WO2013022410A3 - Production method for effervescent formulations comprising dexketoprofen - Google Patents

Production method for effervescent formulations comprising dexketoprofen Download PDF

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Publication number
WO2013022410A3
WO2013022410A3 PCT/TR2012/000130 TR2012000130W WO2013022410A3 WO 2013022410 A3 WO2013022410 A3 WO 2013022410A3 TR 2012000130 W TR2012000130 W TR 2012000130W WO 2013022410 A3 WO2013022410 A3 WO 2013022410A3
Authority
WO
WIPO (PCT)
Prior art keywords
dexketoprofen
production method
effervescent formulations
effervescent
formulations
Prior art date
Application number
PCT/TR2012/000130
Other languages
French (fr)
Other versions
WO2013022410A2 (en
Inventor
Mahmut Bilgic
Original Assignee
Mahmut Bilgic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahmut Bilgic filed Critical Mahmut Bilgic
Publication of WO2013022410A2 publication Critical patent/WO2013022410A2/en
Publication of WO2013022410A3 publication Critical patent/WO2013022410A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Abstract

The present invention relates to a production method used for production of effervescent formulations comprising dexketoprofen and the effervescent formulations obtained by this method.
PCT/TR2012/000130 2011-08-08 2012-08-08 Production method for effervescent formulations comprising dexketoprofen WO2013022410A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR201107834 2011-08-08
TR2011/07834 2011-08-08

Publications (2)

Publication Number Publication Date
WO2013022410A2 WO2013022410A2 (en) 2013-02-14
WO2013022410A3 true WO2013022410A3 (en) 2013-04-11

Family

ID=47045135

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2012/000130 WO2013022410A2 (en) 2011-08-08 2012-08-08 Production method for effervescent formulations comprising dexketoprofen

Country Status (1)

Country Link
WO (1) WO2013022410A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201723035A2 (en) * 2017-12-29 2019-07-22 Neutec Ar Ge Sanayi Ve Ticaret Anonim Sirketi Dexketoprofen delayed release composition.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942039A (en) * 1989-05-09 1990-07-17 Miles Inc. Effervescent analgesic antacid composition having reduced sodium content
EP0396972A2 (en) * 1989-05-09 1990-11-14 Bayer Ag An aqueous granulation solution and a method of tablet granulation
WO1994011332A1 (en) * 1992-11-10 1994-05-26 Laboratorios Menarini S.A. A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent
US5866162A (en) * 1993-08-10 1999-02-02 Smithkline Beecham P.L.C. Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1359614A (en) 1971-04-06 1974-07-10 Dev Et De Rech Soc Fr De Method for the manufacture of effervescent tablets
ES2124196B1 (en) 1997-06-04 1999-12-01 Menarini Lab PROCEDURE FOR THE MANUFACTURE OF A SEMI-SOLID PHARMACEUTICAL FORM CONTAINING DEXKETOPROPHEN TROMETAMOL AND ITS USE IN THE TOPICAL TREATMENT OF INFLAMMATION.
DE19822036A1 (en) 1998-05-15 1999-11-18 Bayer Ag Effervescent pharmaceutical composition with improved stability
KR100884493B1 (en) 2000-12-19 2009-02-18 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 Method and compositions employing formulations of lecithin oils and NSAIDs for protecting the gastrointestinal tract and providing enhanced therapeutic activity
PT1312355E (en) 2001-11-20 2003-10-31 Applied Pharma Res NON-EFFERVESCENT PHARMACEUTICAL COMPOSITIONS IN WATER COMPREHENDING ANTI-INFLAMMATORY DRUGS NAO-STEROIDES
ITFI20020144A1 (en) 2002-08-01 2004-02-02 Menarini Farma Ind STABILIZED TOPICAL FORMULATIONS CONTAINING KETOPROFENE.
ITFI20030070A1 (en) 2003-03-18 2004-09-19 Berlin Chemie Ag STABILIZED TOPICAL FORMULATIONS CONTAINING KETOPROFENE
EP1488787A1 (en) 2003-06-20 2004-12-22 Berlin-Chemie Ag Topical stabilized formulations containing ketoprofen
AU2007253083B2 (en) 2006-05-19 2012-07-19 Norbrook Laboratories Limited Stable aqueous suspension having palatable taste

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942039A (en) * 1989-05-09 1990-07-17 Miles Inc. Effervescent analgesic antacid composition having reduced sodium content
EP0396972A2 (en) * 1989-05-09 1990-11-14 Bayer Ag An aqueous granulation solution and a method of tablet granulation
WO1994011332A1 (en) * 1992-11-10 1994-05-26 Laboratorios Menarini S.A. A novel arylpropionic derivative, a process for the preparation and the use thereof as an analgesic agent
US5866162A (en) * 1993-08-10 1999-02-02 Smithkline Beecham P.L.C. Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple

Also Published As

Publication number Publication date
WO2013022410A2 (en) 2013-02-14

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