WO2012170596A1 - Procédé permettant d'augmenter l'efficacité d'entraînement - Google Patents

Procédé permettant d'augmenter l'efficacité d'entraînement Download PDF

Info

Publication number
WO2012170596A1
WO2012170596A1 PCT/US2012/041194 US2012041194W WO2012170596A1 WO 2012170596 A1 WO2012170596 A1 WO 2012170596A1 US 2012041194 W US2012041194 W US 2012041194W WO 2012170596 A1 WO2012170596 A1 WO 2012170596A1
Authority
WO
WIPO (PCT)
Prior art keywords
individual
breathing
training
oxygen
pap device
Prior art date
Application number
PCT/US2012/041194
Other languages
English (en)
Inventor
Matthew L. KRAUZA
Original Assignee
Krauza Matthew L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krauza Matthew L filed Critical Krauza Matthew L
Publication of WO2012170596A1 publication Critical patent/WO2012170596A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/22—Carbon dioxide-absorbing devices ; Other means for removing carbon dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A61M2016/1025—Measuring a parameter of the content of the delivered gas the O2 concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A61M2016/103—Measuring a parameter of the content of the delivered gas the CO2 concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/025—Helium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/205—Blood composition characteristics partial oxygen pressure (P-O2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/43—Composition of exhalation
    • A61M2230/432—Composition of exhalation partial CO2 pressure (P-CO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/43—Composition of exhalation
    • A61M2230/435—Composition of exhalation partial O2 pressure (P-O2)
    • A—HUMAN NECESSITIES
    • A63—SPORTS; GAMES; AMUSEMENTS
    • A63B—APPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
    • A63B2213/00—Exercising combined with therapy
    • A63B2213/005—Exercising combined with therapy with respiratory gas delivering means, e.g. O2

