WO2012088276A3 - Fabrication de phospholipides et manipulation de composition par manipulation de milieu - Google Patents

Fabrication de phospholipides et manipulation de composition par manipulation de milieu Download PDF

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Publication number
WO2012088276A3
WO2012088276A3 PCT/US2011/066499 US2011066499W WO2012088276A3 WO 2012088276 A3 WO2012088276 A3 WO 2012088276A3 US 2011066499 W US2011066499 W US 2011066499W WO 2012088276 A3 WO2012088276 A3 WO 2012088276A3
Authority
WO
WIPO (PCT)
Prior art keywords
manipulation
additions
enzymes
composition
biochemical
Prior art date
Application number
PCT/US2011/066499
Other languages
English (en)
Other versions
WO2012088276A2 (fr
Inventor
Joseph Miller
John R. Palmer
Original Assignee
J3H, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J3H, Inc filed Critical J3H, Inc
Publication of WO2012088276A2 publication Critical patent/WO2012088276A2/fr
Publication of WO2012088276A3 publication Critical patent/WO2012088276A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6481—Phosphoglycerides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • A23D9/013—Other fatty acid esters, e.g. phosphatides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne un procédé de fabrication de phospholipides par la culture de microorganismes, dans un milieu de fermentation qui a été manipulé par des ajouts chimiques, biochimiques et enzymatiques. Les ajouts chimiques peuvent comprendre un ajout d'azote pour aider à déplacer une production d'huile microbienne vers des phospholipides. Les ajouts biochimiques comprennent des acides aminés spécifiques et les ajouts d'enzymes comprennent des enzymes transférases, des enzymes estérases et des enzymes phosphodiestérases spécifiques. Les microorganismes peuvent être des microalgues, de la levure, des bactéries ou des champignons.
PCT/US2011/066499 2010-12-21 2011-12-21 Fabrication de phospholipides et manipulation de composition par manipulation de milieu WO2012088276A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201061425366P 2010-12-21 2010-12-21
US61/425,366 2010-12-21

Publications (2)

Publication Number Publication Date
WO2012088276A2 WO2012088276A2 (fr) 2012-06-28
WO2012088276A3 true WO2012088276A3 (fr) 2012-11-29

Family

ID=46314888

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/066499 WO2012088276A2 (fr) 2010-12-21 2011-12-21 Fabrication de phospholipides et manipulation de composition par manipulation de milieu

Country Status (1)

Country Link
WO (1) WO2012088276A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019227034A1 (fr) 2018-05-25 2019-11-28 Locus Ip Company, Llc Compositions thérapeutiques permettant la cicatrisation améliorée de plaies et de cicatrices
WO2020185858A1 (fr) * 2019-03-12 2020-09-17 Locus Ip Company, Llc Matériaux et procédés de production de phospholipides du type cardiolipines
CN115975823B (zh) * 2022-08-17 2024-07-30 厦门大学 敲除磷脂酶d基因的裂殖壶菌基因工程菌株及其构建方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039758A1 (en) * 1997-02-20 2002-04-04 De Laat Wilhelmus Theodorus Antonius Maria Fermentative production of valuable compounds on an industrial scale using chemically defined media
US20070004014A1 (en) * 2005-06-29 2007-01-04 Yuichiro Tsuji Method for producing l-threonine
US20090004219A1 (en) * 2005-12-29 2009-01-01 Abl Biotechnologies Ltd. Novel Strain of Schizochytrium limacinum useful in the production of lipids and Extracellular Polysaccharides and process thereof
US20100162620A1 (en) * 2008-12-19 2010-07-01 Mccaffrey William Optimization of Algal Product Production through Uncoupling Cell Proliferation and Algal Product Production

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039758A1 (en) * 1997-02-20 2002-04-04 De Laat Wilhelmus Theodorus Antonius Maria Fermentative production of valuable compounds on an industrial scale using chemically defined media
US20070004014A1 (en) * 2005-06-29 2007-01-04 Yuichiro Tsuji Method for producing l-threonine
US20090004219A1 (en) * 2005-12-29 2009-01-01 Abl Biotechnologies Ltd. Novel Strain of Schizochytrium limacinum useful in the production of lipids and Extracellular Polysaccharides and process thereof
US20100162620A1 (en) * 2008-12-19 2010-07-01 Mccaffrey William Optimization of Algal Product Production through Uncoupling Cell Proliferation and Algal Product Production

Also Published As

Publication number Publication date
WO2012088276A2 (fr) 2012-06-28

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