needleless dual direction check valve
IT1291508B1 (en) 1997-02-11 1999-01-11 Borla Ind LUER LOCH FITTING WITH PROTECTION CLOSURE.
EP1093828A2 (en) * 1999-10-20 2001-04-25 Industrie Borla SpA Anti-siphon valve for medical infusion lines and the like
EP1093828B1 (en) 1999-10-20 2003-03-26 Industrie Borla SpA Anti-siphon valve for medical infusion lines and the like
WO2002004065A2 (en) * 2000-07-11 2002-01-17 Icu Medical, Inc. Medical valve with positive flow characteristics
EP1584346A1 (en) * 2003-01-09 2005-10-12 Fukai Kogyo Kabushiki Kaisha Seal valve, connection port, mix-feed tube, connection device for liquid infusion circuit, and connection system for liquid infusion circuit that are for medical device
EP1661599A1 (en) * 2004-11-24 2006-05-31 Industrie Borla SpA Flow component for medical infusion/transfusion lines
EP1661599B1 (en) 2004-11-24 2008-02-27 Industrie Borla SpA Flow component for medical infusion/transfusion lines
US20060149213A1 (en) * 2004-12-30 2006-07-06 John Raybuck Self-sealing male connector device with collapsible body

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2015146142A1 (en) * 2014-03-26 2017-04-13 テルモ株式会社 Connector and infusion set
EP3124071A4 (en) * 2014-03-26 2017-09-27 Terumo Kabushiki Kaisha Connector and infusion set
US10238858B2 (en) 2014-03-26 2019-03-26 Terumo Kabushiki Kaisha Connector and infusion set
WO2017074693A1 (en) * 2015-10-28 2017-05-04 Carefusion 303, Inc. Closed iv access device with y-port needle-free connector
US10758720B2 (en) 2015-10-28 2020-09-01 Carefusion 303, Inc. Closed IV access device with y-port needle-free connector
ITUB20155501A1 (en) * 2015-11-12 2017-05-12 Neovasc S R L CONNECTION DEVICE

Also Published As

Publication number Publication date
JP2015521933A (en) 2015-08-03
MX355592B (en) 2018-04-24
ZA201500235B (en) 2016-01-27
EP2869889B1 (en) 2022-02-23
ES2907458T3 (en) 2022-04-25
ITTO20120601A1 (en) 2014-01-10
PT2869889T (en) 2022-03-16
JP6470686B2 (en) 2019-02-13
HRP20220292T1 (en) 2022-05-27
SG11201500078UA (en) 2015-02-27
BR112015000200B1 (en) 2021-02-09
NZ703613A (en) 2016-06-24
DK2869889T3 (en) 2022-03-07
MX2015000111A (en) 2015-04-14
BR112015000200A2 (en) 2017-06-27
PL2869889T3 (en) 2022-04-04
AU2013288398B2 (en) 2017-11-09
US9585999B2 (en) 2017-03-07
RS63022B1 (en) 2022-04-29
US20150297817A1 (en) 2015-10-22
CN104602753A (en) 2015-05-06
EP2869889A1 (en) 2015-05-13
AU2013288398A1 (en) 2015-01-29
CN104602753B (en) 2018-01-19

Similar Documents

Publication Publication Date Title
EP2869889B1 (en) Flow system for medical lines
US11957872B2 (en) Deformable valve mechanism for controlling fluid delivery
JP2017504441A (en) Connector with built-in valve for medical line
EP1661599B1 (en) Flow component for medical infusion/transfusion lines
EP3010578B1 (en) Bidirectional valve with improved threshold pressure accuracy
CA2665722C (en) Valve connector for medical lines
US9586037B2 (en) Valved male luer connector
JP2008264030A (en) Valve connector for medical line
JP6382548B2 (en) Medical connector
KR20240152238A (en) Valve connector for medical lines

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13744817

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2013744817

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2015521088

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: MX/A/2015/000111

Country of ref document: MX

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 14413938

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2013288398

Country of ref document: AU

Date of ref document: 20130611

Kind code of ref document: A

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112015000200

Country of ref document: BR

ENP Entry into the national phase

Ref document number: 112015000200

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20150106