WO2012128667A3 - Vaccine against transmissible gastroenteritis in pigs and method for using said vaccine - Google Patents

Vaccine against transmissible gastroenteritis in pigs and method for using said vaccine Download PDF

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Publication number
WO2012128667A3
WO2012128667A3 PCT/RU2012/000177 RU2012000177W WO2012128667A3 WO 2012128667 A3 WO2012128667 A3 WO 2012128667A3 RU 2012000177 W RU2012000177 W RU 2012000177W WO 2012128667 A3 WO2012128667 A3 WO 2012128667A3
Authority
WO
WIPO (PCT)
Prior art keywords
vaccine
transmissible gastroenteritis
pigs
brood
sows
Prior art date
Application number
PCT/RU2012/000177
Other languages
French (fr)
Russian (ru)
Other versions
WO2012128667A2 (en
Inventor
Владислав Николаевич ЛАСКАВЫЙ
Сергей Иванович ИВАНЕНКО
Original Assignee
Laskavy Vladislav Nikolaevich
Ivanenko Sergei Ivanovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laskavy Vladislav Nikolaevich, Ivanenko Sergei Ivanovich filed Critical Laskavy Vladislav Nikolaevich
Publication of WO2012128667A2 publication Critical patent/WO2012128667A2/en
Publication of WO2012128667A3 publication Critical patent/WO2012128667A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention relates to biotechnology and concerns the manufacturing and use of a vaccine for the specific prophylaxis of transmissible gastroenteritis in pigs. The invention is directed towards solving the problem of creating an effective avirulent live vaccine against transmissible gastroenteritis and an operationally simple method for using said vaccine, said vaccine and method being directed simultaneously towards activating cellular immunity in brood sows, which provides colostral protection of newborn sucking pigs, and activating humoral immunity in brood sows, which provides protection of said brood sows against infection. The vaccine against transmissible gastroenteritis in pigs comprises a virus material from the "BH-96" virus strain of transmissible gastroenteritis in pigs in a titre of 7.0-7.2 lg of TCD (Tissue Cytopathic Dose) 50/ml, and a physiological solution as filler, with the following ratio of components: 0.09-0.1% by weight of "ВН-96" strain virus material, with the remainder being the physiological solution. The method for using the vaccine against transmissible gastroenteritis consists in a single intramuscular immunization of pregnant brood sows 40-45 days before farrowing, in a dose of 4.5-5 ml to the head.
PCT/RU2012/000177 2011-03-21 2012-03-15 Vaccine against transmissible gastroenteritis in pigs and method for using said vaccine WO2012128667A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2011110618/10A RU2463073C1 (en) 2011-03-21 2011-03-21 Swine transmissible gastroenteritis vaccine and method for preparing it
RU2011110618 2011-03-21

Publications (2)

Publication Number Publication Date
WO2012128667A2 WO2012128667A2 (en) 2012-09-27
WO2012128667A3 true WO2012128667A3 (en) 2012-11-15

Family

ID=46879942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2012/000177 WO2012128667A2 (en) 2011-03-21 2012-03-15 Vaccine against transmissible gastroenteritis in pigs and method for using said vaccine

Country Status (2)

Country Link
RU (1) RU2463073C1 (en)
WO (1) WO2012128667A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2682320C1 (en) * 2018-05-07 2019-03-19 Владислав Николаевич Ласкавый Means for the prevention of viral infections

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028804A2 (en) * 1979-11-13 1981-05-20 Iowa State University Research Foundation, Inc. Vaccine and method for its preparation
RU2347585C1 (en) * 2007-11-22 2009-02-27 Федеральное государственное учреждение "Всероссийский государственный центр качества и стандартизации лекарственных средств для животных и кормов" (ФГУ "ВГНКИ") Vaccine against transmissible gastroenteritis of pigs
RU2399668C1 (en) * 2009-06-23 2010-09-20 Государственное научное учреждение Саратовская научно-исследовательская ветеринарная станция Российской академии сельскохозяйственных наук Swine transmissible gastroenteritis "t=-96" virus strain used for manufacturing of diagnostic and vaccine preparations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3519710A (en) * 1967-08-10 1970-07-07 Edmund P Bass Direct active modified live virus vaccine immunization against transmissible gastroenteritis in swine piglets at birth

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028804A2 (en) * 1979-11-13 1981-05-20 Iowa State University Research Foundation, Inc. Vaccine and method for its preparation
RU2347585C1 (en) * 2007-11-22 2009-02-27 Федеральное государственное учреждение "Всероссийский государственный центр качества и стандартизации лекарственных средств для животных и кормов" (ФГУ "ВГНКИ") Vaccine against transmissible gastroenteritis of pigs
RU2399668C1 (en) * 2009-06-23 2010-09-20 Государственное научное учреждение Саратовская научно-исследовательская ветеринарная станция Российской академии сельскохозяйственных наук Swine transmissible gastroenteritis "t=-96" virus strain used for manufacturing of diagnostic and vaccine preparations

Also Published As

Publication number Publication date
WO2012128667A2 (en) 2012-09-27
RU2463073C1 (en) 2012-10-10

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