WO2012075708A1 - Integrated infrared thermo-scan colonoscope system - Google Patents

Integrated infrared thermo-scan colonoscope system Download PDF

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Publication number
WO2012075708A1
WO2012075708A1 PCT/CN2011/070553 CN2011070553W WO2012075708A1 WO 2012075708 A1 WO2012075708 A1 WO 2012075708A1 CN 2011070553 W CN2011070553 W CN 2011070553W WO 2012075708 A1 WO2012075708 A1 WO 2012075708A1
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WO
WIPO (PCT)
Prior art keywords
infrared
thermal scanning
infrared thermal
colonoscope
scan
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PCT/CN2011/070553
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French (fr)
Chinese (zh)
Inventor
乔铁
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广州宝胆医疗器械科技有限公司
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Application filed by 广州宝胆医疗器械科技有限公司 filed Critical 广州宝胆医疗器械科技有限公司
Priority to DE212011100182U priority Critical patent/DE212011100182U1/en
Publication of WO2012075708A1 publication Critical patent/WO2012075708A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00165Optical arrangements with light-conductive means, e.g. fibre optics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/046Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for infrared imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/31Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes, colonoscopes

Definitions

  • the invention belongs to the field of medical instruments, and particularly relates to an integrated infrared thermal scanning colonoscopy system with infrared thermal scanning function. current technology
  • infrared imaging comes from military technology. It has been used for more than 40 years. With the development of various technologies such as medicine, infrared imaging and multimedia, the temperature resolution of infrared imaging has reached 0.05 degrees, and the spatial resolution has reached 0.8mrad. The image sharpness has been greatly improved, and the analysis of the results is intuitive and convenient, so its clinical application range is gradually expanding.
  • infrared imaging diagnosis shows certain advantages in the following aspects: 1) judging the location and nature of tissue pain; 2) judging the location, extent and extent of acute and chronic inflammation; 3) monitoring the blood supply function of vascular lesions; 4) Tumor warning instructions, full-course monitoring and efficacy evaluation. It can be seen that infrared imaging is an important supplement to other morphological diagnostic methods such as B-ultrasound, CT, and MR.
  • the infrared thermal scanning probe is integrated into the colonoscope, and the new technology of advanced infrared thermal scanning diagnosis is provided at the same time, providing different display modes, providing a new perspective and a new means for the diagnosis of colon diseases.
  • the object of the present invention is to overcome the deficiencies of the prior art and provide an integrated infrared thermal scanning colonoscopy system, which integrates an infrared thermal scanning probe into a colonoscopy system through an infrared thermal scanning probe.
  • Stereoscopic scanning of the colon wall and its surrounding tissues the obtained data is transmitted to the infrared thermal scanning processing system host for image processing, and provides different display mode selections, so that the doctor can analyze the colon according to different display images obtained.
  • Stereoscopic images of stereoscopic vessels have an unexpected diagnostic effect on understanding the function and pathology of the colon.
  • the integrated infrared thermal scanning colonoscopy system of the present invention comprises an infrared thermal scanning colonoscope and a cold light source host, a camera host, an endoscope monitor and an infrared thermal scanning system connected thereto, wherein the infrared thermal scanning system comprises Infrared thermal scanning processing system host and infrared thermal scanning system monitor.
  • the infrared thermal scanning colonoscope is divided into the following two according to the optical system used therein. Forms:
  • the first form is: the infrared thermal scanning colonoscope is a soft colonoscope using an electronic CCD optical system, and has a working end portion, a data connector, an operating handle and an instrument channel; the data connector and the cold light source host, The camera host is connected to the main body of the infrared thermal scanning processing system; the working end is made of soft material, has a diameter of 15 mm and a length of 2000 mm, and has a bending function at the tip end; the electronic CCD optical system is disposed at the front end of the working end portion, and has a diameter
  • the 3.0mm optical lens has a CCD chip with a size of 1/4 inch and a CCD of at least 480,000 effective pixels. The lens field of view is above 100 °; the instrument channel has a diameter of 3.0 mm.
  • the second form is: the infrared thermal scanning colonoscope is a soft colonoscope using an optical fiber optical system, and has a working end portion, a data connector, an eyepiece input end, an operating handle and an instrument channel; the data connector and The cold light source host is connected to the host of the infrared thermal scanning processing system; the eyepiece input end is connected to the camera host; the working end is made of a soft material, the diameter is 15 mm, the length is 2000 mm, and the tip end has a bending function; the optical fiber optics The system uses an optical lens with a diameter of 3.0 mm; the instrument channel has a diameter of 3.0 mm.
  • the infrared thermal scanning colonoscope integrates an infrared thermal scanning probe, an endoscope lens, and a light guiding optical fiber at a tip end portion of the working end portion thereof.
  • the infrared thermal scanning probe has a diameter of 3.0 mm, an infrared region is disposed therein, and a protective sleeve is disposed outside the infrared region, and at least one infrared device is installed in the infrared region, and the infrared device includes an infrared light source emitter and an infrared receiving lens.
  • the infrared thermal scanning colonoscope may further be provided with a micro motor, and the infrared thermal scanning probe may be extended by a micro motor to extend a plane of the colon end of the colonoscope by 10 mm to 50 mm.
  • the infrared thermal scanning probe may be rotated by the micro motor to perform a circular scan on the scanned object.
  • the infrared thermal scanning system further includes an operation panel, an operation keyboard or a handheld operation device connected to the host of the infrared thermal scanning processing system, and the operation panel and the handheld operation device are provided with control buttons. , including switch button, mode selection button, infrared intensity fine-tuning function button and monitor menu button.
  • the mode selection button is used to switch between different display modes, including the normal display mode and the night vision display mode.
  • the normal display mode refers to the display mode of infrared scanning under the illumination of the endoscope cold light source and the infrared light source
  • the night vision display mode refers to Without the endoscope cold light source and the infrared light source, depending on the different radiation intensity of the tissue, the doctor can compare the images in the two modes to obtain a better diagnostic effect from another angle.
