WO2013073210A1 - Prostatic hyperplasia model and prostate surgery simulator - Google Patents

Prostatic hyperplasia model and prostate surgery simulator Download PDF

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WO2013073210A1
WO2013073210A1 PCT/JP2012/057574 JP2012057574W WO2013073210A1 WO 2013073210 A1 WO2013073210 A1 WO 2013073210A1 JP 2012057574 W JP2012057574 W JP 2012057574W WO 2013073210 A1 WO2013073210 A1 WO 2013073210A1
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component
gland
prostate
prostatic hypertrophy
lobe
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PCT/JP2012/057574
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French (fr)
Japanese (ja)
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公志 松田
秀文 木下
幸雄 岡本
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学校法人関西医科大学
株式会社いわさき
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/30Anatomical models
    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine

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  • the present invention relates to a prostatic hypertrophy model and a prostatic surgery simulator for acquiring a surgical technique for treating prostatic hypertrophy.
  • TUR-P transurethral prostatectomy
  • the prostate (inner gland) bulging in front of the bladder is excised with an electric knife, and the urethral stricture portion is expanded.
  • the above TUR-P has the advantage that the abdomen is not damaged because it is performed using an endoscope.
  • the operation is performed while slicing the enlarged portion of the prostate with an electric knife, the enlargement of the prostate is advanced.
  • the reflux liquid may enter the circulatory system from the vein and cause hyponatremia.
  • ⁇ 1 blockers are the first choice in recent years and the period of medical treatment has been prolonged, very large prostatic hypertrophy is often the target of surgery, and the complications of these TUR-Ps are It has become a big problem.
  • HoLEP holmium laser enucleation of the prostate
  • HoLEP is a method of exfoliating the surgical capsule and adenoma under the endoscope to enucleate the prostate gland, and is an excellent surgical method for benign prostatic hyperplasia. Is actually improving their skills while performing actual surgery under the guidance of skilled doctors. Therefore, the applicant of the present application has developed a simulation model for prostate surgery that can faithfully reproduce HoLEP surgery (see Patent Document 1).
  • the present invention has been made in consideration of the problems in the conventional simulation model as described above, and is a prostatic hypertrophy model that reproduces the HoLEP operation and can simulate the nuclear enucleation operation of the prostate with almost the same feeling as the actual operation. And a prostate surgery simulator.
  • the present invention has two forms: a prostatic hypertrophy model and a prostate surgery simulator using the model.
  • the first form has an inner gland part imitating an enlarged inner gland in the prostate, and an outer gland membrane part imitating an outer gland membrane,
  • the outer gland membrane part covers the outer peripheral surface of the inner gland component,
  • a ureteral stricture is formed in the inner gland component,
  • the inner gland component and the outer gland membrane portion are connected by an adhesive layer, and the adhesive layer is a prostatic hypertrophy model composed of a mixture of gluten and glycerin.
  • the inner gland component is a combination of a right lobe component that mimics the right lobe, a left lobe component that mimics the left lobe, and a middle lobe component that mimics the middle lobe.
  • the inner gland component and the outer gland membrane can be constituted by heating a mixture of gluten, starch, glycerin and water.
  • a second aspect of the present invention is a prostate hypertrophy model having the above-described configuration, It is a prostate surgery simulator configured by a bladder part that has a recess capable of attaching and detaching the prostatic hypertrophy model and a liquid storage part communicating with the ureteral stenosis part and imitating a bladder.
  • the ureteral stenosis portion of the prostatic hypertrophy model mounted in the recess can be configured to communicate with a urethral component simulating a urethra.
  • the liquid storage part can be filled with an electrolyte such as water or physiological saline.
  • FIG. 4 is a view corresponding to FIG. 3 showing a state where the prostate cartridge is removed. It is explanatory drawing which showed the prostate and its surrounding tissue. It is explanatory drawing which shows the state which the prostate enlarged. It is the figure which showed the structure of the prostate model, (a) is a top view, (b) is a side view, (c) is AA arrow sectional drawing of Fig.7 (a). It is sectional drawing which showed the modification of the prostate component. (a)-(d) is process drawing explaining the training method using the prostate surgery simulator of this invention.
  • FIG. 1 is a perspective view showing the overall configuration of a prostate surgery simulator (hereinafter abbreviated as a simulator) of the present invention.
  • a simulator 1 is composed of a box-shaped case 2 and a simulator main body 3 installed on the case 2.
  • the simulator body 3 has a shape that is obtained by cutting the lower abdomen.
  • the simulator body 3 is formed of, for example, a polyester resin fiber reinforced with glass fiber.
  • a urethra part 4 made of silicon rubber that imitates the urethra and its surrounding tissue is fitted in the front part of the simulator body 3.
  • the urethral component 4 is provided with a cylindrical urethra portion 4b (see FIG. 2) having an endoscope insertion port 4a.
  • XX ′ indicates the front-rear direction
  • YY ′ indicates the left-right direction
  • ZZ ′ indicates the up-down direction.
  • the front side corresponds to the urethra side and the rear side corresponds to the bladder side.
  • An opening 3a is provided in the upper part of the simulator body 3, and a prostate cartridge described later can be mounted or removed through this opening 3a.
  • a bladder part 5 (see FIG. 2) simulating a bladder is disposed in the simulator body 3.
  • a caster 6 for facilitating the movement of the simulator 1 is provided on the bottom surface of the case 2.
  • FIG. 2 is a cross-sectional view showing the internal configuration of the simulator.
  • the bladder part 5 is formed in a container shape so as to function as a liquid storage part.
  • the bladder part 5 stores the reflux water W as a liquid storage with a prostate cartridge attached.
  • a container 5 a for receiving the bladder part 5 is provided outside the bladder part 5, and a drain port 5 b provided at the rear part of the container 5 a is connected to the intake port 9 a of the reflux device 9 via the intake pipe 7.
  • the reflux water W includes an electrolytic solution such as water or physiological saline.
  • the reflux device 9 includes a filter for filtering the reflux water W used in the simulation and a pump for sending the filtered reflux water W to the bladder component 5 from the discharge port 9b. Specifically, the reflux water W overflowing the bladder part 5 is taken into the reflux device 9 from the drain port 5b through the intake pipe 7 and filtered by the filter, and the filtered reflux water W is branched into two. , 8b, respectively.
  • One water supply pipe 8 a communicates the discharge port 9 b of the reflux device 9 and the front empty chamber 10 a of the prostate cartridge 10, and returns the reflux water W into the bladder part 5 through a gap between the urethra portion 4 b of the prostate cartridge 10. It is like that.
  • the other water supply pipe 8b connects the discharge port 9b and the outer cylinder device 14 housing the endoscope 30, and the reflux water W discharged from the water supply pipe 8b is connected to the inner wall of the outer cylinder device 14 with the inner wall. It flows through the gap with the endoscope 30.
  • the reflux water W that is sent to the outer cylinder device 14 and discharged in a cylindrical shape from around the endoscope 30 is for expanding the field of view of the endoscope 30.
  • a water receiver 2a is provided at the front part of the simulator body 3, and receives the reflux water W leaked from the urethral component 4, and guides it to the drain tank 9c through the drain pipe 2b.
  • a cavity (recess) 5c into which the prostate cartridge 10 can be fitted is formed in the front part of the bladder part 5.
  • the portion 4b is inserted into the front through hole 10b of the prostate cartridge 10.
  • reference numeral 5d denotes a stopper for holding the prostate cartridge 10 in the cavity 5c.
  • FIG. 3 is an explanatory view of the simulator body 3 as viewed from the rear, and shows a state where the prostate cartridge 10 is mounted.
  • FIG. 4 shows a state in which the prostate cartridge 10 is removed from the cavity 5c, and the urethra 4b of the urethral component 4 appears on the back side of the cavity 5c.
  • the configuration of the prostate cartridge 10 will be described. Before that, enlargement of the prostate will be described.
  • FIG. 5 shows the prostate and surrounding tissues.
  • the prostate 20 exists so as to surround the urethra 22 in the vicinity of the outlet of the bladder 21, and has a two-layer structure having the size of a walnut.
  • the inner portion is called the inner gland 20a and the outer portion is called the outer gland membrane 20b. Under normal conditions, the inner gland and the outer gland membrane have almost the same thickness.
  • 23 is a seminal vesicle and 24 is a urethral sphincter.
  • the inner gland 20a expands to become an adenoma
  • the outer gland membrane 20b expands, as if the contents of the mandarin orange (inner gland 20a) and the skin (outer gland membrane 20b).
  • the inner gland 20a enlarges and presses the urethra 22 to cause difficulty in urination and frequent urination, so that the inner gland 20a portion is removed in the treatment by surgery.
  • FIG. 7 shows the structure of the prostate cartridge.
  • FIG. 7A is a plan view
  • FIG. 7B is a side view
  • FIG. 7C is a cross-sectional view taken along the line AA in FIG. is there.