Definitions

  • the present invention relates to exercise training and, in particular, a method for reallocating oxygen consumption load between various muscle groups in the human body to improve exercise effectiveness, more particularly through the use of, optionally multiple, oxygen load shifting strategies during the course of training to extreme exertion approaching the safe limits of human exertion and/ or performance.
  • Oxygen supplementation can employ helium and oxygen gas mixtures.
  • helium oxygen mixtures may be used in refractory asthma (status asthmaticus) and stridor.
  • oxygen supplementation involving the use of pure oxygen is routinely used in sports, typically after an individual has undergone
  • a person undergoing exercise training enhances exercise performance by reallocating the distribution of inspired oxygen, in order to optimize the amount of oxygen delivered to exercising muscles while decreasing the amount of oxygen used by respiratory muscles.
  • the amount of oxygen absorbed by the lungs of a healthy individual during breathing is basically unaffected by the percentage of oxygen that is administered to an individual (or fraction of inspired oxygen) in the inhaled gas.
  • the routine uses of oxygen in sports may be of little value.
  • Reallocation of oxygen between muscle groups is the inventive approach. Healthy lungs deliver substantially the same amount of oxygen to body tissues whether the source of oxygen is air, which contains about 21% oxygen, or pure oxygen, that is, 100% oxygen.
  • HeCh helium gas and oxygen gas
  • PEEP Positive end expiratory pressure
  • This device does not provide for low resistance positive airway pressure ventilation to optimize the metabolism of exercising or recovering muscles.
  • the use of pure oxygen in sports to hasten recovery after exertion is of questionable value, and may actually be injurious, as prolonged use of a pure oxygen breathing gas can cause toxicity to the lungs. Moreover, such devices and their current techniques of use even do little or nothing to increase the effectiveness of recovery, despite their widespread use.
  • the present invention fulfills this need by providing methods of exercise training to improve exercise performance in an individual comprised of breathing a low-density gas comprised of a mixture of helium and oxygen (He0 2 ) gas during and/ or immediately after exercise training.
  • the methods of the present invention are particularly well suited for healthy individuals who wish to improve their exercise performance during exercise.
  • a method of exercise training to improve exercise performance in an individual comprising breathing a low-density gas comprised of a mixture of He0 2 gas by having an individual wear an interface which delivers the HeCh gas mixture to the individual.
  • the interface is connected via a tubing circuit to a positive airway pressure (PAP) assist ventilator device which is connected to flexible tubing connected through a pressure regulator to a liquid gas source which supplies the He0 2 gas mixture to the PAP device.
  • PAP positive airway pressure
  • Both the interface and the tubing circuit comprise a breathing circuit.
  • the individual breaths the mixture of He02 gas during exercise training in order to reduce the work of breathing by the individual. In another embodiment, the individual breaths the mixture of He0 2 gas
  • the individual breaths the mixture of He0 2 gas during exercise training in order to reduce the work of breathing by the individual. In yet another most preferred embodiment, the individual breaths the mixture of He0 2 gas during and immediately after exercise training to allow for extreme training.
  • the individual breaths a hypoxic (fraction of inspired oxygen less than 21%) mixture of He0 2 gas during and immediately after exercise training to both reduce recovery time from the exercise training, while allowing for higher performance, hypoxic exercise training.
  • This method of exercise training increases the efficiency of body tissues at oxygen extraction from the circulatory system and can increase oxygen delivery to tissues by increasing the red blood cell mass, and altering the composition of the red blood cell / thus further enhancing performance during subsequent competitive activity.
  • At 21%the viscosity of the oxygen is low enough to cause a minimal pulmonary muscle load, yet stil provide enough oxygen to a normal person (who has not undergone hypoxic training) for training.
  • the inventive method of training an individual to improve performance in sports or other competitive activity by achieving a higher level of training for muscle groups associated with said competitive activity comprises having the individual breath a low-density gas mixture comprised of a mixture of helium and oxygen (He02).
  • the breathing of said low-density gas mixture is done while the individual is training.
  • the training is performed to a point of exertion, optionaly to a point reasonably approaching the limits of performance for the individual when it is desired to maximize the degree of muscle training.
  • the viscous resistance associated with breathing the low-density gas mixture is low as compared with the viscous resistance associated with breathing air.
  • the amount of oxygen consumed by the muscles involved with breathing is low as compared with consumption of oxygen of the muscles involved with breathing when the individual is breathing air.
  • the oxygen available for exercising the muscles being trained is increased to provide increased development of the muscles being trained as compared with the development associated with training while breathing air.
  • a method of simulating high altitude exercise training in an individual comprising breathing a low-density gas comprised of a mixture of helium gas and a hypoxic level of oxygen gas (He-hyp02) by having the individual wear an interface as described above which delivers the He-hyp0 2 gas mixture to the individual.
