WO2012094114A3 - Systèmes et procédés de cryostockage de micro-échantillons - Google Patents

Systèmes et procédés de cryostockage de micro-échantillons Download PDF

Info

Publication number
WO2012094114A3
WO2012094114A3 PCT/US2011/064877 US2011064877W WO2012094114A3 WO 2012094114 A3 WO2012094114 A3 WO 2012094114A3 US 2011064877 W US2011064877 W US 2011064877W WO 2012094114 A3 WO2012094114 A3 WO 2012094114A3
Authority
WO
WIPO (PCT)
Prior art keywords
cryostorage
microsample
systems
methods
vial assembly
Prior art date
Application number
PCT/US2011/064877
Other languages
English (en)
Other versions
WO2012094114A2 (fr
Inventor
David A. Barrow
Original Assignee
The University Of North Carolina At Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of North Carolina At Chapel Hill filed Critical The University Of North Carolina At Chapel Hill
Priority to US13/977,878 priority Critical patent/US20140014550A1/en
Publication of WO2012094114A2 publication Critical patent/WO2012094114A2/fr
Publication of WO2012094114A3 publication Critical patent/WO2012094114A3/fr

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/04Partitions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0242Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0252Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
    • A01N1/0257Stationary or portable vessels generating cryogenic temperatures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50855Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/50Cryostats
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/028Modular arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/021Identification, e.g. bar codes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0851Bottom walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56Labware specially adapted for transferring fluids
    • B01L3/563Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
    • B01L3/5635Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors connecting two containers face to face, e.g. comprising a filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42Low-temperature sample treatment, e.g. cryofixation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00792Type of components bearing the codes, other than sample carriers
    • G01N2035/00801Holders for sample carriers, e.g. trays, caroussel, racks

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Biochemistry (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

La présente invention concerne un ensemble à plusieurs fioles, destiné à contenir une pluralité d'échantillons dans un système de cryostockage. Ledit système comprend une pluralité de fioles, qui définissent chacune une chambre de fiole destinée à contenir un échantillon respectif, et qui sont couplées pour former un ensemble fioles intégré. Lesdites fioles sont indépendamment amovibles de l'ensemble fioles intégré, permettant ainsi l'accès sélectif aux échantillons respectifs.
PCT/US2011/064877 2011-01-06 2011-12-14 Systèmes et procédés de cryostockage de micro-échantillons WO2012094114A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/977,878 US20140014550A1 (en) 2011-01-06 2011-12-14 Microsample cryostorage systems and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161430292P 2011-01-06 2011-01-06
US61/430,292 2011-01-06

Publications (2)

Publication Number Publication Date
WO2012094114A2 WO2012094114A2 (fr) 2012-07-12
WO2012094114A3 true WO2012094114A3 (fr) 2012-08-30

Family

ID=46457916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/064877 WO2012094114A2 (fr) 2011-01-06 2011-12-14 Systèmes et procédés de cryostockage de micro-échantillons

Country Status (2)

Country Link
US (1) US20140014550A1 (fr)
WO (1) WO2012094114A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8955696B2 (en) 2012-06-08 2015-02-17 Tina Ting-Yuan Wang Storage systems for milk bags
DE102013107101A1 (de) * 2013-07-05 2015-01-08 Netzsch-Gerätebau GmbH Verfahren und magazin zum vorhalten, transport, verarbeiten und archivieren von thermoanalytischer proben
CN112108194A (zh) * 2014-01-14 2020-12-22 拉伯赛特股份有限公司 带有识别标记的样本容器
US9861987B2 (en) 2014-01-15 2018-01-09 Labcyte Inc. Roughly cylindrical sample containers having multiple reservoirs therein and being adapted for acoustic ejections
US20160153703A1 (en) * 2014-08-14 2016-06-02 Sharon Jones Freezer Rack
WO2016178635A1 (fr) * 2015-05-06 2016-11-10 National University Hospital (Singapore) Pte Ltd Flacons pour le stockage d'échantillons biologiques
CN109229712B (zh) * 2018-07-09 2020-12-29 钟丽菊 一种食物储存设备