  • the infrared panel of the infrared thermal scanning processing system is provided with an output port, and the infrared thermal scanning system monitor, an operating keyboard or a handheld operating device is connected to the output port, and the infrared thermal scanning system monitor scans and infrared heat scans. The scanning of the probes is consistent, enabling simultaneous scanning.
  • the integrated infrared thermal scanning colonoscopy system of the present invention works as follows: Colon wall and its surrounding group
  • the weaving is full of abundant blood vessels, the arterial blood temperature is high, the venous blood temperature is low, and there is some kind of heat exchange system. Both of them radiate different wavelengths of infrared rays, and the temperature of the colon wall and its surrounding tissues is not only the temperature. Under the influence of blood flow in the blood vessels, it is also affected by its own metabolism. Therefore, the temperature of the part of the colon wall and its surrounding tissues will be different due to the richness of blood vessels and the degree of metabolic activity. The wavelength of infrared rays is also different. For colonic inflammation or tumors, the temperature is significantly higher than normal due to its active metabolism.
  • blood components serum, plasma, hemoglobin, albumin, red blood cells, lymphocytes, platelets
  • infrared rays to the surrounding tissue.
  • the absorption effect is very small, the accuracy of the infrared system is less than or equal to 0.05 degrees, and the spatial resolution is at least 0.8 mrad.
  • the infrared thermal scanning probe scans at a close distance in the colon to obtain a fine and accurate infrared image.
  • the integrated infrared thermal scanning colonoscopy system of the present invention has the following working process: the infrared light of the blood flow and the tissue radiation in the blood vessel of the colon wall and its surrounding tissues, and the precise infrared detector of the infrared thermal scanning probe entering the colonic channel-
  • the processing chip converts the optical signal into an electrical signal, and after preprocessing (such as amplification, filtering, etc.), the preamplifier and the main amplifier are amplified to a certain level and then enter the infrared thermal scanning processing system host.
  • the signal input to the host also has a synchronization signal, a reference black body signal, and the like.
  • the micro-motor After the infrared thermal scanning probe is started, the micro-motor is driven to extend a certain distance from the tip end of the colonoscope, and is rotated by the micro-motor to perform circular scanning on the colon wall, and the data obtained by multi-plane continuous cross-cutting scanning is transmitted to the infrared ray.
  • the main body of the thermal scanning processing system performs image processing and outputs it to the infrared thermal scanning system monitor to clearly display the stereoscopic image of the colonic blood vessels. Through image analysis, the doctor can find that the blood vessels in the colon wall and its surrounding tissues are abnormally rich and the blood vessels are abnormally sparse. Or there are abnormal conditions such as vascular missing areas, providing doctors with immediate diagnosis basis.
  • the integrated infrared thermal scanning colonoscopy system of the present invention has the following clinical surgical methods:
  • the doctor asks the patient to make a proper position, and after disinfection and anesthesia, the infrared thermal scanning colonoscope is passed into the rectum through the anus of the patient, and the colon is scanned by infrared heat.
  • the bending function of the end of the mirror smoothly enters the colonic tract.
  • the doctor can make a clear observation through the infrared thermal scanning colonoscope, and can access the surgical instruments to treat diseases such as colon polyps.
  • the infrared thermal scanning probe located at the tip end of the infrared thermal scanning colonoscope, the infrared thermal scanning probe is extended to extend a certain distance from the apex of the colonoscope, and is rotated by the infrared scanning of the colonic tract, and output to the infrared thermal scanning system monitor to provide The basis for the doctor to diagnose the state of the colon and its surrounding tissues.
  • the infrared resolution of the current medical infrared imaging technology has high precision, and has been widely used in many fields, especially in the medical field.
  • the infrared thermal scanning probe is integrated on the colonoscope, and the infrared thermal scanning probe is rotated by the micro motor to extend the tip end of the colonoscope, and the infrared radiation formed by the temperature difference of the blood flow of the colon wall is scanned and monitored.
  • FIG. 1 is a schematic view showing the structure of an integrated infrared thermal scanning colonoscopy system according to the present invention.
  • Fig. 2A is a schematic view showing the structure of an infrared thermal scanning soft colonoscope using an electronic CCD optical system.
  • 2B is a schematic view showing the structure of an infrared thermal scanning soft colonoscope using an optical fiber optical system.
  • Fig. 3 is a schematic view showing the end structure of the infrared thermal scanning soft colonoscope shown in Figs. 2A and 2B.
  • FIG. 4 is a schematic view showing the structure of an infrared thermal scanning probe according to the present invention.
  • FIG. 5 is a schematic illustration of the surgical procedure of the integrated infrared thermal scanning colonoscopy system of the present invention. detailed description
  • the integrated infrared thermal scanning colonoscopy system of the present invention comprises an infrared thermal scanning colonoscope, a cold light source host 2, a camera host 3, an infrared thermal scanning processing system host 4, an operating keyboard or a handheld operation.
  • the infrared thermal scanning processing system host 4 is also connected with an operation panel, and the handheld operation device 5 and the operation panel are provided with control buttons such as a switch button, a mode selection button, an infrared intensity fine adjustment function button, and a monitor menu button.
  • FIG. 2A and 2B are schematic views showing the structure of two different forms of the infrared thermal scanning colonoscope 1, wherein: FIG. 2A is a schematic structural view of an infrared thermal scanning soft colonoscope using an electronic CCD optical system, the infrared thermal scanning soft texture
  • the colonoscope is provided with a soft working end 11, a data connector 12, an operating handle 13 and an instrument channel 14.
  • the data connector 12 is connected to the cold light source host 2, the camera host 3, and the infrared thermal scanning processing system host 4, respectively.
  • the soft working end portion 11 has a diameter of 15 mm and a length of 2000 mm, and its tip end portion 111 has a function of bending.
  • the electronic CCD optical system is disposed at the front end of the soft working end portion 11, and adopts an optical lens with a diameter of 3.0 mm, and the CCD chip adopts a CCD with a size of 1/4 inch and at least 480,000 effective pixels, and the lens field of view is at 100. ° Above.
