WO2013082978A1 - Graphe de procédure d'immunisation et procédé de construction de ce graphe et procédé et système de traitement d'informations d'inoculation - Google Patents

Graphe de procédure d'immunisation et procédé de construction de ce graphe et procédé et système de traitement d'informations d'inoculation Download PDF

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Publication number
WO2013082978A1
WO2013082978A1 PCT/CN2012/083567 CN2012083567W WO2013082978A1 WO 2013082978 A1 WO2013082978 A1 WO 2013082978A1 CN 2012083567 W CN2012083567 W CN 2012083567W WO 2013082978 A1 WO2013082978 A1 WO 2013082978A1
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WIPO (PCT)
Prior art keywords
vaccination
node
vaccine
program
immune
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PCT/CN2012/083567
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English (en)
Chinese (zh)
Inventor
吴卫民
Original Assignee
Wu Weimin
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Publication of WO2013082978A1 publication Critical patent/WO2013082978A1/fr

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection

Definitions

  • the invention belongs to the field of computer software, and in particular relates to an immune program diagram and a method for establishing the same, and a method and system for processing the seeding information. Background technique
  • a vaccine is a biological product that stimulates the body's immunity to disease, thereby preventing or reducing the effects of disease pathogen infection.
  • the description of the vaccine product gives a method for the use of a vaccine based on clinical analysis studies, usually through multiple doses of vaccination to achieve the best preventive effect.
  • immunization There are still some situations in the implementation of immunization that are not covered in the instructions for the vaccine product, but they must be handled correctly. For example, simultaneous and isochronous vaccination of different vaccines; selection of vaccination time for multiple or multiple attenuated inactivated vaccinations.
  • the National Center for Disease Control and Prevention is responsible for formulating rules related to immunization. In addition to the regulations on the use of vaccine products, the rules also provide some treatments for the actual implementation of immunization.
  • the immunization program is an immunization implementation method based on this rule.
  • a computer program is needed to interpret the immunization program and automatically analyze and process data related to immunization, such as assessing a person's immunization history and recommending the immunizations required for this person in the future.
  • This computer program should also include some of the decision-making functions of the immunization practitioner, such as those directly related to the immunization program; updating and using the latest version of the immunization program; and selecting the appropriate version of the immunization program when processing historical data.
  • another object of the present invention is to provide a method and system that can be used for immunological program visualization establishment and maintenance methods and systems, as well as for processing vaccination information Immune program map.
  • the technical solution of the invention is as follows - an immunological program diagram comprising a plurality of nodes and a plurality of vector lines,
  • one of said nodes represents a dose of vaccination of the immunization program and its attributes, said attributes including conditional information for vaccination of the dose;
  • the following data structure is used to store information about a node of the immune program map and its subsequent nodes and can be processed with dry vaccination information:
  • the data structure includes the following data elements: (1) an identifier (201) that uniquely identifies the node, (2) a dose of agent information (202) corresponding to the node, and (3) The next inoculation of the inoculation is followed by information on the subsequent node information (203).
  • the agent information includes a set of constraints.
  • the vaccine constraint in the constraint is information on the meta-vaccine.
  • the constraint includes a constraint of a valid date range (221) of a node.
  • the subsequent node information (203) includes priority information for each subsequent node.
  • a method of generating and maintaining an immune program for use in vaccination information processing organized by an immunological program providing a graphical user interface on a computer to enable a user to establish and maintain the aforementioned immune program map, including;
  • the user interface includes a dynamic menu and toolbar generation and management module based on an immune program related object for generating and managing a task menu and a toolbar based on the selected immune program related object. To guide, build, maintain, and manage immune program maps.
  • the user interface also includes an immune program assisted design task module for automatically generating and completing, self-consistent inspection and maintenance of interrelated data in the immune program map.
  • the immune program assisted design task module includes the task of generating a meta-vaccine by a vaccine.
  • the immune program assisted design task module includes the task of generating a vaccine or meta-vaccine immune program map framework from a vaccine or meta-vaccine.
  • the immune program assisted design task module includes a task of analyzing constraint overlap between subsequent nodes of a node
  • the criterion for judging that the two node constraints do not overlap is: comparing the range of parameter values of the same constraint of the two nodes. If there are two nodes with the same constraint, the parameter values are completely repulsive, then the two knots The points do not overlap.
  • the method of generating and maintaining an immune program organized by the immune program map for processing the vaccination information further includes issuing an immune program map on the computer for establishing and maintaining.
  • the immune program map established and maintained by the distribution refers to the release of the immune program map in a graphic format, including:
  • a legend is used to illustrate the meaning of symbols, characters, strings, and graphic elements in the immune block diagram.
