WO2013144976A3 - Chewable soft gelatin capsule dosage form of mucolytic agents - Google Patents

Chewable soft gelatin capsule dosage form of mucolytic agents Download PDF

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Publication number
WO2013144976A3
WO2013144976A3 PCT/IN2013/000167 IN2013000167W WO2013144976A3 WO 2013144976 A3 WO2013144976 A3 WO 2013144976A3 IN 2013000167 W IN2013000167 W IN 2013000167W WO 2013144976 A3 WO2013144976 A3 WO 2013144976A3
Authority
WO
WIPO (PCT)
Prior art keywords
dosage form
gelatin capsule
mucolytic agents
soft gelatin
capsule dosage
Prior art date
Application number
PCT/IN2013/000167
Other languages
French (fr)
Other versions
WO2013144976A2 (en
Inventor
Chandanmal pukhraj BOTHRA
Shesha Iyengar SHRINIVASAN
Kandarapu Raghupathi
Maram SAMBASIVA RAO
Original Assignee
Medreich Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medreich Limited filed Critical Medreich Limited
Publication of WO2013144976A2 publication Critical patent/WO2013144976A2/en
Publication of WO2013144976A3 publication Critical patent/WO2013144976A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A chewable soft gelatin capsule dosage form of mucolytic agents. The mucolytic agents are selected from acetylcysteine, erdosteine, bromheksin, carbocisteine and guiafenesin or pharmaceutically acceptable salts thereof.
PCT/IN2013/000167 2012-03-28 2013-03-18 Chewable soft gelatin capsule dosage form of mucolytic agents WO2013144976A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1161/CHE/2012 2012-03-28
IN1161CH2012 2012-03-28

Publications (2)

Publication Number Publication Date
WO2013144976A2 WO2013144976A2 (en) 2013-10-03
WO2013144976A3 true WO2013144976A3 (en) 2013-12-05

Family

ID=49261354

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2013/000167 WO2013144976A2 (en) 2012-03-28 2013-03-18 Chewable soft gelatin capsule dosage form of mucolytic agents

Country Status (1)

Country Link
WO (1) WO2013144976A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201723198A2 (en) * 2017-12-30 2019-07-22 Neutec Ar Ge Sanayi Ve Ticaret Anonim Sirketi Compositions containing Erdosteine and ascorbic acid.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
WO2006102157A1 (en) * 2005-03-21 2006-09-28 Ivax Pharmaceuticals S.R.O. Crystallization inhibitor and its use in gelatin capsules
US20070049641A1 (en) * 2005-08-24 2007-03-01 Rabindra Tirouvanziam Methods for treating and monitoring inflammation and redox imbalance cystic fibrosis
CN101612154A (en) * 2008-06-23 2009-12-30 广东肇庆星湖生物科技股份有限公司 Contain the compositions of pivampicillin and preparation method, purposes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
WO2006102157A1 (en) * 2005-03-21 2006-09-28 Ivax Pharmaceuticals S.R.O. Crystallization inhibitor and its use in gelatin capsules
US20070049641A1 (en) * 2005-08-24 2007-03-01 Rabindra Tirouvanziam Methods for treating and monitoring inflammation and redox imbalance cystic fibrosis
CN101612154A (en) * 2008-06-23 2009-12-30 广东肇庆星湖生物科技股份有限公司 Contain the compositions of pivampicillin and preparation method, purposes

Also Published As

Publication number Publication date
WO2013144976A2 (en) 2013-10-03

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