  • the instrument channel 14 has a diameter of 3.0 mm.
  • FIG. 2B is a schematic view showing the structure of an infrared thermal scanning soft colonoscope using an optical fiber optical system, the infrared thermal scanning soft colonoscope having a soft working end portion 11, a data connector 12, an eyepiece input end 15, an operating handle 13 and Instrument channel 14.
  • the data connector 12 is connected to the cold light source host 2 and the infrared thermal scanning processing system host 4, respectively, and the eyepiece input terminal 15 is connected to the camera host 3.
  • the soft working end portion 11 has a diameter of 15 mm and a length of 2000 mm. Its tip end portion 111 has a function of bending.
  • the optical fiber optical system uses an optical lens having a diameter of 3.0 mm.
  • the instrument channel 14 has a diameter of 3.0 mm.
  • FIGS. 2A and 2B are schematic views showing the end structure of the infrared thermal scanning colonoscope 1 shown in FIGS. 2A and 2B.
  • the infrared thermal scanning colonoscope 1 is integrated with an endoscope lens 121 and infrared rays at the tip end portion 111 of the soft working end portion 11.
  • the probe 122 and the light guiding fiber 123 are thermally scanned, and an instrument channel outlet 141 is also provided.
  • the endoscope lens 121 has a diameter of 3.0 mm
  • the infrared thermal scanning probe 122 has a diameter of 3.0 mm.
  • the infrared thermal scanning probe 122 is provided with an infrared region 1222.
  • the infrared region 1222 is externally provided with a protective cover 1221, and the infrared region 1222 is provided with an infrared device 1223.
  • the infrared device 1223 includes an infrared light source emitter and an infrared receiving lens. Three sets of identical infrared devices 1223 are installed in the infrared region 1222, and the three sets of infrared devices 1223 are designed to be 60 degrees apart from each other.
  • the infrared thermal scanning probe 122 can be extended by the micro-motor to extend the front end of the infrared thermal scanning colonoscope by 10 mm to 50 mm, and rotate in the direction of the N-N' to perform circular scanning on the scanned body.
  • Figure 5 is a schematic illustration of the surgical procedure of the integrated infrared thermal scanning colonoscopy system of the present invention.
  • the doctor asks the patient to make a proper position.
  • the infrared thermal scanning colonoscope 1 is passed into the rectum 82 through the patient's anus 81, and the bending function of the tip end portion 111 of the colonoscope 1 is scanned by infrared heat to smoothly enter the colonic tract 8.
  • Doctors can use the infrared thermal scanning colonoscopy 1 to make a clear observation, and can be used to access surgical instruments to treat diseases such as colon polyps.
  • the infrared thermal scanning probe 122 located at the tip end portion 111 of the infrared thermal scanning colonoscope 1 is activated, and the infrared thermal scanning probe 122 is extended to extend a certain distance from the colon end portion 111, and is rotated by the infrared scanning of the colonic channel 8 to output infrared heat.
  • the scanning system monitor 6 provides a basis for the doctor to diagnose the state of the colon and its surrounding tissues.

Abstract

The invention belongs to the field of medical instrument and discloses an integrated infrared thermo-scan colonoscope system, which comprises an infrared thermo-scan colonoscope and a cold light source host, an image pickup host, an endoscope monitor and an infrared thermo-scan system connected thereto, wherein the infrared thermo-scan system comprises an infrared thermo-scan processing system host and an infrared thermo-scan system monitor. The integrated infrared thermo-scan colonoscope system integrates an infrared thermo-scan probe into a colonoscope system, performs stereoscopic annular scanning for tissues on the colon wall via the infrared thermo-scan probe, transmits the obtained data to the infrared thermo-scan processing system host to perform image processing, and provides the selection of various display modes including a normal display mode, a night vision display mode and so on, such that a doctor can know the function and lesion condition of the colon and then make an accurate diagnosis by analyzing the stereoscopic blood vessel static image of the colon on the basis of the obtained various display images.

Description

一体化红外线热扫描结肠镜系统 技术领域  Integrated infrared thermal scanning colonoscopy system
本发明属于医用器械领域,具体涉及具有红外线热扫描功能的一体化红外线热扫描结 肠镜系统。 现有技术  The invention belongs to the field of medical instruments, and particularly relates to an integrated infrared thermal scanning colonoscopy system with infrared thermal scanning function. current technology
医用红外线成像来源于军工技术, 已有 40多年的使用历史, 随着医学、 红外线成像 及多媒体等多种技术的发展, 红外线成像的温度分辨率已经达到 0.05度, 空间分辨能力 已经达到 0.8mrad, 图像清晰度有了很大的提高, 结果分析直观方便, 因而其在临床上的 应用范围正逐渐扩大。 目前, 红外线成像诊断在以下方面显示出一定优势: 1 ) 判断组织 疼痛的部位和性质; 2)判断急、 慢性炎症的部位、 范围和程度; 3 )监测血管性病变的供 血功能状态; 4)肿瘤预警指示、全程监视及疗效评估。 由此可见, 红外线成像是对 B超、 CT、 MR等其它形态学诊断方法的重要补充。  Medical infrared imaging comes from military technology. It has been used for more than 40 years. With the development of various technologies such as medicine, infrared imaging and multimedia, the temperature resolution of infrared imaging has reached 0.05 degrees, and the spatial resolution has reached 0.8mrad. The image sharpness has been greatly improved, and the analysis of the results is intuitive and convenient, so its clinical application range is gradually expanding. At present, infrared imaging diagnosis shows certain advantages in the following aspects: 1) judging the location and nature of tissue pain; 2) judging the location, extent and extent of acute and chronic inflammation; 3) monitoring the blood supply function of vascular lesions; 4) Tumor warning instructions, full-course monitoring and efficacy evaluation. It can be seen that infrared imaging is an important supplement to other morphological diagnostic methods such as B-ultrasound, CT, and MR.