  • the prostate cartridge 10 is composed of a cartridge outer frame 11 and a prostate part 12 which is accommodated in the cartridge outer frame 11 and imitates an enlarged prostate.
  • the prostate cartridge 10 is replaced every time a simulation is performed. It has become.
  • the cartridge outer frame 11 is made of an elastic body formed of a material such as gelatin, silicone rubber, or urethane resin in a bottomed cylindrical shape, and the urethra portion 4b of the urethral component 4 is inserted into the front portion thereof.
  • the front through-hole 10b is provided.
  • the prostate part 12 is composed of an inner gland part and an outer gland membrane part, and the inner gland parts are a right lobe part 12a imitating an enlarged right lobe, a left lobe part 12b imitating an enlarged left lobe, and a middle lobe. It is comprised from three parts of the middle leaf part 12c which imitated.
  • a stenosis passage (ureter stenosis) U is intentionally formed between the right lobe component 12a and the left lobe component 12b.
  • the right side wall 12d of the right lobe component 12a is connected to the outer gland membrane portion 12f via an adhesive layer 12e simulating mucous membranes.
  • the left side wall 12g of the left lobe component 12b is connected to the outer gland membrane portion 12h via the adhesive layer 12e.
  • the middle lobe component 12c disposed below the right lobe component 12a and the left lobe component 12b (on the right side in FIG. 7 (a)) is connected to the outer gland membrane portions 12f and 12h via the adhesive layer 12e ′, The right lobe component 12a and the left lobe component 12b are also connected.
  • the prostate part 12 having the above-described configuration is assembled so as to surround the narrowed passage U in the cartridge outer frame 11. Then, after being mounted in the cavity 5 c of the bladder part 5, it is immersed in the reflux water W stored in the bladder part 5.
  • the right leaf part 12a, the left leaf part 12b, and the middle leaf part 12c are 40 to 70 parts by mass of powdered vacuum-dried gluten containing wheat as a main raw material, 0 to 20 parts by mass of starch, 30 to 50 parts by mass of glycerin, and water 5 A mixture of parts by mass is formed into a lump by heating at 100 to 120 ° C. for 60 to 90 minutes. Glycerin is used as an adjuster for softening the hardness of the inner gland component.
  • the outer gland membrane portions 12f and 12h are prepared by mixing powdery vacuum-dried gluten 35 to 65 parts by mass, starch 0 to 35 parts by mass, glycerin 40 to 60 parts by mass and water 5 to 10 parts by mass. It is formed into a bag shape by heating at 75 ° C. for 75 minutes.
  • the pressure-sensitive adhesive layer 12e can be obtained by mixing powdery vacuum-dried gluten and glycerin. Since gluten only solidifies and loses elasticity, the elasticity (stickiness) is maintained by adding glycerin.
  • the amount of glycerol present can be selected in the range of 0.7 to 1.4 times the total amount of gluten and glycerol, preferably 0.9 to 1.1 times, and most preferably 1.0 times. .
  • the result that the mixture ratio of gluten and glycerin is 1.0: 1.0, specifically, the mixture of 50 parts by mass of vacuum-dried gluten and 50 parts by mass of glycerin is the closest to the living body. Yes.
  • the amount of glycerin is more than 1.0 times and 1.4 times or less, it can be easily excised with a laser having a weak output. Therefore, this blending ratio can be used for a practitioner who is not accustomed to the sense of distance between the target site and the laser irradiation unit.
  • the amount of glycerin is 0.7 times or more and less than 1.0 times, the stickiness is strong, and it is necessary to have a technique for increasing the output of the laser to keep the irradiation distance short and constant. There is a risk of removing the outer gland. Therefore, those with this blending ratio can be intended for advanced users. Furthermore, if the amount of glycerin is too small, less than 0.7 times, the time required for excision with the laser becomes long, which is inconvenient that it differs from the actual surgical sensation in the human body, 1.4 times. If the amount is too much, it cannot be used because it collapses at the moment of laser irradiation. Further, when starch is used in addition to gluten and glycerin, for example, turbidity is generated during laser irradiation and visibility is deteriorated. Therefore, only gluten and glycerin are used for the adhesive layer 12e.
  • the gluten used in the present embodiment is preferably gluten mainly composed of wheat or soybean as described above, and one that does not contain sugar is recommended so that it does not burn even when holmium yag laser is applied.
  • the pressure-sensitive adhesive layer 12e the pressure-sensitive adhesive material obtained by the above blending can be formed in a film shape, and can also be formed by applying it in a streak shape. Alternatively, it may be formed by pasting a sheet or net formed in advance.
  • a silicon resin-based material has a problem that it is burnt during laser irradiation, and is excluded because only the laser irradiated portion emits red light due to the high combustion temperature of the silicon resin.
  • various materials were tested, and it was confirmed that the most realistic feel was obtained when water was added based on gluten and glycerin.
  • FIG. 8 is a cross-sectional view showing a modified example of the prostate part, and corresponds to FIG.
  • the prostate component 13 shown in the figure has a gap S between the right lobe component 13a and the outer gland membrane portion 13b, and the right lobe component 13a and the outer gland membrane portion 13b are partially separated in the gap S.
  • the adhesive sheet 13c to be connected is laminated with a thickness of 2 to 6 mm.
  • the adhesive sheets 13c are all made of the same material (gluten + glycerin) and have elasticity and adhesiveness like soft rubber. Therefore, if it is pushed in the direction of arrow F, it can be deformed in the thickness direction. This is in response to the request that it can be moved forward and backward (in the direction of the urethra component 4-blade component 5) by being pushed by the endoscope, as in the case of actual treatment.
  • the left lobe component 13d is similarly provided with a gap S, and similarly, the left lobe component 13d and the outer gland membrane portion 13b are connected via the adhesive sheet 13c.
  • a thin tube is placed instead of the vascular tissue around the connecting part of the outer gland membrane part and the prostate part, or around the connecting part, and a red liquid is poured into the tube, holmium It will also be possible to experience hemostasis using a yag laser.
  • the HoLEP endoscope 30 is inserted from the endoscope insertion port 4a (see FIG. 2) of the urethral component 4, and the endoscope 30 is inserted into the bladder component 5 through the narrowed passage U. insert.
  • the right lobe component 13a, the left lobe component 13b, the middle lobe component 12c (see FIG. 7A), and the bladder component 5 are observed with the inserted endoscope 30.
  • the internal gland of the prostate is composed of a right lobe, a left lobe, and a middle lobe. When performing enucleation training, first, the middle lobe part imitating the middle lobe is enucleated.
  • the adhesive layer 12e ′ (see FIG. 7A) is incised by a holmium yag laser to find a boundary layer between the middle lobe component 12c and the outer gland membrane portions 12f and 12h.
  • the holmium yag laser has a high absorption rate in water or saline and other electrolytes, and the tissue can be excised at a distance of 2.0 mm or less, and at the same time, hemostasis is performed by burning the tissue. If the tip of the tube is separated from the tissue by 5.0 mm, the tissue is not affected.
  • the prostate component 12 of the present invention includes the adhesive layers 12e and 12e 'imitating the mucous membrane to be excised by the holmium yag laser, the laser fiber tip of the holmium yag laser is brought close to the mucosal layers 12e and 12e'.
  • the holmium yag laser is irradiated from a close distance to the adhesive layer 12e composed of gluten and glycerin, the network structure of the adhesive layer 12e is cut and changed into a lint-like shape. This situation is very similar to the state in which the mucous membrane between the inner gland and the outer gland membrane is cut with a laser, and you can experience the sensation of peeling the inner gland.
  • the adhesive layer 12e ′ is cut out on both sides of the middle lobe component 12c from the portion corresponding to the bladder neck of the bladder component 5.
  • the middle lobe component 12c is attached only at the portion corresponding to the bladder neck, the attached portion is cut off to release the middle lobe component 12c into the bladder component 5.
  • enucleation training for the right lobe component 12a is performed. Note that enucleation training may be performed from the left lobe component 12b.
  • the right lobe component 12a is detached from the outer gland membrane portion 12f by irradiating the boundary layer between the right lobe component 12a and the outer gland membrane portion 12f, that is, the adhesive layer 12e, with the holmium yag laser 31. To go. At this time, peeling is performed from the urethra side where the sphincter is located toward the bladder part 5 side and the abdomen side. The bladder part 5 is not shown.
  • the adhesive layer 12e is peeled along the outline of the right lobe component 12a from the ventral side to the dorsal side or from the dorsal side to the ventral side, and the peeled portion is made continuous.
  • the adhesive layer 12e between the outer gland membrane 12f and the right lobe component 12a connected from the ventral side to the dorsal side is evenly peeled from the urethra side toward the bladder component 5 on the ventral dorsal side. As this separation progresses, the right lobe component 12a is attached only at the bladder neck (see FIG. 9C).