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004978A1 (fr) * 1990-09-26 1992-04-02 Cryo-Cell International, Inc. Procede de preparation d'echantillons biologiques et receptacle de stockage associe
US5417329A (en) * 1991-09-04 1995-05-23 Whitman; Robert S. Vertical storage and dispensing means
US6286678B1 (en) * 1999-03-05 2001-09-11 Rainin Instruments Co., Inc. Refill pack for pipette tip racks and improved pipette tip support plate for use in such packs and racks
US6564120B1 (en) * 2000-05-11 2003-05-13 Cryo-Cell International, Inc. Storage system, particularly with automatic insertion and retrieval
US20060196193A1 (en) * 2005-02-25 2006-09-07 Byrne Kathleen H Multi-purpose containment apparatus for controlled rate freezing and long term cryogenic storage, and method of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1354286A (en) * 1970-05-13 1974-05-22 Bagshawe K D Performance of routine chemical reactions
US7350703B2 (en) * 2004-04-23 2008-04-01 Ambartsoumian Gourgen Low temperature radio frequency identification tracking system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004978A1 (fr) * 1990-09-26 1992-04-02 Cryo-Cell International, Inc. Procede de preparation d'echantillons biologiques et receptacle de stockage associe
US5417329A (en) * 1991-09-04 1995-05-23 Whitman; Robert S. Vertical storage and dispensing means
US6286678B1 (en) * 1999-03-05 2001-09-11 Rainin Instruments Co., Inc. Refill pack for pipette tip racks and improved pipette tip support plate for use in such packs and racks
US6564120B1 (en) * 2000-05-11 2003-05-13 Cryo-Cell International, Inc. Storage system, particularly with automatic insertion and retrieval
US20060196193A1 (en) * 2005-02-25 2006-09-07 Byrne Kathleen H Multi-purpose containment apparatus for controlled rate freezing and long term cryogenic storage, and method of use

Also Published As

Publication number Publication date
US20140014550A1 (en) 2014-01-16
WO2012094114A2 (fr) 2012-07-12

Similar Documents

Publication Publication Date Title
WO2012094114A3 (fr) Systèmes et procédés de cryostockage de micro-échantillons
EP3529357A4 (fr) Procédés et systèmes de codage de molécules d'acide nucléique provenant de cellules individuelles ou de populations de cellules
MX2018006430A (es) Preparacion de muestras de acido nucleico.
SG10201811714UA (en) Substance sealing method and target molecule detecting method
WO2015200893A3 (fr) Procédés d'analyse d'acides nucléiques provenant de cellules individuelles ou de populations de cellules
WO2016172454A8 (fr) Structure cellulaire microfluidique
EP3253491A4 (fr) Système et procédé pour analyse génétique sur cellule unique
EP4286516A3 (fr) Procédés et systèmes de traitement de cloisonnement
EA201391245A1 (ru) Интеррогативные клеточные анализы и их применение
MX344792B (es) Sistemas y métodos para múltiples análisis.
SG10201912283RA (en) Nucleic acid sequence analysis from single cells
EP3372666A4 (fr) Dispositif et système microfluidique pour l'étude de cultures cellulaires
CA2931582C (fr) Cartouche microfluidique destinee au diagnostic moleculaire, station d'accueil employant ladite cartouche microfluidique et procede d'analyse d'un prelevement biologique
WO2013151577A8 (fr) Dosages exploratoires à base de cellules et utilisations de ceux-ci
WO2011094572A3 (fr) Dispositifs, systèmes et/ou procédés pour cultures en gouttes suspendues
EP3194560A4 (fr) Système microfluidique et procédé de rétention de cellules destinées à un bioréacteur à perfusion
Chan et al. Chemical synthesis and biological evaluation of the englerin analogues
EP3105326A4 (fr) Dispositif de préparation de banque d'acides nucléiques médiée par des cellules à liquides composites (clc), et ses procédés d'utilisation
EP3353280A4 (fr) Analyse d'étiquette de masse pour cellules rares et molécules sans cellules
EP3201350A4 (fr) Procédé pour l'analyse d'acide nucléique directement à partir d'un échantillon biologique non purifié
EP3302804A4 (fr) Porte-échantillon et système de dosage permettant de provoquer des réactions indiquées
WO2013111016A3 (fr) Isolement de biomolécules
WO2011121454A3 (fr) Analyse directe des acides nucléiques
EP2992114A4 (fr) Enrichissement de bibliotheques de sequençage d'adn a partir d'echantillons contenant de faibles quantites d'adn cible
WO2013028643A8 (fr) Préparation de polynucléotides sur un substrat solide pour effectuer un séquençage

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11854650

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 13977878

Country of ref document: US

122 Ep: pct application non-entry in european phase

Ref document number: 11854650

Country of ref document: EP

Kind code of ref document: A2