将红外线热扫描探头集成于结肠镜之中,治疗的同时进行先进的红外线热扫描诊断的 新技术, 提供不同的显示模式, 为结肠病的诊断提供新的视角和新的手段。 目前尚没有出 现两者结合的一体化内窥镜系统。 发明内容  The infrared thermal scanning probe is integrated into the colonoscope, and the new technology of advanced infrared thermal scanning diagnosis is provided at the same time, providing different display modes, providing a new perspective and a new means for the diagnosis of colon diseases. There is currently no integrated endoscope system that combines the two. Summary of the invention
本发明的目的在于克服现有技术的不足, 提供一种一体化红外线热扫描结肠镜系统, 该一体化红外线热扫描结肠镜系统将红外线热扫描探头集成在结肠镜系统中,通过红外线 热扫描探头对结肠壁及其周边组织进行立体的扫描,得到的数据传输至红外线热扫描处理 系统主机进行图像处理,并提供不同的显示模式选择,使得医生能根据获得的不同的显示 图像, 通过分析结肠的立体血管静态图像, 对于了解结肠的功能和病变情况, 具有意想不 到的诊断效果。  The object of the present invention is to overcome the deficiencies of the prior art and provide an integrated infrared thermal scanning colonoscopy system, which integrates an infrared thermal scanning probe into a colonoscopy system through an infrared thermal scanning probe. Stereoscopic scanning of the colon wall and its surrounding tissues, the obtained data is transmitted to the infrared thermal scanning processing system host for image processing, and provides different display mode selections, so that the doctor can analyze the colon according to different display images obtained. Stereoscopic images of stereoscopic vessels have an unexpected diagnostic effect on understanding the function and pathology of the colon.
本发明的目的是通过以下技术方案来实现的:  The object of the present invention is achieved by the following technical solutions:
本发明所述的一体化红外线热扫描结肠镜系统,包括红外线热扫描结肠镜以及与之连 接的冷光源主机、摄像主机、 内镜监视器和红外线热扫描系统, 所述的红外线热扫描系统 包括红外线热扫描处理系统主机和红外线热扫描系统监视器。  The integrated infrared thermal scanning colonoscopy system of the present invention comprises an infrared thermal scanning colonoscope and a cold light source host, a camera host, an endoscope monitor and an infrared thermal scanning system connected thereto, wherein the infrared thermal scanning system comprises Infrared thermal scanning processing system host and infrared thermal scanning system monitor.
在本发明中,所述的红外线热扫描结肠镜按其所采用的光学系统的不同,分为以下两 种形式: In the present invention, the infrared thermal scanning colonoscope is divided into the following two according to the optical system used therein. Forms:
第一种形式是: 所述红外线热扫描结肠镜为采用电子 CCD光学系统的软质结肠镜, 其上设有工作端部、数据接头、操作手柄和器械通道; 该数据接头与冷光源主机、摄像主 机和红外线热扫描处理系统主机相连接; 该工作端部采用软质材料制造, 直径 15mm, 长度 2000mm, 先端部具有弯曲的功能; 该电子 CCD光学系统设置在工作端部的前端, 采用直径 3.0mm的光学镜头,其 CCD芯片采用尺寸 1/4〃 、至少 48万有效像素的 CCD, 镜头视场角在 100 ° 以上; 该器械通道的直径 3.0mm。  The first form is: the infrared thermal scanning colonoscope is a soft colonoscope using an electronic CCD optical system, and has a working end portion, a data connector, an operating handle and an instrument channel; the data connector and the cold light source host, The camera host is connected to the main body of the infrared thermal scanning processing system; the working end is made of soft material, has a diameter of 15 mm and a length of 2000 mm, and has a bending function at the tip end; the electronic CCD optical system is disposed at the front end of the working end portion, and has a diameter The 3.0mm optical lens has a CCD chip with a size of 1/4 inch and a CCD of at least 480,000 effective pixels. The lens field of view is above 100 °; the instrument channel has a diameter of 3.0 mm.
第二种形式是:所述红外线热扫描结肠镜为采用光导纤维光学系统的软质结肠镜,其 上设有工作端部、数据接头、 目镜输入端、操作手柄和器械通道; 该数据接头与冷光源主 机和红外线热扫描处理系统主机相连接;该目镜输入端与摄像主机相连接;该工作端部采 用软质材料制造, 直径 15mm, 长度 2000mm, 先端部具有弯曲的功能; 该光导纤维 光学系统采用直径 3.0mm的光学镜头; 该器械通道的直径 3.0mm。  The second form is: the infrared thermal scanning colonoscope is a soft colonoscope using an optical fiber optical system, and has a working end portion, a data connector, an eyepiece input end, an operating handle and an instrument channel; the data connector and The cold light source host is connected to the host of the infrared thermal scanning processing system; the eyepiece input end is connected to the camera host; the working end is made of a soft material, the diameter is 15 mm, the length is 2000 mm, and the tip end has a bending function; the optical fiber optics The system uses an optical lens with a diameter of 3.0 mm; the instrument channel has a diameter of 3.0 mm.
在本发明中,所述的红外线热扫描结肠镜在其工作端部的先端部集成有红外线热扫描 探头、 内镜镜头和导光光纤。 所述红外线热扫描探头的直径 3.0mm, 其内设有红外区, 红外区的外部设有保护套,红外区内至少安装有一组红外装置,所述红外装置包括红外光 源发射器和红外接收镜头。所述红外线热扫描结肠镜内还可以设有微型电机,所述红外线 热扫描探头在微型电机的驱动下, 可以伸出结肠镜先端部平面 10mm〜50mm。 优选地, 红外区内安装有三组相同的红外装置, 该三组红外装置互成 60度设计。 所述红外线热扫 描探头可以在微型电机的驱动下旋转, 从而对被扫描体做环形扫描。  In the present invention, the infrared thermal scanning colonoscope integrates an infrared thermal scanning probe, an endoscope lens, and a light guiding optical fiber at a tip end portion of the working end portion thereof. The infrared thermal scanning probe has a diameter of 3.0 mm, an infrared region is disposed therein, and a protective sleeve is disposed outside the infrared region, and at least one infrared device is installed in the infrared region, and the infrared device includes an infrared light source emitter and an infrared receiving lens. . The infrared thermal scanning colonoscope may further be provided with a micro motor, and the infrared thermal scanning probe may be extended by a micro motor to extend a plane of the colon end of the colonoscope by 10 mm to 50 mm. Preferably, three sets of identical infrared devices are installed in the infrared region, and the three groups of infrared devices are designed to each other at a 60 degree. The infrared heat scanning probe can be rotated by the micro motor to perform a circular scan on the scanned object.
