WO2013005195A1 - Aneurysm occluder - Google Patents

Aneurysm occluder Download PDF

Info

Publication number
WO2013005195A1
WO2013005195A1 PCT/IB2012/053483 IB2012053483W WO2013005195A1 WO 2013005195 A1 WO2013005195 A1 WO 2013005195A1 IB 2012053483 W IB2012053483 W IB 2012053483W WO 2013005195 A1 WO2013005195 A1 WO 2013005195A1
Authority
WO
WIPO (PCT)
Prior art keywords
aneurysm
housing
occluder
aneurysm occluder
strands
Prior art date
Application number
PCT/IB2012/053483
Other languages
French (fr)
Inventor
Jayandiran Pillai
Original Assignee
Jayandiran Pillai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jayandiran Pillai filed Critical Jayandiran Pillai
Publication of WO2013005195A1 publication Critical patent/WO2013005195A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12159—Solid plugs; being solid before insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm

Definitions

  • This invention relates to an aneurysm occluder, and more specifically but not exclusively to an endovascular aneurysm occluder that can be inserted into an aneurysm cavity by using endovascular surgical procedures.
  • An aneurysm is an excessive swelling of a wall segment of an artery and occurs when a wall segment of an artery weakens.
  • the pressure of blood flowing through the artery creates the swelling at the weakened wall section.
  • the swelling is commonly referred to as an aneurysm cavity or aneurysm sac.
  • Endovascular Aneurysm Repair is a corrective surgical procedure to repair an aneurysm of the aorta, which involves insertion of a vascular prosthesis, commonly referred to as a stent graft, which provides an artificial lumen for blood to flow though thereby immediately taking pressure off of the damaged portion of the blood vessel, which will itself thrombose in time.
  • the procedure is performed percutaneously by making two small incisions in the groin to expose the femoral arteries and feeding a synthetic stent graft through these arteries with catheters and guide-wires until the stent graft is positioned.
  • the damaged part of the blood vessel is internally lined and the stent graft, in the form of a tube, attaches, by radial force at either end to the normal proximal and distal arteries.
  • the vascular prosthesis must be attached to the blood vessel in such a way that there is a strong, tight seal around the normal proximal and distal artery so that blood will not escape into the aneurysm sac.
  • An ENDOLEAK may occur in up to 20% of all cases and is considered to be a failure of treatment and may be life-threatening.
  • ENDOLEAK can be treated in a variety of ways.
  • One way to treat ENDOLEAK is by open surgical repair and complete replacement of the stent graft. Open surgical repair and the insertion of a new graft carry a high operative mortality rate. Inducing thrombosis is often a successful way of treating the ENDOLEAK.
  • Thrombosis can be induced by injecting a liquid embolic agent, containing a biocompatible polymer, into the ENDOLEAK sac.
  • Thrombosis can also be induced in aneurysms by a procedure called endovascular coiling.
  • Endovascular coiling involves packing platinum coils into the aneurysm sac, through a catheter, to restrict blood circulation whereby the restricted blood circulation induces thrombosis.
  • a disadvantage of injecting a liquid embolic agent into the ENDOLEAK sac is that the biocompatible polymer dissolves over time and is absorbed into the blood stream.
  • a disadvantage of endovascular coiling is that aneurysms are often incompletely treated and carry a risk of aneurysm recurrence. In addition, coils are smaller in size to the aneurysm sac and may not fill the aneurysm sac completely.
  • an aneurysm occluder for occluding and enhancing thrombosis of an aneurysm cavity, comprising:
  • the housing having a plurality of strands woven to form a mesh
  • the disc-shaped insert located within the housing, the disc-shaped insert enhancing occlusion in an aneurysm cavity.
  • a first securing means is located at an end of the housing for gathering and securing the strands together.
  • the first securing means may also be used to position the aneurysm occlude within the aneurysm cavity.
  • the housing prefferably has a tubular shape.
  • the housing may have an expanded preset configuration shaped to create an occlusion in the aneurysm cavity, and a deformable configuration for insertion of the aneurysm occluder into the aneurysm cavity.
  • the housing may be at least 6 centimeters in length and at least 2 centimeters wide.
  • the housing may be compressed or elongated in length and/or breadth to fit the aneurysm cavity in situ.
  • the housing may have a memory property wherein the aneurysm occluder tends to return to the expanded preset configuration when unconstrained.
  • the housing prefferably has a smaller diameter and a longer length when constrained to a deformable configuration.
  • second securing means located at an end of the housing opposite the first securing means, the second securing means is for gathering and securing the strands together.