  • FIG.9 (d) the part connected to the bladder neck part is cut off, the right lobe part 12a is released, and the enucleation training of the right lobe part 12a is completed.
  • Enucleation training for the left lobe component 12b is also performed in the same manner as the enucleation training for the right lobe component 12a, thereby completing the enucleation training for the inner gland.
  • a nephroscope (Struts) is inserted from the front through-hole 10b, and the glandularized nucleus in the bladder part 5 is cut and collected using a molcerator. Next, the urinary catheter of about 20 Fr is placed from the front through-hole 10b to complete the training.
  • the prostatic hypertrophy model and the prostatic surgery simulator of the present invention can be used as a means for acquiring a surgical technique for treating prostatic hypertrophy.

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Abstract

A prostatic hyperplasia model, which enables the reproduction of HoLEP surgery and allows an operator to simulate enucleation of the prostate as if s/he were conducting the actual surgery, said prostatic hyperplasia model being characterized by comprising prostatic inner gland parts (12a, 12b) simulating enlarged inner glands in the prostate, an outer gland membrane part (12f) covering the outer peripheral surface of the inner gland parts and simulating the outer gland membrane, and a ureteral stricture part (U) formed within the inner gland parts, wherein the inner gland parts are bonded to the outer gland membrane part via adhesive layers (12e, 12e'), and these adhesive layers are formed of a mixture of gluten with glycerin.

Description

前立腺肥大モデルおよび前立腺手術シミュレーターProstatic hypertrophy model and prostate surgery simulator
 本発明は、前立腺肥大症を治療する手術手技を習得するための前立腺肥大モデルおよび前立腺手術シミュレーターに関するものである。 The present invention relates to a prostatic hypertrophy model and a prostatic surgery simulator for acquiring a surgical technique for treating prostatic hypertrophy.
 現在、日本人男性の約80%が80歳までに前立腺肥大症になるといわれている。前立腺肥大症において、薬物治療で改善が望めない場合には手術による治療が必要になる。
 最もスタンダードな手術方法は、経尿道的前立腺切除術(TUR-P)と呼ばれる方法であり、内視鏡で患部を見ながら切除が行われる。
 具体的には、まず、内視鏡を尿道出口から挿入し、膀胱へ向けて移動させ、膀胱手前の前立腺をモニターに映し出す。映し出された肥大前立腺は、尿道の内側に向けて膨出しているため、その部分の尿道が細くなって見える。
Currently, about 80% of Japanese men are said to have benign prostatic hyperplasia by the age of 80. In the case of prostatic hypertrophy, if treatment cannot be improved by drug treatment, surgical treatment is necessary.
The most standard surgical method is a method called transurethral prostatectomy (TUR-P), in which resection is performed while viewing the affected area with an endoscope.
Specifically, first, an endoscope is inserted from the urethral outlet, moved toward the bladder, and the prostate in front of the bladder is displayed on the monitor. The enlarged prostate that is projected bulges toward the inside of the urethra, so the urethra of that part appears to be thinner.
 次に、膀胱の手前で膨出している前立腺(内腺)を電気メスで切除し、尿道狭窄部分を拡張する。
 上記したTUR-Pは、内視鏡を用いて行われるため腹部に傷がつかないという利点がある反面、電気メスで前立腺の肥大部分を細切しながら手術を行うため、前立腺の肥大が進んでいる場合には出血が多いという欠点がある。
 また、一般的には還流液として電解質を含まない液体を用いるため、還流液が静脈から循環系に入り、低ナトリウム血症をきたすこともある。特に、近年ではα1遮断薬が第一選択とされ、内科的治療を行う期間が長期化しているため、非常に大きな前立腺肥大症が手術対象になることが多く、これらTUR-Pにおける合併症は大きな問題となっている。
Next, the prostate (inner gland) bulging in front of the bladder is excised with an electric knife, and the urethral stricture portion is expanded.
The above TUR-P has the advantage that the abdomen is not damaged because it is performed using an endoscope. On the other hand, since the operation is performed while slicing the enlarged portion of the prostate with an electric knife, the enlargement of the prostate is advanced. There is a disadvantage that there is a lot of bleeding if it is.
In general, since a liquid not containing an electrolyte is used as the reflux liquid, the reflux liquid may enter the circulatory system from the vein and cause hyponatremia. In particular, since α1 blockers are the first choice in recent years and the period of medical treatment has been prolonged, very large prostatic hypertrophy is often the target of surgery, and the complications of these TUR-Ps are It has become a big problem.
 このような状況において、内視鏡手術の概念としては、まったく異なった方法が開発された。それがホルミウムレーザー前立腺核出術(holmium laser enucleation of the prostate;HoLEP)である。
 HoLEPは内視鏡下で外科的被膜と腺腫との間を剥離し、前立腺内腺を核出するという方法であり、前立腺肥大症に対し非常に優れた手術方法であるが、その手技の習得は、熟練医師の指導のもとに実際の手術を行いながら技術を高めているのが実情である。
 そこで、本願出願人は、HoLEP手術を忠実に再現することができる前立腺手術用シミュレーションモデルを開発している(特許文献1参照)。
Under such circumstances, a completely different method has been developed as the concept of endoscopic surgery. That is holmium laser enucleation of the prostate (HoLEP).
HoLEP is a method of exfoliating the surgical capsule and adenoma under the endoscope to enucleate the prostate gland, and is an excellent surgical method for benign prostatic hyperplasia. Is actually improving their skills while performing actual surgery under the guidance of skilled doctors.
Therefore, the applicant of the present application has developed a simulation model for prostate surgery that can faithfully reproduce HoLEP surgery (see Patent Document 1).
特開2011-85689号公報JP 2011-85689 A
 上記前立腺手術用シミュレーションモデルの開発により、内腺と外腺膜の境界を確認しながらホルミウムレーザーでその境界部分を切除するといったHoLEP手術のシミュレーションが可能になった。
 しかしながら現状では、ホルミウムレーザーの操作方法の習得にとどまらず、前立腺の内腺を模した内腺部品と外腺膜を模した外腺膜部との間の境界層を剥離する際のレーザー操作感覚や、モニターに映し出される境界部分の切除映像を実際さながらに近づけたいといった、さらに高度な要望がシミュレーションモデルに求められている。
 また、前立腺核出手術では前立腺の手前側に圧力を加えながら境界層を剥離するという操作も行われるため、内腺部品はある程度の抵抗を持って変位できることが望ましい。
With the development of the simulation model for prostate surgery, it has become possible to simulate HoLEP surgery in which the boundary between the inner gland and the outer gland membrane is confirmed and the boundary is removed with a holmium laser.
However, at present, it is not limited to learning how to operate the holmium laser, and the laser operating sensation when peeling the boundary layer between the inner gland component that mimics the prostate gland and the outer gland membrane that mimics the outer gland membrane In addition, there is a need for simulation models that are more sophisticated, such as making the cut-out image of the boundary portion displayed on the monitor closer to the actual situation.
Further, in prostate enucleation surgery, an operation of peeling the boundary layer while applying pressure to the front side of the prostate is also performed. Therefore, it is desirable that the inner gland component can be displaced with a certain amount of resistance.
 本発明は以上のような従来のシミュレーションモデルにおける課題を考慮してなされたものであり、HoLEP手術を再現し前立腺の核出操作を実際の手術とほぼ同じ感覚でシミュレーションすることができる前立腺肥大モデルおよび前立腺手術シミュレーターを提供するものである。 The present invention has been made in consideration of the problems in the conventional simulation model as described above, and is a prostatic hypertrophy model that reproduces the HoLEP operation and can simulate the nuclear enucleation operation of the prostate with almost the same feeling as the actual operation. And a prostate surgery simulator.
 本発明は前立腺肥大モデルとそれを用いた前立腺手術シミュレーターとの二つの形態がある。 The present invention has two forms: a prostatic hypertrophy model and a prostate surgery simulator using the model.
 第一の形態は、前立腺における肥大した内腺を模した内腺部品と、外腺膜を模した外腺膜部とを有し、
 上記外腺膜部は上記内腺部品の外周面を被覆しており、
 上記内腺部品内に尿管狭窄部が形成されており、
 上記内腺部品と上記外腺膜部とが粘着層によって接続され、その粘着層が、グルテンとグリセリンとの混合物から構成されている前立腺肥大モデルである。
 上記前立腺肥大モデルにおいて、上記内腺部品は、右葉を模した右葉部品と、左葉を模した左葉部品と、中葉を模した中葉部品とを組み合わせたものからなり、上記中葉部品はさらに粘着層を介して上記右葉部品と上記左葉部品とに跨がって接続されているものである。
 また、上記粘着層における上記グルテンと上記グリセリンの混合割合はそれぞれ50質量部であることが好ましい。
 また、上記粘着層における上記グルテンと上記グリセリンの合計量に対し、グリセリンの存在量は0.7~1.4倍とすることが好ましい。
 また、上記内腺部品および上記外腺膜部は、グルテン、澱粉、グリセリン、水との混合物を加熱したものから構成することができる。
The first form has an inner gland part imitating an enlarged inner gland in the prostate, and an outer gland membrane part imitating an outer gland membrane,
The outer gland membrane part covers the outer peripheral surface of the inner gland component,
A ureteral stricture is formed in the inner gland component,
The inner gland component and the outer gland membrane portion are connected by an adhesive layer, and the adhesive layer is a prostatic hypertrophy model composed of a mixture of gluten and glycerin.