在本发明中,所述红外线热扫描系统还包括有与所述红外线热扫描处理系统主机相连 接的操作面板、操作键盘或手持操作设备,所述的操作面板和手持操作设备上设有控制按 钮, 包括开关按钮、模式选择按钮、 红外强度微调功能按钮和监视器菜单按钮。模式选择 按钮用于切换不同的显示模式,包括普通显示模式和夜视显示模式,普通显示模式是指红 外扫描在内镜冷光源和红外光源的照射下进行的显示模式,夜视显示模式是指没有内镜冷 光源和红外光源的照射下,依靠组织物的自身不同辐射强度来成像, 医生对两种模式下的 图像对比分析,可以得到另外一个角度的更好的诊断效果。所述红外线热扫描处理系统主 机的后面板设有输出端口,所述的红外线热扫描系统监视器、操作键盘或手持操作设备连 接于该输出端口,红外线热扫描系统监视器的扫描与红外线热扫描探头的扫描相一致,实 现同步扫描。  In the present invention, the infrared thermal scanning system further includes an operation panel, an operation keyboard or a handheld operation device connected to the host of the infrared thermal scanning processing system, and the operation panel and the handheld operation device are provided with control buttons. , including switch button, mode selection button, infrared intensity fine-tuning function button and monitor menu button. The mode selection button is used to switch between different display modes, including the normal display mode and the night vision display mode. The normal display mode refers to the display mode of infrared scanning under the illumination of the endoscope cold light source and the infrared light source, and the night vision display mode refers to Without the endoscope cold light source and the infrared light source, depending on the different radiation intensity of the tissue, the doctor can compare the images in the two modes to obtain a better diagnostic effect from another angle. The infrared panel of the infrared thermal scanning processing system is provided with an output port, and the infrared thermal scanning system monitor, an operating keyboard or a handheld operating device is connected to the output port, and the infrared thermal scanning system monitor scans and infrared heat scans. The scanning of the probes is consistent, enabling simultaneous scanning.
本发明所述的一体化红外线热扫描结肠镜系统,其工作原理如下: 结肠壁及其周边组 织布满了丰富的血管, 动脉血温度较高, 静脉血温度较低, 两者存在某种热交换机制, 两 者都向外辐射不同波长的红外线,结肠壁及其周边组织自身的温度不但受到血管内血流的 影响,也受自身新陈代谢的影响,所以结肠壁及其周边组织内发生异变的部分的温度会由 于血管丰富与否和新陈代谢活跃程度的不同而表现出差异性,对外辐射的红外线的波长也 各不相同, 对于结肠炎症或者肿瘤等病变, 由于其新陈代谢活跃, 其温度明显高于正常。 研究表明, 血液中的成分(血清、血浆、血红蛋白、 白蛋白、 红细胞、淋巴细胞、血小板) 在光谱中对红外光的吸收最低,意味着血液除了对外辐射红外线外,还对周围组织的红外 线的吸收影响很小,红外线系统的精度小于等于 0.05度,空间分辨能力至少达到 0.8mrad, 红外线热扫描探头在结肠道内近距离进行扫描, 得到精细精确的红外图像。 The integrated infrared thermal scanning colonoscopy system of the present invention works as follows: Colon wall and its surrounding group The weaving is full of abundant blood vessels, the arterial blood temperature is high, the venous blood temperature is low, and there is some kind of heat exchange system. Both of them radiate different wavelengths of infrared rays, and the temperature of the colon wall and its surrounding tissues is not only the temperature. Under the influence of blood flow in the blood vessels, it is also affected by its own metabolism. Therefore, the temperature of the part of the colon wall and its surrounding tissues will be different due to the richness of blood vessels and the degree of metabolic activity. The wavelength of infrared rays is also different. For colonic inflammation or tumors, the temperature is significantly higher than normal due to its active metabolism. Studies have shown that blood components (serum, plasma, hemoglobin, albumin, red blood cells, lymphocytes, platelets) have the lowest absorption of infrared light in the spectrum, meaning that in addition to external radiation, the blood also has infrared rays to the surrounding tissue. The absorption effect is very small, the accuracy of the infrared system is less than or equal to 0.05 degrees, and the spatial resolution is at least 0.8 mrad. The infrared thermal scanning probe scans at a close distance in the colon to obtain a fine and accurate infrared image.
本发明所述的一体化红外线热扫描结肠镜系统,其工作过程如下: 结肠壁及其周边组 织血管中血流及组织辐射的红外线,经进入结肠道内的红外线热扫描探头的精密红外探测 器-红外接收镜头接收后, 处理芯片将光信号转换成电信号, 经过预处理(如放大、 滤波 等), 由前置放大器和主放大器放大到一定电平之后便进入红外线热扫描处理系统主机。 同时输入主机的信号还有同步信号、参照黑体信号等。红外线热扫描探头启动后, 在微型 电机的驱动下伸出结肠镜先端部若干距离,并在微型电机的驱动下旋转,对结肠壁做环形 扫描, 多平面连续横切扫描得到的数据传输至红外线热扫描处理系统主机进行图像处理, 并输出到红外线热扫描系统监视器,清晰地显示结肠的立体血管静态图像, 医生通过图像 分析,可以发现结肠壁及其周边组织内血管异常丰富、血管异常稀疏或者存在血管缺失区 域等异常情况, 给医生及时提供即时的诊断依据。  The integrated infrared thermal scanning colonoscopy system of the present invention has the following working process: the infrared light of the blood flow and the tissue radiation in the blood vessel of the colon wall and its surrounding tissues, and the precise infrared detector of the infrared thermal scanning probe entering the colonic channel- After receiving the infrared receiving lens, the processing chip converts the optical signal into an electrical signal, and after preprocessing (such as amplification, filtering, etc.), the preamplifier and the main amplifier are amplified to a certain level and then enter the infrared thermal scanning processing system host. At the same time, the signal input to the host also has a synchronization signal, a reference black body signal, and the like. After the infrared thermal scanning probe is started, the micro-motor is driven to extend a certain distance from the tip end of the colonoscope, and is rotated by the micro-motor to perform circular scanning on the colon wall, and the data obtained by multi-plane continuous cross-cutting scanning is transmitted to the infrared ray. The main body of the thermal scanning processing system performs image processing and outputs it to the infrared thermal scanning system monitor to clearly display the stereoscopic image of the colonic blood vessels. Through image analysis, the doctor can find that the blood vessels in the colon wall and its surrounding tissues are abnormally rich and the blood vessels are abnormally sparse. Or there are abnormal conditions such as vascular missing areas, providing doctors with immediate diagnosis basis.