  • a method of processing vaccination information wherein the immunization program is based on the aforementioned immunological program map, and the information about the vaccine of the immunization schedule is meta-vaccine information, the method comprising the steps of:
  • Each injection in the vaccination history of the vaccinator is converted into a vaccination injection and stored in the vaccination history (1124);
  • the processing method for the system in the step of evaluating the recommendation process is - a) initializing the subsequent node set (1125), assigning the set of all the initial nodes of the system to the subsequent node set;
  • the recommendation of a series of future vaccination refers to determining the future vaccination of a line within the recommended date range [T staii , U, and recommending that the future vaccination of the line does not require the end of the system's immune program map or although the system is used
  • the recommending a future vaccination refers to determining a future vaccination on a recommended date, I [T startJ T e; id ] ⁇ It is recommended that the future inoculation of the line be 3 ⁇ 4 to the end of the line's immunization map, which includes the optional inoculation constraint, the step is - first check if the optional inoculation constraint is met; , then continue the recommendation process according to the endpoint without the optional vaccination constraint; otherwise, the vaccination of the system has been completed, and one method of processing the system in the system-by-system evaluation process is : If the line has a cut-off age, the agent checks whether the age of the vaccinator has exceeded the cut-off age before the evaluation process, and exits the treatment of the line if it exceeds; otherwise, the evaluation and recommended treatment of the line are continued.
  • One method for the one-line evaluation of the treatment in the recommendation process is: if the system has a deadline for the system, and after the evaluation is completed, the vaccination procedure is not completed, then the test is performed before the recommendation process Whether the age of the vaccinator has exceeded the cut-off age, and if it exceeds, the treatment of the system is withdrawn; otherwise, the recommended treatment of the system is continued.
  • a system comprising: means for performing the steps of the foregoing method.
  • the foregoing methods are: ⁇ ) - a method of generating and maintaining an immune program organized by an immunological program for use in vaccination information processing, and (2) a method of processing vaccination information.
  • the present invention provides a method and system for establishing and maintaining an ISG.
  • the user can graphically and intuitively design, edit, and view the relationship between the nodes corresponding to the ISG doses on the computer, and input and edit. Manage ISG data.
  • the introduction of the system also simplifies the dependence of each dose of the combination vaccine, facilitating the design, maintenance and operation of the ISG.
  • the present invention provides a method and system for processing vaccination information using BG. The high availability performance of this system is improved because the method described above reduces the time required for the immune program to change the response to the system in which the vaccination information is processed.
  • the introduction of the system also makes it easier to design and maintain software that processes the vaccinator information method, thereby making the system for processing vaccinator information easier to maintain.
  • the user can process the vaccinator information by ffl, a system that causes the ffl ISG to represent the immunization program.
  • the present invention organically integrates various vaccination-related data involved in the immunization program to provide an easy-to-use data platform and system for medical institutions or individual users.
  • the data platform and system can be used for users.
  • Figure 2 is a block diagram showing a method for visualizing an immune program according to an embodiment of the present invention
  • Figure 2 is a block diagram showing a data hook of an ISG according to an embodiment of the present invention
  • Figure 3 is a block diagram showing an embodiment of an ISG according to an embodiment of the present invention Schematic diagram of ISCAD;
  • FIG. 4 is a schematic diagram showing a user interface of a CAD when a vaccine is selected according to an embodiment of the present invention
  • FIG. 5 is a schematic diagram showing a user interface when a CAD vaccine is selected according to an embodiment of the present invention
  • FIG. 6 is a schematic diagram showing a user interface when an ISCAD immune program generation module is selected according to an embodiment of the present invention
  • FIG. 7 is a schematic diagram showing a GUI of a CAD when a system of immune programs is selected according to an embodiment of the present invention
  • FIG. 8 is a schematic diagram showing an ISG distributed in a graphic format according to an embodiment of the present invention
  • FIG. 9 is a schematic diagram showing a data structure of a vaccination information processing state according to an embodiment of the present invention
  • FIG. 10 a) is a diagram showing an implementation according to the present invention
  • Figure 10 b is a block diagram showing a processing method in accordance with an embodiment of the present invention.
  • the invention will be further described in detail below with reference to the drawings and specific embodiments.
  • the embodiments of the invention are illustrative of the invention and are not intended to limit the invention.
  • Graph The concept in the graph theory and the corresponding computer algorithm.
  • a diagram is used to abstractly represent a set of objects (o ect) called vertices or nodes, some of which have links, called edges or lines (lme).
  • a sequence of nodes that are wired together between nodes is called a path.
  • a set of nodes in a graph if its edges exist only within the set of nodes, then the set of nodes and their edges form a subgraph of the graph. If all the lines in a graph are directional, the graph is a directed graph whose edges are also called arcs or arrows. The node at the end of the arrow of all the vector lines starting at a node is the subsequent node of the node.
  • Immunization schedule refers to immunization implementation rules and methods.
  • the immunization program includes the vaccination target to be vaccinated, the vaccine to be vaccinated, the number of doses, the age range of the vaccinated subjects at each dose, the interval between vaccinations, and the route of vaccination.
  • the information in the immunization program to determine which vaccine to vaccinate and which vaccine to receive, and how to inoculate the vaccine is also referred to as conditional information in this description.
  • the vaccination object completes the immunization against the disease by completing the dose number for one disease according to the immunization program.