  • the interface is connected via a tubing circuit to a positive airway pressure (PAP) assist ventilator device as described above, which is connected to flexible tubing connected through a pressure regulator to a liquid gas source which supplies the He-hyp0 2 gas mixture to the PAP device.
  • PAP positive airway pressure
  • Fig. 1 is an illustration of an individual breathing a mixture of He0 2 gas or He-hyp02 gas via an interface connected to a positive airway pressure (PAP) assist ventilator device according to the embodiments of the invention.
  • PAP positive airway pressure
  • the present invention provides methods of training to improve athletic performance in an individual. More particularly, in accordance with the invention, the individual breaths a low-density gas comprised of a mixture of helium and oxygen (He0 2 ) gas during and/ or immediately after exercise training.
  • a low-density gas comprised of a mixture of helium and oxygen (He0 2 ) gas during and/ or immediately after exercise training.
  • He0 2 helium and oxygen
  • a method of exercise training to improve exercise performance in an individual 10 comprising breathing a low-density gas comprised of a mixture of helium and oxygen by having the individual 10 wear an interface 12 which delivers the He0 2 gas mixture to the individual 10.
  • the interface 12 is connected via a tubing circuit 14 to a positive airway pressure (PAP) assist ventilator device 16 which is connected to flexible tubing 18 connected through a pressure regulator 20 to a liquid gas source 22 which supplies the He0 2 gas mixture to the PAP device 16.
  • PAP positive airway pressure
  • Both the interface 12 and the tubing circuit 14 comprise a breathing circuit 24.
  • the inventive method is concerned with techniques for increasing the amount of oxygen available during training to a muscle groups to be trained, as well as improving the clearance of metabolic byproducts, of these muscle groups, by the circulatory and respiratory systems More particularly, the invention contemplates the shifting of oxygen demand from muscles which are not the objective of a particular exercise to muscles which are the objective of the exercise, while at the same time improving clearance of metabolic byproducts that can limit exercise performance, accordingly allowing the user to achieve a higher workload during training, than is otherwise possible, resulting in more extreme development of the muscles which are the objective of the exercise.
  • an athlete in training may spend time pushing the extreme development and performance of a first group of muscles at one time, and pushing the extreme development and performance of another group of muscles at another time, thus bringing a large group for muscles to an extreme point of development and performance.
  • oxygen demand fulfillment is shifted from the muscles involved in breathing to other muscles by reducing the effort, or metabolic work, of breathing. This means that more oxygen is available and therefore exercise and training can be taken to a more extreme level of high performance.
  • the viscosity of air or other gaseous fluid being breathed by an individual is the cause of significant viscous resistance. This is because the air carrying passages of the lungs are extremely small at the ends of the airways where the blood is oxygenated. Because they are so small, very significant viscous resistance is encountered, forcing the muscles involved in breathing to do much work, and, and, consequently, consume much oxygen.
  • this load is reduced through the use of low viscosity breathing gases during exercising periods of extreme physical exertion, or during a period of recovery immediately after extreme physical exertion.
  • the primary objective of the present invention is to use a low viscosity helium gas for the purpose of reducing oxygen demand by the muscles involved in breathing
  • the invention also contemplates the use of a mask with small input air passages, valves, or other type of resistive loading device, which provides resistance to breathing, communicating with the ambient air in order to increase the amount of work needed to breathe, for the purpose of developing the muscles associated with breathing during a different part of the training regimen, which different part has the objective of increasing the performance of breathing muscles by pushing them to extremes not normally encountered during exercise.
  • a mask with small input air passages, valves, or other type of resistive loading device which provides resistance to breathing, communicating with the ambient air in order to increase the amount of work needed to breathe, for the purpose of developing the muscles associated with breathing during a different part of the training regimen, which different part has the objective of increasing the performance of breathing muscles by pushing them to extremes not normally encountered during exercise.
  • enhanced performance of the lungs may not be an issue and such a part of the training regimen would not be necessary.
  • the He02 gas mixture provided in accordance with the present invention provides a fraction of inspired oxygen (F1O2) of about 21 % and a corresponding fraction of inspired helium (FiHe) of about 79%.
  • the interface 12 is comprised of a mask worn by the individual 10.
  • the mask may be a full-face mask, a nasal style mask, an oro-nasal style mask, a mouth-only style mask, a high flow nasal cannula or any other style mask capable of delivering gas and/ or pressure from the breathing circuit 24 to the individual 10.
  • the mask or the tubing system may have a fixed or a variable leak function, or valve system in which the breathing circuit vents exhaled breath into the atmosphere.
  • the system may also utilize cartridges oflLithium
  • CO2 carbon dioxide
  • the mask may be battery powered or externally powered and/ or may include a
  • transmitter for transmitting data between the mask and the PAP device 16.
  • the tubing circuit 14 may be made of a flexible, reinforced tube having adaptors (not shown) configured to fit into both the PAP device 16 and the interface 12.
  • the tubing circuit 14 is gas impermeable and may contain internal wires for transmitting electrical power and/ or data between the PAP device 16 and the interface 12.
