WO2013066734A1 - Process and intermediates for the preparation of 3-amino-4-cyclobutyl-2-hydroxybutanamide and salts thereof - Google Patents

Process and intermediates for the preparation of 3-amino-4-cyclobutyl-2-hydroxybutanamide and salts thereof Download PDF

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Publication number
WO2013066734A1
WO2013066734A1 PCT/US2012/062025 US2012062025W WO2013066734A1 WO 2013066734 A1 WO2013066734 A1 WO 2013066734A1 US 2012062025 W US2012062025 W US 2012062025W WO 2013066734 A1 WO2013066734 A1 WO 2013066734A1
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WO
WIPO (PCT)
Prior art keywords
group consisting
process
selected
acid
alkyl
Prior art date
Application number
PCT/US2012/062025
Other languages
French (fr)
Inventor
George G. Wu
Tetsuji Itoh
Mark Mclaughlin
Zhijian Liu
Gang Qian
Original Assignee
Merck Sharp & Dohme Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201161553370P priority Critical
Priority to US61/553,370 priority
Application filed by Merck Sharp & Dohme Corp. filed Critical Merck Sharp & Dohme Corp.
Publication of WO2013066734A1 publication Critical patent/WO2013066734A1/en

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