  • Immunization program Information on the condition of a single dose of vaccination including the age at which the vaccinator is vaccinated, the optional vaccine, and the time interval between other accepted vaccinations, etc., can be expressed in a set of conditions, whether the vaccinator should be vaccinated The dose of this dose depends on whether these conditions can be met.
  • Immrniization schedule graph Refers to the immune program represented by a graph, including immune program data organized by graph structure, and corresponding computer algorithms.
  • Vaccination information processing Analytical processing and processing results based on immunization procedures, information on vaccinators.
  • the vaccinator is the recipient of the vaccine, corresponding to one of the vaccinated individuals in the immunization program.
  • the vaccinator information is information related to the vaccination of the vaccinator including information of the individual of the vaccinator, such as the age, sex of the vaccinator, and vaccination information of the vaccinator, such as the vaccination history of the vaccinator.
  • the vaccination history of the vaccinator is all vaccination received by the vaccinator, and one injection includes the vaccine vaccinated by the vaccinator and the date of vaccination.
  • the information on the one-time vaccination of the immunization program contains conditions under which the vaccinator's one injection corresponds to the vaccination, depending on the vaccinator information and whether the injection satisfies the conditions of the vaccination. If one injection corresponds to one dose of the dry immunization program, the injection is effectively vaccinated, otherwise it is ineffective.
  • Department Refers to a concept used in this description.
  • Some of the information related to the immunization program can be grouped according to the type of disease that the immunization is guarded against, called a line: the system can have the same name as its corresponding disease, such as the HepA line.
  • the immunization schedule may be independent of each other, ie, the vaccination of the vaccinated person after the injection or vaccination with the attenuated inactivated vaccine is processed. History - can be handled separately by department.
  • a line can also be obtained by combining several lines. For example, when the MMR system makes the combined vaccine MMR, the line can be treated separately as described above.
  • this age ⁇ ⁇ is defined as the cut-off age of the department.
  • Atom Vaccine A concept used in this description.
  • a meta-vaccine is a component of a vaccine product that targets a disease, such as an immunogen or immune effector for a disease.
  • a combination vaccine can be broken down into a plurality of meta-vaccinations, that is, one dose of vaccination containing the combined vaccine can be divided into vaccination of several doses of the primordial vaccine, each dose of the vaccination Vaccination with a one-way vaccine; a single injection containing a combination vaccine can be divided into several injections of a vaccine containing a dollar vaccine (cominiter): a computer in the natural sense, such as a personal computer (PC), or mobile
  • a smart phone, personal data assistant (PDA) or supercomputer usually connected by multiple functional units connected by some form of communication bus Bus, such as a processor (CPU), memory (RAM, ROM), input and output
  • CPU processor
  • RAM random access memory
  • ROM read-only memory
  • the device external storage of various storage media, wired or wireless network communication devices, and the like.
  • OS operating systems
  • application software programs running on them.
  • the application's encoding instructions are stored on a computer readable medium, and when the program is run, the program's instructions are loaded into the computer's memory and executed to provide the functionality of the method implemented by the application.
  • An application that implements a method can be either an executable program or an integrated or separate software module.
  • API application programming interface
  • Collection Data structures and algorithms involving collection sequences in the computer domain, as in the list (Ust).
  • each element in the collection is sequentially read in a loop, according to the storage location of the element, assigned to a variable, and then the content of the variable is processed; In the process, it is usually used to determine whether there is still an operation of the next element, that is, whether the end of the set sequence has been reached. The operation determines whether the traversal loop should end; if there is a next element, the next element is read for corresponding processing: if not, the loop is exited, that is, all elements of the set have been processed.
  • FIG. 1 is a block diagram showing a method for visualizing an immune program according to an embodiment of the present invention.
  • One dose of vaccination of the immunization program and its attributes, including conditional information that should be met when the dose is inoculated is represented by a node 101, 103, 105 106 in the directed graph 100; a node 101 inoculated with one dose Connected to the node 103 indicating the next dose of the inoculation with a vector line 02, the vector arrow points to the node 103 of the next dose, ie, node 101 represents the previous dose of the two doses. Sub-vaccination, node 103 indicates the next dose of vaccination.
  • Subsequent nodes 103, 105 of node 101 are the corresponding nodes for all possible next doses of a single dose of vaccination represented by node 101.
  • the vector line 104 is finally dry and the same node is used to indicate the periodic booster dose:.
  • a siart node 101 represents a first dose of vaccination of the immunization program represented by Figure 100, and an end node: 06 indicates a last dose of the immunization program.
  • An immune program map can have multiple start nodes or endpoints. The path from a start node to an endpoint indicates a possible way to complete the immunization against a disease in the immunization program represented by the immune program map. .
  • the route i0i-103-106 indicates that three doses of vaccination are required to complete the immunization required by the immunization program shown in Figure 100, the immunological program map 100.
  • An immune program map can have multiple pathways indicating possible ways to complete immunization.
  • immunological program map is to select one or several pathways in the ISG to vaccinate the vaccinated subject against various diseases as specified or recommended by the immunization program.
