WO2013073929A8 - Method and apparatus for detecting nucleic acid variation(s) - Google Patents

Method and apparatus for detecting nucleic acid variation(s) Download PDF

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Publication number
WO2013073929A8
WO2013073929A8 PCT/MY2012/000273 MY2012000273W WO2013073929A8 WO 2013073929 A8 WO2013073929 A8 WO 2013073929A8 MY 2012000273 W MY2012000273 W MY 2012000273W WO 2013073929 A8 WO2013073929 A8 WO 2013073929A8
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid variation
detecting nucleic
detecting
relates
Prior art date
Application number
PCT/MY2012/000273
Other languages
French (fr)
Other versions
WO2013073929A1 (en
Inventor
Yang Ming POH
Soo Heong BOON
Ying Wah LEE
Original Assignee
Acgt Intellectual Limited
ACGT, Sdn Bhd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acgt Intellectual Limited, ACGT, Sdn Bhd filed Critical Acgt Intellectual Limited
Publication of WO2013073929A1 publication Critical patent/WO2013073929A1/en
Publication of WO2013073929A8 publication Critical patent/WO2013073929A8/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression

Abstract

The invention relates to a method for detecting at least one nucleic acid variation based on the ratio of corrected signal intensities of at least two differentially labelled probes capable of detecting the nucleic acid variation. The invention also relates to an apparatus for performing the method.
PCT/MY2012/000273 2011-11-15 2012-11-14 Method and apparatus for detecting nucleic acid variation(s) WO2013073929A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MYPI2011005518 2011-11-15
MYPI2011005518 2011-11-15

Publications (2)

Publication Number Publication Date
WO2013073929A1 WO2013073929A1 (en) 2013-05-23
WO2013073929A8 true WO2013073929A8 (en) 2014-01-09

Family

ID=48429916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/MY2012/000273 WO2013073929A1 (en) 2011-11-15 2012-11-14 Method and apparatus for detecting nucleic acid variation(s)

Country Status (3)

Country Link
AR (1) AR088867A1 (en)
TW (1) TW201323615A (en)
WO (1) WO2013073929A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10396405B2 (en) * 2014-11-10 2019-08-27 Te Connectivity Corporation Bus bar for a battery connector system
CN107533591A (en) * 2015-04-01 2018-01-02 株式会社东芝 Genotype decision maker and method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020025519A1 (en) * 1999-06-17 2002-02-28 David J. Wright Methods and oligonucleotides for detecting nucleic acid sequence variations
CA2594730A1 (en) * 2005-01-13 2006-07-20 Progenika Biopharma, S.A. Methods and products for in vitro genotyping
US20090011944A1 (en) * 2007-02-21 2009-01-08 Valtion Teknillinen Tutkimuskekus Method and test kit for detecting nucleotide variations
US20090062138A1 (en) * 2007-08-31 2009-03-05 Curry Bo U Array-based method for performing SNP analysis
US20110003301A1 (en) * 2009-05-08 2011-01-06 Life Technologies Corporation Methods for detecting genetic variations in dna samples

Also Published As

Publication number Publication date
WO2013073929A1 (en) 2013-05-23
AR088867A1 (en) 2014-07-16
TW201323615A (en) 2013-06-16

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