WO2013156222A3 - Method for generating perfusion images from diffusion weighted data - Google Patents

Method for generating perfusion images from diffusion weighted data Download PDF

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Publication number
WO2013156222A3
WO2013156222A3 PCT/EP2013/055424 EP2013055424W WO2013156222A3 WO 2013156222 A3 WO2013156222 A3 WO 2013156222A3 EP 2013055424 W EP2013055424 W EP 2013055424W WO 2013156222 A3 WO2013156222 A3 WO 2013156222A3
Authority
WO
WIPO (PCT)
Prior art keywords
data
perfusion
images
weighted data
human brain
Prior art date
Application number
PCT/EP2013/055424
Other languages
French (fr)
Other versions
WO2013156222A2 (en
Inventor
Christian FEDERAU
Patric HAGMANN
Philippe Maeder
Original Assignee
Centre Hospitalier Universitaire Vaudois (Chuv)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Hospitalier Universitaire Vaudois (Chuv) filed Critical Centre Hospitalier Universitaire Vaudois (Chuv)
Publication of WO2013156222A2 publication Critical patent/WO2013156222A2/en
Publication of WO2013156222A3 publication Critical patent/WO2013156222A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56366—Perfusion imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

There is presented a method for generating one or more images indicative of perfusion in a human brain, the method comprising obtaining a first set of data corresponding to spatially resolved diffusion weighted data, calculating a second set of data corresponding to spatially resolved perfusion weighted data, such as intravoxel incoherent motion parameters, from the first set of data, providing the one or more images indicative of perfusion in the human brain, the images being based on the second set of data. In a more specific embodiment, the invention further relates to determining clinically relevant areas within the human brain, such as tumour. An advantage may be that obtaining one or more perfusion weighted images from the human brain may be realized by measuring diffusion weighted data and calculating the perfusion weighted data therefrom.
PCT/EP2013/055424 2012-04-16 2013-03-15 Method for generating perfusion images WO2013156222A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261624655P 2012-04-16 2012-04-16
US61/624,655 2012-04-16
EP13153301 2013-01-30
EP13153301.0 2013-01-30

Publications (2)

Publication Number Publication Date
WO2013156222A2 WO2013156222A2 (en) 2013-10-24
WO2013156222A3 true WO2013156222A3 (en) 2013-12-19

Family

ID=47709895

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2013/055424 WO2013156222A2 (en) 2012-04-16 2013-03-15 Method for generating perfusion images

Country Status (1)

Country Link
WO (1) WO2013156222A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2695758C1 (en) * 2018-06-04 2019-07-25 Федеральное государственное бюджетное образовательное учреждение высшего образования Иркутский государственный медицинский университет Министерства здравоохранения Российской Федерации Method for prediction of clinical course in patients with brain metastases
CN112862916B (en) * 2021-03-11 2021-09-10 首都医科大学附属北京天坛医院 CT perfusion function map quantitative parameter processing equipment and method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060241375A1 (en) * 2003-03-31 2006-10-26 Van Den Brink Johan S Method of magnetic resonance perfusion imaging

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060241375A1 (en) * 2003-03-31 2006-10-26 Van Den Brink Johan S Method of magnetic resonance perfusion imaging

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
A. LUCIANI ET AL: "Liver Cirrhosis: Intravoxel Incoherent Motion MR Imaging - Pilot Study", RADIOLOGY, vol. 249, no. 3, 14 November 2008 (2008-11-14), pages 891 - 899, XP055063703, ISSN: 0033-8419, DOI: 10.1148/radiol.2493080080 *
ANDREAS LEMKE ET AL: "Toward an optimal distribution ofvalues for intravoxel incoherent motion imaging", MAGNETIC RESONANCE IMAGING, ELSEVIER SCIENCE, TARRYTOWN, NY, US, vol. 29, no. 6, 7 March 2011 (2011-03-07), pages 766 - 776, XP028378884, ISSN: 0730-725X, [retrieved on 20110401], DOI: 10.1016/J.MRI.2011.03.004 *
BIHAN LE D ET AL: "MR IMAGING OF INTRAVOXEL INCOHERENT MOTIONS: APPLICATION TO DIFFUSION AND PERFUSION IN NEUROLOGIC DISORDERS", RADIOLOGY, RADIOLOGICAL SOCIETY OF NORTH AMERICA, OAK BROOK,IL, US, vol. 161, 1 January 1986 (1986-01-01), pages 401 - 407, XP009043109, ISSN: 0033-8419 *
BIHAN LE D ET AL: "SEPARATION OF DIFFUSION AND PERFUSION IN INTRAVOXEL INCOHERENT MOTION MR IMAGING", RADIOLOGY, RADIOLOGICAL SOCIETY OF NORTH AMERICA, OAK BROOK,IL, US, vol. 168, no. 2, 1 January 1988 (1988-01-01), pages 497 - 505, XP009033363, ISSN: 0033-8419 *
CALLOT V ET AL: "IVIM-based MRI method to study the microcirculation in the heart: preliminary results in dogs", PROCEEDINGS OF SPIE, S P I E - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, US, vol. 5031, 1 January 2003 (2003-01-01), pages 214 - 221, XP002287611, ISSN: 0277-786X, DOI: 10.1117/12.480284 *
DENIS LE BIHAN ET AL: "The Capillary Network: A Link between IVIM and Classical Perfusion", MAGNETIC RESONANCE IN MEDICINE, vol. 27, no. 1, 1 September 1992 (1992-09-01), pages 171 - 178, XP055063724, DOI: 10.1002/mrm.1910270116 *
MOORE R J ET AL: "In vivo intravoxel incoherent motion measurements in the human placenta using echo-planar imaging at 0.5 T", MAGNETIC RESONANCE IN MEDICINE, ACADEMIC PRESS, DULUTH, MN, US, vol. 43, no. 2, 1 February 2000 (2000-02-01), pages 295 - 302, XP002287612, ISSN: 0740-3194, DOI: 10.1002/(SICI)1522-2594(200002)43:2<295::AID-MRM18>3.0.CO;2-2 *

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