  • a series of ISGs may be composed of one or more immune program subgraphs associated with the vaccine of the system; in a series of ISGs, an inoculation object only needs to complete a path from a starting node to an ending point. The immunization of the line was completed.
  • the complete ISG can be of the ffl system: SG is composed of subgraphs.
  • a method of selecting a path for a line of ISGs includes determining a path representative of the history of vaccination based on a vaccination history of a vaccinator corresponding to the line, a process referred to as assessment (E va !uaiiOii). Evaluation method is For each injection in the vaccination history, in the G of the line, according to the vaccination condition information of each node,
  • a node If a node is found for an injection, this injection is effectively vaccinated. At the end of the assessment, if the immunization of the line has not been completed, the last node in the path representing the history of the inoculation can be used to determine the future inoculation required by the inoculator, any subsequent knot of the node. The point represents the next vaccination that the vaccinator can take, and the subsequent node of the node can be used to determine the future vaccination of the line that the vaccinator needs and can take. This process is called recommendation ( Recommendation).
  • Data structure 200 is a block diagram of a data structure 200 of an iSG in accordance with an embodiment of the present invention.
  • Data structure 200 is a block diagram of a data structure 200 of an iSG in accordance with an embodiment of the present invention.
  • this data structure can be used to establish an immune program map and for vaccination information processing.
  • the data structure includes the following data elements: an identifier 201 that uniquely identifies the node; a dose information information 202 corresponding to the dose of the dose corresponding to the node, including condition information 233 inoculated with the agent; The next dose of vaccination information is followed by node information 203.
  • Condition information 233 can be a set of constraints 204.
  • This dose of vaccine is vaccinated; it can be a meta-vaccine code 209, or it can be a common plague code 213.
  • Licensing allows ffi date range
  • the license's license usage date is determined by the start and end dates.
  • Minimum annual range The minimum annual range of vaccinated subjects allowed for this dose of vaccination is determined by the start and end periods, usually only the start date. Usually used only for evaluation.
  • Minimum time interval The minimum time interval between the dose of the dose and the time of the previous dose. Usually used only for evaluation.
  • Minimum time interval ⁇ The minimum interval between the dose of the dose and the time of the previous dose.
  • Recommended Age Range The recommended age range for the vaccination for this dose is determined by the start and end dates, usually using only the start date. Usually only recommended.
  • Optional vaccination 218 The vaccinated subject should receive the vaccination for the time of the previous dose if it is within a certain age.
  • the same vaccine requires vaccine 207 to be the same vaccine as the vaccine used in the previous dose.
  • This node is only used for an injection that corresponds to the evaluation of this node.
  • Tdap Tetanus-Diphtheria-Pertussis
  • Tdap Tetanus, Diphtheria anc Pertussis ⁇ Date of birth range
  • Measles, mumps and rubella MMR::: Measles, mumps and rabei! a
  • Effective Date Range 221 The effective date range for this node, determined by the start and end dates. The mark used to change the history of the immunization program, ie the conditions for a single dose of vaccination have a suitable date.
  • Age range 219 The age range of the vaccinated subjects allowed for this dose is determined by the start and end periods.
  • the vaccine 207 constraint may be the code 213 of the vaccine 210 or the element derived from the vaccine 210.
  • Vaccine 2i0 is used to store information about a vaccine; meta-vaccine 208 is used for storage
  • vaccine 210 may contain the above identification code 2] 3, and the permitted use time range 214,
  • Component list 216 is vaccine 210
  • Each component of the component list 2]6 may be the name of the component 217 and the associated system 2]2.
  • the license time range 214 is the date range for the licensed use of the vaccine 2]0. Attenuated inactivated vaccine 215
  • the meta vaccine 208 can include the identification code described above
  • vaccine code 211 is 212.
  • vaccine code 211 and line 212 are corresponding to the original vaccine.
  • the code 210 of the vaccine 210 and the component of the component 212 are identical to each other.
  • condition information 233 is described using a set of constraints 204, which is to be made in a series of ISGs.
  • the constraint 204 of any two subsequent nodes of a node does not overlap, Lang: the same constraint of the two nodes At least one of the parameters in the condition is completely exclusive. For example, the example of the value of the constraint is completely repelled:
  • the two-node vaccine constraint 207 is different: the time-related constraints of the two nodes, such as the age range 219, do not intersect. In the case where the two node constraints 204 overlap, a dose of vaccination may satisfy the constraints of the two nodes, which makes the evaluation of the vaccination history in the vaccination information processing complicated, and therefore should be avoided. This is the case.
  • the subsequent node information 203 is a list 206 of subsequent node pairs, wherein the identifier 231 of the pair 205 is an identifier of a subsequent node, and the priority 232 is all subsequent nodes of the subsequent node in the list 206.
  • the priority in the point is used to assist in determining the priority of each subsequent node selected in the vaccination information processing.
  • FIG. 3 is a block diagram diagram of the computer aided design system (ISCAD) 300 of the present invention.
