WO2012158580A3 - Oral care composition for treating dry mouth - Google Patents

Oral care composition for treating dry mouth Download PDF

Info

Publication number
WO2012158580A3
WO2012158580A3 PCT/US2012/037687 US2012037687W WO2012158580A3 WO 2012158580 A3 WO2012158580 A3 WO 2012158580A3 US 2012037687 W US2012037687 W US 2012037687W WO 2012158580 A3 WO2012158580 A3 WO 2012158580A3
Authority
WO
WIPO (PCT)
Prior art keywords
dry mouth
oral care
care composition
treating dry
treating
Prior art date
Application number
PCT/US2012/037687
Other languages
French (fr)
Other versions
WO2012158580A2 (en
Inventor
Wei Wang
Harsh M. Trivedi
Mahmoud Hassan
Original Assignee
Colgate-Palmolive Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2014511431A priority Critical patent/JP2014513723A/en
Priority to SG2013075817A priority patent/SG194167A1/en
Priority to EP12723565.3A priority patent/EP2709586B1/en
Priority to BR112013029637A priority patent/BR112013029637A2/en
Priority to AU2012256033A priority patent/AU2012256033B2/en
Priority to CN201280023396.0A priority patent/CN103561719A/en
Priority to EP16182206.9A priority patent/EP3111924B1/en
Priority to CA2836469A priority patent/CA2836469A1/en
Application filed by Colgate-Palmolive Company filed Critical Colgate-Palmolive Company
Priority to MX2013013393A priority patent/MX338801B/en
Priority to US14/114,855 priority patent/US9675542B2/en
Priority to RU2013155617/15A priority patent/RU2013155617A/en
Publication of WO2012158580A2 publication Critical patent/WO2012158580A2/en
Publication of WO2012158580A3 publication Critical patent/WO2012158580A3/en
Priority to ZA2013/07932A priority patent/ZA201307932B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Described herein are oral compositions comprising an extract obtained from Arialaceae, Zingiberaceae, Lamiaceae, Fabaceae, Solanaceae, Punicaceae. Asteraceae or mixtures thereof; Their uses for alleviating dry mouth is also described.
PCT/US2012/037687 2011-05-16 2012-05-14 Oral care compositions WO2012158580A2 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
EP16182206.9A EP3111924B1 (en) 2011-05-16 2012-05-14 Oral care compositions
EP12723565.3A EP2709586B1 (en) 2011-05-16 2012-05-14 Oral care composition for treating dry mouth
BR112013029637A BR112013029637A2 (en) 2011-05-16 2012-05-14 oral care compositions
AU2012256033A AU2012256033B2 (en) 2011-05-16 2012-05-14 Oral care composition for treating dry mouth
CN201280023396.0A CN103561719A (en) 2011-05-16 2012-05-14 Oral care composition for treating dry mouth
JP2014511431A JP2014513723A (en) 2011-05-16 2012-05-14 Oral care composition
CA2836469A CA2836469A1 (en) 2011-05-16 2012-05-14 Oral care composition for treating dry mouth
SG2013075817A SG194167A1 (en) 2011-05-16 2012-05-14 Oral care composition for treating dry mouth
MX2013013393A MX338801B (en) 2011-05-16 2012-05-14 Oral care composition for treating dry mouth.
US14/114,855 US9675542B2 (en) 2011-05-16 2012-05-14 Oral care compositions
RU2013155617/15A RU2013155617A (en) 2011-05-16 2012-05-14 ORGANIC CARE COMPOSITIONS
ZA2013/07932A ZA201307932B (en) 2011-05-16 2013-10-23 Oral care composition for treating dry mouth

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US201161486349P 2011-05-16 2011-05-16
US201161486359P 2011-05-16 2011-05-16
US201161486371P 2011-05-16 2011-05-16
US201161486354P 2011-05-16 2011-05-16
US201161486366P 2011-05-16 2011-05-16
US201161486356P 2011-05-16 2011-05-16
US201161486352P 2011-05-16 2011-05-16
US61/486,356 2011-05-16
US61/486,354 2011-05-16
US61/486,359 2011-05-16
US61/486,366 2011-05-16
US61/486,349 2011-05-16
US61/486,352 2011-05-16
US61/486,371 2011-05-16