In the prostatic hypertrophy model, the inner gland component is a combination of a right lobe component that mimics the right lobe, a left lobe component that mimics the left lobe, and a middle lobe component that mimics the middle lobe. Furthermore, it is connected across the right lobe component and the left lobe component via an adhesive layer.
Moreover, it is preferable that the mixing ratio of the said gluten and the said glycerol in the said adhesion layer is 50 mass parts, respectively.
The amount of glycerin is preferably 0.7 to 1.4 times the total amount of gluten and glycerin in the adhesive layer.
Further, the inner gland component and the outer gland membrane can be constituted by heating a mixture of gluten, starch, glycerin and water.
 本発明の第二の形態は、上記構成を有する前立腺肥大モデルと、
 上記前立腺肥大モデルを着脱し得る凹部と、上記尿管狭窄部と連通する貯液部とを有し膀胱を模した膀胱部品とから構成されている前立腺手術シミュレーターである。
 上記前立腺手術シミュレーターにおいて、上記凹部に装着された上記前立腺肥大モデルの尿管狭窄部は、尿道を模した尿道部品と連通するように構成することができる。
 また、上記貯液部には水、または生理食塩水等の電解液を充填することができる。
 また、上記貯液部内の貯液を濾過し上記貯液部に還流させる還流装置を備えることが好ましい。
A second aspect of the present invention is a prostate hypertrophy model having the above-described configuration,
It is a prostate surgery simulator configured by a bladder part that has a recess capable of attaching and detaching the prostatic hypertrophy model and a liquid storage part communicating with the ureteral stenosis part and imitating a bladder.
In the prostate surgery simulator, the ureteral stenosis portion of the prostatic hypertrophy model mounted in the recess can be configured to communicate with a urethral component simulating a urethra.
Further, the liquid storage part can be filled with an electrolyte such as water or physiological saline.
Moreover, it is preferable to provide a reflux device for filtering the liquid stored in the liquid storage part and refluxing it to the liquid storage part.
 本発明によれば、HoLEP手術を再現し、前立腺の内腺を模した内腺部品と外腺膜を模した外腺膜部との間の境界層を剥離する際のレーザー操作感覚をトレーニングすることができ、また、モニターに映し出される境界部分の切除映像を実際さながらに再現することができる。 According to the present invention, HoLEP surgery is reproduced, and the laser operation sensation is trained when the boundary layer between the inner gland part imitating the internal gland of the prostate and the outer gland membrane part imitating the outer gland membrane is peeled off. In addition, the cut-out image of the boundary portion projected on the monitor can be reproduced as it is.
本発明の前立腺手術シミュレーターの全体構成を示す斜視図である。It is a perspective view which shows the whole structure of the prostate surgery simulator of this invention. 図1の前立腺手術シミュレーターの内部構成を示す断面図である。It is sectional drawing which shows the internal structure of the prostate surgery simulator of FIG. 前立腺カートリッジ装着状態を、シミュレーター本体の後方から見た斜視図である。It is the perspective view which looked at the prostate cartridge mounting state from the back of a simulator main part. 前立腺カートリッジを取外した状態を示す図3相当図である。FIG. 4 is a view corresponding to FIG. 3 showing a state where the prostate cartridge is removed. 前立腺とその周辺組織を示した説明図である。It is explanatory drawing which showed the prostate and its surrounding tissue. 前立腺が肥大した状態を示す説明図である。It is explanatory drawing which shows the state which the prostate enlarged. 前立腺モデルの構成を示した図であり、(a)は平面図、(b)は側面図、(c)は図7(a)のA-A矢視断面図である。It is the figure which showed the structure of the prostate model, (a) is a top view, (b) is a side view, (c) is AA arrow sectional drawing of Fig.7 (a). 前立腺部品の変形例を示した断面図である。It is sectional drawing which showed the modification of the prostate component. (a)~(d)は本発明の前立腺手術シミュレーターを用いたトレーニング方法を説明する工程図である。(a)-(d) is process drawing explaining the training method using the prostate surgery simulator of this invention.
 以下、図面に示した実施の形態に基づいて本発明を詳細に説明する。
1.前立腺手術シミュレーター
 図1は本発明の前立腺手術シミュレーター(以下、シミュレーターと略称する)の全体構成を示す斜視図である。
 同図において、シミュレーター1は、箱形のケース2と、そのケース2上に設置されているシミュレーター本体3とから構成されている。
 シミュレーター本体3は、下腹部を輪切りにしたような形状をなしており、例えばポリエステル樹脂をグラスファイバーで繊維補強したもので成形されている。
 シミュレーター本体3の前部には、尿道およびその周辺組織を模したシリコンゴム製の尿道部品4が嵌め込まれている。この尿道部品4には内視鏡挿入口4aを有する筒状の尿道部4b(図2参照)が設けられている。
 なお、図1においてX-X′は前後方向、Y-Y′は左右方向、Z-Z′は上下方向を示しており、前側は尿道側に、後側は膀胱側に対応している。
Hereinafter, the present invention will be described in detail based on the embodiments shown in the drawings.
1. Prostate Surgery Simulator FIG. 1 is a perspective view showing the overall configuration of a prostate surgery simulator (hereinafter abbreviated as a simulator) of the present invention.
In the figure, a simulator 1 is composed of a box-shaped case 2 and a simulator main body 3 installed on the case 2.
The simulator body 3 has a shape that is obtained by cutting the lower abdomen. The simulator body 3 is formed of, for example, a polyester resin fiber reinforced with glass fiber.
A urethra part 4 made of silicon rubber that imitates the urethra and its surrounding tissue is fitted in the front part of the simulator body 3. The urethral component 4 is provided with a cylindrical urethra portion 4b (see FIG. 2) having an endoscope insertion port 4a.
In FIG. 1, XX ′ indicates the front-rear direction, YY ′ indicates the left-right direction, and ZZ ′ indicates the up-down direction. The front side corresponds to the urethra side and the rear side corresponds to the bladder side.
 シミュレーター本体3の上部には開口部3aが設けられおり、この開口部3aを通して、後述する前立腺カートリッジの装着または取り外しが行えるようになっている。また、シミュレーター本体3内には膀胱を模した膀胱部品5(図2参照)が配置されている。
 なお、ケース2の底面にはシミュレーター1の移動を容易にするためのキャスター6が設けられている。
An opening 3a is provided in the upper part of the simulator body 3, and a prostate cartridge described later can be mounted or removed through this opening 3a. A bladder part 5 (see FIG. 2) simulating a bladder is disposed in the simulator body 3.
A caster 6 for facilitating the movement of the simulator 1 is provided on the bottom surface of the case 2.
 図2は上記シミュレーターの内部構成を示す断面図である。
 膀胱部品5は貯液部として機能するように容器状をなしており、この膀胱部品5には前立腺カートリッジを装着した状態で、還流水Wを貯液として蓄えるようになっている。
 膀胱部品5の外側にはその膀胱部品5を受け入れる容器5aが設けられており、容器5aの後部に設けられた排水口5bは、取水パイプ7を介して還流装置9の取水口9aと接続されている。上記還流水Wは、水または生理食塩水等の電解液が含まれる。
 還流装置9は、シミュレーションに使用した還流水Wを濾過するフィルターと濾過した還流水Wを吐出口9bから膀胱部品5へ送るポンプとを備えている。
 詳しくは、膀胱部品5をオーバーフローした還流水Wは、排水口5bから取水パイプ7を通じて還流装置9に取り込まれ、フィルターによって濾過され、濾過された還流水Wは2本に分岐された送水パイプ8a、8bにそれぞれ送られる。
FIG. 2 is a cross-sectional view showing the internal configuration of the simulator.
The bladder part 5 is formed in a container shape so as to function as a liquid storage part. The bladder part 5 stores the reflux water W as a liquid storage with a prostate cartridge attached.
A container 5 a for receiving the bladder part 5 is provided outside the bladder part 5, and a drain port 5 b provided at the rear part of the container 5 a is connected to the intake port 9 a of the reflux device 9 via the intake pipe 7. ing. The reflux water W includes an electrolytic solution such as water or physiological saline.
The reflux device 9 includes a filter for filtering the reflux water W used in the simulation and a pump for sending the filtered reflux water W to the bladder component 5 from the discharge port 9b.
