WO2013049957A1 - Compound traditional chinese medicine eyedrop - Google Patents

Compound traditional chinese medicine eyedrop Download PDF

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Publication number
WO2013049957A1
WO2013049957A1 PCT/CN2011/001677 CN2011001677W WO2013049957A1 WO 2013049957 A1 WO2013049957 A1 WO 2013049957A1 CN 2011001677 W CN2011001677 W CN 2011001677W WO 2013049957 A1 WO2013049957 A1 WO 2013049957A1
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chinese medicine
vitamin
traditional chinese
eyedrop
heated
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PCT/CN2011/001677
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French (fr)
Chinese (zh)
Inventor
李代虹
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Li Daihong
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Priority to PCT/CN2011/001677 priority Critical patent/WO2013049957A1/en
Publication of WO2013049957A1 publication Critical patent/WO2013049957A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)

Definitions

  • the invention relates to a compound traditional Chinese medicine eye drops.
  • the patent provides an eye-catching eye drop. It is characterized by containing butanol, vitamins, boric acid, superior glycin, gasified ethyl sulfuric acid, sodium sulfate of cartilage, chrysanthemum and primordia.
  • the invention can quickly eliminate eye fatigue, increase eye nutrition and resistance, has special sterilization and anti-inflammatory ability, and has special effects on various eye diseases such as keratitis, bloodshot eyes and trachoma.
  • the patent of 95110140.4 is a traditional Chinese medicine eye drops, belonging to an eye medicine for treating viral conjunctivitis and electro-optic ophthalmia.
  • the eye drops have a significant effect on viral conjunctivitis and electro-optic ophthalmia.
  • the patent of 94107132.4 relates to a clear eye drops made of pure Chinese medicine. Its traditional Chinese medicine group mainly includes honeysuckle, wild chrysanthemum and mulberry leaves. It has the effects of clearing away heat and detoxifying, reducing redness and swelling, and clinical observation for treating conjunctivitis and keratitis. , iridocyclitis, scleritis, anterior chamber hemorrhage. Trachoma, electro-optic ophthalmia, the total effective rate is 92.97 %, which has fast treatment, short treatment and low cost. No toxic side effects, the effect is significantly better than other antibiotic eye drops.
  • the object of the present invention is to provide a compound Chinese medicine eye drops which is safe, high in efficacy, comprehensively in care and maintenance on the eyes, has no preservatives and has no side effects, and is characterized in that the weight ratio of the drug components is: Jiuliming 15g, Qianliqing 10g, Moon Moon Red 10g, Green Peel 10g, Rhizoma Coptidis 6g, Windproof 6g, Frosted Mulberry Leaves 8g, Honeysuckle 20g, Chrysanthemum 20g, Mi Menghua 15g, Su Hexiang 10g, Angelica 15g, Hazelnut 15g, Borneol 6g Cassia seed 8g, vitamin B 6 50mg, snow lotus 20g, vitamin E 50g.
  • the above drugs are heated to 800-1000 ml of water and heated to boiling for 20 to 40 minutes.
  • the filtrate is mixed with distilled water, and the ratio is as follows: liquid 15-25: distilled water 100.
  • the above drugs have the effects of eliminating eye fatigue, tonifying kidney and eyesight, clearing away heat and detoxifying, sterilizing and anti-inflammatory, fully supplementing eye nutrition and increasing resistance. They have the characteristics of fast curative effect, no toxic side effects and low cost, and are obviously superior to other antibiotics and other eye drops.
  • Jiuliming 15g Qianliqing 10g, Moon Moon Red 10g, Green Peel 10g, Rhizoma Coptidis 6g, Windproof 6g, Frosted Mulberry Leaves 8g, Honeysuckle 20g, Chrysanthemum 20g, Mi Menghua 15g, Su Hexiang 10g, Angelica 15g, Hazelnut 15g, Borneol 6g Cassia seed 8g, vitamin B 6 50mg, snow lotus 20g, vitamin E 50g.
  • the above drug is heated to 900 ml of water and heated to boiling for 35 minutes.
  • the filtrate is mixed with distilled water.
  • the preparation ratio is: liquid 15-25: distilled water 100.

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Disclosed is a compound traditional Chinese medicine eyedrop for eye protection,which is made of (by weight portion) Herba Senecionis Scandentis (15g), qianliqing (10g), Rosa chinensis (10g), Pericarpium Citri Reticulatae Viride (10g), Rhizoma Coptidis (6g), Raidix Saposhnikoviae (6g), Folium Mori (8g), Flos Lonicerae (20g), Flos Chrysanthemi (20g), Flos Buddlejae (15g), Styrax (10g), Radix Angelicae Sinensis (15g), Fructus Lycii (15g), Broneolum Syntheticum (6g), Semen Cassiae (8g), vitamin B6 (50mg), Saussurea involucrate (20g), vitamin E (50g).