Publications (2)

Publication Number Publication Date
WO2012158580A2 WO2012158580A2 (en) 2012-11-22
WO2012158580A3 true WO2012158580A3 (en) 2013-01-10

Family

ID=46149732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/037687 WO2012158580A2 (en) 2011-05-16 2012-05-14 Oral care compositions

Country Status (14)

Country Link
US (1) US9675542B2 (en)
EP (2) EP3111924B1 (en)
JP (1) JP2014513723A (en)
CN (1) CN103561719A (en)
AR (1) AR086421A1 (en)
AU (2) AU2012256033B2 (en)
BR (1) BR112013029637A2 (en)
CA (1) CA2836469A1 (en)
CO (1) CO6801778A2 (en)
MX (2) MX338801B (en)
RU (1) RU2013155617A (en)
SG (1) SG194167A1 (en)
TW (1) TW201309338A (en)
WO (1) WO2012158580A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102940595A (en) * 2012-12-04 2013-02-27 中国科学院新疆理化技术研究所 Mouthwash with functions of antibiosis, antiphlogosis and deodorization, and preparation method and use thereof
EP2745836B1 (en) * 2012-12-18 2016-08-31 Sunstar Suisse SA Topical oral composition for alleviating dry mouth symptoms and for treating mouth ulcers
JP2014162750A (en) * 2013-02-25 2014-09-08 Kaigen Pharma Co Ltd Salivation-promoting compositions
CN110099681A (en) * 2016-10-04 2019-08-06 塞尔利克斯生物私人有限公司 For treating the composition and method of xerostomia
KR101843750B1 (en) * 2016-11-23 2018-04-05 주식회사 케이원 Orally disintegrating film for removing oral smell comprising wild ginseng concentrate and manufacturing method thereof
TW202038920A (en) * 2018-12-27 2020-11-01 日商花王股份有限公司 Effervescent oral solid preparation
JP7463058B2 (en) 2019-02-08 2024-04-08 アリナミン製薬株式会社 Compositions with ACE inhibitory activity

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002173425A (en) * 2000-12-07 2002-06-21 Kao Corp Throat care agent
US20030170322A1 (en) * 2000-06-21 2003-09-11 Shigeto Kayane Throat care agents
US20040126441A1 (en) * 2002-12-30 2004-07-01 Council Of Scientific And Industrial Development of an anti-cough, anti-tussive and throat soothing herbal formulation
JP2004359595A (en) * 2003-06-04 2004-12-24 Earth Chem Corp Ltd Liquid throat-protective composition
US20070297993A1 (en) * 2006-04-19 2007-12-27 Symrise Gmbh & Co. Kg Novel Use of Nonenolide
EP2039356A1 (en) * 2007-09-20 2009-03-25 Universite De Nice-Sophia Antipolis Sialagogue composition comprising a M3 muscarinic agonist and an alpha-2 adrenergic antagonist
CN101849979A (en) * 2009-11-06 2010-10-06 中山市中智药业集团有限公司 Chinese medicinal composition granules and preparation method thereof