Specifically, the reflux water W overflowing the bladder part 5 is taken into the reflux device 9 from the drain port 5b through the intake pipe 7 and filtered by the filter, and the filtered reflux water W is branched into two. , 8b, respectively.
 一方の送水パイプ8aは還流装置9の吐出口9bと前立腺カートリッジ10の前側空室10aとを連通しており、前立腺カートリッジ10における尿道部4bとの隙間を通じて還流水Wを膀胱部品5内に戻すようになっている。
 他方の送水パイプ8bは、上記吐出口9bと内視鏡30を収納している外筒器具14とを接続しており、送水パイプ8bから吐出された還流水Wは、外筒器具14内壁と内視鏡30との隙間を流れるようになっている。
 なお、外筒器具14に送られ内視鏡30のまわりから筒状に吐出される還流水Wは、内視鏡30の視野を拡げるためのものである。
One water supply pipe 8 a communicates the discharge port 9 b of the reflux device 9 and the front empty chamber 10 a of the prostate cartridge 10, and returns the reflux water W into the bladder part 5 through a gap between the urethra portion 4 b of the prostate cartridge 10. It is like that.
The other water supply pipe 8b connects the discharge port 9b and the outer cylinder device 14 housing the endoscope 30, and the reflux water W discharged from the water supply pipe 8b is connected to the inner wall of the outer cylinder device 14 with the inner wall. It flows through the gap with the endoscope 30.
The reflux water W that is sent to the outer cylinder device 14 and discharged in a cylindrical shape from around the endoscope 30 is for expanding the field of view of the endoscope 30.
 また、シミュレーター本体3の前部には水受け部2aが設けられており、尿道部品4から漏れ出た還流水Wを受け止め、排水パイプ2bを通じて排水タンク9cに導くようになっている。
 上記膀胱部品5の前部には前立腺カートリッジ10を嵌合することができる空洞部(凹部)5cが形成されており、その空洞部5cに前立腺カートリッジ10を装着すると、上記した尿道部品4の尿道部4bが、前立腺カートリッジ10の前側貫通孔10bに挿通されるようになっている。
 なお、図中5dは前立腺カートリッジ10を空洞部5cに保持するためのストッパーであり、矢印B方向に持ち上げると、前立腺カートリッジ10を取り外すことができるようになっている。
A water receiver 2a is provided at the front part of the simulator body 3, and receives the reflux water W leaked from the urethral component 4, and guides it to the drain tank 9c through the drain pipe 2b.
A cavity (recess) 5c into which the prostate cartridge 10 can be fitted is formed in the front part of the bladder part 5. When the prostate cartridge 10 is mounted in the cavity 5c, the urethra of the urethra part 4 described above. The portion 4b is inserted into the front through hole 10b of the prostate cartridge 10.
In the figure, reference numeral 5d denotes a stopper for holding the prostate cartridge 10 in the cavity 5c. When the prostate cartridge 10 is lifted in the direction of arrow B, the prostate cartridge 10 can be removed.
 図3はシミュレーター本体3を後方から見た説明図であり、前立腺カートリッジ10が装着された状態を示している。 FIG. 3 is an explanatory view of the simulator body 3 as viewed from the rear, and shows a state where the prostate cartridge 10 is mounted.
 図4は前立腺カートリッジ10を空洞部5cから取り外した状態を示しており、空洞部5cの奥側に、尿道部品4の尿道部4bが現われている。
 次に前立腺カートリッジ10の構成について説明するが、その前に前立腺肥大について説明する。
FIG. 4 shows a state in which the prostate cartridge 10 is removed from the cavity 5c, and the urethra 4b of the urethral component 4 appears on the back side of the cavity 5c.
Next, the configuration of the prostate cartridge 10 will be described. Before that, enlargement of the prostate will be described.
 図5は前立腺とその周辺組織を示したものである。
 前立腺20は膀胱21の出口付近に尿道22を取り巻くようにして存在しており、クルミの実程度の大きさからなり2層構造になっている。その内側部分を内腺20a、外側部分を外腺膜20bと呼び、正常な状態では内腺と外腺膜の厚さはほぼ同じである。なお、図中、23は精嚢、24は尿道括約筋である。
 前立腺が肥大すると、図6に示すように、内腺20aが膨張して腺腫となる一方で外腺膜20bは拡張され、あたかもミカンの中身(内腺20a)と皮(外腺膜20b)のような形状になる。
 前立腺肥大症になると、内腺20aが肥大して尿道22を圧迫し排尿困難や頻尿を引き起こすため、手術による治療においてその内腺20a部分を除去することになる。
FIG. 5 shows the prostate and surrounding tissues.
The prostate 20 exists so as to surround the urethra 22 in the vicinity of the outlet of the bladder 21, and has a two-layer structure having the size of a walnut. The inner portion is called the inner gland 20a and the outer portion is called the outer gland membrane 20b. Under normal conditions, the inner gland and the outer gland membrane have almost the same thickness. In the figure, 23 is a seminal vesicle and 24 is a urethral sphincter.
When the prostate enlarges, as shown in FIG. 6, the inner gland 20a expands to become an adenoma, while the outer gland membrane 20b expands, as if the contents of the mandarin orange (inner gland 20a) and the skin (outer gland membrane 20b). It becomes a shape like this.
When prostatic hypertrophy occurs, the inner gland 20a enlarges and presses the urethra 22 to cause difficulty in urination and frequent urination, so that the inner gland 20a portion is removed in the treatment by surgery.
2.前立腺カートリッジ
 図7は前立腺カートリッジの構成を示したものであり、同図(a)は平面図、(b)は側面図、(c)は図7(a)のA-A矢視断面図である。
 前立腺カートリッジ10は、カートリッジ外枠11と、そのカートリッジ外枠11内に収容され、肥大前立腺を模した前立腺部品12とから構成されており、前立腺カートリッジ10は、シミュレーションを実施する毎に、取り替えるようになっている。
2. Prostate Cartridge FIG. 7 shows the structure of the prostate cartridge. FIG. 7A is a plan view, FIG. 7B is a side view, and FIG. 7C is a cross-sectional view taken along the line AA in FIG. is there.
The prostate cartridge 10 is composed of a cartridge outer frame 11 and a prostate part 12 which is accommodated in the cartridge outer frame 11 and imitates an enlarged prostate. The prostate cartridge 10 is replaced every time a simulation is performed. It has become.
2.1 カートリッジ外枠
 カートリッジ外枠11は、ゼラチン、シリコンゴム、ウレンタン樹脂などの材料を有底筒状に成形した弾性体からなり、その前部には尿道部品4の尿道部4bが挿入される前側貫通孔10bが設けられている。
2.1 Cartridge outer frame The cartridge outer frame 11 is made of an elastic body formed of a material such as gelatin, silicone rubber, or urethane resin in a bottomed cylindrical shape, and the urethra portion 4b of the urethral component 4 is inserted into the front portion thereof. The front through-hole 10b is provided.
2.2 前立腺部品
 前立腺部品12は内腺部品と外腺膜部とからなり、内腺部品は肥大した右葉を模した右葉部品12a、肥大した左葉を模した左葉部品12b、中葉を模した中葉部品12cの三つの部分から構成されている。また、右葉部品12aと左葉部品12bの間には狭窄通路(尿管狭窄部)Uが意図的に形成されている。
 右葉部品12aの右側壁12dは、粘膜を模した粘着層12eを介して外腺膜部12fと接続されている。
 左葉部品12bの左側壁12gは、上記粘着層12eを介して外腺膜部12hと接続されている。
 右葉部品12aおよび左葉部品12bの下方(図7(a)では右側)に配置されている中葉部品12cは、粘着層12e′を介して外腺膜部12f、12hと接続されるとともに、右葉部品12aおよび左葉部品12bとも接続されている。
2.2 Prostate parts The prostate part 12 is composed of an inner gland part and an outer gland membrane part, and the inner gland parts are a right lobe part 12a imitating an enlarged right lobe, a left lobe part 12b imitating an enlarged left lobe, and a middle lobe. It is comprised from three parts of the middle leaf part 12c which imitated. A stenosis passage (ureter stenosis) U is intentionally formed between the right lobe component 12a and the left lobe component 12b.
The right side wall 12d of the right lobe component 12a is connected to the outer gland membrane portion 12f via an adhesive layer 12e simulating mucous membranes.
The left side wall 12g of the left lobe component 12b is connected to the outer gland membrane portion 12h via the adhesive layer 12e.
The middle lobe component 12c disposed below the right lobe component 12a and the left lobe component 12b (on the right side in FIG. 7 (a)) is connected to the outer gland membrane portions 12f and 12h via the adhesive layer 12e ′, The right lobe component 12a and the left lobe component 12b are also connected.