本发明所述的一体化红外线热扫描结肠镜系统,其临床手术方法如下: 医生要求患者 作适当体位, 消毒麻醉后, 把红外线热扫描结肠镜经患者肛门处通入直肠, 通过红外线热 扫描结肠镜端部的弯曲功能,顺利进入结肠道内, 医生可以通过红外线热扫描结肠镜做清 晰的观察, 并可以通入手术器械, 治疗结肠息肉等病症。启动位于红外线热扫描结肠镜先 端部的红外线热扫描探头,红外线热扫描探头启动后伸出结肠镜先端部若干距离,为结肠 道做旋转的红外线热扫描,输出到红外线热扫描系统监视器,提供医生诊断结肠道及其周 边组织状态的依据。  The integrated infrared thermal scanning colonoscopy system of the present invention has the following clinical surgical methods: The doctor asks the patient to make a proper position, and after disinfection and anesthesia, the infrared thermal scanning colonoscope is passed into the rectum through the anus of the patient, and the colon is scanned by infrared heat. The bending function of the end of the mirror smoothly enters the colonic tract. The doctor can make a clear observation through the infrared thermal scanning colonoscope, and can access the surgical instruments to treat diseases such as colon polyps. Initiating an infrared thermal scanning probe located at the tip end of the infrared thermal scanning colonoscope, the infrared thermal scanning probe is extended to extend a certain distance from the apex of the colonoscope, and is rotated by the infrared scanning of the colonic tract, and output to the infrared thermal scanning system monitor to provide The basis for the doctor to diagnose the state of the colon and its surrounding tissues.
与现有技术相比,本发明的有益效果是: 目前的医用红外成像技术的红外分辨率的精 度很高, 而且已经逐渐广泛应用在很多领域, 特别是医疗领域。将红外线热扫描探头集成 在结肠镜上, 利用红外线热扫描探头在微型电机驱动下旋转, 伸出结肠镜先端部, 对结肠 壁血管血液运动产生的温度差异而形成的红外线辐射进行扫描监测,多平面连续横切扫描 得到的数据传输至红外线热扫描处理系统主机进行图像处理,清晰地显示结肠的立体血管 静态图像,为医生判断结肠的病变及功能状态提供可靠的客观依据,丰富结肠疾病的诊断 手段, 有效地提高诊断的准确性。 附图说明 Compared with the prior art, the beneficial effects of the present invention are: The infrared resolution of the current medical infrared imaging technology has high precision, and has been widely used in many fields, especially in the medical field. The infrared thermal scanning probe is integrated on the colonoscope, and the infrared thermal scanning probe is rotated by the micro motor to extend the tip end of the colonoscope, and the infrared radiation formed by the temperature difference of the blood flow of the colon wall is scanned and monitored. Plane continuous cross-cut scan The obtained data is transmitted to the host of the infrared thermal scanning processing system for image processing, and the static image of the stereoscopic blood vessels of the colon is clearly displayed, which provides a reliable objective basis for the doctor to judge the pathological and functional state of the colon, enriches the diagnosis means of colon diseases, and effectively improves The accuracy of the diagnosis. DRAWINGS
图 1是本发明所述的一体化红外线热扫描结肠镜系统的结构示意图。  1 is a schematic view showing the structure of an integrated infrared thermal scanning colonoscopy system according to the present invention.
图 2A是采用电子 CCD光学系统的红外线热扫描软质结肠镜的结构示意图。  Fig. 2A is a schematic view showing the structure of an infrared thermal scanning soft colonoscope using an electronic CCD optical system.
图 2B是采用光导纤维光学系统的红外线热扫描软质结肠镜的结构示意图。  2B is a schematic view showing the structure of an infrared thermal scanning soft colonoscope using an optical fiber optical system.
图 3是图 2A和图 2B所示红外线热扫描软质结肠镜的端部结构示意图。  Fig. 3 is a schematic view showing the end structure of the infrared thermal scanning soft colonoscope shown in Figs. 2A and 2B.
图 4是本发明所述的红外线热扫描探头的结构示意图。  4 is a schematic view showing the structure of an infrared thermal scanning probe according to the present invention.
图 5是本发明所述的一体化红外线热扫描结肠镜系统的手术方法示意图。 具体实施方式  Figure 5 is a schematic illustration of the surgical procedure of the integrated infrared thermal scanning colonoscopy system of the present invention. detailed description
下面结合附图对本发明作进一步的详述:  The present invention will be further described in detail below with reference to the accompanying drawings:
如图 1所示,本发明所述的一体化红外线热扫描结肠镜系统包括有红外线热扫描结肠 镜 1、冷光源主机 2、摄像主机 3、 红外线热扫描处理系统主机 4、操作键盘或手持操作设 备 5、 红外线热扫描系统监视器 6和内镜监视器 7。 其中, 红外线热扫描处理系统主机 4 还连接有操作面板, 手持操作设备 5和操作面板上设有开关按钮、模式选择按钮、红外强 度微调功能按钮和监视器菜单按钮等控制按钮。  As shown in FIG. 1 , the integrated infrared thermal scanning colonoscopy system of the present invention comprises an infrared thermal scanning colonoscope, a cold light source host 2, a camera host 3, an infrared thermal scanning processing system host 4, an operating keyboard or a handheld operation. The device 5, the infrared thermal scanning system monitor 6, and the endoscope monitor 7. The infrared thermal scanning processing system host 4 is also connected with an operation panel, and the handheld operation device 5 and the operation panel are provided with control buttons such as a switch button, a mode selection button, an infrared intensity fine adjustment function button, and a monitor menu button.