  • an individual 10 breaths the mixture of He0 2 gas during exercise training in order to reduce the work of breathing by the individual 10.
  • an individual 10 breathes the mixture of HeCh gas at a pressureslightly greater than or equal to atmospheric pressure, immediately after exercise training to reduce recovery time from the exercise training or performance.
  • the liquid gas source 22 may be either an external high capacity liquid gas storage tank or a portable liquid gas canister.
  • the HeC1 ⁇ 2 gas mixture gas may be delivered into the breathing circuit 24 in either a closed configuration or an open configuration. In the closed
  • the He0 2 gas mixture is supplied directly to the PAP device 16 via flexible tubing 18 connected to a liquid gas source 22.
  • the PAP device 16 draws air from the surrounding environment at ambient atmospheric pressure into the breathing circuit 24.
  • the HeCte gas mixture may be delivered into the tubing circuit 14, into the interface 12, or into both the tubing circuit 14 and the interface 12.
  • the interface 12 or the tubing circuit 14 may contain an end tidal carbon dioxide (CO2) sensor safety override system capable of measuring CO2 levels in the breathing circuit 24. When unsafe levels of CO2 are detected, the CO2 sensor alters the PAP device 16 by altering system leak levels to allow for greater CO2 escape from the breathing circuit 24, by changing pressure or flow levels, or by terminating function of the PAP device 16.
  • CO2 end tidal carbon dioxide
  • the PAP device 16 may contain an oxygen (O2) sensor system capable of measuring the concentration of O2 in the breathing circuit 24 and communicating this information to an electronics system onboard the PAP device 16.
  • O2 oxygen
  • the PAP device 16 may contain internal flow sensors and pressure sensors capable of sensing variable inspiratory rates, expiratory rates and leak rates within the breathing circuit 24.
  • the PAP device 16 may have an internal electronic algorithm which can vary the pressure delivered within the breathing circuit 24 in order to maintain a desired pressure.
  • the PAP device 16 is capable of generating either continuous level or bi- level modes of respiratory pressures within the breathing circuit 24.
  • a continuous mode also referred to as continuous positive airway pressure
  • CPAP bi-level positive airway pressure
  • the PAP device 16 In a bi-level mode, also referred to as bi-level positive airway pressure (BiPAP), the PAP device 16 generates a bi-level respiratory pressure in which the PAP device 16 cycles between a higher inspiratory pressure and a lower expiratory pressure. Both the inspiratory pressure and the expiratory pressure can range from about 4 cm to about 30 cm of H 2 0 pressure (with the inspiratory pressure having a higher value than the expiratory pressure).
  • the PAP device 16 may be powered by an internal or external power supply for use in an alternating current wall plug or in an internal or external battery pack power supply.
  • the PAP device 16 is powered by a portable battery power source and the liquid gas source 22 is a portable liquid gas canister, making the entire low-resistance positive airway system portable and wearable by an individual.
  • the PAP device 16 can contain internal software which provides wireless capability for wireless communication, device control and transfer of information from the PAP device 16.
  • a method of simulating high altitude exercise training in an individual 10 comprising breathing a low-density gas comprised of a mixture of helium gas and a hypoxic level of oxygen gas (He-hyp0 2 ) by having an individual 10 wear an interface 12 as described above which delivers the He-hypCb gas mixture to the individual 10.
  • the interface 12 is connected via a tubing circuit 14 to a positive airway pressure (PAP) assist ventilator device 16 as described above, which is connected to flexible tubing 18 connected through a pressure regulator 20 to a liquid gas source 22 which supplies the He-hyp0 2 gas mixture to the PAP device 16.
  • PAP positive airway pressure
  • the He-hyp0 2 gas mixture provides a Fi0 2 , for example, optionally ranging from about 16% to about 20% and a corresponding FiHe ranging from about 82% to about 80%.
  • the He-hyp0 2 gas mixture gas may be delivered into the breathing circuit 24 in either a closed configuration or an open configuration.
  • the closed configuration the He-hyp0 2 gas mixture is supplied directly to the PAP device 16 via flexible tubing 18 which is connected to an external gas source 22 such as an external high capacity liquid gas storage tank.
  • an open configuration the PAP device 16 draws air from the surrounding environment at ambient atmospheric pressure into the breathing circuit 24 and helium gas is delivered into the breathing circuit 24 to dilute the Fi0 2 .
  • the helium gas can be delivered into the tubing circuit 14, the interface 12 or into both the tubing circuit 14 and the interface 12.
  • the helium gas is delivered to the interface 12 via flexible tubing 18 connected to a liquid gas source 22 such as a liquid helium gas supply.
  • the flow rate of the helium gas is controlled by an electronic pressure regulator 20 connected to the liquid helium gas supply via the flexible tubing 18.
  • the pressure regulator 20 is controlled by an electronics system of the PAP device 16.
  • the flow rate of the helium gas is varied according to an individual's minute ventilation rate.
  • the flow rate of the helium gas may also be controlled by the oxygen sensor system, pressure sensors, flow sensors or safety sensors.
  • the PAP device 16 may contain a pulse oxymetry safety override system consisting of a pulse oxymeter probe (not shown) worn by the individual 10 during exercise training.
  • the pulse oxymeter probe is capable of transmitting data either through wires or wirelessly from the oxymeter to the PAP device 16 electronics system in which a safety protocol is able to interrupt helium gas delivery to the interface 12 or alter PAP device 16 function if unsafe oxygen levels are detected in the individual 10.
