WO2013105105A3 - Nouvelles compositions de vaccins viraux et méthodes de préparation de tels vaccins - Google Patents

Nouvelles compositions de vaccins viraux et méthodes de préparation de tels vaccins Download PDF

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Publication number
WO2013105105A3
WO2013105105A3 PCT/IN2012/000701 IN2012000701W WO2013105105A3 WO 2013105105 A3 WO2013105105 A3 WO 2013105105A3 IN 2012000701 W IN2012000701 W IN 2012000701W WO 2013105105 A3 WO2013105105 A3 WO 2013105105A3
Authority
WO
WIPO (PCT)
Prior art keywords
vaccines
preparing
methods
vaccine compositions
viral vaccine
Prior art date
Application number
PCT/IN2012/000701
Other languages
English (en)
Other versions
WO2013105105A2 (fr
Inventor
Rajeev Mhalasakant DHERE
Jagdish Kamalaji ZADE
Rajendra Narayan SABALE
Original Assignee
Serum Institute Of India Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serum Institute Of India Ltd. filed Critical Serum Institute Of India Ltd.
Publication of WO2013105105A2 publication Critical patent/WO2013105105A2/fr
Publication of WO2013105105A3 publication Critical patent/WO2013105105A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12311—Rotavirus, e.g. rotavirus A
    • C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne un procédé nouveau et économique de concentration de rotavirus pour obtenir des compositions liquides rotavirales adsorbées sur gel, le titre viral après adsorption étant au moins 10 fois supérieur au titre viral avant adsorption avec élimination partielle de contaminants d'acides nucléiques. La présente invention concerne également des formulations vaccinales stables d'un tel rotavirus inactivé et vivant.
PCT/IN2012/000701 2012-01-13 2012-10-25 Nouvelles compositions de vaccins viraux et méthodes de préparation de tels vaccins WO2013105105A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN135MU2012 2012-01-13
IN135/MUM/2012 2012-01-13

Publications (2)

Publication Number Publication Date
WO2013105105A2 WO2013105105A2 (fr) 2013-07-18
WO2013105105A3 true WO2013105105A3 (fr) 2013-09-06

Family

ID=48782017

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000701 WO2013105105A2 (fr) 2012-01-13 2012-10-25 Nouvelles compositions de vaccins viraux et méthodes de préparation de tels vaccins

Country Status (1)

Country Link
WO (1) WO2013105105A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115011566B (zh) * 2022-05-25 2024-01-23 辽宁成大生物股份有限公司 一种人用狂犬病疫苗中残留dna的去除方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294071A2 (fr) * 1987-06-03 1988-12-07 Merck & Co. Inc. Vaccins contre l'hépatite B comprenant des gels préfabriqués d'hydroxyde d'aluminium et leurs procédés de fabrication
WO2006087205A1 (fr) * 2005-02-17 2006-08-24 Glaxosmithkline Biologicals S.A. Vaccin a base de rotavirus vivant attenue pour administration orale
US20100068227A1 (en) * 2006-05-12 2010-03-18 Krishna Murthy Ella Composition Useful as a Vaccine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294071A2 (fr) * 1987-06-03 1988-12-07 Merck & Co. Inc. Vaccins contre l'hépatite B comprenant des gels préfabriqués d'hydroxyde d'aluminium et leurs procédés de fabrication
WO2006087205A1 (fr) * 2005-02-17 2006-08-24 Glaxosmithkline Biologicals S.A. Vaccin a base de rotavirus vivant attenue pour administration orale
US20100068227A1 (en) * 2006-05-12 2010-03-18 Krishna Murthy Ella Composition Useful as a Vaccine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SABIN: "Experiments of the purification and concentration of the virus poliomyelitis", JOURNAL EXP. MED., vol. 56, no. 3, 31 August 1932 (1932-08-31), pages 307 - 317 *

Also Published As

Publication number Publication date
WO2013105105A2 (fr) 2013-07-18

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