WO2013085889A8 - Identification and cloning of transmitted hepatitic c virus (hcv) genomes by single genome amplification - Google Patents

Identification and cloning of transmitted hepatitic c virus (hcv) genomes by single genome amplification Download PDF

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Publication number
WO2013085889A8
WO2013085889A8 PCT/US2012/067731 US2012067731W WO2013085889A8 WO 2013085889 A8 WO2013085889 A8 WO 2013085889A8 US 2012067731 W US2012067731 W US 2012067731W WO 2013085889 A8 WO2013085889 A8 WO 2013085889A8
Authority
WO
WIPO (PCT)
Prior art keywords
hcv
genomes
transmitted
virus
hepatitic
Prior art date
Application number
PCT/US2012/067731
Other languages
French (fr)
Other versions
WO2013085889A1 (en
Inventor
George M. Shaw
Hui Li
Beatrice H. Hahn
Barton F. Haynes
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Priority to EP12854779.1A priority Critical patent/EP2788490A1/en
Publication of WO2013085889A1 publication Critical patent/WO2013085889A1/en
Publication of WO2013085889A8 publication Critical patent/WO2013085889A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24221—Viruses as such, e.g. new isolates, mutants or their genomic sequences

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides transmitted full-length hepatitis C virus (HCV) genomes that mediate viral transmission and clinical infection, and methods for identifying nucleotide sequences corresponding to specific transmitted HCV genomes.
PCT/US2012/067731 2011-12-05 2012-12-04 Identification and cloning of transmitted hepatitic c virus (hcv) genomes by single genome amplification WO2013085889A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12854779.1A EP2788490A1 (en) 2011-12-05 2012-12-04 Identification and cloning of transmitted hepatitic c virus (hcv) genomes by single genome amplification

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161630161P 2011-12-05 2011-12-05
US61/630,161 2011-12-05

Publications (2)

Publication Number Publication Date
WO2013085889A1 WO2013085889A1 (en) 2013-06-13
WO2013085889A8 true WO2013085889A8 (en) 2013-11-28

Family

ID=48574801

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/067731 WO2013085889A1 (en) 2011-12-05 2012-12-04 Identification and cloning of transmitted hepatitic c virus (hcv) genomes by single genome amplification

Country Status (2)

Country Link
EP (1) EP2788490A1 (en)
WO (1) WO2013085889A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60135366D1 (en) * 2000-04-18 2008-09-25 Virco Bvba METHOD FOR DETERMINING RESISTANCE TO MEDICAMENTS
KR101154278B1 (en) * 2004-02-20 2012-06-21 도레이 카부시키가이샤 Nucleic acid construct containing full-length genome of human hepatitis c virus, recombinant full-length virus genome replicative cell having the nucleic acid construct transferred thereinto and method of constructing hepatitis c viral particles
WO2012033904A1 (en) * 2010-09-08 2012-03-15 Duke University Identification of transmitted hepatitis c virus (hcv) genomes by single genome amplification

Also Published As

Publication number Publication date
EP2788490A1 (en) 2014-10-15
WO2013085889A1 (en) 2013-06-13

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