  • the methods of the present invention improve exercise performance by reducing the work expended by respiratory muscles of the exercising individual. With reduced expenditure of energy by the respiratory muscles, the individual more efficiently clears CO2 from the lungs produced by exercising muscles and body tissues and provides more O2 to the exercising muscles and other body tissues.
  • the overall effect is to reduce the work of breathing caused by elevated respiratory system workloads experienced with training for competitive activities.
  • reducing the work of breathing during training using the methods of the present invention allows an individual to redirect metabolic energy from the respiratory muscles to the muscles of the individual which are undergoing training. This allows the individual to achieve higher performance levels due to increased metabolic efficiency.
  • Regular use of the methods of the present invention during and optionally immediately after exercise training leads to more rapid and higher levels of physical conditioning than could be achieved with traditional exercise training methods.
  • a positive airway pressure is used in feeding the helium/ oxygen mixture to the individual undergoing training. This further reduces the oxygen load associated with breathing during extreme exercise training.
  • the methods of the present invention reduce the work of breathing by an individual in two ways: breathing a He0 2 gas mixture during or immediately after exercise training and the use of positive airway pressure during or immediately after exercise training, as discussed below.
  • a mixture of HeCh gas has a lower resistance through the airways of an individual as compared to atmospheric air. This is due to the substitution of helium gas for nitrogen gas normally found in atmospheric air.
  • Helium gas has a lower density and viscosity, and thus a lower resistance through airway passages, than nitrogen gas.
  • the low-resistance HeCte gas mixture thus reduces the viscosity associated with turbulent and non turbulent gas flow in large airway passages, at airway branch points and in irregularly-shaped upper airway passages of an individual. This in turn reduces the force required to generate a given inspiratory or expiratory flow rate by an individual.
  • the positive airway pressure used by the methods of the present invention provides a positive pressure assist to an individual during inhalation, which reduces the resistive work required to transport gas through the irregularly-shaped upper airway passages of an individual.
  • the reduced work encountered by the individual allows the individual to generate higher tidal volumes with a smaller work load.
  • the positive end expiratory pressure achieved by using positive airway pressure prevents dynamic airway collapse during forced exhalation which allows for more efficient clearance of exhaled gas during exercise training.
  • the interface used in the methods of the present invention contains a leak system designed to use the positive pressure in the breathing circuit to wash exhaled CO2 from an individual's dead space, but may also use a CO2 scavenging material in the breathing circuit to achieve additional, or alternate CO2 extraction capacity.
  • an individual is able to improve the efficiency of their respiratory system by reducing the metabolic energy required to expel CO2 and oxygenate body tissues, reduce dynamic expiratory collapse of the small airways, improve clearance of deadspace CO 2 in the upper airways, and as a result expel more CO2 with each breath, which allows for lower respiratory rates and tidal volumes (further reducing the work of breathing) during and immediately after exercise training.
  • the methods of the present invention provide unexpected benefits to an individual that is undergoing exercise training or immediately recovering from exercise training such as (1) reduced work of breathing; (2) reduced fatigue levels; (3) less dyspnea (shortness of breath); (4) improved conditioning levels with repeated use compared to traditional exercise regimens; (5) improved recovery times after exercise; and (6) overall improved exercise performance.
  • the methods of the present invention provide the additional advantage of simulating altitude training and accordingly also provide unexpected benefits to an individual by easily simulating a high altitude, low O2 environment at sea level (or at any altitude).
  • This style of exercise will stimulate the bone marrow to produce a greater number of red blood cells allows.
  • Red blood cell structure is also changed by this style of exercise, resulting in an increased concentration of 2,3 Bisphosphogly eerie acid (2,3, BPG.) This results in allowing the red blood cell to more efficiently deliver oxygen to the body tissues.
  • Oxygen extraction by the body tissues is also improved by exposure to a hypoxic environment.
  • hypoxic conditioning in accordance with the invention results in increasing the number of red blood cells, thus increasing the oxygen and CO2 carrying capacity of the blood. This enables yet further extremes in training and conditioning resulting in further enhanced athletic performance.
  • the combination of hypoxic and low viscosity gases provides a multiple event which enables athletes to achieve extreme levels in the development of strength and endurance, and thus enable extreme performance.
  • Regular exposure to exercise in a hypoxic environment produces physiological changes in an individual which augments O2 delivery, O2
  • training may be carried beyond conventional levels, and due to the same, increased performance can be achieved during athletic competition.
  • trainers as in conventional training regimens, generally push athletes to high levels of performance, taking care, of course, not to allow the athlete to engage in activity which might endanger the well-being of the person being trained.
  • the methods of the present invention in addition to training for sports associated purposes such as competitive sports and mountaineering, may also be used by individuals in the military and in aerospace industries.

