WO2012058031A3 - Nouveau procédé de préparation de bisnorcymérine et ses sels - Google Patents

Nouveau procédé de préparation de bisnorcymérine et ses sels Download PDF

Info

Publication number
WO2012058031A3
WO2012058031A3 PCT/US2011/056415 US2011056415W WO2012058031A3 WO 2012058031 A3 WO2012058031 A3 WO 2012058031A3 US 2011056415 W US2011056415 W US 2011056415W WO 2012058031 A3 WO2012058031 A3 WO 2012058031A3
Authority
WO
WIPO (PCT)
Prior art keywords
bisnorcymerine
salts
preparation
novel method
bisnorcymserine
Prior art date
Application number
PCT/US2011/056415
Other languages
English (en)
Other versions
WO2012058031A2 (fr
Inventor
Maria Maccecchini
Original Assignee
Qr Pharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qr Pharma, Inc. filed Critical Qr Pharma, Inc.
Publication of WO2012058031A2 publication Critical patent/WO2012058031A2/fr
Publication of WO2012058031A3 publication Critical patent/WO2012058031A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La présente invention concerne un nouveau procédé de préparation de N1,N8-bisnorcymsérine. Elle concerne également un procédé de préparation de 1:1 sel de (--)-N1,N8-bisnorcymsérine avec un acide.
PCT/US2011/056415 2010-10-28 2011-10-14 Nouveau procédé de préparation de bisnorcymérine et ses sels WO2012058031A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40774310P 2010-10-28 2010-10-28
US61/407,743 2010-10-28

Publications (2)

Publication Number Publication Date
WO2012058031A2 WO2012058031A2 (fr) 2012-05-03
WO2012058031A3 true WO2012058031A3 (fr) 2014-04-10

Family

ID=45994656

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/056415 WO2012058031A2 (fr) 2010-10-28 2011-10-14 Nouveau procédé de préparation de bisnorcymérine et ses sels

Country Status (1)

Country Link
WO (1) WO2012058031A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1349858B1 (fr) * 2000-11-02 2008-08-27 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Agents permettant la reduction de la proteine precurseur amyloide et le traitement de la demence et procede d'utilisation de tels agents
US7662816B2 (en) * 2003-08-08 2010-02-16 Schering Corporation Cyclic amine BACE-1 inhibitors having a benzamide substituent

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1349858B1 (fr) * 2000-11-02 2008-08-27 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Agents permettant la reduction de la proteine precurseur amyloide et le traitement de la demence et procede d'utilisation de tels agents
US7662816B2 (en) * 2003-08-08 2010-02-16 Schering Corporation Cyclic amine BACE-1 inhibitors having a benzamide substituent

Also Published As

Publication number Publication date
WO2012058031A2 (fr) 2012-05-03

Similar Documents

Publication Publication Date Title
WO2012087288A3 (fr) Compositions de sels métalliques
PL2630108T3 (pl) Sposób wytwarzania 2,3,3,3-tetrafluoropropenu
WO2012025944A3 (fr) Sitagliptine, sels et polymorphes de celle-ci
IL243188A (en) Method for Producing Crystalline Derivatives 7, 6 Saturation - 7 - Morphine Carbamoyl and its salts
WO2013003669A3 (fr) Compositions, méthodes d'utilisation et méthodes de traitement
PL2531505T3 (pl) Sposób wytwarzania kompleksów 3,7-diaza-bicyklo[3.3.1]nonanu z metalami
EP2562152A4 (fr) Procédé de préparation d'acide 2,5-diméthylphénylacétique
BR112014026149A2 (pt) método para a preparação de 2,4-ácido dihidroxibutírico (2,4-dhb) e microrganismo.
WO2011088027A8 (fr) Composés et procédés
HRP20181437T1 (hr) Postupak proizvodnje (3s,3s') 4,4' disulfanedilbis (3-aminobutan-1-sulfonske kiseline)
WO2013055687A3 (fr) R(+)-n-formyl-propargyl-aminoindane
PT2591091E (pt) Método para a preparação de 1,3-propanodiol a partir de sacarose
WO2009117381A3 (fr) Préparation de montélukast et ses sels
WO2012017448A3 (fr) Sels de la lapatinib
EP2840088A4 (fr) Procédé de préparation d'acide 5,6,4'-trihydroxyflavone-7-0-d-glucuronique
EP2759547A4 (fr) Groupe partant contenant des dérivés amino ou alkylamino d'acide succinique du composé de platine, son procédé de préparation et ses applications
WO2012063115A3 (fr) Procédé de préparation de rosuvastatine calcique via un nouvel intermédiaire amine
EP2634183B8 (fr) Procédé de préparation de 1,3,5-trioxane
WO2009122429A3 (fr) Oxybutynine cristalline et son procédé de préparation
WO2014184756A3 (fr) Procédé pour la formation d'arformotérol ou d'un sel de celui-ci
SI2626428T1 (sl) Postopek za encimsko sintezo (7S)-3,4-dimetoksibiciklo(4.2.0)okta-1,3, 5-trien-7-karboksilne kisline ali njenih estrov ter uporaba sinteze ivabradina in njegovih soli
EP2457921A4 (fr) Dérivés d'acides auréoliques, leur procédé d'obtention et leurs utilisations
HK1212321A1 (en) Crystalline phase of (3s.3s) 4,4-disulfanediylbis(3-aminobutane 1 - sulfonic acid) with l-lysine (3s3s)-44-(3--1-) l-
WO2012058031A3 (fr) Nouveau procédé de préparation de bisnorcymérine et ses sels
PL393268A1 (pl) Kwas 2-amino-6-dihydroksyborylo-1,2,3,4-tetrahydronaftaleno-2-karboksylowy i sposób jego wytwarzania

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11836860

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 11836860

Country of ref document: EP

Kind code of ref document: A2