  • the first and second securing means may be in the form of a cap.
  • the cap may have a threaded bore for screwing the cap to the housing.
  • the strands may be metallic strands.
  • the metallic strands may stainless steel or nickel titanium.
  • the disc-shaped inserts may be polytetrafluoroethylene (PTFE).
  • the disc-shaped inserts there is provided for the disc-shaped inserts to have a diameter similar to the diameter of the housing.
  • the disc-shaped inserts may be positioned at opposite ends of the housing, and/or at various intervals therebetween, within the housing.
  • the discshaped inserts are at least 1.5 to 2 centimeters apart.
  • Figure 1 is a perspective view of an aneurysm occluder in accordance with the present invention
  • Figure 2 is a side view of the aneurysm occluder of Figure 1 ;
  • Figure 3 is a top view of the aneurysm occluder of Figures 1 and 2.
  • an aneurysm occluder is generally indicated by reference numeral 1.
  • the aneurysm occluder 1 has a housing 2 which consists of a plurality of metallic strands woven to form a mesh.
  • the strands may be stainless steel of nickel titanium.
  • the occluder 1 further has first securing means 4 which is located at an end of the housing 2 for gathering and securing the strands together.
  • a plurality of disc-shaped inserts 3 is located within the housing 2 and secured to the housing 2. The plurality of disc-shaped inserts 3 are placed at least 2 centimeters apart and enhance the clotting function of the aneurysm occluder .
  • first securing means 4 At one end of the housing 2, which is tubular in shape, there is a first securing means 4 to gather and secure the strands at that end of the housing 2 together and prevent the strands from loosening.
  • the strands at the opposite end of the housing 2 are gathered and secured to each other by a second securing means 4.
  • the first and second securing means 4 cause the housing 2 to have a tubular shape with closed ends.
  • the housing 2 When the aneurysm occluder 1 is not in use the housing 2 has an expanded preset configuration. When either a tensile force in an axial direction, or a compression force in a radial direction is applied to the housing 2, the housing 2 is deformed to have a smaller diameter and a longer length. The housing 2 is then in its reversibly deformed configuration.
  • the metallic strands have shape memory which lets the aneurysm occluder 1 return to the expanded preset configuration when unconstrained.
  • the stands' shape memory is also very important for when the occluder 1 is placed in an aneurysm cavity as the shape memory causes the occluder 1 to expand, from its deformable configuration during deployment, to take the shape of the cavity and thereby fill the entire cavity.
  • the first and second securing means 4 are in the form of a cap with a threaded bore. Each cap 4 is secured to the ends of the housing 2 by screwing it over the strands' loose ends at each end of the housing 2.
  • the disc-shaped inserts 3 which are circular in shape and made of polytetrafluoroethylene, have a diameter similar to the housing 2 in an unconstrained state. In a preferred embodiment there are three disc-shaped inserts 3 facing each other and spaced along the length of the housing 2. It will, however, be appreciated that any amount may be used. Each disc-shaped insert 3 is, at its circumference, secured to the housing 2 by a fine strand.
  • the occluder 1 In use, the occluder 1 is deformed to its reversibly deformed configuration for easy insertion into an aneurysm cavity. The deformation causes the disc-shaped inserts 3 to collapse and rotate by 90° so as to lie parallel to each other. The occluder 1 is then placed in the aneurysm cavity and allowed to expand and fill the entire cavity. The mesh housing and disc-shaped inserts 3 encourage blood clotting which relieves the pressure on the aneurysm wall.
  • This invention thus provides an aneurysm occluder which can fill the entire cavity of an aneurysm.
  • the larger holes in the mesh will also provide for easy deformation of the aneurysm occluder for insertion into an aneurysm cavity. It will be readily appreciated by persons skilled in the art that when the aneurysm occlude 1 is constrained in the aneurysm cavity, the space defined by the inserts acts as a high resistance closed cavity that prevents flow of blood and promotes thrombosis.

Abstract

This invention relates to an aneurysm occluder, and more specifically but not exclusively to an endovascular aneurysm occluder that can be inserted into an aneurysm cavity by using endovascular surgical procedures. In accordance with the invention, there is provided an aneurysm occluder for occluding and enhancing thrombosis of an aneurysm cavity comprising: a housing, the housing consisting of a plurality of strands woven to form a mesh; first securing means located at an end or the housing for gathering and securing the strands together; and a plurality of disc-shaped inserts located within the housing and secured to the housing, the plurality of disc-shaped inserts enhancing the occlusion of an aneurysm cavity.