图 2A和图 2B显示了红外线热扫描结肠镜 1的两种不同形式的结构示意图, 其中: 图 2A为采用电子 CCD光学系统的红外线热扫描软质结肠镜的结构示意图, 该红外 线热扫描软质结肠镜设有软质工作端部 11、 数据接头 12、 操作手柄 13和器械通道 14。 数据接头 12分别与冷光源主机 2、 摄像主机 3和红外线热扫描处理系统主机 4相连接。 软质工作端部 11的直径 15mm, 长度 2000mm, 其先端部 111具有弯曲的功能。 所述 的电子 CCD光学系统设置在软质工作端部 11 的前端, 采用直径 3.0mm的光学镜头, 其 CCD芯片采用尺寸 1/4〃 、 至少 48万有效像素的 CCD, 镜头视场角在 100 ° 以上。 器械通道 14的直径 3.0mm。  2A and 2B are schematic views showing the structure of two different forms of the infrared thermal scanning colonoscope 1, wherein: FIG. 2A is a schematic structural view of an infrared thermal scanning soft colonoscope using an electronic CCD optical system, the infrared thermal scanning soft texture The colonoscope is provided with a soft working end 11, a data connector 12, an operating handle 13 and an instrument channel 14. The data connector 12 is connected to the cold light source host 2, the camera host 3, and the infrared thermal scanning processing system host 4, respectively. The soft working end portion 11 has a diameter of 15 mm and a length of 2000 mm, and its tip end portion 111 has a function of bending. The electronic CCD optical system is disposed at the front end of the soft working end portion 11, and adopts an optical lens with a diameter of 3.0 mm, and the CCD chip adopts a CCD with a size of 1/4 inch and at least 480,000 effective pixels, and the lens field of view is at 100. ° Above. The instrument channel 14 has a diameter of 3.0 mm.
图 2B为采用光导纤维光学系统的红外线热扫描软质结肠镜的结构示意图, 该红外线 热扫描软质结肠镜设有软质工作端部 11、 数据接头 12、 目镜输入端 15、 操作手柄 13和 器械通道 14。 数据接头 12分别与冷光源主机 2和红外线热扫描处理系统主机 4相连接, 而目镜输入端 15与摄像主机 3相连接。软质工作端部 11的直径 15mm,长度 2000mm, 其先端部 111具有弯曲的功能。 所述的光导纤维光学系统采用直径 3.0mm的光学镜头。 器械通道 14的直径 3.0mm。 2B is a schematic view showing the structure of an infrared thermal scanning soft colonoscope using an optical fiber optical system, the infrared thermal scanning soft colonoscope having a soft working end portion 11, a data connector 12, an eyepiece input end 15, an operating handle 13 and Instrument channel 14. The data connector 12 is connected to the cold light source host 2 and the infrared thermal scanning processing system host 4, respectively, and the eyepiece input terminal 15 is connected to the camera host 3. The soft working end portion 11 has a diameter of 15 mm and a length of 2000 mm. Its tip end portion 111 has a function of bending. The optical fiber optical system uses an optical lens having a diameter of 3.0 mm. The instrument channel 14 has a diameter of 3.0 mm.
图 3为图 2A和图 2B所示的红外线热扫描结肠镜 1的端部结构示意图, 该红外线热 扫描结肠镜 1在其软质工作端部 11的先端部 111集成有内镜镜头 121、 红外线热扫描探 头 122和导光光纤 123, 并且还设有器械通道出口 141。 内镜镜头 121的直径 3.0mm, 而红外线热扫描探头 122的直径 3.0mm。  3 is a schematic view showing the end structure of the infrared thermal scanning colonoscope 1 shown in FIGS. 2A and 2B. The infrared thermal scanning colonoscope 1 is integrated with an endoscope lens 121 and infrared rays at the tip end portion 111 of the soft working end portion 11. The probe 122 and the light guiding fiber 123 are thermally scanned, and an instrument channel outlet 141 is also provided. The endoscope lens 121 has a diameter of 3.0 mm, and the infrared thermal scanning probe 122 has a diameter of 3.0 mm.
图 4是本发明所述的红外线热扫描探头 122的结构示意图,该红外线热扫描探头 122 内设有红外区 1222, 红外区 1222的外部设有保护套 1221, 红外区 1222内安装有红外装 置 1223, 该红外装置 1223包括有红外光源发射器和红外接收镜头。 红外区 1222内安装 有三组相同的红外装置 1223,三组红外装置 1223互成 60度设计。红外线热扫描探头 122 可以在微型电机的驱动下, 伸出所述红外线热扫描结肠镜先端部 10mm〜50mm, 并且绕 着 N-N'的方向旋转, 从而对被扫描体做环形的扫描。  4 is a schematic structural view of the infrared thermal scanning probe 122 according to the present invention. The infrared thermal scanning probe 122 is provided with an infrared region 1222. The infrared region 1222 is externally provided with a protective cover 1221, and the infrared region 1222 is provided with an infrared device 1223. The infrared device 1223 includes an infrared light source emitter and an infrared receiving lens. Three sets of identical infrared devices 1223 are installed in the infrared region 1222, and the three sets of infrared devices 1223 are designed to be 60 degrees apart from each other. The infrared thermal scanning probe 122 can be extended by the micro-motor to extend the front end of the infrared thermal scanning colonoscope by 10 mm to 50 mm, and rotate in the direction of the N-N' to perform circular scanning on the scanned body.
