WO2012131651A1 - Compositions à base de plantes pour augmenter et améliorer la production laitière d'un troupeau - Google Patents
Compositions à base de plantes pour augmenter et améliorer la production laitière d'un troupeau Download PDFInfo
- Publication number
- WO2012131651A1 WO2012131651A1 PCT/IB2012/051582 IB2012051582W WO2012131651A1 WO 2012131651 A1 WO2012131651 A1 WO 2012131651A1 IB 2012051582 W IB2012051582 W IB 2012051582W WO 2012131651 A1 WO2012131651 A1 WO 2012131651A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dioscorea bulbifera
- herbal compositions
- herbal
- bulbifera
- dioscorea
- Prior art date
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- the synthetic medicines or compositions, and associated enhancement methods can be effective in increasing milk yield, but they pose the threat of side effects and chemical toxicity which can adversely affect a subject's overall health, and mostly involve high cost and effort in manufacturing.
- the object of the invention is to provide novel herbal compositions which may be cost effective and easily available for increase and improvement of milk yield in a subject, and which have less or no side effects to the health of a subject.
- the present invention in a preferred embodiment provides herbal compositions for increase and improvement of milk yield in a subject, comprising of at least a part of Dioscorea bulbifera, to which parts of one or more additional complimentary herb may be optionally added, wherein the additional complimentary herb is also a herb for increase and improvement of milk yield in a subject and is selected from but not limited to Chenopodium ambrosioides seeds, Desmodium gangeticum leaves, Nigella sativa leaves, leaves, rice water, genera Centella, Withania, Asparagus, Chlorophytum, Boerhaavia, Sida, Saraca, Elettaria
- the invention also provides for methods of preparation of the herbal compositions.
- the present invention in a preferred embodiment provides herbal compositions for increase and improvement of milk yield in cattle, comprising of at least a part of Dioscorea bulbifera, to which parts of one or more additional complimentary herb may be optionally added, wherein the additional complimentary herb is also a herb for increase and improvement of milk yield in cattle and is selected from but not limited to Chenopodium ambrosioides seeds, Desmodium gangeticum leaves, Nigella sativa leaves, rice water, genera Centella, Withania, Asparagus, Chlorophytum, Boerhaavia, Sida, Saraca, Elettaria cardamomum, Piper longum, Myristica fragrans fruit, or any combination thereof.
- Parts of Dioscorea bulbifera for the purpose of this invention includes the whole Dioscorea bulbifera, extract of Dioscorea bulbifera, pulverized form of Dioscorea bulbifera, crushed form of Dioscorea bulbifera, pieces cut or severed from Dioscorea bulbifera, chemical constituents of Dioscorea bulbifera along with their derivatives, or any combination thereof.
- the parts of Dioscorea bulbifera are severed by different methods such as but not limited to cutting, slicing, pounding, grinding, mashing or mincing.
- composition' for the purpose of this invention means a substance or mixture comprising of at least one natural component having medicinal property, wherein the natural component shall include a component extracted or derived from a natural source such as a herb or a shrub or a tree or a plant or parts thereof.
- subject for the purpose of the invention means one or more of a human or any other animal which is capable of producing milk.
- a solvent may be used for preparing the herbal compositions of the present invention, and the solvent used may be any suitable solvent such as but not limited to one or more of methanol, ethanol, n-propanol, isopropanol, hexane, heptane, petroleum ether, cyclohexane, diethyl ether, dusopropyl ether, ethyl acetate, methyl acetate, ethyl formate, methyl formate, isobutyl acetate, n-butyl acetate, methylene chloride, ethylene chloride, chloroform, carbon tetrachloride, acetone, ethyl methyl ketone, diisobutyl ketone, methyl isobutyl ketone, 1,4- dioxan
- a suitable excipient is added to the herbal compositions of the present invention to prepare a consumable formulation for effective therapeutic delivery.
- the herbal compositions of the present invention may be formulated for oral administration by compounding the active ingredients with the usual nontoxic pharmaceutically acceptable excipients for tablets, pellets, granules, capsules, solutions, emulsions, suspensions, and any other form suitable for use.
- Formulations in accordance with the present invention may include one or more of talc, water, glucose, lactose, gum acacia, gelatin, mannitol, starch paste, magnesium trisilicate, corn starch, keratin, colloidal silica, potato starch, urea, and other excipients suitable for use in manufacturing preparations, in solid, semisolid or liquid form, or any combination thereof.
- auxiliary, stabilizing, thickening, flavoring, fragrance and coloring agents may be used.
- the herbal compositions can be administered in a solid form such as but not limited to tablets, capsules, pills, pellets, granules, boluses or powder.
