WO2013103475A3 - Scanner spectroscopique portatif basé sur une sonde à fibre optique destiné à un diagnostic rapide du cancer - Google Patents
Scanner spectroscopique portatif basé sur une sonde à fibre optique destiné à un diagnostic rapide du cancer Download PDFInfo
- Publication number
- WO2013103475A3 WO2013103475A3 PCT/US2012/068795 US2012068795W WO2013103475A3 WO 2013103475 A3 WO2013103475 A3 WO 2013103475A3 US 2012068795 W US2012068795 W US 2012068795W WO 2013103475 A3 WO2013103475 A3 WO 2013103475A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optical fiber
- cancer diagnosis
- fiber probe
- portable optical
- based spectroscopic
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 239000000523 sample Substances 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000013307 optical fiber Substances 0.000 title 1
- 238000001069 Raman spectroscopy Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000001506 fluorescence spectroscopy Methods 0.000 abstract 1
- 238000001055 reflectance spectroscopy Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0272—Handheld
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
Abstract
L'invention concerne un système de sonde multimodale, destiné au balayage spectroscopique d'un tissu pour le diagnostic d'une maladie. Le système peut utiliser une spectroscopie à réflectance diffuse, une spectroscopie à fluorescence et une spectroscopie Raman pour la détection d'un tissu cancéreux, telle qu'une évaluation de rebord de tissu.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161569095P | 2011-12-09 | 2011-12-09 | |
US61/569,095 | 2011-12-09 | ||
US13/338,920 | 2011-12-28 | ||
US13/338,920 US20120302892A1 (en) | 2005-07-25 | 2011-12-28 | Portable optical fiber probe-based spectroscopic scanner for rapid cancer diagnosis |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013103475A2 WO2013103475A2 (fr) | 2013-07-11 |
WO2013103475A3 true WO2013103475A3 (fr) | 2015-06-18 |
Family
ID=48745530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2012/068795 WO2013103475A2 (fr) | 2011-12-09 | 2012-12-10 | Scanner spectroscopique portatif basé sur une sonde à fibre optique destiné à un diagnostic rapide du cancer |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2013103475A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012142301A2 (fr) | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Procédé de détermination d'un protocole de traitement et/ou d'un pronostic de rétablissement d'un patient à la suite d'un traumatisme cérébral |
GB201302886D0 (en) * | 2013-02-19 | 2013-04-03 | Univ Singapore | Diagnostic instrument and method |
US11129577B2 (en) | 2015-02-17 | 2021-09-28 | Telebyte, Inc. | Optical cancer detector using deep optical scanning and multi layer neural network |
US20160235372A1 (en) * | 2015-02-17 | 2016-08-18 | Telebyte, Inc. | Portable cancer diagnostic device and system |
JP2018515753A (ja) * | 2015-04-06 | 2018-06-14 | マサチューセッツ インスティテュート オブ テクノロジー | ハイパースペクトル・イメージングのためのシステムおよび方法 |
EP3359954A1 (fr) | 2015-10-07 | 2018-08-15 | CellTool GmbH | Dispositif et procédé pour déceler et/ou évaluer des états pathologiques |
DE102017010397A1 (de) * | 2017-11-09 | 2019-05-09 | FotoFinder Systems GmbH | Verfahren zur Auswertung des Hautbildes eines Menschen im Rahmen der Hautkrebs-Vorsorgeuntersuchung sowie Vorrichtung zu dessen Betrieb |
WO2019142136A1 (fr) * | 2018-01-17 | 2019-07-25 | Ods Medical Inc. | Système et procédés de spectroscopie raman en temps réel pour une détection de cancer |
WO2019199865A1 (fr) * | 2018-04-10 | 2019-10-17 | Quanterix Corporation | Quantification de biomarqueurs présents dans des échantillons physiologiques séchés |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5353790A (en) * | 1992-01-17 | 1994-10-11 | Board Of Regents, The University Of Texas System | Method and apparatus for optical measurement of bilirubin in tissue |
US5916171A (en) * | 1994-05-31 | 1999-06-29 | Mayevsky; Avraham | Tissue monitor |
US6069689A (en) * | 1997-04-16 | 2000-05-30 | Derma Technologies, Inc. | Apparatus and methods relating to optical systems for diagnosis of skin diseases |
US20040089816A1 (en) * | 2002-08-09 | 2004-05-13 | California Institute Of Technology | Method and system for scanning apertureless fluorescence microscope |
US20070057211A1 (en) * | 2005-05-25 | 2007-03-15 | Karsten Bahlman | Multifocal imaging systems and method |
US20070167835A1 (en) * | 2005-07-25 | 2007-07-19 | Massachusetts Institute Of Technology | Tri modal spectroscopic imaging |
US20090015826A1 (en) * | 2006-03-30 | 2009-01-15 | Duke University | Optical assay system for intraoperative assessment of tumor margins |
US20100034743A1 (en) * | 2008-08-08 | 2010-02-11 | Chemlmage Corporation | Raman Characterization of Transplant Tissue |
-
2012
- 2012-12-10 WO PCT/US2012/068795 patent/WO2013103475A2/fr active Application Filing
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5353790A (en) * | 1992-01-17 | 1994-10-11 | Board Of Regents, The University Of Texas System | Method and apparatus for optical measurement of bilirubin in tissue |
US5916171A (en) * | 1994-05-31 | 1999-06-29 | Mayevsky; Avraham | Tissue monitor |
US6069689A (en) * | 1997-04-16 | 2000-05-30 | Derma Technologies, Inc. | Apparatus and methods relating to optical systems for diagnosis of skin diseases |
US20040089816A1 (en) * | 2002-08-09 | 2004-05-13 | California Institute Of Technology | Method and system for scanning apertureless fluorescence microscope |
US20070057211A1 (en) * | 2005-05-25 | 2007-03-15 | Karsten Bahlman | Multifocal imaging systems and method |
US20070167835A1 (en) * | 2005-07-25 | 2007-07-19 | Massachusetts Institute Of Technology | Tri modal spectroscopic imaging |
US20090015826A1 (en) * | 2006-03-30 | 2009-01-15 | Duke University | Optical assay system for intraoperative assessment of tumor margins |
US20100034743A1 (en) * | 2008-08-08 | 2010-02-11 | Chemlmage Corporation | Raman Characterization of Transplant Tissue |
Also Published As
Publication number | Publication date |
---|---|
WO2013103475A2 (fr) | 2013-07-11 |
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