WO2012077968A3 - Formulation complexe contenant de l'hydrochlorure de lercanidipine et du valsartan et son procédé de préparation - Google Patents
Formulation complexe contenant de l'hydrochlorure de lercanidipine et du valsartan et son procédé de préparation Download PDFInfo
- Publication number
- WO2012077968A3 WO2012077968A3 PCT/KR2011/009413 KR2011009413W WO2012077968A3 WO 2012077968 A3 WO2012077968 A3 WO 2012077968A3 KR 2011009413 W KR2011009413 W KR 2011009413W WO 2012077968 A3 WO2012077968 A3 WO 2012077968A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- valsartan
- lercanidipine hydrochloride
- preparation
- present
- complex formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA201390844A EA201390844A1 (ru) | 2010-12-09 | 2011-12-07 | Комплексный состав, содержащий гидрохлорид лерканидипина и валсартан, и способ его получения |
SG2013038211A SG190326A1 (en) | 2010-12-09 | 2011-12-07 | Complex formulation comprising lercanidipine hydrochloride and valsartan and method for the preparation thereof |
MX2013005716A MX2013005716A (es) | 2010-12-09 | 2011-12-07 | Formulacion de un complejo que comprende clorhidrato de lercanidipina y valsartan y metodo para la preparacion de la misma. |
BR112013013415A BR112013013415A2 (pt) | 2010-12-09 | 2011-12-07 | composição farmacêutica, e, método para a preparação de uma composição |
CN201180058951.9A CN103249415B (zh) | 2010-12-09 | 2011-12-07 | 包含盐酸乐卡地平和缬沙坦的复合制剂及其制备方法 |
UAA201307936A UA108277C2 (ru) | 2010-12-09 | 2011-12-07 | Комплексный препарат, содержащий лерканидипина гидрохлорид и валсартан, и способ его получения |
AU2011339150A AU2011339150B2 (en) | 2010-12-09 | 2011-12-07 | Complex formulation comprising lercanidipine hydrochloride and valsartan and method for the preparation thereof |
EP11847739.7A EP2648730A4 (fr) | 2010-12-09 | 2011-12-07 | Formulation complexe contenant de l'hydrochlorure de lercanidipine et du valsartan et son procédé de préparation |
TNP2013000212A TN2013000212A1 (en) | 2011-12-07 | 2013-05-15 | Complex formulation comprising lercanidipine hydrochloride and valsartan and mathod for the preparation therof |
IL226449A IL226449A0 (en) | 2010-12-09 | 2013-05-20 | A complex formulation containing larcanidipin |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2010-0125804 | 2010-12-09 | ||
KR20100125804 | 2010-12-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012077968A2 WO2012077968A2 (fr) | 2012-06-14 |
WO2012077968A3 true WO2012077968A3 (fr) | 2012-07-26 |
Family
ID=46207595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2011/009413 WO2012077968A2 (fr) | 2010-12-09 | 2011-12-07 | Formulation complexe contenant de l'hydrochlorure de lercanidipine et du valsartan et son procédé de préparation |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP2648730A4 (fr) |
KR (1) | KR101414814B1 (fr) |
CN (1) | CN103249415B (fr) |
AR (1) | AR084195A1 (fr) |
AU (1) | AU2011339150B2 (fr) |
BR (1) | BR112013013415A2 (fr) |
CL (1) | CL2013001626A1 (fr) |
CO (1) | CO6721030A2 (fr) |
DO (1) | DOP2013000115A (fr) |
EA (1) | EA201390844A1 (fr) |
IL (1) | IL226449A0 (fr) |
MX (1) | MX2013005716A (fr) |
PE (1) | PE20140699A1 (fr) |
SG (1) | SG190326A1 (fr) |
UA (1) | UA108277C2 (fr) |
UY (1) | UY33772A (fr) |
WO (1) | WO2012077968A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102755322B (zh) * | 2012-07-24 | 2013-12-11 | 兆科药业(广州)有限公司 | 一种乐卡地平和阿托伐他汀复方制剂 |
