WO2013175395A3 - Procédé amélioré pour la préparation de saxagliptine et de ses sels - Google Patents
Procédé amélioré pour la préparation de saxagliptine et de ses sels Download PDFInfo
- Publication number
- WO2013175395A3 WO2013175395A3 PCT/IB2013/054167 IB2013054167W WO2013175395A3 WO 2013175395 A3 WO2013175395 A3 WO 2013175395A3 IB 2013054167 W IB2013054167 W IB 2013054167W WO 2013175395 A3 WO2013175395 A3 WO 2013175395A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- saxagliptin
- salts
- preparation
- improved process
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Abstract
La présente invention concerne des procédés améliorés de préparation de saxagliptine ou de son sel et des intermédiaires correspondants.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2012/CHE/2012 | 2012-05-21 | ||
IN2012CH2012 | 2012-05-21 | ||
IN250CH2013 | 2013-01-18 | ||
IN250/CHE/2013 | 2013-01-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013175395A2 WO2013175395A2 (fr) | 2013-11-28 |
WO2013175395A3 true WO2013175395A3 (fr) | 2014-01-30 |
Family
ID=49624449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2013/054167 WO2013175395A2 (fr) | 2012-05-21 | 2013-05-21 | Procédé amélioré pour la préparation de saxagliptine et de ses sels |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2013175395A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104109100A (zh) * | 2014-05-29 | 2014-10-22 | 上海应用技术学院 | 一种金刚烷氨基酸酯化合物的合成方法 |
CN105315189A (zh) * | 2014-05-29 | 2016-02-10 | 上海医药工业研究院 | 一种制备(5s)-5-氨基羰基-4,5-二氢-1h-吡咯-1-羧酸-1(1,1-二甲基乙基)酯的方法 |
CN104098487A (zh) * | 2014-07-31 | 2014-10-15 | 天津民祥生物医药科技有限公司 | 一种n-叔丁氧羰基-3-羟基-1-金刚烷基甘氨酸的制备方法 |
CN105503698A (zh) * | 2014-09-26 | 2016-04-20 | 深圳翰宇药业股份有限公司 | 一种合成沙格列汀及其中间体的方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004052850A2 (fr) * | 2002-12-09 | 2004-06-24 | Bristol-Myers Squibb Company | Procedes et composes pour produire des inhibiteurs de la dipeptidyle-peptidase et leurs intermediaires |
WO2006020664A2 (fr) * | 2004-08-11 | 2006-02-23 | Bristol-Myers Squibb Company | Procede d'ammonolyse destine a la preparation d'intermediaires pour des inhibiteurs iv dpp |
-
2013
- 2013-05-21 WO PCT/IB2013/054167 patent/WO2013175395A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004052850A2 (fr) * | 2002-12-09 | 2004-06-24 | Bristol-Myers Squibb Company | Procedes et composes pour produire des inhibiteurs de la dipeptidyle-peptidase et leurs intermediaires |
WO2006020664A2 (fr) * | 2004-08-11 | 2006-02-23 | Bristol-Myers Squibb Company | Procede d'ammonolyse destine a la preparation d'intermediaires pour des inhibiteurs iv dpp |
Non-Patent Citations (2)
Title |
---|
LIU K. K. -C. ET AL.: "Synthetic approaches to the 2009 new drugs", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19, 2011, pages 1136 - 1154 * |
SAVAGE S. A. ET AL.: "Preparation of Saxagliptin, a Novel DPP-IV Inhibitor", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 13, 2009, pages 1169 - 1176 * |
Also Published As
Publication number | Publication date |
---|---|
WO2013175395A2 (fr) | 2013-11-28 |
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