Description

ANEURYSM OCCLUDER
FIELD OF THE INVENTION This invention relates to an aneurysm occluder, and more specifically but not exclusively to an endovascular aneurysm occluder that can be inserted into an aneurysm cavity by using endovascular surgical procedures.
BACKGROUND TO THE INVENTION
An aneurysm is an excessive swelling of a wall segment of an artery and occurs when a wall segment of an artery weakens. The pressure of blood flowing through the artery creates the swelling at the weakened wall section. The swelling is commonly referred to as an aneurysm cavity or aneurysm sac. As the size of the aneurysm increases, the risk of rupture increases, the resultant rupture causing internal bleeding which may result in severe complications and even death.
Endovascular Aneurysm Repair ("EVAR") is a corrective surgical procedure to repair an aneurysm of the aorta, which involves insertion of a vascular prosthesis, commonly referred to as a stent graft, which provides an artificial lumen for blood to flow though thereby immediately taking pressure off of the damaged portion of the blood vessel, which will itself thrombose in time. The procedure is performed percutaneously by making two small incisions in the groin to expose the femoral arteries and feeding a synthetic stent graft through these arteries with catheters and guide-wires until the stent graft is positioned. The damaged part of the blood vessel is internally lined and the stent graft, in the form of a tube, attaches, by radial force at either end to the normal proximal and distal arteries. The vascular prosthesis must be attached to the blood vessel in such a way that there is a strong, tight seal around the normal proximal and distal artery so that blood will not escape into the aneurysm sac. In practice it is often difficult to attach the stent graft to the ends of the blood vessel in such a way that there is a permanent strong, tight seal around the proximal and distal artery and blood flow into the aneurysm sac ("ENDOLEAK") may occur. An ENDOLEAK may occur in up to 20% of all cases and is considered to be a failure of treatment and may be life-threatening.
ENDOLEAK can be treated in a variety of ways. One way to treat ENDOLEAK is by open surgical repair and complete replacement of the stent graft. Open surgical repair and the insertion of a new graft carry a high operative mortality rate. Inducing thrombosis is often a successful way of treating the ENDOLEAK.
Thrombosis can be induced by injecting a liquid embolic agent, containing a biocompatible polymer, into the ENDOLEAK sac. Thrombosis can also be induced in aneurysms by a procedure called endovascular coiling. Endovascular coiling involves packing platinum coils into the aneurysm sac, through a catheter, to restrict blood circulation whereby the restricted blood circulation induces thrombosis. A disadvantage of injecting a liquid embolic agent into the ENDOLEAK sac is that the biocompatible polymer dissolves over time and is absorbed into the blood stream. A disadvantage of endovascular coiling is that aneurysms are often incompletely treated and carry a risk of aneurysm recurrence. In addition, coils are smaller in size to the aneurysm sac and may not fill the aneurysm sac completely. OBJECT OF THE INVENTION
It is accordingly an object of the invention to provide an aneurysm occluder that will, at least partially, alleviate the disadvantages mentioned above, and/or will provide a useful alternative to existing strategies and treatment regimens.
SUMMARY OF THE INVENTION
In accordance with the invention, there is provided an aneurysm occluder for occluding and enhancing thrombosis of an aneurysm cavity, comprising:
- a housing;
- the housing having a plurality of strands woven to form a mesh; and
- a disc-shaped insert located within the housing, the disc-shaped insert enhancing occlusion in an aneurysm cavity.
A first securing means is located at an end of the housing for gathering and securing the strands together. The first securing means may also be used to position the aneurysm occlude within the aneurysm cavity.
There is provided for the housing to have a tubular shape.
There is also provided for the housing to have an expanded preset configuration shaped to create an occlusion in the aneurysm cavity, and a deformable configuration for insertion of the aneurysm occluder into the aneurysm cavity. The housing may be at least 6 centimeters in length and at least 2 centimeters wide. The housing may be compressed or elongated in length and/or breadth to fit the aneurysm cavity in situ. There is further provided for the housing to have a memory property wherein the aneurysm occluder tends to return to the expanded preset configuration when unconstrained.
There is yet further provided for the housing to have a smaller diameter and a longer length when constrained to a deformable configuration.
There is also provided for second securing means located at an end of the housing opposite the first securing means, the second securing means is for gathering and securing the strands together.