- a solid form such as but not limited to tablets, capsules, pills, pellets, granules, boluses or powder.
- the herbal compositions may be mixed with a pharmaceutical excipient such as but not limited to corn starch, lactose, sucrose, sorbitol, talc, stearic acid, magnesium stearate, dicalcium phosphate or gums, along with other pharmaceutical diluents.
- the solid compositions may be further subdivided into unit dosage forms containing an effective amount of compositions of the present invention.
- the herbal compositions can be administered in a liquid form such as but not limited to aqueous solution, suitably flavored syrups, aqueous suspensions, oil suspensions, tinctures, tisanes, macerates and flavored emulsions with edible oils as well as elixirs or similar pharmaceutical carriers.
- the liquid form may include suitable dispersing or suspending agents for aqueous suspensions such as but not limited to tragacanth, acacia, alginate, dextran, sodium carboxymethyl cellulose, methylcellulose, polyvinylpyrrolidone or gelatin.
- Liquid preparations for oral administration may take the form of, for example, solutions, syrups or suspensions, or they may be presented as a dry product for reconstitution with water or other suitable vehicles before use.
- a process for preparing an herbal composition for increase and improvement of milk yield comprise the steps of,
- a process for preparing an herbal composition for increase and improvement of milk yield comprise the steps of,
- a process for preparing an herbal composition for increase and improvement of milk yield comprise the steps of,
- a process for preparing an herbal composition for increase and improvement of milk yield comprise the steps of,
- the herbal compositions may be delivered as a semi-solid form or gelatinous solid, such as but not limited to paste, jelly, gel or chutney.
- the herbal compositions may be delivered as a gaseous form or in form of aerosols which includes but not limited to spray, fumes, inhalers or mist.
- the herbal compositions may also be formulated for parenteral administration by injection, which includes but is not limited to, using conventional catheterization techniques or infusion.
- the herbal compositions may also be formulated for topical administration, in the form of solution, cream, gel, ointment, powder, paste, gum or lozenge, using techniques known to those skilled in the formulation field.
- topical administration includes delivery of the compositions to mucosal tissue of the mouth, nose and throat by, for example, spray or mist application.
- the herbal compositions as an active ingredient may be used alone or in combination with other therapeutic agents, for increase and improvement of milk yield in a subject.
- the herbal compositions of the present invention may be in the form of a decoction or may be prepared using a decoction process.
- the parts of Dioscorea bulbifera can be given chemical treatment or made to react with other chemical reagents to form mixtures or herbal compositions which are used for increase and improvement of milk yield in a subject.
- the desirable dose of the compositions may vary depending on the condition and the weight of the subject, severity, drug form, route and period of administration.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Birds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention, dans un mode de réalisation préféré, concerne des compositions à base de plantes pour augmenter et améliorer la production laitière chez un sujet. La présente invention concerne également les procédés de préparation et diverses formes d'administration desdites compositions. Lesdites compositions sont constituées au moins en partie de Dioscorea bulbifera.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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IN1027/MUM/2011 | 2011-03-31 | ||
IN1027MU2011 | 2011-03-31 |
Publications (1)
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WO2012131651A1 true WO2012131651A1 (fr) | 2012-10-04 |
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PCT/IB2012/051582 WO2012131651A1 (fr) | 2011-03-31 | 2012-03-31 | Compositions à base de plantes pour augmenter et améliorer la production laitière d'un troupeau |
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WO (1) | WO2012131651A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107041470A (zh) * | 2017-04-28 | 2017-08-15 | 陕西师范大学 | 一种促进奶牛泌乳的饲料及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08325159A (ja) * | 1995-03-27 | 1996-12-10 | Toru Akaha | 糖尿病治療薬及び機能性食品 |
-
2012
- 2012-03-31 WO PCT/IB2012/051582 patent/WO2012131651A1/fr active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08325159A (ja) * | 1995-03-27 | 1996-12-10 | Toru Akaha | 糖尿病治療薬及び機能性食品 |
Non-Patent Citations (3)
Title |
---|
DATABASE TKDL [Online] ANONYMUS: "ALUKA GUNA", XP002678319, Database accession no. RS15/576 * |
DATABASE TKDL [Online] ANONYMUS: "ASTAVARGA GUNA", XP002678320, Database accession no. RS15/44 * |
DATABASE TKDL [Online] ANONYMUS: "BRHAT CHAGALADI GHRTA", XP002678318, Database accession no. VK5/567 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107041470A (zh) * | 2017-04-28 | 2017-08-15 | 陕西师范大学 | 一种促进奶牛泌乳的饲料及其制备方法 |
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