WO2013172866A3 - Sensors for detection of mesothelin - Google Patents

Sensors for detection of mesothelin Download PDF

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Publication number
WO2013172866A3
WO2013172866A3 PCT/US2012/068589 US2012068589W WO2013172866A3 WO 2013172866 A3 WO2013172866 A3 WO 2013172866A3 US 2012068589 W US2012068589 W US 2012068589W WO 2013172866 A3 WO2013172866 A3 WO 2013172866A3
Authority
WO
WIPO (PCT)
Prior art keywords
mesothelin
sensor
sensors
detection
sample
Prior art date
Application number
PCT/US2012/068589
Other languages
French (fr)
Other versions
WO2013172866A2 (en
Inventor
Jack Thomas ANDRAKA
Original Assignee
Andraka Jack Thomas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andraka Jack Thomas filed Critical Andraka Jack Thomas
Publication of WO2013172866A2 publication Critical patent/WO2013172866A2/en
Publication of WO2013172866A3 publication Critical patent/WO2013172866A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A sensor for detection of mesothelin in a sample is disclosed, as well as methods of making the sensor and methods of its use. In particular, the sensor is useful for screening patients for cancers that overexpress mesothelin. Additionally, a sensor able to detect a molecule of interest in a sample, such as a biological sample or an environmental sample, and a method of making such sensors are disclosed.
PCT/US2012/068589 2012-05-12 2012-12-07 Sensors for detection of mesothelin WO2013172866A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261632838P 2012-05-12 2012-05-12
US61/632,838 2012-05-12
US201261656988P 2012-06-07 2012-06-07
US61/656,988 2012-06-07

Publications (2)

Publication Number Publication Date
WO2013172866A2 WO2013172866A2 (en) 2013-11-21
WO2013172866A3 true WO2013172866A3 (en) 2014-01-23

Family

ID=49584421

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/068589 WO2013172866A2 (en) 2012-05-12 2012-12-07 Sensors for detection of mesothelin

Country Status (1)

Country Link
WO (1) WO2013172866A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190154670A1 (en) * 2016-05-10 2019-05-23 Memorial Sloan Kettering Cancer Center Swcnt-dna-antibody conjugates, related compositions, and systems, methods and devices for their use
CN109900914A (en) * 2019-03-12 2019-06-18 西安交通大学 A detection method of paper-based sensor based on specific CA19-9 antibody
PL447285A1 (en) * 2023-12-27 2025-06-30 Uniwersytet W Białymstoku Biosensor for mesothelin determination using matrix surface plasmon resonance technique in Imaging version

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100022026A1 (en) * 2008-06-20 2010-01-28 Armin Rump Methods, kits, reagents and devices for detecting mesothelin and/or megakaryocyte potentiating factor in peritoneal fluids
US7824925B2 (en) * 1995-03-10 2010-11-02 Meso Scale Technology Llp Multi-array, multi-specific electrochemiluminescence testing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7824925B2 (en) * 1995-03-10 2010-11-02 Meso Scale Technology Llp Multi-array, multi-specific electrochemiluminescence testing
US20100022026A1 (en) * 2008-06-20 2010-01-28 Armin Rump Methods, kits, reagents and devices for detecting mesothelin and/or megakaryocyte potentiating factor in peritoneal fluids

Also Published As

Publication number Publication date
WO2013172866A2 (en) 2013-11-21

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