WO2013192242A3 - Cell surface marker and methods of use thereof - Google Patents

Cell surface marker and methods of use thereof Download PDF

Info

Publication number
WO2013192242A3
WO2013192242A3 PCT/US2013/046436 US2013046436W WO2013192242A3 WO 2013192242 A3 WO2013192242 A3 WO 2013192242A3 US 2013046436 W US2013046436 W US 2013046436W WO 2013192242 A3 WO2013192242 A3 WO 2013192242A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
cell surface
surface marker
biomarkers
gctm
Prior art date
Application number
PCT/US2013/046436
Other languages
French (fr)
Other versions
WO2013192242A2 (en
Inventor
Martin Pera
Jun Wu
David BRAXTON
Kouichi Hasegawa
Veronika AKOPIAN
Original Assignee
University Of Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Southern California filed Critical University Of Southern California
Publication of WO2013192242A2 publication Critical patent/WO2013192242A2/en
Publication of WO2013192242A3 publication Critical patent/WO2013192242A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

The present invention provides biomarkers comprising GCTM-5 antigen for detection and screening of cancer, as well as a distinct population of cells identified by the expression pattern of GCTM-5, diagnostic methods for utilizing the biomarkers and reagents for detecting the biomarkers.
PCT/US2013/046436 2012-06-18 2013-06-18 Cell surface marker and methods of use thereof WO2013192242A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261661259P 2012-06-18 2012-06-18
US61/661,259 2012-06-18

Publications (2)

Publication Number Publication Date
WO2013192242A2 WO2013192242A2 (en) 2013-12-27
WO2013192242A3 true WO2013192242A3 (en) 2014-03-20

Family

ID=49769679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/046436 WO2013192242A2 (en) 2012-06-18 2013-06-18 Cell surface marker and methods of use thereof

Country Status (1)

Country Link
WO (1) WO2013192242A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190072557A1 (en) * 2014-11-17 2019-03-07 The University Of Queensland Glycoprotein biomarkers for esophageal adenocarcinoma and barrett's esophagus and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009492A1 (en) * 2002-07-10 2004-01-15 Mi-Kyung Kim Multiplex PCR primer set for human glucokinase gene amplification
WO2004099432A2 (en) * 2003-05-02 2004-11-18 The Johns Hopkins University Identification of biomarkers for detecting pancreatic cancer
US20070218059A1 (en) * 2003-10-09 2007-09-20 Martin Pera Cell Surface Marker
US20080286284A1 (en) * 2001-10-23 2008-11-20 Psma Development Company, Llc Compositions of PSMA antibodies

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080286284A1 (en) * 2001-10-23 2008-11-20 Psma Development Company, Llc Compositions of PSMA antibodies
US20040009492A1 (en) * 2002-07-10 2004-01-15 Mi-Kyung Kim Multiplex PCR primer set for human glucokinase gene amplification
WO2004099432A2 (en) * 2003-05-02 2004-11-18 The Johns Hopkins University Identification of biomarkers for detecting pancreatic cancer
US20070218059A1 (en) * 2003-10-09 2007-09-20 Martin Pera Cell Surface Marker

Also Published As

Publication number Publication date
WO2013192242A2 (en) 2013-12-27

Similar Documents

Publication Publication Date Title
WO2012021887A3 (en) Biomarkers for the early detection of breast cancer
WO2012047618A3 (en) Mesothelioma biomarkers and uses thereof
WO2014071358A3 (en) Novel ntrk1 fusion molecules and uses thereof
IL256307B (en) Methods and systems for detecting an analyte or classifying a sample
EA201590027A1 (en) DETECTION METHODS OF DISEASES OR CONDITIONS
WO2012012725A3 (en) Methods of detecting diseases or conditions using phagocytic cells
WO2011153254A3 (en) Prostate cancer associated circulating nucleic acid biomarkers
WO2012096545A3 (en) Novel pancreatic cancer biomarker using the characteristics of pancreatic cancer stem cells, and use thereof
IL235717A0 (en) Interrogatory cell-based assays for identifying drug-induced toxicity markers
WO2013106844A3 (en) Methods and compositions for the treatment and diaginosis of pancreatic cancer
WO2014058760A3 (en) Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making
EP3665187A4 (en) Assay methods for improved analyte detection
WO2012074904A3 (en) Methods and systems for evaluating the sensitivity or resistance of tumor specimens to chemotherapeutic agents
NZ606725A (en) Methods for predicting anti-cancer response
WO2014041185A3 (en) Colon cancer diagnostic method and means
EP2281903A4 (en) Cancer marker, method for evaluation of cancer by using the cancer marker, and evaluation reagent
EP3176268A4 (en) Novel biomarker for predicting sensitivity to egfr-targeting agent, and use thereof
WO2011112845A3 (en) Methods and compositions related to a multi-methylation assay to predict patient outcome
WO2012170206A3 (en) Color-producing diagnostic systems, reagents and methods
WO2009055823A3 (en) Method to predict responsiveness of breast cancer to polyaminetype chemotherapy
WO2012082742A3 (en) Detecting cancer with anti-ccl25 and anti-ccr9 antibodies
WO2013028807A3 (en) Renal cell carcinoma biomarkers and uses thereof
EP3054298A4 (en) Method for detecting pancreatic tumor, antibody, and pancreatic tumor detection kit
WO2013124738A3 (en) Methods and biomarkers for detection and prognosis of cervical cancer
EP3385717A3 (en) Methods of detecting prostate cancer

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13807646

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 13807646

Country of ref document: EP

Kind code of ref document: A2