WO2012120498A8 - Non-invasive thermal treatment monitoring - Google Patents

Non-invasive thermal treatment monitoring Download PDF

Info

Publication number
WO2012120498A8
WO2012120498A8 PCT/IL2012/000104 IL2012000104W WO2012120498A8 WO 2012120498 A8 WO2012120498 A8 WO 2012120498A8 IL 2012000104 W IL2012000104 W IL 2012000104W WO 2012120498 A8 WO2012120498 A8 WO 2012120498A8
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
monitoring
attenuation
thermal
changes
Prior art date
Application number
PCT/IL2012/000104
Other languages
French (fr)
Other versions
WO2012120498A1 (en
Inventor
Noam WEISS
Haim Azhari
Jacob Sosna
Original Assignee
Technion Research & Development Foundation Ltd.
Hadasit Medical Research Services And Development Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research & Development Foundation Ltd., Hadasit Medical Research Services And Development Ltd. filed Critical Technion Research & Development Foundation Ltd.
Publication of WO2012120498A1 publication Critical patent/WO2012120498A1/en
Publication of WO2012120498A8 publication Critical patent/WO2012120498A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00057—Light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/376—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Optics & Photonics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

A method for thermal monitoring of HIFU and other thermal treatments, utilizing electro-magnetic radiation signal detection or image processing. The images or detectors output signals show the attenuation at the target tissue, and changes in the attenuation level may be correlated to changes in the tissue temperature and condition during treatment and the subsequent cooling down period. Additionally, the point at which denaturation and coagulation of the tissue occurs can be determined. Analysis of the functional change in attenuation with time of treatment enables the accumulated tissue damage to be quantified. The advantage of this method is that it indicates the level of damage in the tissue directly, instead of displaying tissue temperatures only. The method provides a cost effective non-invasive method for thermal monitoring during ablation, as an alternative to MRI monitoring or to CT monitoring based on temperature determination.
PCT/IL2012/000104 2011-03-04 2012-03-04 Non-invasive thermal treatment monitoring WO2012120498A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161457346P 2011-03-04 2011-03-04
US61/457,346 2011-03-04

Publications (2)

Publication Number Publication Date
WO2012120498A1 WO2012120498A1 (en) 2012-09-13
WO2012120498A8 true WO2012120498A8 (en) 2012-11-29

Family

ID=46797556

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2012/000104 WO2012120498A1 (en) 2011-03-04 2012-03-04 Non-invasive thermal treatment monitoring

Country Status (1)

Country Link
WO (1) WO2012120498A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103829967B (en) * 2012-11-28 2016-06-01 上海西门子医疗器械有限公司 Estimate device and method, the method determining interest district and the CT equipment in temperature field
KR20170107428A (en) 2014-11-19 2017-09-25 어드밴스드 카디악 테라퓨틱스, 인크. Ablation devices, systems and methods of using a high-resolution electrode assembly
WO2016081611A1 (en) 2014-11-19 2016-05-26 Advanced Cardiac Therapeutics, Inc. High-resolution mapping of tissue with pacing
WO2016081606A1 (en) 2014-11-19 2016-05-26 Advanced Cardiac Therapeutics, Inc. Systems and methods for high-resolution mapping of tissue
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
SG11201807618QA (en) 2016-03-15 2018-10-30 Epix Therapeutics Inc Improved devices, systems and methods for irrigated ablation
EP3614946B1 (en) 2017-04-27 2024-03-20 EPiX Therapeutics, Inc. Determining nature of contact between catheter tip and tissue
DE102019121366A1 (en) * 2019-08-07 2021-02-11 Aesculap Ag Apparatus and method for measuring tissue temperature
DE102019121375A1 (en) * 2019-08-07 2021-02-25 Aesculap Ag Device and method for determining a switch-off time of a medical instrument

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080039746A1 (en) * 2006-05-25 2008-02-14 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
US8556888B2 (en) * 2006-08-04 2013-10-15 INTIO, Inc. Methods and apparatuses for performing and monitoring thermal ablation
US8102964B2 (en) * 2008-09-29 2012-01-24 Mir Medical Imaging Research Holding Gmbh Breast locating device including an RFID transponder for a diagnostic instrument for examining a female breast

Also Published As

Publication number Publication date
WO2012120498A1 (en) 2012-09-13

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