Description

一种复方中药眼药水  Compound Chinese medicine eye drops
-、技术领域  -, technical field
本发明涉及一种复方中药眼药水。  The invention relates to a compound traditional Chinese medicine eye drops.
二、 背景技术 Second, the background technology
目前， 人们看电视、 电脑的时间大大增加， 需要保健眼药水对眼睛进行护 理，但目前保健眼药水存在功能不全、副作用大、含有防腐剂等缺点： 02134559.7 专利提供一种眼必静眼药水， 其特征是内含气丁醇、 维生素、 硼酸、 上等甘草 原素、 气化乙基硫酸、 软骨的硫酸钠、 杭菊原素及珍珠原素。 本发明能迅速消 除眼睛疲劳， 增加眼睛营养和抵抗力， 有特别的杀菌消炎能力， 对角膜炎、 充 血眼、 沙眼等多种眼疾有特效功能。 95110140.4专利为一种中药眼药水， 属于 一种治疗病毒性结膜炎和电光性眼炎的眼药。 由珍珠 1〜 2 5 g、 白银 1〜 2 5 g、 麦饭石 5 0〜 5 0 0 9、 水2 0 0〜 2 0 0 0 9 加热至沸 1 0〜 6 0分钟的 上清滤液与珍珠粉 1〜 2 5 g、 芒硝 1〜 1 0 0 g、 水 5〜 5 0 0 g, 加热至沸 1 0〜 4 0分钟的上清滤液混合后，加热浓缩至 1 0 0〜 1 0 0 0 g制成。该眼药 水对病毒性结膜炎和电光性眼炎有显著的疗效。 94107132.4专利涉及一种纯中 药制成的清明眼药水， 它的中药组方主要有金银花、 野菊花、 桑叶， 具有清热 解毒， 退赤消肿的功效， 绎临床观察对治疗结膜炎、 角膜炎， 虹膜睫状体炎， 巩膜炎， 前房积血。 沙眼、 电光性眼炎， 总有效率为 9 2 . 9 7 %， 其具有疗 效快， 疗程短， 成本低。 无毒副作用， 疗效明显优于其它抗生素眼药水。  At present, people spend a lot of time watching TV and computers, and need eye care to treat their eyes. However, the current eye drops have shortcomings such as insufficiency, side effects, and preservatives. 02134559.7 The patent provides an eye-catching eye drop. It is characterized by containing butanol, vitamins, boric acid, superior glycin, gasified ethyl sulfuric acid, sodium sulfate of cartilage, chrysanthemum and primordia. The invention can quickly eliminate eye fatigue, increase eye nutrition and resistance, has special sterilization and anti-inflammatory ability, and has special effects on various eye diseases such as keratitis, bloodshot eyes and trachoma. The patent of 95110140.4 is a traditional Chinese medicine eye drops, belonging to an eye medicine for treating viral conjunctivitis and electro-optic ophthalmia. From the pearl 1~ 2 5 g, silver 1~ 2 5 g, maifan stone 5 0~ 5 0 0 9 , water 2 0 0~ 2 0 0 0 9 heated to boiling 1 0~6 0 minutes of supernatant filtrate with Pearl powder 1~ 2 5 g, Glauber's salt 1~1 0 0 g, water 5~500 g, heated to boiling 1 0~4 0 minutes, the supernatant filtrate is mixed, heated and concentrated to 1 0 0~1 0 0 Made from 0 g. The eye drops have a significant effect on viral conjunctivitis and electro-optic ophthalmia. The patent of 94107132.4 relates to a clear eye drops made of pure Chinese medicine. Its traditional Chinese medicine group mainly includes honeysuckle, wild chrysanthemum and mulberry leaves. It has the effects of clearing away heat and detoxifying, reducing redness and swelling, and clinical observation for treating conjunctivitis and keratitis. , iridocyclitis, scleritis, anterior chamber hemorrhage. Trachoma, electro-optic ophthalmia, the total effective rate is 92.97 %, which has fast treatment, short treatment and low cost. No toxic side effects, the effect is significantly better than other antibiotic eye drops.
三、 发明内容 Third, the invention content
本发明的目的在于提供一种安全、 疗效高、 对眼睛进行全面护理保养、 无 防腐剂、 无副作用的复方中药眼药水， 其特征在于， 该药组份的重量配合比为： 九里明 15g、千里清 10g、月月红 10g、青皮 10g、黄连 6g、防风 6g、霜桑叶 8g、 金银花 20g、 菊花 20g、 密蒙花 15g、 苏合香 10g、 当归 15g、 枸杞子 15g、 冰片 6g、 决明子 8g、 维生素 B650mg、 雪莲 20g、 维生素 E50g。 The object of the present invention is to provide a compound Chinese medicine eye drops which is safe, high in efficacy, comprehensively in care and maintenance on the eyes, has no preservatives and has no side effects, and is characterized in that the weight ratio of the drug components is: Jiuliming 15g, Qianliqing 10g, Moon Moon Red 10g, Green Peel 10g, Rhizoma Coptidis 6g, Windproof 6g, Frosted Mulberry Leaves 8g, Honeysuckle 20g, Chrysanthemum 20g, Mi Menghua 15g, Su Hexiang 10g, Angelica 15g, Hazelnut 15g, Borneol 6g Cassia seed 8g, vitamin B 6 50mg, snow lotus 20g, vitamin E 50g.
以上药物加 800-1000ml水加热至沸 20~40分钟，取滤液与蒸馏水混合，配制比 为： 药液 15— 25:蒸馏水 100。 The above drugs are heated to 800-1000 ml of water and heated to boiling for 20 to 40 minutes. The filtrate is mixed with distilled water, and the ratio is as follows: liquid 15-25: distilled water 100.
以上药物具有消除眼睛疲劳、 补肾明目、 清热解毒、 杀菌消炎、 全面补充眼睛 营养及增加抵抗力的功效， 具有疗效快、 无毒副作用、 成本低的特点， 明显优 于其它抗生素等眼药水。 The above drugs have the effects of eliminating eye fatigue, tonifying kidney and eyesight, clearing away heat and detoxifying, sterilizing and anti-inflammatory, fully supplementing eye nutrition and increasing resistance. They have the characteristics of fast curative effect, no toxic side effects and low cost, and are obviously superior to other antibiotics and other eye drops.
四、 具体实施方式 Fourth, the specific implementation
实施例 1： Example 1:
九里明 15g、千里清 10g、月月红 10g、青皮 10g、黄连 6g、防风 6g、霜桑叶 8g、 金银花 20g、 菊花 20g、 密蒙花 15g、 苏合香 10g、 当归 15g、 枸杞子 15g、 冰片 6g、 决明子 8g、 维生素 B650mg、 雪莲 20g、 维生素 E50g。 Jiuliming 15g, Qianliqing 10g, Moon Moon Red 10g, Green Peel 10g, Rhizoma Coptidis 6g, Windproof 6g, Frosted Mulberry Leaves 8g, Honeysuckle 20g, Chrysanthemum 20g, Mi Menghua 15g, Su Hexiang 10g, Angelica 15g, Hazelnut 15g, Borneol 6g Cassia seed 8g, vitamin B 6 50mg, snow lotus 20g, vitamin E 50g.
以上药物加 900ml水加热至沸 35分钟， 取滤液与蒸馏水混合， 配制比为： 药液 15— 25:蒸馏水 100。 The above drug is heated to 900 ml of water and heated to boiling for 35 minutes. The filtrate is mixed with distilled water. The preparation ratio is: liquid 15-25: distilled water 100.

