WO2013088370A3 - Use of the protein mmp-12 in the prevention and/or treatment of sensitive skin - Google Patents

Use of the protein mmp-12 in the prevention and/or treatment of sensitive skin Download PDF

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Publication number
WO2013088370A3
WO2013088370A3 PCT/IB2012/057239 IB2012057239W WO2013088370A3 WO 2013088370 A3 WO2013088370 A3 WO 2013088370A3 IB 2012057239 W IB2012057239 W IB 2012057239W WO 2013088370 A3 WO2013088370 A3 WO 2013088370A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensitive skin
polypeptide
seq
prevention
treatment
Prior art date
Application number
PCT/IB2012/057239
Other languages
French (fr)
Other versions
WO2013088370A2 (en
Inventor
Isabelle Castiel
Audrey Gueniche
Original Assignee
L'oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L'oreal filed Critical L'oreal
Publication of WO2013088370A2 publication Critical patent/WO2013088370A2/en
Publication of WO2013088370A3 publication Critical patent/WO2013088370A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin

Abstract

The present invention relates to the cosmetic use of an effective amount of at least one active agent consisting of a polypeptide having at least 80% amino acid identity with a metalloprotease MMP-12 whose sequence is chosen from SEQ ID NO: 1, SEQ ID NO: 2 and SEQ ID NO: 3 indicated below, or a C-terminal fragment of this polypeptide, for preventing and/or treating sensitive skin, the said polypeptide or the said fragment comprising the sequence KDXK, in which X represents aspartic acid or glutamic acid. The present invention is directed mainly toward proposing a novel active agent for preventing and/or treating sensitive skin.
PCT/IB2012/057239 2011-12-14 2012-12-12 Use of the protein mmp-12 in the prevention and/or treatment of sensitive skin WO2013088370A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR1161620 2011-12-14
FR1161620A FR2984128A1 (en) 2011-12-14 2011-12-14 USE OF PROTEIN MMP-12 IN THE PREVENTION AND / OR TREATMENT OF SENSITIVE SKINS.
US201261608953P 2012-03-09 2012-03-09
US61/608,953 2012-03-09

Publications (2)

Publication Number Publication Date
WO2013088370A2 WO2013088370A2 (en) 2013-06-20
WO2013088370A3 true WO2013088370A3 (en) 2013-12-27

Family

ID=46229532

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/057239 WO2013088370A2 (en) 2011-12-14 2012-12-12 Use of the protein mmp-12 in the prevention and/or treatment of sensitive skin

Country Status (2)

Country Link
FR (1) FR2984128A1 (en)
WO (1) WO2013088370A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003087325A2 (en) * 2002-04-08 2003-10-23 The Brigham And Women's Hospital, Inc. Methods and compositions for preventing and treating microbial infections
WO2009111083A2 (en) * 2008-03-06 2009-09-11 Halozyme, Inc. In vivo temporal control of activ at able matrix- degrading enzymes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0852949A3 (en) 1997-03-31 1999-08-04 Shiseido Company Limited Use of alpha-amino-acids for enhancing desmosomal degradation or stratum corneum desquamation
EP1374913A1 (en) 2002-06-25 2004-01-02 L'oreal Nontherapeutic process for evaluating cutaneous neurosensitivity, corresponding kit and its use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003087325A2 (en) * 2002-04-08 2003-10-23 The Brigham And Women's Hospital, Inc. Methods and compositions for preventing and treating microbial infections
WO2009111083A2 (en) * 2008-03-06 2009-09-11 Halozyme, Inc. In vivo temporal control of activ at able matrix- degrading enzymes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ESCALAS-TABERNER J ET AL: "Sensitive Skin: A Complex Syndrome", ACTAS DERMOSIFILIOGRAFICAS (ENGLISH EDITION), ELSEVIER, AMSTERDAM, NL, vol. 102, no. 8, 27 April 2011 (2011-04-27), pages 563 - 571, XP028393326, ISSN: 1578-2190, [retrieved on 20111021], DOI: 10.1016/J.ADENGL.2011.04.002 *

Also Published As

Publication number Publication date
FR2984128A1 (en) 2013-06-21
WO2013088370A2 (en) 2013-06-20

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