  • the ISCAD 300 includes an immune program assisted design input interface 301, and an immune program storage 307. These components 301, 307 can be implemented in the form of integrated or distributed functional modules, and the SCAD 300 applications composed of these functional modules are usually stored on a computer readable medium together with an operating system and other applications.
  • the program instructions are loaded into the computer's memory and executed, so that the computer can help and guide the user to input and maintain vaccine data, graphically design, establish and maintain the immune program. Test the immunization program and related documentation.
  • the immune program assisted design input interface 30 includes an immune program object management module 302, a vaccine editing module 303, a meta vaccine editing module 304, an immune program map editing module 305, and an immune program assist design task 306.
  • the immunization program input interface 301 is also integrated with an immunization program publishing engine 308 for issuing ISGs.
  • the immune program assisted design input interface 301 can be used in conjunction with the auxiliary design task 306 for automatic generation and integrity of dependent data, maintenance, maintenance, cleanup, and the like.
  • the user can enable the immune program management module 302 and its graphical user interface to classify and manage, add, delete, copy, paste, search, select, edit, and edit objects related to the immune program, and read from the immune program storage 307 or store the immune program 307.
  • 4 is a schematic diagram of a user interface 400 when an iSCAD 300 is selected as a vaccine in accordance with an embodiment of the present invention.
  • the user interface 400 displays the browser user interface 401 of the object management module 302 and the vaccine creation user interface 402 of the vaccine editing module 303 and the output information browser 407 of the user interface 301.
  • the browser user interface 401 is used to organize and manage immune program related objects.
  • Immune program related objects can be displayed in a tree structure In the browser user interface 40, the user can search and manage the immune program related data and information according to the type of the object related to the immunization program.
  • the first level node of the tree structure may be the system 403 or the combination vaccine 404; under the system node 403 may be the classified nodes 4i0-412 belonging to the object of the system; under the combined vaccine node 404 Is a node 413-4M belonging to the classification of the object of the combined vaccine; under a classification node 410-414 may be an individual object or entity belonging to the class, the node itself may also correspond to the comprehensive object or entity of the classification, for example Immune program node 412 may correspond to a series of ISGs, and under this node 412 is an ISG 405 for the individual vaccines of the system.
  • the user can add, delete, copy, paste, search, select, edit a family 403, a combined vaccine 404, a class of object classification nodes 4i0-414,
  • an editing module corresponds to the object
  • the user can cause the editing module corresponding to ffl to edit the data of the object. Feeding, when a vaccine 406 is selected, the vaccine's data is displayed in the user interface 402 of the vaccine editing module. The user can enter or edit various attribute values of the vaccine using the user interface 402.
  • an object 405-406, 410-414 is selected, if there is a processing task corresponding to the object in the auxiliary design task module 306, the user can use the corresponding processing task to process the selected object.
  • the immune program related object data generated during the processing will be managed by the object management module 302 and will be displayed in the interface 401.
  • the user may elect to use the sputum vaccine to generate a meta-vaccine processing task, such as using the toolbar 408 of the user interface 301 to generate a meta-vaccine from the vaccine 406.
  • the method for generating a meta-vaccine from a vaccine is: Each component of a vaccine should produce a meta-vaccine, the meta-vaccine is the line of the component, and the other parameter value of the vaccine can be the corresponding parameter value of the vaccine. .
  • the output information browsing interface 407 is used for displaying, browsing, and reading the output information of each module of the ISCAD 300.
  • FIG. 5 is a schematic illustration of user interface 500 when ISCAD 300 is selected as a meta-vaccine 502 in accordance with an embodiment of the present invention.
  • the user interface 500 displays the user interface 501 of the meta vaccine editing module 304.
  • the attribute value of the selected plague 502 is displayed in the user interface 50], and the user can use the interface 501 to input, delete, modify, and edit the attribute values of the meta vaccine.
  • the assisted design task module 306 can include a vaccine immunization program generation task module that can automatically generate a vaccine or meta-vaccine ISG based on a predefined template. Skeleton, for j3 ⁇ 4 households to edit. 6 shows a schematic diagram of the user interface when the vaccine immunization program generation task 606 of the assist design task module 306 is selected [ users can select a set of vaccines 601 using the system selection user interface 600, which may be a line or combination vaccine, the group The individual dose vaccine or vaccine 602 in vaccine 601 will be displayed in vaccine dose selection user interface 603, and the user may enter the number of doses 604 of the meta-vaccine or vaccine for immunization for each meta-vaccine or vaccine 602.
  • the user can then select, for example, use button 605 to generate a framework for the ISG of each meta-vaccine or vaccine 602 for further editing.
  • the generated iSG framework of the individual vaccine or vaccine 602 may have the same number of nodes as the number of doses 604 entered, each node will have the identifier 209 or 213 of the vaccine or vaccine 602 as a vaccine constraint and Some of the constraints and values derived from the meta-vaccine or vaccine 602 or defined in a predefined template, such as the license use date 220 constraint derived from the meta-vaccine or vaccine license time range 214, and the like.
