WO2013112488A3 - Dermal filling compositions and methods - Google Patents

Dermal filling compositions and methods Download PDF

Info

Publication number
WO2013112488A3
WO2013112488A3 PCT/US2013/022592 US2013022592W WO2013112488A3 WO 2013112488 A3 WO2013112488 A3 WO 2013112488A3 US 2013022592 W US2013022592 W US 2013022592W WO 2013112488 A3 WO2013112488 A3 WO 2013112488A3
Authority
WO
WIPO (PCT)
Prior art keywords
dermal
penetrating peptide
cell penetrating
methods
pharmacological
Prior art date
Application number
PCT/US2013/022592
Other languages
French (fr)
Other versions
WO2013112488A2 (en
Inventor
Keith LEONARD
Serge Lichtsteiner
Original Assignee
Kythera Biopharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kythera Biopharmaceuticals, Inc. filed Critical Kythera Biopharmaceuticals, Inc.
Publication of WO2013112488A2 publication Critical patent/WO2013112488A2/en
Publication of WO2013112488A3 publication Critical patent/WO2013112488A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/001—Preparations for care of the lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Provided are compositions and methods for filling cells with non-pharmacological dermal fillers leading to smoothened skin wrinkles, augmented lips, improved skin appearance, or treated scars. Additionally, the present disclosure provides a composition comprising a non-pharmacological dermal filler and optionally a pharmaceutically acceptable excipient, the dermal filler being covalently or non-covalently bound to a cell penetrating peptide that is capable to penetrate a dermal cell. In one aspect, the cell penetrating peptide is not longer than about 10 amino acids in length. In another aspect, the cell penetrating peptide is about 7 amino acids in length. In some aspects, the cell penetrating peptide is capable to deliver the dermal filler across a stratum corneum
PCT/US2013/022592 2012-01-23 2013-01-22 Dermal filling compositions and methods WO2013112488A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261589775P 2012-01-23 2012-01-23
US61/589,775 2012-01-23
US201261604396P 2012-02-28 2012-02-28
US61/604,396 2012-02-28

Publications (2)

Publication Number Publication Date
WO2013112488A2 WO2013112488A2 (en) 2013-08-01
WO2013112488A3 true WO2013112488A3 (en) 2015-06-11

Family

ID=48874055

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/022592 WO2013112488A2 (en) 2012-01-23 2013-01-22 Dermal filling compositions and methods

Country Status (1)

Country Link
WO (1) WO2013112488A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9642895B2 (en) 2013-08-12 2017-05-09 3M Innovative Properties Company Peptides for enhancing transdermal delivery
US20180251495A1 (en) * 2015-09-15 2018-09-06 The Regents Of The University Of California Skin-Penetrating Peptides and Compositions and Methods of Use Thereof
CN114470329A (en) * 2022-03-11 2022-05-13 上海医妃医药科技有限公司 Human albumin dermal filler

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115052A2 (en) * 2009-04-03 2010-10-07 The Mclean Hospital Corporation Induced pluripotent stem cells
US20120128756A1 (en) * 2010-11-09 2012-05-24 Tracy Hsu Skin Permeating And Cell Entering (SPACE) Peptides and Methods of Use Thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115052A2 (en) * 2009-04-03 2010-10-07 The Mclean Hospital Corporation Induced pluripotent stem cells
US20120128756A1 (en) * 2010-11-09 2012-05-24 Tracy Hsu Skin Permeating And Cell Entering (SPACE) Peptides and Methods of Use Thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HSU ET AL.: "Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 108, no. 11, 20 September 2011 (2011-09-20), pages 15816 - 15821 *

Also Published As

Publication number Publication date
WO2013112488A2 (en) 2013-08-01

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