The first and second securing means may be in the form of a cap. The cap may have a threaded bore for screwing the cap to the housing. The strands may be metallic strands.
The metallic strands may stainless steel or nickel titanium. The disc-shaped inserts may be polytetrafluoroethylene (PTFE).
There is provided for the disc-shaped inserts to have a diameter similar to the diameter of the housing. The disc-shaped inserts may be positioned at opposite ends of the housing, and/or at various intervals therebetween, within the housing. There is also provided for the disc-shaped inserts to be at their circumference secured to the housing so that the disc-shaped discs face the longitudinal direction of the housing. Alternatively, the disc-shaped inserts face the horizontal direction of the housing. The discshaped inserts are at least 1.5 to 2 centimeters apart. These and other features of the invention are described in more detail below. BRIEF DESCRIPTION OF DRAWINGS
One embodiment of the invention is described below, by way of example only, and with reference to the accompanying drawings in which:
Figure 1 : is a perspective view of an aneurysm occluder in accordance with the present invention;
Figure 2: is a side view of the aneurysm occluder of Figure 1 ; and
Figure 3: is a top view of the aneurysm occluder of Figures 1 and 2.
DETAILED DESCRIPTION OF THE DRAWINGS
With reference to the drawings, an aneurysm occluder is generally indicated by reference numeral 1.
The aneurysm occluder 1 has a housing 2 which consists of a plurality of metallic strands woven to form a mesh. The strands may be stainless steel of nickel titanium. The occluder 1 further has first securing means 4 which is located at an end of the housing 2 for gathering and securing the strands together. A plurality of disc-shaped inserts 3 is located within the housing 2 and secured to the housing 2. The plurality of disc-shaped inserts 3 are placed at least 2 centimeters apart and enhance the clotting function of the aneurysm occluder . At one end of the housing 2, which is tubular in shape, there is a first securing means 4 to gather and secure the strands at that end of the housing 2 together and prevent the strands from loosening. The strands at the opposite end of the housing 2 are gathered and secured to each other by a second securing means 4. The first and second securing means 4 cause the housing 2 to have a tubular shape with closed ends.
When the aneurysm occluder 1 is not in use the housing 2 has an expanded preset configuration. When either a tensile force in an axial direction, or a compression force in a radial direction is applied to the housing 2, the housing 2 is deformed to have a smaller diameter and a longer length. The housing 2 is then in its reversibly deformed configuration. The metallic strands have shape memory which lets the aneurysm occluder 1 return to the expanded preset configuration when unconstrained. The stands' shape memory is also very important for when the occluder 1 is placed in an aneurysm cavity as the shape memory causes the occluder 1 to expand, from its deformable configuration during deployment, to take the shape of the cavity and thereby fill the entire cavity.
The first and second securing means 4 are in the form of a cap with a threaded bore. Each cap 4 is secured to the ends of the housing 2 by screwing it over the strands' loose ends at each end of the housing 2.
The disc-shaped inserts 3, which are circular in shape and made of polytetrafluoroethylene, have a diameter similar to the housing 2 in an unconstrained state. In a preferred embodiment there are three disc-shaped inserts 3 facing each other and spaced along the length of the housing 2. It will, however, be appreciated that any amount may be used. Each disc-shaped insert 3 is, at its circumference, secured to the housing 2 by a fine strand.
In use, the occluder 1 is deformed to its reversibly deformed configuration for easy insertion into an aneurysm cavity. The deformation causes the disc-shaped inserts 3 to collapse and rotate by 90° so as to lie parallel to each other. The occluder 1 is then placed in the aneurysm cavity and allowed to expand and fill the entire cavity. The mesh housing and disc-shaped inserts 3 encourage blood clotting which relieves the pressure on the aneurysm wall.
This invention thus provides an aneurysm occluder which can fill the entire cavity of an aneurysm. The larger holes in the mesh will also provide for easy deformation of the aneurysm occluder for insertion into an aneurysm cavity. It will be readily appreciated by persons skilled in the art that when the aneurysm occlude 1 is constrained in the aneurysm cavity, the space defined by the inserts acts as a high resistance closed cavity that prevents flow of blood and promotes thrombosis.
It will be appreciated that many variations are possible with the present embodiment according to the invention without departing from the scope or spirit of the invention.