  • FIG. 7 is a schematic diagram of the UI interface 300 of the present invention when the ISG 703 of a system is selected.
  • the user interface 700 displays the ISG creation user interface 701 of the editing module 304, and the constraint selection user interface 702.
  • the selected iSG 703 will be displayed in the user interface 701.
  • Users can use the ISG Editing Toolbar 705 to add new nodes - arbitrage between nodes, such as line 706; edit line priority; copy, crop, paste, delete selected nodes including nodes, lines and ISG graphical elements and data such as constraints.
  • the user can select the line 706 and then use the drop down list in the edit toolbar 705 to select the desired priority to assign to the line 706.
  • Different priority values can be used with different line styles. (line style) indicates.
  • the user wants to add a constraint to a node 710, such as an age range constraint, the user may choose to select the constraint in the constraint list 702 and drag and drop it to the node 710, the constraint Will be added to this node 710.
  • the household can also choose to copy a constraint 709 from one node and then paste it into another node 710.
  • the user can edit the interface 708 using constraints, such as by using the mouse to double-click the node 707 to activate the constraint editing interface 708, editing the values of the various attribute variables of the constraint.
  • constraints such as by using the mouse to double-click the node 707 to activate the constraint editing interface 708, editing the values of the various attribute variables of the constraint.
  • the auxiliary design task module 306 can include a subsequent node vaccine usage analysis task module.
  • the user can select the task on the user interface 301, for example using the toolbar 7]2.
  • the module is a node selected in the user interface 70.
  • the output information browser 407 lists information about the same type of meta-vaccine that appears in the subsequent nodes of the node and has not yet appeared, such as a meta vaccine. The identifier and its name, the user can check and consider the possibility of a non-existing meta-vaccine as a vaccine 207 for the subsequent node of the node.
  • the auxiliary design task module 306 can include a subsequent node overlap analysis task module.
  • the user can select the task module as a node selected in the user interface 701 on the user interface 301, for example, using the toolbar 713, and list whether the subsequent nodes of the node exist in the output information browser 407.
  • the user can check the information of the constraint overlap nodes listed in the output information browser 407 and consider the possibility of establishing an immune procedure in the event that the node constraints 204 overlap in subsequent nodes.
  • the auxiliary design task module 306 can include associated data maintenance, inspection, and cleanup task modules.
  • the user can select the task module on the user interface 30, for example, using the toolbar 714 to verify the immunization program including the vaccine, the meta vaccine, the data format of the SG, the inter-data dependencies, the valid range of the data values, and the like.
  • the related data maintenance, inspection, and cleaning task modules of the auxiliary design task module 306 can also automatically complete the maintenance of the immune program in cooperation with other modules.
  • the associated data maintenance, inspection, and cleanup task module of the auxiliary design task module 306 can look up objects that depend on the vaccine, such as a meta-vaccine that relies on the vaccine, and Depending on the SG node, if an object dependent on the vaccine is found, a prompt warning message indicating the data dependency is displayed in the user interface 301, for example, in a pop-up session window manner, the user is requested to confirm the deletion operation. It should contain subjects who depend on the vaccine.
  • the immune program management module 302 can include a dynamic recipe, toolbar generation and management system based on the immune program related objects, which can be generated and managed based on the selected objects 403-406, 410-414 of the user. Some task menus and toolbars of the selected objects guide the user through some related tasks.
  • the immunization program publishing engine 308 is used for the publication of immunization programs in various formats.
  • the immunization program publication engine 308 can be integrated into the immunization program user interface 30.
  • the user can select, on the user interface 301, for example, using the toolbar 715, the publishing engine 308 to issue, convert, and output the immunization program in a format selected by the user.
  • the publishing engine 308 will read the data from the immune program storage 307, convert it to the selected format, and output the immune program, for example, as described later in conjunction with FIG.
  • the format of the publication of the immunization program for the average reader user; and the publication of the immunization program in XML document format for transmission to the vaccination information processing service system and used by the system [: users can choose single or several vaccines or meta-vaccines, single line or Several departments of ISG published. The user can change the default format of the immune program release, such as using the default format of the system's menu settings in the input interface 301.
  • FIG 8 is a schematic diagram of an ISG 800 issued in a graphical format in accordance with the present invention.
  • the ISG 800 can have multiple immune block diagrams 801 and a legend 803.
  • Each block diagram 801 can have one or more node tables 804; a node of the SG, fed as node 707, can correspond to a node table in block 801, such as node table 804; Show some or all of the constraints of the node it corresponds to.
  • Each block diagram 80 may have one or more annotations 802 for listing some of the information of the block diagram, such as information about the vaccine used in the block diagram, and the shared information between the node tables in the block diagram.
  • Figure 803 is used to illustrate the meaning of each character, symbol and graphic element in the frame 801.
  • FIG 9 is a data structure of a process state 1100 of a storage process for use in inoculation information processing in accordance with the present invention.
