WO2012104874A3 - Aqueous concentrated formulation of linezolid - Google Patents

Aqueous concentrated formulation of linezolid Download PDF

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Publication number
WO2012104874A3
WO2012104874A3 PCT/IN2012/000080 IN2012000080W WO2012104874A3 WO 2012104874 A3 WO2012104874 A3 WO 2012104874A3 IN 2012000080 W IN2012000080 W IN 2012000080W WO 2012104874 A3 WO2012104874 A3 WO 2012104874A3
Authority
WO
WIPO (PCT)
Prior art keywords
linezolid
aqueous concentrated
concentrated formulation
formulation
aqueous
Prior art date
Application number
PCT/IN2012/000080
Other languages
French (fr)
Other versions
WO2012104874A2 (en
Inventor
Suraj VELHAL
Harish CHINNARI
Subhash Gore
Manoj Pananchukunnath
Rajesh Gupta
Indu Bhushan
Original Assignee
Mylan Laboratories Limited.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mylan Laboratories Limited. filed Critical Mylan Laboratories Limited.
Publication of WO2012104874A2 publication Critical patent/WO2012104874A2/en
Publication of WO2012104874A3 publication Critical patent/WO2012104874A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Disclosed is the aqueous concentrated formulation of linezolid, more particularly, the aqueous concentrated formulation of linezolid comprising at least one solubilizer, wherein the formulation is preferably administered intravenously.
PCT/IN2012/000080 2011-02-02 2012-02-02 Aqueous concentrated formulation of linezolid WO2012104874A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN307/CHE/2011 2011-02-02
IN307CH2011 2011-02-02

Publications (2)

Publication Number Publication Date
WO2012104874A2 WO2012104874A2 (en) 2012-08-09
WO2012104874A3 true WO2012104874A3 (en) 2012-11-01

Family

ID=46603173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000080 WO2012104874A2 (en) 2011-02-02 2012-02-02 Aqueous concentrated formulation of linezolid

Country Status (1)

Country Link
WO (1) WO2012104874A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173949B (en) * 2014-09-12 2017-04-05 大理药业股份有限公司 A kind of XINGNAOJING ZHUSHEYE and preparation method thereof
CN106491528B (en) * 2016-12-02 2019-09-24 江苏豪森药业集团有限公司 Linezolid Injection and preparation method thereof
CN111920772A (en) * 2020-09-04 2020-11-13 浙江普利药业有限公司 Linezolid dry suspension and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1130379A (en) * 1993-09-09 1996-09-04 厄普约翰公司 Substituted oxazine and thiazine oxazolidinone antimicrobials
WO2002030395A1 (en) * 2000-10-10 2002-04-18 Pharmacia & Upjohn Company Topical antibiotic composition for treatment of eye infection
CN1713924A (en) * 2000-08-22 2005-12-28 法马西亚公司 Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading
CN101948442A (en) * 2009-07-10 2011-01-19 符健 Preparation method of linezolid and preparation thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1130379A (en) * 1993-09-09 1996-09-04 厄普约翰公司 Substituted oxazine and thiazine oxazolidinone antimicrobials
CN1713924A (en) * 2000-08-22 2005-12-28 法马西亚公司 Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading
WO2002030395A1 (en) * 2000-10-10 2002-04-18 Pharmacia & Upjohn Company Topical antibiotic composition for treatment of eye infection
CN101948442A (en) * 2009-07-10 2011-01-19 符健 Preparation method of linezolid and preparation thereof

Also Published As

Publication number Publication date
WO2012104874A2 (en) 2012-08-09

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