图 5是本发明所述的一体化红外线热扫描结肠镜系统的手术方法示意图。医生要求患 者作适当体位, 消毒麻醉后, 把红外线热扫描结肠镜 1经患者肛门 81处通入直肠 82, 通 过红外线热扫描结肠镜 1的先端部 111的弯曲功能,顺利进入结肠道 8内, 医生可以通过 红外线热扫描结肠镜 1做清晰的观察, 并可以通入手术器械, 治疗结肠息肉等病症。启动 位于红外线热扫描结肠镜 1先端部 111的红外线热扫描探头 122, 红外线热扫描探头 122 启动后伸出结肠镜先端部 111若干距离, 为结肠道 8做旋转的红外线热扫描,输出到红外 线热扫描系统监视器 6, 提供医生诊断结肠道及其周边组织状态的依据。  Figure 5 is a schematic illustration of the surgical procedure of the integrated infrared thermal scanning colonoscopy system of the present invention. The doctor asks the patient to make a proper position. After disinfection and anesthesia, the infrared thermal scanning colonoscope 1 is passed into the rectum 82 through the patient's anus 81, and the bending function of the tip end portion 111 of the colonoscope 1 is scanned by infrared heat to smoothly enter the colonic tract 8. Doctors can use the infrared thermal scanning colonoscopy 1 to make a clear observation, and can be used to access surgical instruments to treat diseases such as colon polyps. The infrared thermal scanning probe 122 located at the tip end portion 111 of the infrared thermal scanning colonoscope 1 is activated, and the infrared thermal scanning probe 122 is extended to extend a certain distance from the colon end portion 111, and is rotated by the infrared scanning of the colonic channel 8 to output infrared heat. The scanning system monitor 6 provides a basis for the doctor to diagnose the state of the colon and its surrounding tissues.

Claims

权 利 要 求 书 Claim
1、 一体化红外线热扫描结肠镜系统, 其特征在于: 包括红外线热扫描结肠镜以及与 之连接的冷光源主机、摄像主机、 内镜监视器和红外线热扫描系统, 所述的红外线热扫描 系统包括红外线热扫描处理系统主机和红外线热扫描系统监视器。 1. An integrated infrared thermal scanning colonoscopy system, comprising: an infrared thermal scanning colonoscope and a cold light source host connected thereto, a camera host, an endoscope monitor and an infrared thermal scanning system, wherein the infrared thermal scanning system Including infrared thermal scanning processing system host and infrared thermal scanning system monitor.
2、 根据权利要求 1所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描结肠镜设有工作端部、 数据接头和器械通道。  2. The integrated infrared thermal scanning colonoscopy system according to claim 1, wherein: the infrared hot scanning colonoscope is provided with a working end portion, a data connector and an instrument channel.
3、 根据权利要求 2所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描结肠镜在其工作端部的先端部集成有红外线热扫描探头、 内镜镜头和导光光 纤。  3. The integrated infrared thermal scanning colonoscopy system according to claim 2, wherein: the infrared thermal scanning colonoscope is integrated with an infrared thermal scanning probe, an endoscope lens and a guide at a front end portion of the working end portion thereof. Optical fiber.
4、 根据权利要求 3所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描探头内设有红外区,所述红外区的外部设有保护套,所述的红外区内至少安装 有一组红外装置, 所述的红外装置包括红外光源发射器和红外接收镜头。  The integrated infrared thermal scanning colonoscopy system according to claim 3, wherein: the infrared thermal scanning probe is provided with an infrared region, and the infrared region is provided with a protective sleeve, the infrared At least one infrared device is installed in the zone, and the infrared device includes an infrared light source emitter and an infrared receiving lens.
5、 根据权利要求 4所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外区内安装有三组红外装置, 该三组红外装置互成 60度设计。  The integrated infrared thermal scanning colonoscopy system according to claim 4, wherein: three infrared devices are installed in the infrared region, and the three infrared devices are designed to be 60 degrees apart from each other.
6、 根据权利要求 3所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描结肠镜内设有用于驱动所述红外线热扫描探头伸缩和旋转的电机。  6. The integrated infrared thermal scanning colonoscopy system according to claim 3, wherein: the infrared hot scanning colonoscope is provided with a motor for driving the infrared thermal scanning probe to expand and contract.
7、 根据权利要求 1所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描结肠镜为采用电子 CCD光学系统的软质结肠镜。  7. The integrated infrared thermal scanning colonoscopy system according to claim 1, wherein: the infrared thermal scanning colonoscope is a soft colonoscope using an electronic CCD optical system.
8、 根据权利要求 1所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描结肠镜为采用光导纤维光学系统的软质结肠镜, 其上还设有目镜输入端。  8. The integrated infrared thermal scanning colonoscopy system according to claim 1, wherein: the infrared thermal scanning colonoscope is a soft colonoscope using an optical fiber optical system, and an eyepiece input end is further disposed thereon. .
9、 根据权利要求 1所述的一体化红外线热扫描结肠镜系统, 其特征在于: 所述的红 外线热扫描系统还包括与所述红外线热扫描处理系统主机相连接的操作面板、操作键盘或 手持操作设备,所述的操作面板和手持操作设备上设有控制按钮,所述的控制按钮包括开 关按钮、设有普通显示模式和夜视显示模式的模式选择按钮、红外强度微调功能按钮和监 视器菜单按钮。  9. The integrated infrared thermal scanning colonoscopy system according to claim 1, wherein: said infrared thermal scanning system further comprises an operation panel, an operation keyboard or a hand-held unit connected to said infrared thermal scanning processing system main body. The operating device, the operation panel and the handheld operating device are provided with control buttons, the control button comprises a switch button, a mode selection button with a normal display mode and a night vision display mode, an infrared intensity fine adjustment function button and a monitor Menu button.
PCT/CN2011/070553 2010-12-10 2011-01-25 Integrated infrared thermo-scan colonoscope system WO2012075708A1 (en)

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