  • Process state 1100 can include a general state 1120 and states 1123 of the various systems; a recommended date range 1121 in the general state 1120. [ ⁇ 3 ⁇ 43 ⁇ ⁇ 1 ] is used to set the future vaccination recommendation date range of interest to the user, where T sian is the start date and T end is the due date; states 1124- 126 and 1128 - 1129 in process state 1100 may be The implementation of the list, the state L127 can be a Boolean variable, when it is TRUE, it indicates that the inoculation of the system has been completed, and when it is FALSE, it indicates that it has not been completed.
  • Figure 10 a is a block diagram showing a method for performing inoculation information processing using an ISG in the embodiment of the present invention.
  • the vaccinator information is received and the vaccinator information is processed.
  • step 201 the process state 1100 is initialized, including initialization states ⁇ 24- ⁇ 28, such as clearing states 1124-1126 and 1128 storage units, etc., and setting the system end identifier 1127 to FALSE, and the like.
  • step 1202 some of the pre-treatment tasks need to be performed so that the vaccination history of the vaccinator and the future vaccination required thereof can be processed step by step.
  • Each of the meta-vaccines contained in the vaccine is then injected and stored in the vaccination history i i24 of the corresponding line by the meta-vaccine and the inter-injection primordial injection, and can be sorted according to the injection time 1124 in the injection time;
  • 2 Check the time interval between the injections of the vaccination containing the attenuated inactivated vaccine Whether it meets the immunization program, non-conforming injections are invalid vaccinations. Injections and invalidation determined to be ineffective vaccination in the pretreatment are recorded in the evaluated injection list 1129.
  • the vaccination history in the vaccinator information and the vaccinations required in the future are processed on a case-by-case basis.
  • the treatment of a line should first assess the vaccination history of the line of the vaccinator 1124, and then determine the future vaccination of the line required by the vaccinator within the recommended date range 1121 and store the recommended vaccination 1126 in the line.
  • each department can have different processing methods. The method of processing a series will be described later in conjunction with Figure 10 b).
  • step 1204 some post-processing tasks need to be performed.
  • the following tasks are usually required: 1) Check the recommended interval between the recommended vaccinations for each of the attenuated inactivated vaccines included in the recommended vaccination 1126 and the vaccination history of the vaccinated person with attenuated inactivated vaccine Whether the time interval between injections meets the requirements of the immunization program; the recommended vaccination in which the time interval is not met will be adjusted, usually after the vaccination time of the recommended vaccination, until the delay between the vaccination and other detoxification
  • the time interval between the recommended vaccination of the live vaccine and the vaccination history of the vaccinator includes the time interval for the injection of the attenuated inactivated vaccine. The immunization schedule is not met.
  • the recommended vaccination is recorded; 2) Converting the vaccination in the recommended vaccination to vaccination, the conversion method is if a meta-vaccine corresponding to all components in the component list 216 of a vaccine 210 appears in the recommended vaccination, ⁇ If the vaccination time in the recommended vaccination of these meta-vaccinations is non-empty, use the vaccine and the time to produce a vaccine recommendation. Vaccination; Meta-vaccination that cannot be converted during the recommended vaccination should be recorded; 3) Generate a treatment report according to the treatment status 1100, for example, generate a vaccination history evaluation report according to the state 1128-1129 and determine whether to generate a recommendation report according to the status 127, such as generating a recommendation report. Generating a future vaccination recommendation report based on state 1126;
  • processing ends and processing report 1103 is returned.
  • FIG. 10 b) is a block diagram showing a flow of a processing method for a system according to an embodiment of the present invention.
  • the processing of a series begins at step 1211.
  • step 1212 all possible subsequent node sets 1125 are assigned as a set of all the starting nodes of the system.
  • steps 1213-1214 if there is an unevaluated injection in the vaccination history 1124, the vaccination history is evaluated.
  • the method of estimating the history of vaccination is to determine the vaccination history according to the vaccination time.
  • Each injection in 124 that does not appear in the evaluated injection list 1129 determines a node in the ISG of the system; Injecting to find a node, this injection should be an invalid vaccination.
  • the injection and evaluation results can be recorded in the department's evaluated injection list 1128 for generation Process the report.
  • steps 1215-1216 if the vaccination of the line has not been completed, the subsequent node required for the last node in the path determined by assessing the vaccination history 1124 of the line at step 1214 is used to derive the desired amount for the vaccinator. Future vaccination.
  • step 1217 the processing of the system ends and returns to the main flow control 1203.
  • a method for estimating the inoculation history of a vaccinator, 1124, which can be used in step 1214 to assess a vaccination history of a line the method having the following steps;
  • the unevaluated injection is taken in the vaccination history 1124 according to the vaccination time sequence; otherwise, the evaluation ends and the system is withdrawn; b) verifying that the injection satisfies all of the constraints of one of the subsequent node sets 1125; if so, the injection is a valid vaccination, adding the injection to the evaluated injection list 1128, continuing with c); Recording the injection as an invalid vaccination and adding the injection and the cause of the invalidation in the evaluated injection list 1128, transferring to execution a;
  • step b) if there is priority information in the subsequent node information, when checking whether an injection satisfies all the constraints of one of the subsequent node sets 1125, the priority should be high.
