WO2013111136A3 - Selective reduction of nerve activity - Google Patents

Selective reduction of nerve activity Download PDF

Info

Publication number
WO2013111136A3
WO2013111136A3 PCT/IL2013/050068 IL2013050068W WO2013111136A3 WO 2013111136 A3 WO2013111136 A3 WO 2013111136A3 IL 2013050068 W IL2013050068 W IL 2013050068W WO 2013111136 A3 WO2013111136 A3 WO 2013111136A3
Authority
WO
WIPO (PCT)
Prior art keywords
selective reduction
nerve activity
renal
target level
norepinephrine levels
Prior art date
Application number
PCT/IL2013/050068
Other languages
French (fr)
Other versions
WO2013111136A2 (en
Inventor
Ariel Sverdlik
Avital Schauder
Original Assignee
CardioSonic Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CardioSonic Ltd. filed Critical CardioSonic Ltd.
Publication of WO2013111136A2 publication Critical patent/WO2013111136A2/en
Publication of WO2013111136A3 publication Critical patent/WO2013111136A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00404—Blood vessels other than those in or around the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434—Neural system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505—Urinary tract
    • A61B2018/00511—Kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1861—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method of selectively reducing renal norepinephrine levels in an animal or human, said method comprising selecting a norepinephrine target level and applying energy to one or more renal nerves in an amount which is sufficient to reduce renal norepinephrine levels to said selected target level within about +/- 30%. Devices for selectively reducing renal norepinephrine levels are also described.
PCT/IL2013/050068 2012-01-25 2013-01-24 Selective reduction of nerve activity WO2013111136A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261590423P 2012-01-25 2012-01-25
US61/590,423 2012-01-25

Publications (2)

Publication Number Publication Date
WO2013111136A2 WO2013111136A2 (en) 2013-08-01
WO2013111136A3 true WO2013111136A3 (en) 2013-11-14

Family

ID=48874025

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2013/050068 WO2013111136A2 (en) 2012-01-25 2013-01-24 Selective reduction of nerve activity

Country Status (1)

Country Link
WO (1) WO2013111136A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
WO2007140331A2 (en) 2006-05-25 2007-12-06 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
US9566456B2 (en) 2010-10-18 2017-02-14 CardioSonic Ltd. Ultrasound transceiver and cooling thereof
US9028417B2 (en) 2010-10-18 2015-05-12 CardioSonic Ltd. Ultrasound emission element
JP2013543423A (en) 2010-10-18 2013-12-05 カーディオソニック リミテッド Tissue treatment
US8696581B2 (en) 2010-10-18 2014-04-15 CardioSonic Ltd. Ultrasound transducer and uses thereof
SG11201402610QA (en) 2011-12-09 2014-10-30 Metavention Inc Therapeutic neuromodulation of the hepatic system
US10357304B2 (en) 2012-04-18 2019-07-23 CardioSonic Ltd. Tissue treatment
US11357447B2 (en) 2012-05-31 2022-06-14 Sonivie Ltd. Method and/or apparatus for measuring renal denervation effectiveness
CN104902836B (en) 2012-11-05 2017-08-08 毕达哥拉斯医疗有限公司 Controlled tissue melts
US9770593B2 (en) 2012-11-05 2017-09-26 Pythagoras Medical Ltd. Patient selection using a transluminally-applied electric current
WO2014188430A2 (en) 2013-05-23 2014-11-27 CardioSonic Ltd. Devices and methods for renal denervation and assessment thereof
WO2015170281A1 (en) 2014-05-07 2015-11-12 Rainbow Medical Ltd Controlled tissue ablation techniques
US10383685B2 (en) 2015-05-07 2019-08-20 Pythagoras Medical Ltd. Techniques for use with nerve tissue
WO2017199240A2 (en) 2016-05-18 2017-11-23 Pythagoras Medical Ltd. Helical catheter
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
US11318331B2 (en) 2017-03-20 2022-05-03 Sonivie Ltd. Pulmonary hypertension treatment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080300655A1 (en) * 2007-05-31 2008-12-04 Pacesetter, Inc. Techniques to monitor and trend nerve damage and recovery
US20110092880A1 (en) * 2009-10-12 2011-04-21 Michael Gertner Energetic modulation of nerves
US7940969B2 (en) * 2002-08-26 2011-05-10 The Cleveland Clinic Foundation System and method of characterizing vascular tissue
US20110112400A1 (en) * 2009-11-06 2011-05-12 Ardian, Inc. High intensity focused ultrasound catheter apparatuses, systems, and methods for renal neuromodulation
US20110264086A1 (en) * 2010-04-14 2011-10-27 Frank Ingle Renal artery denervation apparatus employing helical shaping arrangement

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7940969B2 (en) * 2002-08-26 2011-05-10 The Cleveland Clinic Foundation System and method of characterizing vascular tissue
US20080300655A1 (en) * 2007-05-31 2008-12-04 Pacesetter, Inc. Techniques to monitor and trend nerve damage and recovery
US20110092880A1 (en) * 2009-10-12 2011-04-21 Michael Gertner Energetic modulation of nerves
US20110112400A1 (en) * 2009-11-06 2011-05-12 Ardian, Inc. High intensity focused ultrasound catheter apparatuses, systems, and methods for renal neuromodulation
US20110264086A1 (en) * 2010-04-14 2011-10-27 Frank Ingle Renal artery denervation apparatus employing helical shaping arrangement

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DIBONA ET AL.: "'Translational medicine: the antihypertensive effect of renal denervation", AMERICAN JOURNAL OF PHYSIOL REGUL INTEGR COMP PHYSIOL, vol. 289, 2 December 2009 (2009-12-02), pages R245 - R253 *
LIN ET AL.: "Utility of the PlasmaKineticTM Bipolar Forceps@ for Control of the Renal Artery in a Porcine Model", JTUA, vol. 14, no. 3, September 2003 (2003-09-01), pages 118 - 121 *

Also Published As

Publication number Publication date
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