Claims

1、 一种复方中药眼药水， 其特征在于， 该药组份的重量配合比为:九里明 15g、 千里清 10g、月月红 10g、青皮 10g、黄连 6g、防风 6g、霜桑叶 8g、金银花 20g、 菊花 20g、 密蒙花 15g、 苏合香 10g、 当归 15g、 枸杞子 15g、 冰片 6g、 决明子 8g、 维生素 B650mg、 雪莲 20g、 维生素 E50g; 1. A compound Chinese medicine eye drops, characterized in that the weight ratio of the drug component is: Jiuliming 15g, Qianliqing 10g, Yueyuehong 10g, green skin 10g, berberine 6g, windproof 6g, frost mulberry leaf 8g, 20g of honeysuckle, 20g of chrysanthemum, 15g of dense flower, 10g of Suhexiang, 15g of angelica, 15g of medlar, 6g of borneol, 8g of cassia seed, 650mg of vitamin B, 20g of snow lotus, 50g of vitamin E;
以上药物加 800-1000ml水加热至沸 20~40分钟，取滤液与蒸馏水混合，配 制比为： 药液 15— 25:蒸馏水 100。  The above drugs are heated to 800-1000 ml of water and heated to boiling for 20 to 40 minutes. The filtrate is mixed with distilled water, and the ratio is as follows: liquid 15-25: distilled water 100.
PCT/CN2011/001677 2011-10-08 2011-10-08 Compound traditional chinese medicine eyedrop WO2013049957A1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107510715A (en) * 2016-06-15 2017-12-26 江苏吉贝尔药业股份有限公司 A kind of Flos Buddlejae extract eye-drops preparations and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1395959A (en) * 2002-08-14 2003-02-12 庄景云 Eyedrops 'Yanbijing'
CN101049359A (en) * 2007-04-11 2007-10-10 程艳蕊 Eyedrop of Chinese traditional medicine for treating ophthalmic diseases, and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1395959A (en) * 2002-08-14 2003-02-12 庄景云 Eyedrops 'Yanbijing'
CN101049359A (en) * 2007-04-11 2007-10-10 程艳蕊 Eyedrop of Chinese traditional medicine for treating ophthalmic diseases, and preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GU, WANZHANG: "Miscellany of traditional Chinese medicine commonly used in ophthalmology", AEROSPACE MEDICINE, vol. 15, no. 3, March 2004 (2004-03-01), pages 185 - 187 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107510715A (en) * 2016-06-15 2017-12-26 江苏吉贝尔药业股份有限公司 A kind of Flos Buddlejae extract eye-drops preparations and preparation method thereof

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