  • the low priority takes each node to check whether the injection satisfies all the constraints of the node taken. If there is no priority information in the subsequent node information, each node can be taken in any order to check whether the injection satisfies all the constraints of the node taken.
  • Embodiments of the present invention provide a method for a vaccinator to recommend a future vaccination required within the recommended date of the model, which may be used in step 1216 to recommend a future vaccination of a line, if a future vaccination of the line is recommended There is no need to go to the termination point of the ISG of the system or to use the termination point of the ISG of the system but there is no optional vaccination constraint 218.
  • the method has the following steps - a) if in the subsequent node set 1125 If there is a node that has not been used for recommendation, then in the set 1125, ⁇ is used for the recommended node; otherwise, the recommended processing is ended;
  • the method of checking the constraint condition related to the time range may be determining [ ⁇ , ⁇ and the intersection of the time-range constraint conditions of the node [, 3 ⁇ 4, and judging Whether the intersection is empty.
  • the constraints related to the time range are mainly: License validity period range 220, effective date range 221, age range 219, birth period 0 range, and recommended age range, recommended time interval, minimum time interval I, etc. Condition; if the time intersection [ ⁇ ⁇ ] is not empty, the constraint related to the time norm is satisfied, otherwise it is not satisfied. If the above time intersection [T rf , T n ] has been determined in step b), then this value can be used in step c).
  • a recommendation is made for the vaccinator on the recommended date.
  • One method of future vaccination required is to first use the vaccinator information to check if the optional vaccination 218 constraint for the endpoint is met; if satisfied, the endpoint is processed without the optional vaccination 218 constraint, continue to This endpoint is used for the recommendation of the department; if not, the end identifier 1127 of the system is set to indicate that the immunization of the system has been completed, and the recommendation process is terminated.
  • the recommended future vaccination depends on the recommended phase 0 range 1121 and can be used as a recommended node, so the recommended future vaccination may include multiple vaccines and different vaccination periods. To narrow down the specification, some other conditions can be used, such as using priority to determine the trade-off or prioritization of each node when it is used for recommendation, and defining a narrower recommended date range 1121, and so on.
  • Another embodiment of the present invention provides a method for optimizing the cut-off age ⁇ ⁇ of a series as follows - after the steps in the processing method described in FIG. 0b), after the step 211 and before the step 1212, the inoculator is first tested. Whether the age has exceeded the cut-off age ⁇ ⁇ ; if the vaccination does not need the vaccination, the vaccination can withdraw from the department; otherwise, the system still needs to be treated, and the feeding step is as follows.
  • This method is suitable for only need
  • the advantage is that they can save processing time and make it clear that the vaccinator does not need the vaccination.
  • the disadvantage is that this method does not give an assessment of the system. For customers who need to evaluate the vaccination history, the following methods can be used.
  • Another embodiment of the present invention provides a method for optimizing the processing of a series of cutoff ages ⁇ ⁇ .
  • it is first checked whether the age of the vaccinator has exceeded the cut-off age A T , and if the vaccinator does not need the vaccination, the vaccination may withdraw from the treatment; otherwise, Recommended processing, for example, continue with the steps 216.
  • the above methods can be implemented in a computer software program and combined into a module or architecture application program interface (API) for convenient use.
  • the method or function for processing the vaccination information may include an application interface function Report process (ClientInformation client), which accepts the vaccinator information Clientlnformation, processes and returns the processed report Report.
  • ClientInformation client an application interface function Report process
  • the computer software program implementing the above method is deployed on a computer readable medium, such as a hard disk, and the functions of the method of processing the vaccination information described above can be provided when the instructions of the program are loaded into the memory of the computer and executed.
  • One implementation of the present invention is a method of updating an SG, using: SCAD to update the SG, issuing the ISG, to an application system that processes the vaccination information using the ISG, the method comprising the steps of:

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Abstract

L'invention concerne un graphe de procédure d'immunisation et un procédé de construction de ce graphe et un procédé et un système de traitement d'informations d'inoculation. Dans la présente invention, une procédure d'immunisation visuelle d'un digraphe est utilisée, l'inoculation d'une dose est indiquée par un nœud dans le digraphe, et le nœud est relié à un autre nœud de l'inoculation de dose suivante par une ligne vectorielle dans le digraphe. Le procédé de traitement d'informations d'inoculation comprend : la recherche d'un ou de plusieurs trajets correspondant à des enregistrements d'inoculation d'inoculateurs dans le digraphe de programme d'immunisation et la recommandation d'une future inoculation aux inoculateurs conformément aux trajets. Par l'application de la présente invention, un temps pour répercuter des modifications du programme d'immunisation dans le système de traitement d'informations d'inoculation est raccourci, et la grande disponibilité du système de traitement d'informations d'inoculation est améliorée.
PCT/CN2012/083567 2011-12-06 2012-10-26 Graphe de procédure d'immunisation et procédé de construction de ce graphe et procédé et système de traitement d'informations d'inoculation WO2013082978A1 (fr)

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