Abstract

Cette invention concerne des procédés d'entraînement physique permettant d'améliorer les performances d'un sujet en utilisant une pression positive expiratoire de faible résistance et des mélanges spécifiques de gaz pendant l'exercice ou immédiatement après. Les procédés consistent à porter une interface (masque) reliée par une tubulure à un dispositif de ventilation assistée de pression positive expiratoire (PAP). Le dispositif PAP est relié à une tubulure souple reliée par un régulateur de pression à une source de gaz liquide qui apporte le mélange de gaz. Les procédés consistent également à simuler un entraînement physique à haute altitude en utilisant le dispositif PAP avec un taux hypoxique d'oxygène dans le mélange gazeux. Les procédés de l'invention redistribuent l'oxygène entre les groupes musculaires, réduisent la fatigue et les épisodes de dyspnée, améliorent les niveaux de conditionnement et optimisent globalement l'entraînement à des niveaux extrêmes de performances.
PCT/US2012/041194 2011-06-07 2012-06-07 Procédé permettant d'augmenter l'efficacité d'entraînement WO2012170596A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/154,933 US20120315614A1 (en) 2011-06-07 2011-06-07 Method for enhancing training effectiveness
US13/154,933 2011-06-07

Publications (1)

Publication Number Publication Date
WO2012170596A1 true WO2012170596A1 (fr) 2012-12-13

Family

ID=47293493

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/041194 WO2012170596A1 (fr) 2011-06-07 2012-06-07 Procédé permettant d'augmenter l'efficacité d'entraînement

Country Status (2)

Country Link
US (1) US20120315614A1 (fr)
WO (1) WO2012170596A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2521841C1 (ru) * 2013-03-01 2014-07-10 Закрытое акционерное общество "Специальное конструкторское бюро экспериментального оборудования при Институте медико-биологических проблем Российской академии наук" Мобильный дыхательный тренажер для проведения гипоксически-гипероксических тренировок