Claims

1. An aneurysm occluder, for occluding and enhancing thrombosis of an aneurysm cavity, comprising:
- a housing,
- the housing having a plurality of strands woven to form a mesh; and
- a disc-shaped insert located within the housing, the disc-shaped insert enhancing occlusion in an aneurysm cavity.
2. The aneurysm occluder, as claimed in claim 1 , wherein a first securing means is located at an end of the housing for gathering and securing the strands together.
3. The aneurysm occlude as claimed in claim 2, wherein the first securing means is used to position the aneurysm occluder within the aneurysm cavity
4. The aneurysm occluder, as claimed in any one of the preceding claims, wherein the housing has a tubular shape.
5. The aneurysm occluder, as claimed in any one of the preceding claims, wherein the housing is at least 6 centimeters in length and at least 2 centimeters wide, the housing allowing for reversible defomation by compression or elongation in length and/or breadth of the housing to fit the aneurysm cavity in situ.
6. The aneurysm occluder, as claimed in any one of the preceding claims, wherein the housing has an expanded preset configuration shaped to create an occlusion in the aneurysm cavity, and a deformable configuration for insertion of the aneurysm occluder into the aneurysm cavity.
7. The aneurysm occluder, as claimed in claim 6, wherein the housing has a memory property which causes the aneurysm occluder to tend to return to the expanded preset configuration when unconstrained.
8. The aneurysm occluder, as claimed in claim 6, wherein the housing has a smaller diameter and a longer length when constrained to the deformable configuration.
9. The aneurysm occluder, as claimed in any one of claims 2 to 8, wherein a second securing means is located at an end of the housing opposite the first securing means, the second securing means functioning, in use, to gather and secure the strands together.
10. The aneurysm occluder, as claimed in claim 9, wherein the first and second securing means are in the form of a cap.
1 . The aneurysm occluder, as claimed in claim 10, wherein the cap has a threaded bore for screwing the cap to the housing.
12. The aneurysm occluder, as claimed in any one of the preceding claims, wherein the strands are metallic strands.
13. The aneurysm occluder, as claimed in claim 12, wherein the metallic strands are stainless steel strands or nickel titanium strands.
14. The aneurysm occluder, as claimed in any of the preceding claims, wherein the discshaped inserts are made of polytetrafluoroethylene (PTFE).
15. The aneurysm occluder, as claimed in any of the preceding claims, wherein the discshaped inserts have a diameter similar to the diameter of the housing.
16. The aneurysm occluder, as claimed in any one of the preceding claims, wherein the discshaped inserts are secured, at their circumference, to the housing at opposite ends thereof, so that the disc-shaped inserts face the longitudinal direction of the housing.
17. The aneurysm occluder, as claimed in any one of the preceding claims, wherein the discshaped inserts are secured, at their circumference, to the housing at opposite ends thereof, so that the disc-shaped inserts face the horizontal direction of the housing.
. An aneurysm occluder substantially as any one embodiment described herein with reference to and as illustrated in the accompanying diagrammatic drawings.
PCT/IB2012/053483 2011-07-07 2012-07-06 Aneurysm occluder WO2013005195A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA2011/05004 2011-07-07
ZA201105004 2011-07-07

Publications (1)

Publication Number Publication Date
WO2013005195A1 true WO2013005195A1 (en) 2013-01-10

Family

ID=46682862

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/053483 WO2013005195A1 (en) 2011-07-07 2012-07-06 Aneurysm occluder

Country Status (1)

Country Link
WO (1) WO2013005195A1 (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016125018A3 (en) * 2015-02-06 2016-10-13 Rapid Medical Ltd. Systems and methods for intravascular obstruction removal
CN106539606A (en) * 2017-01-05 2017-03-29 郭伟 A kind of false chamber plugging device
WO2017072692A1 (en) * 2015-10-28 2017-05-04 Jayandiran Pillai Aneurysm occluder
WO2017072695A1 (en) * 2015-10-28 2017-05-04 Jayandiran Pillai Aneurysm occluder
CN109069220A (en) * 2016-03-11 2018-12-21 Cerus血管内设备有限公司 plugging device
US10398441B2 (en) 2013-12-20 2019-09-03 Terumo Corporation Vascular occlusion
US11284901B2 (en) 2014-04-30 2022-03-29 Cerus Endovascular Limited Occlusion device
US11406404B2 (en) 2020-02-20 2022-08-09 Cerus Endovascular Limited Clot removal distal protection methods
US11471162B2 (en) 2015-12-07 2022-10-18 Cerus Endovascular Limited Occlusion device
US11564692B2 (en) 2018-11-01 2023-01-31 Terumo Corporation Occlusion systems
US11812971B2 (en) 2017-08-21 2023-11-14 Cerus Endovascular Limited Occlusion device
CN106539606B (en) * 2017-01-05 2024-04-30 中国人民解放军总医院 False cavity plugging device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110054519A1 (en) * 2008-03-26 2011-03-03 Malte Neuss Device for closing defects in the vascular system
US20110152993A1 (en) * 2009-11-05 2011-06-23 Sequent Medical Inc. Multiple layer filamentary devices or treatment of vascular defects