 上記構成からなる前立腺部品12は、カートリッジ外枠11内で狭窄通路Uを取り囲むようにして組み立てられるようになっている。そして、上記膀胱部品5の空洞部5c内に装着された後、膀胱部品5に貯溜された還流水Wによって浸漬されるようになっている。
 上記右葉部品12a、左葉部品12b、中葉部品12cは、小麦を主原料にした粉末状の真空乾燥グルテン40~70質量部、澱粉0~20質量部、グリセリン30~50質量部および水5質量部を混ぜ合わせたものを、100~120℃で60~90分間加熱することによって塊状に成形している。なお、グリセリンは、内腺部品の硬さを柔らかくするための調整剤として使用している。
 上記外腺膜部12f,12hは、粉状の真空乾燥グルテン35~65質量部、澱粉0~35質量部、グリセリン40~60質量部および水5~10質量部を混ぜ合わせたものを、110℃で75分間加熱することにより袋状に成形している。
The prostate part 12 having the above-described configuration is assembled so as to surround the narrowed passage U in the cartridge outer frame 11. Then, after being mounted in the cavity 5 c of the bladder part 5, it is immersed in the reflux water W stored in the bladder part 5.
The right leaf part 12a, the left leaf part 12b, and the middle leaf part 12c are 40 to 70 parts by mass of powdered vacuum-dried gluten containing wheat as a main raw material, 0 to 20 parts by mass of starch, 30 to 50 parts by mass of glycerin, and water 5 A mixture of parts by mass is formed into a lump by heating at 100 to 120 ° C. for 60 to 90 minutes. Glycerin is used as an adjuster for softening the hardness of the inner gland component.
The outer gland membrane portions 12f and 12h are prepared by mixing powdery vacuum-dried gluten 35 to 65 parts by mass, starch 0 to 35 parts by mass, glycerin 40 to 60 parts by mass and water 5 to 10 parts by mass. It is formed into a bag shape by heating at 75 ° C. for 75 minutes.
 内腺部品および外腺膜部12f、12hの硬さは、グルテンの含有量に比例するため、例えば、初心者がシミュレーションする場合には、グルテンの配合量を少なくして柔らかくし、熟練者がシミュレーションする場合には、グルテンの配合量を多くして硬くするなど、トレーニング者の技量に応じて調節することができる。
 また、上記粘着層12eは、粉末状の真空乾燥グルテンとグリセリンとを混ぜ合わせることにより得ることができる。グルテンのみでは固化してしまい弾性が失われるため、グリセリンを加えることにより弾性(粘り)が維持されるようにしている。
Since the hardness of the inner gland parts and outer gland membrane portions 12f and 12h is proportional to the gluten content, for example, when a beginner performs a simulation, the gluten content is reduced to make it softer, and an expert performs the simulation. When doing so, it can be adjusted according to the skill of the trainee, such as increasing the blending amount of gluten to make it harder.
The pressure-sensitive adhesive layer 12e can be obtained by mixing powdery vacuum-dried gluten and glycerin. Since gluten only solidifies and loses elasticity, the elasticity (stickiness) is maintained by adding glycerin.
 グルテンとグリセリンとの合計量に対し、グリセリンの存在量は0.7~1.4倍の範囲で選択することができ、0.9~1.1倍が好ましく、1.0倍が最も好ましい。グルテンとグリセリンの配合比が1.0:1.0のもの、具体的には真空乾燥グルテン50質量部とグリセリン50質量部を混ぜ合わせたものは、最も生体に近いとの結果が得られている。
 グリセリンの存在量が1.0倍を超えて1.4倍以下である場合には出力の弱いレーザーでも簡単に切除できる。したがって、この配合比は、対象部位とレーザー照射部との距離感覚に慣れていない施術者向けとすることができる。
The amount of glycerol present can be selected in the range of 0.7 to 1.4 times the total amount of gluten and glycerol, preferably 0.9 to 1.1 times, and most preferably 1.0 times. . The result that the mixture ratio of gluten and glycerin is 1.0: 1.0, specifically, the mixture of 50 parts by mass of vacuum-dried gluten and 50 parts by mass of glycerin is the closest to the living body. Yes.
When the amount of glycerin is more than 1.0 times and 1.4 times or less, it can be easily excised with a laser having a weak output. Therefore, this blending ratio can be used for a practitioner who is not accustomed to the sense of distance between the target site and the laser irradiation unit.
 また、グリセリンの存在量が0.7倍以上1.0倍未満であると、粘りが強く、レーザーの出力を上げて照射距離を短く且つ一定に保持する技術が必要となり、注意を払わないと外腺部まで切除する虞がある。したがって、この配合比のものは、上級者向けとすることができる。
 さらにまた、グリセリンの存在量が0.7倍未満と少なすぎる場合には、レーザーで切除するのに要する時間が長くなり実際の人体における手術感覚と異なってしまうという不都合があり、1.4倍を超えて多すぎる場合には、レーザーを照射した瞬間に崩れてしまうために採用することができない。
 また、グルテン、グリセリン以外に例えば澱粉を使用すると、レーザー照射時に濁りが発生して視界が悪くなるため、粘着層12eについてはグルテンとグリセリンのみを使用した。
Also, if the amount of glycerin is 0.7 times or more and less than 1.0 times, the stickiness is strong, and it is necessary to have a technique for increasing the output of the laser to keep the irradiation distance short and constant. There is a risk of removing the outer gland. Therefore, those with this blending ratio can be intended for advanced users.
Furthermore, if the amount of glycerin is too small, less than 0.7 times, the time required for excision with the laser becomes long, which is inconvenient that it differs from the actual surgical sensation in the human body, 1.4 times. If the amount is too much, it cannot be used because it collapses at the moment of laser irradiation.
Further, when starch is used in addition to gluten and glycerin, for example, turbidity is generated during laser irradiation and visibility is deteriorated. Therefore, only gluten and glycerin are used for the adhesive layer 12e.
 なお、本実施形態で使用するグルテンは、上記した小麦または大豆を主原料としたグルテンを使用することが好ましく、ホルミウムヤグレーザーを当てても焦げることがないように糖分を含まないものが推奨される。
 また、粘着層12eを形成するにあたっては、上記配合によって得られた粘着材料を膜状に塗布することにより形成することができ、また、筋状に塗布することによって形成することもでき、さらにまた、予めシート状または網状に形成したものを貼り付けることによって形成することもできる。
The gluten used in the present embodiment is preferably gluten mainly composed of wheat or soybean as described above, and one that does not contain sugar is recommended so that it does not burn even when holmium yag laser is applied. The
In forming the pressure-sensitive adhesive layer 12e, the pressure-sensitive adhesive material obtained by the above blending can be formed in a film shape, and can also be formed by applying it in a streak shape. Alternatively, it may be formed by pasting a sheet or net formed in advance.
 前立腺部品の材料と配合比を特定するにあたっては、以下に示すように、様々な材料について試験を行った。例えば、
 材料aとして、ゼラチン粉末と水と樹脂繊維を混合し固めたものは、レーザーを照射した際に、樹脂繊維が溶ける前に周りのゼラチンが溶けてしまい、樹脂繊維が飛び出てしまうというという結果となった。
 材料bとして、上記材質aにさらにグリセリン、粒状ゴムを加えても溶けすぎるという点は改善できなかった。
 材料cとして、ゼラチン粉末と水とグリセリンを混合し固めたものは、熱によって周囲まで溶かし過ぎるという結果になった。
 材料dとして、ささみを使用したものは、ほぼリアルな感触が得られたものの形状が若干、盛り上がり、凝固してしまうという結果になった。動物系の材料は白濁しやすいため、植物由来の材料の方が好ましいと分かった。
 材料eとして、シリコン樹脂系のものはレーザー照射時に焦げるという問題があり、シリコン樹脂の燃焼温度が高いことによりレーザー照射部分のみが赤く発光することから除外となった。
 上記した以外にも各種材料について試験を行ったが、グルテンとグリセリンを基本とし、水を加えたものが最もリアルな感触の得られることが確認された。
In identifying the prostate component materials and blending ratios, various materials were tested as shown below. For example,
As the material a, gelatin powder, water and resin fibers mixed and hardened, when irradiated with laser, the surrounding gelatin melts before the resin fibers melt, and the resin fibers pop out. became.
Even if glycerin or granular rubber was further added to the material a as the material b, it was not possible to improve it.
As the material c, a mixture of gelatin powder, water and glycerin mixed and hardened resulted in excessive dissolution to the surroundings by heat.
The material d using scissors as the material d resulted in a slightly swelled and solidified shape that provided an almost realistic feel. It has been found that plant-based materials are preferable because animal-based materials tend to become cloudy.
As the material e, a silicon resin-based material has a problem that it is burnt during laser irradiation, and is excluded because only the laser irradiated portion emits red light due to the high combustion temperature of the silicon resin.
In addition to the above, various materials were tested, and it was confirmed that the most realistic feel was obtained when water was added based on gluten and glycerin.
