WO2012077936A3 - Fluorescence-sensing probe, and fluorescence detection method, sentinel lymph node dissection method and target-guided surgery method which use the probe - Google Patents

Fluorescence-sensing probe, and fluorescence detection method, sentinel lymph node dissection method and target-guided surgery method which use the probe Download PDF

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Publication number
WO2012077936A3
WO2012077936A3 PCT/KR2011/009271 KR2011009271W WO2012077936A3 WO 2012077936 A3 WO2012077936 A3 WO 2012077936A3 KR 2011009271 W KR2011009271 W KR 2011009271W WO 2012077936 A3 WO2012077936 A3 WO 2012077936A3
Authority
WO
WIPO (PCT)
Prior art keywords
probe
fluorescence
target
lymph node
sentinel lymph
Prior art date
Application number
PCT/KR2011/009271
Other languages
French (fr)
Other versions
WO2012077936A2 (en
Inventor
Seok Ki Kim
Byeong Il Lee
Original Assignee
National Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Cancer Center filed Critical National Cancer Center
Publication of WO2012077936A2 publication Critical patent/WO2012077936A2/en
Publication of WO2012077936A3 publication Critical patent/WO2012077936A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/313—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)

Abstract

The present invention relates to a fluorescence-sensing probe which can detect a substance, which has been bound to or which contains therein a fluorescent dye that is distributed in a human or animal body, at high sensitivity in proximity to tissue, as well as a fluorescence detection method that uses the probe. This fluorescence-sensing probe can be used in sentinel lymph node dissection or target-guided surgery and is highly practical, because it can be suitably used for a surgical technique, such as pressing or turning the probe in proximity to the skin surface of a human or animal body during surgery.
PCT/KR2011/009271 2010-12-07 2011-12-01 Fluorescence-sensing probe, and fluorescence detection method, sentinel lymph node dissection method and target-guided surgery method which use the probe WO2012077936A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20100124466A KR101166556B1 (en) 2010-12-07 2010-12-07 Fluorescence sensing probe and fluorescence sensing method using the same
KR10-2010-0124466 2010-12-07

Publications (2)

Publication Number Publication Date
WO2012077936A2 WO2012077936A2 (en) 2012-06-14
WO2012077936A3 true WO2012077936A3 (en) 2012-10-04

Family

ID=46207576

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/009271 WO2012077936A2 (en) 2010-12-07 2011-12-01 Fluorescence-sensing probe, and fluorescence detection method, sentinel lymph node dissection method and target-guided surgery method which use the probe

Country Status (2)

Country Link
KR (1) KR101166556B1 (en)
WO (1) WO2012077936A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101674018B1 (en) * 2016-05-16 2016-11-08 (주)글로리바이오텍 Hiv diagnosis method using cd4, cd8 cell information
KR101852403B1 (en) 2017-11-17 2018-04-27 부경대학교 산학협력단 Parathyroid real-time sensing system
KR102443920B1 (en) 2020-09-28 2022-09-15 조선대학교산학협력단 Endoscope optical probe

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070003879A (en) * 2004-01-26 2007-01-05 안티캔서, 인코포레이티드 Whole body imaging using portable observation systems
KR100845425B1 (en) * 2007-01-05 2008-07-10 전남대학교산학협력단 Optical sensor probes and detection methods using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100737170B1 (en) 2006-01-20 2007-07-10 경북대학교 산학협력단 Portable quantum dot flurescent detector
JP2010104391A (en) 2008-10-28 2010-05-13 Hoya Corp Probe for fluorescent observation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070003879A (en) * 2004-01-26 2007-01-05 안티캔서, 인코포레이티드 Whole body imaging using portable observation systems
KR100845425B1 (en) * 2007-01-05 2008-07-10 전남대학교산학협력단 Optical sensor probes and detection methods using the same

Also Published As

Publication number Publication date
WO2012077936A2 (en) 2012-06-14
KR101166556B1 (en) 2012-07-19
KR20120063342A (en) 2012-06-15

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