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110054519A1 (en) * 2008-03-26 2011-03-03 Malte Neuss Device for closing defects in the vascular system
US20110152993A1 (en) * 2009-11-05 2011-06-23 Sequent Medical Inc. Multiple layer filamentary devices or treatment of vascular defects

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10398441B2 (en) 2013-12-20 2019-09-03 Terumo Corporation Vascular occlusion
US11832824B2 (en) 2013-12-20 2023-12-05 Terumo Corporation Vascular occlusion
US11389174B2 (en) 2014-04-30 2022-07-19 Cerus Endovascular Limited Occlusion device
US11284901B2 (en) 2014-04-30 2022-03-29 Cerus Endovascular Limited Occlusion device
US11925368B2 (en) 2015-02-06 2024-03-12 Rapid Medical Ltd. Systems and methods for intravascular obstruction removal
US11083473B2 (en) 2015-02-06 2021-08-10 Rapid Medical Ltd. Systems and methods for intravascular obstruction removal
WO2016125018A3 (en) * 2015-02-06 2016-10-13 Rapid Medical Ltd. Systems and methods for intravascular obstruction removal
US11478251B2 (en) 2015-10-28 2022-10-25 Jayandiran Pillai Aneurysm occluder
WO2017072692A1 (en) * 2015-10-28 2017-05-04 Jayandiran Pillai Aneurysm occluder
EP3367926A4 (en) * 2015-10-28 2019-10-09 Jayandiran Pillai Aneurysm occluder
US11103250B2 (en) 2015-10-28 2021-08-31 Jayandiran Pillai Aneurysm occluder
WO2017072695A1 (en) * 2015-10-28 2017-05-04 Jayandiran Pillai Aneurysm occluder
US11471162B2 (en) 2015-12-07 2022-10-18 Cerus Endovascular Limited Occlusion device
US11648013B2 (en) 2016-03-11 2023-05-16 Cerus Endovascular Limited Occlusion device
CN109069220A (en) * 2016-03-11 2018-12-21 Cerus血管内设备有限公司 plugging device
CN106539606A (en) * 2017-01-05 2017-03-29 郭伟 A kind of false chamber plugging device
CN106539606B (en) * 2017-01-05 2024-04-30 中国人民解放军总医院 False cavity plugging device
US11812971B2 (en) 2017-08-21 2023-11-14 Cerus Endovascular Limited Occlusion device
US11564692B2 (en) 2018-11-01 2023-01-31 Terumo Corporation Occlusion systems
US11406404B2 (en) 2020-02-20 2022-08-09 Cerus Endovascular Limited Clot removal distal protection methods

Similar Documents

Publication Publication Date Title
WO2013005195A1 (en) Aneurysm occluder
US11291453B2 (en) Filamentary devices having a flexible joint for treatment of vascular defects
US11166731B2 (en) Systems and methods for treating aneurysms
JP7469323B2 (en) Filamentous Devices for the Treatment of Vascular Disorders - Patent application
AU748626B2 (en) Wire frame partial flow obstruction device for aneurysm treatment
US11806020B2 (en) Systems and methods for embolization of body structures
EP2939614B1 (en) Implantable medical device with twisted element
US20130204351A1 (en) Aneurysm Graft Devices And Methods
CN113573765A (en) Silk device for treating vascular defects
WO2014159746A1 (en) Aneurysm graft with stabilization
US20210346032A1 (en) Devices for treatment of vascular defects
US20220249098A1 (en) Filamentary devices for treatment of vascular defects
CN110301955A (en) Embolization device
US20210282789A1 (en) Multiple layer devices for treatment of vascular defects
US20220192678A1 (en) Filamentary devices for treatment of vascular defects
US11478251B2 (en) Aneurysm occluder

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12748054

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12748054

Country of ref document: EP

Kind code of ref document: A1