WO2013100822A3 - Гемостимулирующее средство - Google Patents
Гемостимулирующее средство Download PDFInfo
- Publication number
- WO2013100822A3 WO2013100822A3 PCT/RU2012/001120 RU2012001120W WO2013100822A3 WO 2013100822 A3 WO2013100822 A3 WO 2013100822A3 RU 2012001120 W RU2012001120 W RU 2012001120W WO 2013100822 A3 WO2013100822 A3 WO 2013100822A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hemostimulating
- agent
- cysteinyl
- glutamyl
- glycine
- Prior art date
Links
- 230000000633 hematostimulatory effect Effects 0.000 title 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 230000011132 hemopoiesis Effects 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Согласно данному изобретению предложены комбинация бис-(γ-L-глутамил)-L-цистеинил-глицина дилитиевой соли и координационных соединений, образованных палладием, медью и (γ-L-глутамил)-L-цистеинил-глицином, содержащая такую комбинацию фармацевтическая композиция, а также способ стимулирования гемопоэза с их использованием.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2011154536/15A RU2482869C1 (ru) | 2011-12-30 | 2011-12-30 | Гемостимулирующее средство, фармацевтическая композиция и способ стимулирования гемопоэза |
RU2011154536 | 2011-12-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013100822A2 WO2013100822A2 (ru) | 2013-07-04 |
WO2013100822A3 true WO2013100822A3 (ru) | 2013-09-26 |
Family
ID=48698768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2012/001120 WO2013100822A2 (ru) | 2011-12-30 | 2012-12-27 | Гемостимулирующее средство |
Country Status (2)
Country | Link |
---|---|
RU (1) | RU2482869C1 (ru) |
WO (1) | WO2013100822A2 (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019099753A1 (en) * | 2017-11-15 | 2019-05-23 | The Translational Genomics Research Institute | Biomarker proxy tests and methods for standard blood chemistry tests |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992021368A1 (en) * | 1991-06-06 | 1992-12-10 | Life Sciences' Technologies, Inc. | Composition and method for disease treatment |
RU2153350C1 (ru) * | 1998-11-23 | 2000-07-27 | Закрытое акционерное общество "ВАМ" | Композит гексапептида со стабилизированной дисульфидной связью с веществом металлом, фармацевтические композиции на его основе, способы их получения и применения для лечения заболеваний на основе регуляции метаболизма, пролиферации, дифференцировки и механизмов апоптоза в нормальных и патологически измененных тканях |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2178710C1 (ru) * | 2001-02-08 | 2002-01-27 | Кожемякин Леонид Андреевич | Индивидуальные вещества, полученные на основе химического взаимодействия дисульфидсодержащих пептидов с производными пуриновых или пиримидиновых оснований, фармацевтические композиции и препараты на их основе, способы их применения для лечения инфекционных заболеваний и профилактики осложнений |
-
2011
- 2011-12-30 RU RU2011154536/15A patent/RU2482869C1/ru active
-
2012
- 2012-12-27 WO PCT/RU2012/001120 patent/WO2013100822A2/ru active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992021368A1 (en) * | 1991-06-06 | 1992-12-10 | Life Sciences' Technologies, Inc. | Composition and method for disease treatment |
RU2153350C1 (ru) * | 1998-11-23 | 2000-07-27 | Закрытое акционерное общество "ВАМ" | Композит гексапептида со стабилизированной дисульфидной связью с веществом металлом, фармацевтические композиции на его основе, способы их получения и применения для лечения заболеваний на основе регуляции метаболизма, пролиферации, дифференцировки и механизмов апоптоза в нормальных и патологически измененных тканях |
US7169412B2 (en) * | 1998-11-23 | 2007-01-30 | Novelos Therapeutics, Inc. | Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells |
Non-Patent Citations (1)
Title |
---|
KORIK E.O. ET AL.: "Okislitelnoe povrezhdenie glutation S-transferaz pechenikrys pri vzaimodeistvii s mediu i bilirubinom.", VESTNIK BGU. SER. 2, 2008, pages 42 - 47 * |
Also Published As
Publication number | Publication date |
---|---|
WO2013100822A2 (ru) | 2013-07-04 |
RU2482869C1 (ru) | 2013-05-27 |
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