WO2013054126A3 - Nanocolloids for local temperature monitoring - Google Patents

Nanocolloids for local temperature monitoring Download PDF

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Publication number
WO2013054126A3
WO2013054126A3 PCT/GB2012/052530 GB2012052530W WO2013054126A3 WO 2013054126 A3 WO2013054126 A3 WO 2013054126A3 GB 2012052530 W GB2012052530 W GB 2012052530W WO 2013054126 A3 WO2013054126 A3 WO 2013054126A3
Authority
WO
WIPO (PCT)
Prior art keywords
shell
nanoparticle
nanocolloids
temperature monitoring
local temperature
Prior art date
Application number
PCT/GB2012/052530
Other languages
French (fr)
Other versions
WO2013054126A2 (en
Inventor
Michael P. Macdonald
Pascal Andre
Shu Chen
Original Assignee
University Court Of The University Of St Andrews
University Of Dundee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Court Of The University Of St Andrews, University Of Dundee filed Critical University Court Of The University Of St Andrews
Publication of WO2013054126A2 publication Critical patent/WO2013054126A2/en
Publication of WO2013054126A3 publication Critical patent/WO2013054126A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
    • A61N1/406—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia using implantable thermoseeds or injected particles for localized hyperthermia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/05—Metallic powder characterised by the size or surface area of the particles
    • B22F1/054—Nanosized particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/10—Metallic powder containing lubricating or binding agents; Metallic powder containing organic material
    • B22F1/102—Metallic powder coated with organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/16—Metallic particles coated with a non-metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C2202/00—Physical properties
    • C22C2202/02—Magnetic

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Power Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Composite Materials (AREA)
  • Luminescent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention provides a method of determining the temperature of a luminescent nanoparticle comprising causing the nanoparticle to luminesce and measuring the luminescence lifetime of luminescent moieties of the nanoparticle, wherein the nanoparticle has a core-shell architecture comprising a metal and/or magnetic nanoparticle-containing core, a first shell encapsulating the core and a second shell encapsulating the first shell, wherein the second shell comprises a plurality of luminescent moieties and the first shell comprises a lower concentration or amount of luminescent moieties than are comprised in the second shell.
PCT/GB2012/052530 2011-10-13 2012-10-12 Nanocolloids for local temperature monitoring WO2013054126A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1117675.7 2011-10-13
GBGB1117675.7A GB201117675D0 (en) 2011-10-13 2011-10-13 Nanocolloids for local temperature monitoring

Publications (2)

Publication Number Publication Date
WO2013054126A2 WO2013054126A2 (en) 2013-04-18
WO2013054126A3 true WO2013054126A3 (en) 2013-06-13

Family

ID=45091981

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2012/052530 WO2013054126A2 (en) 2011-10-13 2012-10-12 Nanocolloids for local temperature monitoring

Country Status (2)

Country Link
GB (1) GB201117675D0 (en)
WO (1) WO2013054126A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3286330B1 (en) * 2015-04-20 2019-04-17 ETH Zurich Particulate distributed sensing elements
CN114622050B (en) * 2020-12-14 2023-04-28 中冶长天国际工程有限责任公司 Method for accurately measuring and adjusting material temperature in air quantity control rotary kiln

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006064453A2 (en) * 2004-12-17 2006-06-22 Koninklijke Philips Electronics N.V. Targeting agents for molecular imaging
EP2210616A1 (en) * 2009-01-21 2010-07-28 Centre National de la Recherche Scientifique Multifunctional stealth nanoparticles for biomedical use
US7829140B1 (en) * 2006-03-29 2010-11-09 The Research Foundation Of The State University Of New York Method of forming iron oxide core metal shell nanoparticles
US20110031452A1 (en) * 2007-11-28 2011-02-10 Todd Krauss Nanoparticles Having Continuous Photoluminescence

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040101822A1 (en) 2002-11-26 2004-05-27 Ulrich Wiesner Fluorescent silica-based nanoparticles
AU2006288048A1 (en) 2005-09-08 2007-03-15 Biterials Co., Ltd. Magnetic nanoparticle having fluorescent and preparation method thereof and use thereof
US20120077279A1 (en) 2009-04-15 2012-03-29 Cornell University Silica Nanoparticles Incorporating Chemiluminescent And Absorbing Active Molecules
PL2449379T3 (en) 2009-07-02 2017-12-29 Sloan-Kettering Institute For Cancer Research Fluorescent silica-based nanoparticles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006064453A2 (en) * 2004-12-17 2006-06-22 Koninklijke Philips Electronics N.V. Targeting agents for molecular imaging
US7829140B1 (en) * 2006-03-29 2010-11-09 The Research Foundation Of The State University Of New York Method of forming iron oxide core metal shell nanoparticles
US20110031452A1 (en) * 2007-11-28 2011-02-10 Todd Krauss Nanoparticles Having Continuous Photoluminescence
EP2210616A1 (en) * 2009-01-21 2010-07-28 Centre National de la Recherche Scientifique Multifunctional stealth nanoparticles for biomedical use

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CARLOS D. S. BRITES ET AL: "A Luminescent Molecular Thermometer for Long-Term Absolute Temperature Measurements at the Nanoscale", ADVANCED MATERIALS, vol. 22, no. 40, 25 October 2010 (2010-10-25), pages 4499 - 4504, XP055051877, ISSN: 0935-9648, DOI: 10.1002/adma.201001780 *
HO CHANG, SHENG-HONG WU: "Hybridization of FePt/ZnS Nanocore-Shell Structurewith DNAs of Different Sequences", MATERIALS TRANSACTIONS, vol. 51, no. 11, 6 October 2010 (2010-10-06), The Japan Institute of Metals, pages 2094 - 2098, XP002691633, Retrieved from the Internet <URL:http://www.jim.or.jp/journal/e/pdf3/51/11/2094.pdf> [retrieved on 20130205] *
SHAOPENG WANG ET AL: "Nanoparticle Luminescence Thermometry", THE JOURNAL OF PHYSICAL CHEMISTRY B, vol. 106, no. 43, 1 October 2002 (2002-10-01), pages 11203 - 11209, XP055051172, ISSN: 1520-6106, DOI: 10.1021/jp026445m *
SHU CHEN ET AL: "A water-soluble temperature nanoprobe based on a multimodal magnetic-luminescent nanocolloid", CHEMICAL COMMUNICATIONS, vol. 48, no. 19, 1 March 2012 (2012-03-01), pages 2501 - 2503, XP055052412, ISSN: 1359-7345, DOI: 10.1039/c2cc17160k *
SHU CHEN ET AL: "Engineered Biocompatible Nanoparticles for in Vivo Imaging Applications", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132, no. 42, 27 October 2010 (2010-10-27), pages 15022 - 15029, XP055051690, ISSN: 0002-7863, DOI: 10.1021/ja106543j *
YOON TAE-JONG ET AL: "SPECIFIC TARGETING, CELL SORTING, AND BIOIMAGING WITH SMART MAGNETIC SILICA CORE-SHELL NANOMATERIALS", SMALL, WILEY - VCH VERLAG GMBH & CO. KGAA, DE, vol. 2, no. 2, 1 January 2006 (2006-01-01), pages 209 - 215, XP008079879, ISSN: 1613-6810, DOI: 10.1002/SMLL.200500360 *

Also Published As

Publication number Publication date
GB201117675D0 (en) 2011-11-23
WO2013054126A2 (en) 2013-04-18

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