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1438205A (en) 1974-08-27 1976-06-03 Lion Dentifrice Co Ltd Dentifrice composition
US5288480A (en) 1987-01-30 1994-02-22 Colgate-Palmolive Co. Antiplaque antibacterial oral composition
US4894220A (en) 1987-01-30 1990-01-16 Colgate-Palmolive Company Antibacterial antiplaque oral composition
GB9611364D0 (en) * 1996-05-31 1996-08-07 Smithkline Beecham Plc Composition
GB2317339A (en) 1996-08-01 1998-03-25 Procter & Gamble Dentifrice composition containing a curcuminoid
US6949264B1 (en) 1996-11-27 2005-09-27 Wm. Wrigley Jr. Company Nutraceuticals or nutritional supplements and method of making
US5980869A (en) 1997-04-28 1999-11-09 The Procter & Gamble Company Dual phase oral compositions comprising a plant extract from the Ericaceae family
AUPR520701A0 (en) 2001-05-23 2001-06-14 Liu, Xiaoming Herbal composition for the treatment of drug addiction
ES2186569B1 (en) 2001-09-28 2004-09-16 Lacer, S.A. COMPOSITIONS FOR THE RELIEF OF XEROSTOMY AND THE TREATMENT OF DISORDERS ASSOCIATED WITH THE SAME.
US6855346B2 (en) 2001-10-05 2005-02-15 Tzu-Sheng Wu Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same
US20060177384A1 (en) 2001-12-04 2006-08-10 Brown Dale G Sialagogue coatings for interproximal devices
FR2837709B1 (en) 2002-03-26 2005-05-13 Innovations Pharma Ag THERMOREVERSIBLE COMPOSITION FOR COMPENSATING THE HYPOSIALIES AND ASIALIES CAUSED BY XEROSTOMIES
EP1496851A1 (en) 2002-04-25 2005-01-19 Gaba International AG Oral care products containing ovomucin
DE60333196D1 (en) 2002-08-27 2010-08-12 Wrigley W M Jun Co AIRBORNE AND MOUTHPROOF PRODUCT USING CARDAMOM L
FR2848852B1 (en) 2002-12-23 2007-03-16 Carilene Lab OILY COMPOSITION BASED ON PEROXIDIC LIPIDS USEFUL IN THE TREATMENT OF XEROSTOMY
EP3143983A1 (en) 2003-02-13 2017-03-22 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo External dermatological formulation comprising saccharide derivative of alpha, alpha-trehalose
US20040180077A1 (en) 2003-03-05 2004-09-16 Riker Donald K. Rapidly dissolving edible strips for treating obesity
KR100700065B1 (en) 2004-04-20 2007-03-27 신준식 A composition of chinese drugs having neuro-protecting activity
EP1793799B1 (en) 2004-08-02 2010-05-05 Glaxo Group Limited Novel composition for treating xerostomia
US20060062859A1 (en) 2004-08-05 2006-03-23 Kenneth Blum Composition and method to optimize and customize nutritional supplement formulations by measuring genetic and metabolomic contributing factors to disease diagnosis, stratification, prognosis, metabolism, and therapeutic outcomes
US20060134235A1 (en) * 2004-12-22 2006-06-22 Toyo Shinyaku Co., Ltd. External preparation for improving blood flow
CA2608651A1 (en) 2005-05-24 2006-11-30 Wellgen, Inc. Compositions and methods for the prevention and treatment of conditions associated with inflammation
GB0513367D0 (en) 2005-06-30 2005-08-03 Glaxo Group Ltd Novel composition
ATE536916T1 (en) * 2005-10-14 2011-12-15 Symrise Ag SYNERGISTIC BLENDS OF BISABOLOL AND GINGER EXTRACT
WO2007092811A2 (en) 2006-02-07 2007-08-16 Whitehill Oral Technologies, Inc. Sialagogue based oral care products
EP2083633A4 (en) 2006-10-11 2012-01-18 Wrigley W M Jun Co Oral delivery vehicles containing a traditional chinese medicine of extract thereof
WO2008079898A1 (en) * 2006-12-20 2008-07-03 Pharmwest, Inc. Methods and topical formulations comprising colloidal metal for treating or preventing skin conditions
US8173711B2 (en) 2007-01-31 2012-05-08 Kaneka Corporation Agent for relief or prevention of xerostomia
ES2304103B1 (en) 2007-02-22 2009-08-07 Biocosmetics S.L. COMPOSITION FOR TREATMENT OF XEROSTOMY OR DRY MOUTH.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US8053004B2 (en) 2007-10-08 2011-11-08 Starmaker Products, Llc Ointment for topical treatment of hot flashes and method of use
GB0720516D0 (en) 2007-10-18 2007-11-28 Cadbury Schweppes Plc Comestible products
CN101970008B (en) 2008-03-10 2013-10-30 拜耳消费者保健股份公司 Palatable solid composition comprising antacid and saliva stimulant
US20100022471A1 (en) 2008-07-23 2010-01-28 Sage Products Inc. Oral Moisturizer for Alleviating Dry Mouth
US20110274728A1 (en) 2008-11-13 2011-11-10 David Hamlin Compositions and Methods for Alleviating Hyposalivation and for Providing Oral Comfort
EP2400841A1 (en) 2009-02-25 2012-01-04 Georgia Health Sciences University Research Institute, Inc. Oral care compositions for treating xerostomia
US20100278944A1 (en) 2009-05-04 2010-11-04 Naturex, S.A. Application of american ginseng to enhance neurocognitive function
MY160412A (en) * 2009-12-04 2017-03-15 Colgate Palmolive Co Oral compositions containing extracts of zingiber officinale and related methods