 また、粘着層12eについては、ホルミウムヤグレーザーによって切断した跡がその他の粘着層と明瞭に識別できるものが好ましい。
 HoLEP手術のトレーニングを行う術者は、ホルミウムヤグレーザーを用いて粘着層12eを特定の方向に焼き切ることにより、例えば右葉部品12aを外腺膜部12fから徐々に剥がしていく感覚を体験することができる。
 そこで、内腺部品と外腺膜部12fにそれぞれ異なる色で着色を施しておけば、それぞれの部位を判別しやすくなる。
 また、内腺部品、外腺膜部12f,12hについて硬さの異なる部品を複数種類用意することにより、初心者から熟練者まで幅広く核出手術をシミュレーションすることが可能になる。
Moreover, about the adhesion layer 12e, what can distinguish the trace cut | disconnected with the holmium yag laser clearly from other adhesion layers is preferable.
An operator who performs HoLEP surgery training experiences a sensation of gradually peeling off the right lobe component 12a from the outer gland membrane portion 12f, for example, by burning out the adhesive layer 12e in a specific direction using a holmium yag laser. Can do.
Therefore, if the inner gland component and the outer gland membrane portion 12f are colored with different colors, it becomes easy to distinguish each part.
In addition, by preparing a plurality of types of parts having different hardnesses for the inner gland parts and the outer gland membrane parts 12f and 12h, it becomes possible to simulate a nuclear surgery from a beginner to an expert.
 図8は前立腺部品の変形例を示した断面図であり、図7(c)に対応している。
 同図に示す前立腺部品13は、右葉部品13aと外腺膜部13bとの間に隙間Sを設けており、その隙間Sに、右葉部品13aと外腺膜部13bとを部分的に接続する粘着シート13cを厚さ2~6mm積層している。
 粘着シート13cは、すべて同じ材料(グルテン+グリセリン)から構成されており、柔らかいゴムのような弾性と粘着性を有している。したがって、矢印F方向に押せば厚み方向に変形することができるようになっている。これは、実際の施術の際と同様に、内視鏡に押されて前後方向(尿道部品4-膀胱部品5方向)に動かせることができるようにとの要望に答えたものである。
FIG. 8 is a cross-sectional view showing a modified example of the prostate part, and corresponds to FIG.
The prostate component 13 shown in the figure has a gap S between the right lobe component 13a and the outer gland membrane portion 13b, and the right lobe component 13a and the outer gland membrane portion 13b are partially separated in the gap S. The adhesive sheet 13c to be connected is laminated with a thickness of 2 to 6 mm.
The adhesive sheets 13c are all made of the same material (gluten + glycerin) and have elasticity and adhesiveness like soft rubber. Therefore, if it is pushed in the direction of arrow F, it can be deformed in the thickness direction. This is in response to the request that it can be moved forward and backward (in the direction of the urethra component 4-blade component 5) by being pushed by the endoscope, as in the case of actual treatment.
 それにより、実際の手術技に近い状態で例えば右葉部品13aを外腺膜部13bから剥がしていくという感覚を体験することができる。
 なお、左葉部品13dについても同様に隙間Sを設け、同様に粘着シート13cを介して左葉部品13dと外腺膜部13bとを接続する。
 また、本発明において、外腺膜部と前立腺部品とを接続している部分、あるいはその接続部分の周辺に、血管組織の代わりとして細いチューブを這わせ、赤い液体をそのチューブに流せば、ホルミウムヤグレーザーを用いた止血も体験することが可能になる。
Thereby, it is possible to experience a feeling of peeling off the right lobe component 13a from the outer gland membrane portion 13b, for example, in a state close to the actual surgical technique.
The left lobe component 13d is similarly provided with a gap S, and similarly, the left lobe component 13d and the outer gland membrane portion 13b are connected via the adhesive sheet 13c.
Further, in the present invention, if a thin tube is placed instead of the vascular tissue around the connecting part of the outer gland membrane part and the prostate part, or around the connecting part, and a red liquid is poured into the tube, holmium It will also be possible to experience hemostasis using a yag laser.
 次に、本発明のシミュレーターを用いた前立腺治療手術のトレーニング方法について図9の工程図を参照しながら説明する。
 図9(a)において、尿道部品4の内視鏡挿入口4a(図2参照)からHoLEP用の内視鏡30を挿入し、さらに狭窄通路Uを通じてその内視鏡30を膀胱部品5内に挿入する。
 挿入した内視鏡30によって右葉部品13a、左葉部品13b、中葉部品12c(図7(a)参照)、膀胱部品5を観察する。
 前立腺の内腺は、右葉と左葉と中葉とから構成されており、核出トレーニングを行うにあたり、まず、中葉を模した中葉部品の核出を行う。
Next, a training method for prostate treatment surgery using the simulator of the present invention will be described with reference to the process diagram of FIG.
9A, the HoLEP endoscope 30 is inserted from the endoscope insertion port 4a (see FIG. 2) of the urethral component 4, and the endoscope 30 is inserted into the bladder component 5 through the narrowed passage U. insert.
The right lobe component 13a, the left lobe component 13b, the middle lobe component 12c (see FIG. 7A), and the bladder component 5 are observed with the inserted endoscope 30.
The internal gland of the prostate is composed of a right lobe, a left lobe, and a middle lobe. When performing enucleation training, first, the middle lobe part imitating the middle lobe is enucleated.
 精嚢の横で粘着層12e′(図7(a)参照)をホルミウムヤグレーザーによって切開し、中葉部品12cと外腺膜部12f,12hとの間の境界層を見つける。
 ホルミウムヤグレーザーは水、または生理食塩水等の電解液への吸収率が高く、2.0mm以下の距離では組織の切除が可能になり同時に組織を焼くことで止血が行われ、また、レーザーファイバーの先端を組織から5.0mm離すと組織に影響を与えない。
Next to the seminal vesicle, the adhesive layer 12e ′ (see FIG. 7A) is incised by a holmium yag laser to find a boundary layer between the middle lobe component 12c and the outer gland membrane portions 12f and 12h.
The holmium yag laser has a high absorption rate in water or saline and other electrolytes, and the tissue can be excised at a distance of 2.0 mm or less, and at the same time, hemostasis is performed by burning the tissue. If the tip of the tube is separated from the tissue by 5.0 mm, the tissue is not affected.
 本発明の前立腺部品12では、ホルミウムヤグレーザーによって切除する粘膜を模した粘着層12e,12e′を備えているため、それらの粘膜層12e,12e′に対してホルミウムヤグレーザーのレーザーファイバー先端を近づけ、赤く照らされた部分を目標にして切除作業を行うことにより、実際の手術における核出とほぼ同じような核出手術を体験することができる。
 グルテンとグリセリンから構成された粘着層12eに対し、ホルミウムヤグレーザーを至近距離から照射すると、粘着層12eの網構造が切断されて綿くず状に変化していく。この様子は実際に内腺と外腺膜との間の粘膜をレーザーによって切断した状態と酷似しており、内腺を剥離するときの感覚を体験することができる。
Since the prostate component 12 of the present invention includes the adhesive layers 12e and 12e 'imitating the mucous membrane to be excised by the holmium yag laser, the laser fiber tip of the holmium yag laser is brought close to the mucosal layers 12e and 12e'. By performing the excision work with the red illuminated part as a target, it is possible to experience a nuclear operation that is almost the same as the actual operation.
When the holmium yag laser is irradiated from a close distance to the adhesive layer 12e composed of gluten and glycerin, the network structure of the adhesive layer 12e is cut and changed into a lint-like shape. This situation is very similar to the state in which the mucous membrane between the inner gland and the outer gland membrane is cut with a laser, and you can experience the sensation of peeling the inner gland.
 次いで、上記粘着層12e′に沿って中葉部品12cの背面側に入り、中葉部品12cをめくり上げるように膀胱部品5側に向かって剥離していく。
 次いで、膀胱部品5における膀胱頸部に相当する部分から中葉部品12cの両側について粘着層12e′を切開する。
 このとき、中葉部品12cは膀胱頸部に相当する部分のみで付着している状態になるため、この付着部分を切離し、中葉部品12cを膀胱部品5内に遊離させる。それにより、中葉部品12cの核出トレーニングが完了する。
Next, it enters the back side of the middle lobe component 12c along the adhesive layer 12e 'and peels toward the bladder component 5 so as to turn up the middle lobe component 12c.
Next, the adhesive layer 12e ′ is cut out on both sides of the middle lobe component 12c from the portion corresponding to the bladder neck of the bladder component 5.
At this time, since the middle lobe component 12c is attached only at the portion corresponding to the bladder neck, the attached portion is cut off to release the middle lobe component 12c into the bladder component 5. Thereby, the core training of the middle leaf part 12c is completed.
