WO2014008901A2 - The use of artichoke for eradication of hepatitis c virus (hcv) - Google Patents

The use of artichoke for eradication of hepatitis c virus (hcv) Download PDF

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Publication number
WO2014008901A2
WO2014008901A2 PCT/EG2013/000009 EG2013000009W WO2014008901A2 WO 2014008901 A2 WO2014008901 A2 WO 2014008901A2 EG 2013000009 W EG2013000009 W EG 2013000009W WO 2014008901 A2 WO2014008901 A2 WO 2014008901A2
Authority
WO
WIPO (PCT)
Prior art keywords
hcv
eradication
hepatitis
virus
done
Prior art date
Application number
PCT/EG2013/000009
Other languages
Arabic (ar)
French (fr)
Other versions
WO2014008901A3 (en
Inventor
أحمد أحمد رزق السيد عطوية،
محمود فهمي السباعي،
Original Assignee
Atawia Ahmed Ahmed Rezk Elsaid
Elsebai Mahmoud Fahmi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atawia Ahmed Ahmed Rezk Elsaid, Elsebai Mahmoud Fahmi filed Critical Atawia Ahmed Ahmed Rezk Elsaid
Publication of WO2014008901A2 publication Critical patent/WO2014008901A2/en
Publication of WO2014008901A3 publication Critical patent/WO2014008901A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a discovery of a significant biological activity of the Artichokes for the eradication of hepatitis C virus (HCV). Within short time and without side effects, the water extract of the globe Artichoke plant showed complete eradication of HCV. The biological evaluation was done on Egyptian volunteer patients infected with HCV. The monitoring of analysis was done through PCR before and after phytotherapy. In addition, the extract cured ascites, jaundice and normalized the liver enzymes SGPT & SGOT and showed significant activity against acne, obesity, diabetes, and has digestive effect and vermifuge. The dosage forms are capsules, tablets and syrups. The used parts of the plant are leaves, roots, seeds and/or flowers.
PCT/EG2013/000009 2012-06-27 2013-04-23 The use of artichoke for eradication of hepatitis c virus (hcv) WO2014008901A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EG2012061188 2012-06-27
EG2012061188 2012-06-27

Publications (2)

Publication Number Publication Date
WO2014008901A2 true WO2014008901A2 (en) 2014-01-16
WO2014008901A3 WO2014008901A3 (en) 2014-03-13

Family

ID=49916600

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EG2013/000009 WO2014008901A2 (en) 2012-06-27 2013-04-23 The use of artichoke for eradication of hepatitis c virus (hcv)

Country Status (1)

Country Link
WO (1) WO2014008901A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016169573A1 (en) * 2015-04-20 2016-10-27 Elsebai Mahmoud Fahmi Sesquiterpene lactones as potent and broad spectrum antiviral compounds against all genotypes of hepatitis c virus (hcv)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020012708A1 (en) * 1996-07-06 2002-01-31 Arr Pharma Use of artichoke (cynara) extracts
US20040234674A1 (en) * 2001-08-08 2004-11-25 Jurgen Eich Artichoke leaf extracts
RU2281112C2 (en) * 2004-05-12 2006-08-10 Общество С Ограниченной Ответственностью "Фарм-Стом" Method for production of hepatothropic artichoke extract-based polyphenol pharmaceutical agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020012708A1 (en) * 1996-07-06 2002-01-31 Arr Pharma Use of artichoke (cynara) extracts
US20040234674A1 (en) * 2001-08-08 2004-11-25 Jurgen Eich Artichoke leaf extracts
RU2281112C2 (en) * 2004-05-12 2006-08-10 Общество С Ограниченной Ответственностью "Фарм-Стом" Method for production of hepatothropic artichoke extract-based polyphenol pharmaceutical agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016169573A1 (en) * 2015-04-20 2016-10-27 Elsebai Mahmoud Fahmi Sesquiterpene lactones as potent and broad spectrum antiviral compounds against all genotypes of hepatitis c virus (hcv)

Also Published As

Publication number Publication date
WO2014008901A3 (en) 2014-03-13

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