CN105163734A (zh) * | 2013-03-12 | 2015-12-16 | 株式会社Lg生命科学 | 包含缬沙坦及罗舒伐他汀钙的复合制剂及其制造方法 |
WO2019008485A1 (fr) | 2017-07-06 | 2019-01-10 | Mankind Pharma Ltd | Composition pharmaceutique à dose fixe à base de valsartan et de sacubitril |
KR102233986B1 (ko) * | 2019-06-25 | 2021-03-30 | 경남과학기술대학교 산학협력단 | 라푸티딘 및 이르소글라딘을 함유하는 고형 약제학적 조성물 및 이의 제조방법 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040198789A1 (en) * | 2003-02-28 | 2004-10-07 | Recordati Ireland Limited | Lercanidipine/ARB/diuretic therapeutic combinations |
US20070105912A1 (en) * | 2003-12-01 | 2007-05-10 | Per Holm | Pharmaceutical compositions comprising lercanidipine |
US20100047341A1 (en) * | 2006-10-10 | 2010-02-25 | Hanall Pharmaceutical Co., Ltd. | Combined preparation for the treatment of cardiovascular diseases based on chronotherapy theory |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5110697B2 (ja) | 2005-06-27 | 2012-12-26 | 第一三共株式会社 | 固形製剤 |
-
2011
- 2011-12-06 UY UY0001033772A patent/UY33772A/es not_active Application Discontinuation
- 2011-12-07 CN CN201180058951.9A patent/CN103249415B/zh active Active
- 2011-12-07 PE PE2013001346A patent/PE20140699A1/es not_active Application Discontinuation
- 2011-12-07 AR ARP110104583A patent/AR084195A1/es unknown
- 2011-12-07 SG SG2013038211A patent/SG190326A1/en unknown
- 2011-12-07 UA UAA201307936A patent/UA108277C2/ru unknown
- 2011-12-07 EA EA201390844A patent/EA201390844A1/ru unknown
- 2011-12-07 EP EP11847739.7A patent/EP2648730A4/fr not_active Withdrawn
- 2011-12-07 AU AU2011339150A patent/AU2011339150B2/en active Active
- 2011-12-07 KR KR1020110130400A patent/KR101414814B1/ko active IP Right Grant
- 2011-12-07 WO PCT/KR2011/009413 patent/WO2012077968A2/fr active Application Filing
- 2011-12-07 BR BR112013013415A patent/BR112013013415A2/pt not_active IP Right Cessation
- 2011-12-07 MX MX2013005716A patent/MX2013005716A/es unknown
-
2013
- 2013-05-20 IL IL226449A patent/IL226449A0/en unknown
- 2013-05-21 DO DO2013000115A patent/DOP2013000115A/es unknown
- 2013-06-06 CL CL2013001626A patent/CL2013001626A1/es unknown
- 2013-06-21 CO CO13147794A patent/CO6721030A2/es unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040198789A1 (en) * | 2003-02-28 | 2004-10-07 | Recordati Ireland Limited | Lercanidipine/ARB/diuretic therapeutic combinations |
US20070105912A1 (en) * | 2003-12-01 | 2007-05-10 | Per Holm | Pharmaceutical compositions comprising lercanidipine |
US20100047341A1 (en) * | 2006-10-10 | 2010-02-25 | Hanall Pharmaceutical Co., Ltd. | Combined preparation for the treatment of cardiovascular diseases based on chronotherapy theory |
Also Published As
Publication number | Publication date |
---|---|
AU2011339150B2 (en) | 2015-09-10 |
CO6721030A2 (es) | 2013-07-31 |
DOP2013000115A (es) | 2014-07-31 |
EA201390844A1 (ru) | 2013-11-29 |
AR084195A1 (es) | 2013-04-24 |
KR101414814B1 (ko) | 2014-07-21 |
AU2011339150A1 (en) | 2013-06-06 |
CN103249415A (zh) | 2013-08-14 |
PE20140699A1 (es) | 2014-06-13 |
CN103249415B (zh) | 2017-12-12 |
CL2013001626A1 (es) | 2013-10-04 |
KR20120089787A (ko) | 2012-08-13 |
IL226449A0 (en) | 2013-07-31 |
EP2648730A2 (fr) | 2013-10-16 |
WO2012077968A2 (fr) | 2012-06-14 |
EP2648730A4 (fr) | 2014-08-06 |
UY33772A (es) | 2012-07-31 |
MX2013005716A (es) | 2013-06-12 |
UA108277C2 (ru) | 2015-04-10 |
SG190326A1 (en) | 2013-06-28 |
BR112013013415A2 (pt) | 2019-09-24 |
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