 次に、右葉部品12aの核出トレーニングを行う。なお、左葉部品12bから核出トレーニングを行なってもよい。
 図9(b)において、右葉部品12aと外腺膜部12fとの境界層、すなわち粘着層12eにホルミウムヤグレーザー31を照射することにより、右葉部品12aを外腺膜部12fから剥離していく。このとき、括約筋がある尿道側から膀胱部品5側、および腹側に向かって剥離を行う。なお、膀胱部品5は図示を省略している。
 尿道側で、腹側から背側へ、あるいは背側から腹側に向かって、右葉部品12aの輪郭に沿って、粘着層12eを剥離していき剥離部分を連続させる。
 次いで、腹側から背側につながった、外腺膜12fと右葉部品12aとの間の粘着層12eを、尿道側から膀胱部品5に向かって腹側背側均等に剥離していく。この剥離が進むと、右葉部品12aはほとんど膀胱頸部のみで付着している状態となる(図9(c)参照)。
Next, enucleation training for the right lobe component 12a is performed. Note that enucleation training may be performed from the left lobe component 12b.
In FIG. 9B, the right lobe component 12a is detached from the outer gland membrane portion 12f by irradiating the boundary layer between the right lobe component 12a and the outer gland membrane portion 12f, that is, the adhesive layer 12e, with the holmium yag laser 31. To go. At this time, peeling is performed from the urethra side where the sphincter is located toward the bladder part 5 side and the abdomen side. The bladder part 5 is not shown.
On the urethra side, the adhesive layer 12e is peeled along the outline of the right lobe component 12a from the ventral side to the dorsal side or from the dorsal side to the ventral side, and the peeled portion is made continuous.
Next, the adhesive layer 12e between the outer gland membrane 12f and the right lobe component 12a connected from the ventral side to the dorsal side is evenly peeled from the urethra side toward the bladder component 5 on the ventral dorsal side. As this separation progresses, the right lobe component 12a is attached only at the bladder neck (see FIG. 9C).
 図9(d)において、膀胱頸部につながっている部分を切り離し、右葉部品12aを遊離させ、右葉部品12aの核出トレーニングを終了する。
 左葉部品12bの核出トレーニングも上記右葉部品12aの核出トレーニングと同様の方法で行い、それにより、内腺の核出トレーニングが完了する。
 前側貫通孔10bから腎盂鏡(ストルツ)を挿入し、モルセレーターを用いて、膀胱部品5内に核出された腺の細切と回収を行う。
 次いで、前側貫通孔10bから20Fr程度の尿道カテーテルを留置してトレーニングが終了する。
In FIG.9 (d), the part connected to the bladder neck part is cut off, the right lobe part 12a is released, and the enucleation training of the right lobe part 12a is completed.
Enucleation training for the left lobe component 12b is also performed in the same manner as the enucleation training for the right lobe component 12a, thereby completing the enucleation training for the inner gland.
A nephroscope (Struts) is inserted from the front through-hole 10b, and the glandularized nucleus in the bladder part 5 is cut and collected using a molcerator.
Next, the urinary catheter of about 20 Fr is placed from the front through-hole 10b to complete the training.
 本願は、2011年11月17日に出願された日本国特許出願第2011-251695号に基づく優先権の利益を主張するものである。2011年11月17日に出願された日本国特許出願第2011-251695号の明細書の全内容が、本願に参考のため援用される。 This application claims the benefit of priority based on Japanese Patent Application No. 2011-251695 filed on November 17, 2011. The entire contents of the specification of Japanese Patent Application No. 2011-251695 filed on November 17, 2011 are incorporated herein by reference.
 本発明の前立腺肥大モデルおよび前立腺手術シミュレーターは、前立腺肥大症を治療する手術手技を習得するための手段として利用することができる。 The prostatic hypertrophy model and the prostatic surgery simulator of the present invention can be used as a means for acquiring a surgical technique for treating prostatic hypertrophy.
 1  シミュレーター
 2  ケース
 3  シミュレーター本体
 3a 開口部
 4  尿道部品
 4a 内視鏡挿入口
 5  膀胱部品
 6  キャスター
 7  取水パイプ
 8a,8b 送水パイプ
 9  還流装置
10  前立腺カートリッジ
11  カートリッジ外枠
12  前立腺部品
12a 右葉部品
12b 左葉部品
12c 中葉部品
12d 右側壁
12e 粘着層
12e′ 粘着層
12f 外腺膜部
12g 左側壁
12h 外腺膜部
14  外筒器具
30  内視鏡
31  ホルミウムヤグレーザー
 U  狭窄通路(尿管狭窄部)
 W  還流水
DESCRIPTION OF SYMBOLS 1 Simulator 2 Case 3 Simulator main body 3a Opening part 4 Urethral part 4a Endoscope insertion port 5 Bladder part 6 Caster 7 Water intake pipe 8a, 8b Water supply pipe 9 Reflux device 10 Prostate cartridge 11 Cartridge outer frame 12 Prostate part 12a Right lobe part 12b Left lobe component 12c Middle lobe component 12d Right side wall 12e Adhesive layer 12e 'Adhesive layer 12f Outer gland membrane part 12g Left side wall 12h Outer gland membrane part 14 Outer tube instrument 30 Endoscope 31 Holmium yag laser U Stenosis passage (ureter stenosis)
W Reflux water

Claims (8)

  1.  前立腺における肥大した内腺を模した内腺部品と、外腺膜を模した外腺膜部とを有し、
     上記外腺膜部は上記内腺部品の外周面を被覆しており、
     上記内腺部品内に尿管狭窄部が形成されており、
     上記内腺部品と上記外腺膜部とが粘着層によって接続され、その粘着層が、グルテンとグリセリンとの混合物から構成されていることを特徴とする前立腺肥大モデル。
    It has an inner gland part that imitates the enlarged gland in the prostate, and an outer gland membrane part that mimics the outer gland membrane,
    The outer gland membrane part covers the outer peripheral surface of the inner gland component,
    A ureteral stricture is formed in the inner gland component,
    A prostatic hypertrophy model, wherein the inner gland component and the outer gland membrane part are connected by an adhesive layer, and the adhesive layer is composed of a mixture of gluten and glycerin.
  2.  上記内腺部品が、右葉を模した右葉部品と、左葉を模した左葉部品と、中葉を模した中葉部品とを組み合わせたものからなり、上記中葉部品がさらに上記粘着層を介して上記右葉部品と上記左葉部品とに跨がって接続されている請求項1に記載の前立腺肥大モデル。 The inner gland component is a combination of a right lobe component imitating the right lobe, a left lobe component imitating the left lobe, and a middle lobe component imitating the middle lobe, and the intermediate lobe component further passes through the adhesive layer. The prostatic hypertrophy model according to claim 1, wherein the prostatic hypertrophy model is connected across the right lobe component and the left lobe component.
  3.  上記粘着層における上記グルテンと上記グリセリンの合計量に対し、グリセリンの存在量が0.7~1.4倍である請求項1または2に記載の前立腺肥大モデル。 The prostatic hypertrophy model according to claim 1 or 2, wherein the amount of glycerin present is 0.7 to 1.4 times the total amount of gluten and glycerin in the adhesive layer.
  4.  上記内腺部品および上記外腺膜部が、グルテン、澱粉、グリセリン、水との混合物を加熱したものから構成されている請求項1または2に記載の前立腺肥大モデル。 The prostatic hypertrophy model according to claim 1 or 2, wherein the inner gland component and the outer gland membrane part are constituted by heating a mixture of gluten, starch, glycerin and water.
  5.  請求項1~4のいずれか1項に記載の前立腺肥大モデルと、
     上記前立腺肥大モデルを着脱し得る凹部と、上記尿管狭窄部と連通する貯液部とを有し膀胱を模した膀胱部品とから構成されていることを特徴とする前立腺手術シミュレーター。
    A prostatic hypertrophy model according to any one of claims 1 to 4,
    A prostate surgery simulator, comprising: a bladder part that can attach and detach the prostatic hypertrophy model; and a bladder part that simulates the bladder and has a liquid storage part that communicates with the ureteral stenosis part.
  6.  上記凹部に装着された上記前立腺肥大モデルの尿管狭窄部が、尿道を模した尿道部品と連通するように構成されている請求項5に記載の前立腺手術シミュレーター。 The prostate surgery simulator according to claim 5, wherein the ureteral stricture portion of the prostatic hypertrophy model mounted in the recess is configured to communicate with a urethral component simulating a urethra.
  7.  上記貯液部に水、または生理食塩水等の電解液が充填されている請求項5または6に記載の前立腺手術シミュレーター。 The prostate surgery simulator according to claim 5 or 6, wherein the liquid storage part is filled with an electrolyte such as water or physiological saline.
  8.  上記貯液部内の貯液を濾過し上記貯液部に還流させる還流装置が備えられている請求項5~7のいずれか1項に記載の前立腺手術シミュレーター。 The prostate surgery simulator according to any one of claims 5 to 7, further comprising a reflux device for filtering the liquid stored in the liquid storage part and refluxing the liquid storage part.
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