WO2012102584A3 - 표적 바이러스 검출용 센서 및 이를 이용한 표적 바이러스 스크리닝 및 돌연변이 위치 분석 방법 - Google Patents

표적 바이러스 검출용 센서 및 이를 이용한 표적 바이러스 스크리닝 및 돌연변이 위치 분석 방법 Download PDF

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Publication number
WO2012102584A3
WO2012102584A3 PCT/KR2012/000655 KR2012000655W WO2012102584A3 WO 2012102584 A3 WO2012102584 A3 WO 2012102584A3 KR 2012000655 W KR2012000655 W KR 2012000655W WO 2012102584 A3 WO2012102584 A3 WO 2012102584A3
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WIPO (PCT)
Prior art keywords
target virus
sensor
virus
mutation location
same
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PCT/KR2012/000655
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English (en)
French (fr)
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WO2012102584A9 (ko
WO2012102584A2 (ko
Inventor
이정훈
차미선
오흥범
박주성
최준규
박진혁
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서울대학교 산학협력단
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Publication of WO2012102584A2 publication Critical patent/WO2012102584A2/ko
Publication of WO2012102584A9 publication Critical patent/WO2012102584A9/ko
Publication of WO2012102584A3 publication Critical patent/WO2012102584A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

본원 발명은 표적 바이러스 검출 및 돌연변이 위치를 분석할 수 있는 센서 및 검출 방법에 대한 것이다. 보다 구체적으로 표적 바이러스의 돌연변이 예상 위치가 5'의 최종 말단, 내부 또는 3'의 최종 말단에 위치한 프루브를 포함한, 나노계면트랜스듀서로 구성된 표적 바이러스 검출용 센서 및 이를 이용하여, 정전 용량의 변화를 이용하여, 표적 바이러스의 유무를 스크리닝 하는 방법 및 돌연변이의 위치를 분석하는 방법에 대한 것이다. 본원 발명은 바이러스 검출 및 바이러스의 유전자형을 동시에 검출할 수 있다.
PCT/KR2012/000655 2011-01-28 2012-01-30 표적 바이러스 검출용 센서 및 이를 이용한 표적 바이러스 스크리닝 및 돌연변이 위치 분석 방법 WO2012102584A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110008965A KR20120087637A (ko) 2011-01-28 2011-01-28 표적 바이러스 검출용 센서 및 이를 이용한 표적 바이러스 스크리닝 및 돌연변이 위치 분석 방법
KR10-2011-0008965 2011-01-28

Publications (3)

Publication Number Publication Date
WO2012102584A2 WO2012102584A2 (ko) 2012-08-02
WO2012102584A9 WO2012102584A9 (ko) 2012-11-01
WO2012102584A3 true WO2012102584A3 (ko) 2012-12-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/000655 WO2012102584A2 (ko) 2011-01-28 2012-01-30 표적 바이러스 검출용 센서 및 이를 이용한 표적 바이러스 스크리닝 및 돌연변이 위치 분석 방법

Country Status (2)

Country Link
KR (1) KR20120087637A (ko)
WO (1) WO2012102584A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10564123B2 (en) 2014-05-25 2020-02-18 United Arab Emirates University Bioreactor system and method of operating same for cellular composition identification and quantification
US10436772B2 (en) 2014-08-25 2019-10-08 United Arab Emirates University Method and system for counting white blood cells electrically

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100438822B1 (ko) * 2001-05-29 2004-07-05 삼성전자주식회사 핵산 돌연변이 분석 장치 및 그를 이용한 핵산 분석 방법
KR20070122012A (ko) * 2006-06-23 2007-12-28 대전보건대학 산학협력단 생체 정보 인식 및 분석을 통한 진단시스템 및 그 방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100438822B1 (ko) * 2001-05-29 2004-07-05 삼성전자주식회사 핵산 돌연변이 분석 장치 및 그를 이용한 핵산 분석 방법
KR20070122012A (ko) * 2006-06-23 2007-12-28 대전보건대학 산학협력단 생체 정보 인식 및 분석을 통한 진단시스템 및 그 방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHA, M. ET AL.: "Biomolecular detection with a thin membrane transducer", LAB CHIP, vol. 8, no. 6, June 2008 (2008-06-01), pages 932 - 937 *
CHO, JUN-KYU ET AL.: "Biomolecular detection with thin membrane transducer", THE KOREAN SOCIETY OF MECHANICAL ENGINEERS AUTUMN CONFERENCE, 2009 *

Also Published As

Publication number Publication date
KR20120087637A (ko) 2012-08-07
WO2012102584A9 (ko) 2012-11-01
WO2012102584A2 (ko) 2012-08-02

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