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170322A1 (en) * 2000-06-21 2003-09-11 Shigeto Kayane Throat care agents
JP2002173425A (en) * 2000-12-07 2002-06-21 Kao Corp Throat care agent
US20040126441A1 (en) * 2002-12-30 2004-07-01 Council Of Scientific And Industrial Development of an anti-cough, anti-tussive and throat soothing herbal formulation
JP2004359595A (en) * 2003-06-04 2004-12-24 Earth Chem Corp Ltd Liquid throat-protective composition
US20070297993A1 (en) * 2006-04-19 2007-12-27 Symrise Gmbh & Co. Kg Novel Use of Nonenolide
EP2039356A1 (en) * 2007-09-20 2009-03-25 Universite De Nice-Sophia Antipolis Sialagogue composition comprising a M3 muscarinic agonist and an alpha-2 adrenergic antagonist
CN101849979A (en) * 2009-11-06 2010-10-06 中山市中智药业集团有限公司 Chinese medicinal composition granules and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GNPD [online] MINTEL; June 2007 (2007-06-01), "Toothpaste", XP002682115, Database accession no. 728223 *
DATABASE GNPD [online] MINTEL; November 2009 (2009-11-01), "Energy and Breath Freshener", XP002682113, Database accession no. 1209441 *
DATABASE GNPD [online] MINTELm; April 2002 (2002-04-01), "Organic Mouthwash Spray", XP002682114, Database accession no. 10107001 *
J-W PARK ET ALL: "Effects of Korean Red Ginseng on Dry Mouth : A Randomized, Double-Blind, Placebo-Controlled Trial", JOURNAL OF GINSENG RESEARCH, vol. 34, no. 3, 2010, pages 183 - 191, XP002682112, Retrieved from the Internet <URL:http://www.oridoc.co.kr/file/97.pdf> [retrieved on 20120821] *

Also Published As

Publication number Publication date
US9675542B2 (en) 2017-06-13
EP3111924A3 (en) 2017-02-22
MX2013013393A (en) 2013-12-12
MX349990B (en) 2017-08-22
AU2012256033B2 (en) 2015-07-02
MX338801B (en) 2016-05-02
EP3111924B1 (en) 2019-07-10
AU2015234351A1 (en) 2015-10-29
CN103561719A (en) 2014-02-05
EP3111924A2 (en) 2017-01-04
BR112013029637A2 (en) 2019-09-24
RU2013155617A (en) 2015-06-27
CA2836469A1 (en) 2012-11-22
EP2709586A2 (en) 2014-03-26
JP2014513723A (en) 2014-06-05
TW201309338A (en) 2013-03-01
CO6801778A2 (en) 2013-11-29
SG194167A1 (en) 2013-12-30
AR086421A1 (en) 2013-12-11
EP2709586B1 (en) 2016-08-24
US20140065080A1 (en) 2014-03-06
AU2012256033A1 (en) 2013-05-02
WO2012158580A2 (en) 2012-11-22
AU2015234351B2 (en) 2017-03-09

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