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015009457A1 (de) * 2014-09-05 2016-03-10 Weinmann Geräte für Medizin GmbH + Co. KG Beatmungsgerät und Verfahren zur Steuerung einer Atemgasquelle
US11727826B2 (en) 2020-03-02 2023-08-15 Ryan Ziegler Resuscitation training device and method of use
US11712603B1 (en) 2022-12-07 2023-08-01 Telesair, Inc. Physical rehabilitation method and related products

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179958A (en) * 1988-06-29 1993-01-19 Mault James R Respiratory calorimeter with bidirectional flow monitor
US20030077330A1 (en) * 2000-09-06 2003-04-24 Rafael Rubianes Lopez Helium-oxygen mixture with therapeutic application
US6592848B1 (en) * 1999-07-02 2003-07-15 Air Liquide Sante (International) Mixtures of oxygen and helium for the treatment of respiratory insufficiency
US20080251079A1 (en) * 2007-04-13 2008-10-16 Invacare Corporation Apparatus and method for providing positive airway pressure

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0517990B1 (fr) * 1991-06-12 1999-03-10 Tradotec S.A. Dispositif ergométrique
US9675774B2 (en) * 2009-04-02 2017-06-13 Breathe Technologies, Inc. Methods, systems and devices for non-invasive open ventilation with gas delivery nozzles in free space

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179958A (en) * 1988-06-29 1993-01-19 Mault James R Respiratory calorimeter with bidirectional flow monitor
US6592848B1 (en) * 1999-07-02 2003-07-15 Air Liquide Sante (International) Mixtures of oxygen and helium for the treatment of respiratory insufficiency
US20030077330A1 (en) * 2000-09-06 2003-04-24 Rafael Rubianes Lopez Helium-oxygen mixture with therapeutic application
US20080251079A1 (en) * 2007-04-13 2008-10-16 Invacare Corporation Apparatus and method for providing positive airway pressure

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2521841C1 (ru) * 2013-03-01 2014-07-10 Закрытое акционерное общество "Специальное конструкторское бюро экспериментального оборудования при Институте медико-биологических проблем Российской академии наук" Мобильный дыхательный тренажер для проведения гипоксически-гипероксических тренировок

Also Published As

Publication number Publication date
US20120315614A1 (en) 2012-12-13

Similar Documents

Publication Publication Date Title
CN102245245B (zh) 可变流量氧疗
US6192884B1 (en) Method and apparatus for supplemental oxygen delivery
CN104822408B (zh) 具有辅助按压的自动呼吸机
US6871645B2 (en) Reduced-oxygen breathing device
US7210479B2 (en) Hyperoxic breathing system
US20140007870A1 (en) Device and method for supplying and dosing gas to a breathing person
CN214860181U (zh) 一种可穿戴呼吸康复无创通气系统
US20120315614A1 (en) Method for enhancing training effectiveness
CN201108661Y (zh) 双气囊正压氧气呼吸器
EP2379147B1 (fr) Thérapie respiratoire phasique
EP2268368A1 (fr) Appareil permettant un entraînement et une thérapie par hypoxie
US20130071824A1 (en) Method for enhancing training effectiveness
EP2780067B1 (fr) Circuit anesthésique à récyclage du gaz exhalé
US20060150977A1 (en) Respiratory assist device and method of providing respiratory assistance
Jiang et al. The principle of upper airway unidirectional flow facilitates breathing in humans
Lindholm et al. A portable device for intermittent oxygen supplementation during high-intensity exercise
CN212817931U (zh) 一种肺功能锻炼装置
Mathias Endurance training and the lungs
Dodd et al. A practical approach to oxygen therapy in cystic fibrosis
CN2638756Y (zh) 一种袖珍氧疗仪
Standley et al. Equipment for inhalation of oxygen and other gassess
Blakeman et al. Development of a Re-Breathing System for Mechanical Ventilators
RU2470682C2 (ru) Дыхательный аппарат (варианты)
CN2765629Y (zh) 医用吸氧装置
CZ2012438A3 (cs) Zařízení pro operativní manipulaci se vzduchem

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12796047

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12796047

Country of ref document: EP

Kind code of ref document: A1