WO2013053034A3 - Thiazacridines utilisées dans la thérapie anticancéreuse - Google Patents

Thiazacridines utilisées dans la thérapie anticancéreuse Download PDF

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Publication number
WO2013053034A3
WO2013053034A3 PCT/BR2012/000421 BR2012000421W WO2013053034A3 WO 2013053034 A3 WO2013053034 A3 WO 2013053034A3 BR 2012000421 W BR2012000421 W BR 2012000421W WO 2013053034 A3 WO2013053034 A3 WO 2013053034A3
Authority
WO
WIPO (PCT)
Prior art keywords
thiazacridines
cancer therapy
denominated
thiazolidine
acridinyl
Prior art date
Application number
PCT/BR2012/000421
Other languages
English (en)
Portuguese (pt)
Other versions
WO2013053034A2 (fr
Inventor
GALDINO. Suely LINS
Ivan Da Rocha Pitta
CARMO ALVES DE LIMA. María DO
Marina GALDINO DA ROCHA PITTA
Francisco Washington ARAUJO BARROS
Claudia DO Ó PESSOA
Manoel Odorico DE MORAES FILHO
Maira Galdino DA ROCHA PITTA
Original Assignee
Universidade Federal De Pernambuco - Ufpe
Universidade Federal Do Ceará - Ufc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidade Federal De Pernambuco - Ufpe, Universidade Federal Do Ceará - Ufc filed Critical Universidade Federal De Pernambuco - Ufpe
Publication of WO2013053034A2 publication Critical patent/WO2013053034A2/fr
Publication of WO2013053034A3 publication Critical patent/WO2013053034A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La présente invention concerne des composés dérivés de la 3-acrydinylméthyl-thiazolidine-2,4-dione, également appelés thiazacridines, ainsi que leurs procédés respectifs de synthèse chimique et leur utilisation thérapeutique dans le traitement du cancer.
PCT/BR2012/000421 2011-10-10 2012-10-24 Thiazacridines utilisées dans la thérapie anticancéreuse WO2013053034A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI1106333-5 2011-10-10
BRPI1106333 2011-10-10

Publications (2)

Publication Number Publication Date
WO2013053034A2 WO2013053034A2 (fr) 2013-04-18
WO2013053034A3 true WO2013053034A3 (fr) 2013-06-27

Family

ID=48082600

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2012/000421 WO2013053034A2 (fr) 2011-10-10 2012-10-24 Thiazacridines utilisées dans la thérapie anticancéreuse

Country Status (1)

Country Link
WO (1) WO2013053034A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024058A2 (fr) * 2002-09-10 2004-03-25 Conselho Nacional De Desenvolvimento Científico E Tecnológico - Cnpq Molecules a activite antitumorale, et procede de synthese chimique
WO2007109871A2 (fr) * 2006-03-24 2007-10-04 Universidade Federal De Pernambuco - Ufpe Dérives d'acridine a activite antitumorale

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024058A2 (fr) * 2002-09-10 2004-03-25 Conselho Nacional De Desenvolvimento Científico E Tecnológico - Cnpq Molecules a activite antitumorale, et procede de synthese chimique
WO2007109871A2 (fr) * 2006-03-24 2007-10-04 Universidade Federal De Pernambuco - Ufpe Dérives d'acridine a activite antitumorale

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
R.H. MOURAO ET AL.: "Synthesis and Biological Activity of Novel Acridinylidene and Benzylidene thiazolidinediones", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 40, 2005, pages 1129 - 1133, XP005113105 *
WILLIAM A. DENNY: "Acridine Derivatives as Chemotherapeutic Agents", CURRENT MEDICINAL CHEMISTRY, vol. 9, 2002, pages 1655 - 1665, XP009073854 *

Also Published As

Publication number Publication date
WO2013053034A2 (fr) 2013-04-18

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