WO2012055587A1

WO2012055587A1 - Active ingredient combination and anti-dandruff hair treatment products iii

Info

Publication number: WO2012055587A1
Application number: PCT/EP2011/059039
Authority: WO
Inventors: Volker Scheunemann; Erik Schulze Zur Wiesche
Original assignee: Henkel Ag & Co. Kgaa
Priority date: 2010-10-28
Filing date: 2011-06-01
Publication date: 2012-05-03
Also published as: DE102010043074A1; EP2632422A1

Abstract

Rapidly effective high-performance anti-dandruff products which are gentle on the scalp and hair and which do not negatively influence the hair with respect to its combability, shine and suppleness contain, based on their weight, 0.0001 to 5% by weight of epsilon poly-L-lysine of the general formula (I), wherein n represents integer numbers between 5 and 100 and 0.01 to 10% by weight of climbazole.

Description

"Active substance combination and hair treatment agent for dandruff IM"

The invention relates to a cosmetic hair treatment agent based on a specific combination of active ingredients, a method using the means and the use of the means for the prophylaxis, reduction, elimination and alleviation of dandruff on hairy body surfaces.

Skin and hair cleansers, such as those commercially available as liquid soaps, shampoos, shower baths, bubble baths, shower gels, and wash gels, not only must have good detergency, but should also be well tolerated by the skin and hair if used frequently, do not cause excessive defatting or dryness.

An important aspect of hair cleansing and care is the fight against dandruff, because even the slight appearance of dandruff on the scalp or other hairy body regions is considered a sign of lack of care. In addition, dandruff is usually accompanied by itching, which is perceived as disturbing. Itching, on the other hand, causes scratching reactions, which can lead to injuries of the affected skin, which in turn can form the basis for infections and pathogenic agents. The requirements for a cosmetic remedy for dandruff are therefore high, because on the one hand the scalp should be thoroughly and permanently freed of dandruff, and on the other hand, the remedy for hair and scalp should be well tolerated.

Another important requirement is to have the fastest possible effect, so that the above-mentioned chain of disadvantages does not occur at all.

From the literature, a variety of hair cosmetics are known to prevent or reduce dandruff. The choice is usually made in the form of shampoos, lotions or hair lotions.

EP-A-348 015 discloses the use of zinc salts as anti-dandruff agents.

The combination of three conventional and effective antidandruff agents is the subject of EP 1 238 645 B1. Therein are 1 - (4-chlorophenoxy) -1- (1H-imidazolyl) -3,3-dimethyl-2-butanone (INCI name: climbazole), bis (1-hydroxy-2- (1H) -pyridineethionato ) Zinc (INCI name: Zinc Pyrithione) and 1-hydroxy-4-methyl-6- (2,4,4-trimethylpentyl) -2- (1H) pyridinone, 2-aminoethanol salt (INCI name: Piroctone Olamine ) are already combined at low levels of use to produce an antidandruff agent that prevents or reduces the formation of dandruff. A disadvantage of the means of the prior art has been that they were effective against dandruff, but this effect only after frequent use occurred.

Therefore, it was an additional object of the present invention to find a fast dandruff agent that is gentle on the scalp and the hair and does not adversely affect the hair in terms of its combability, its shine and suppleness. In addition, the anti-dandruff effect of known drugs should, if possible, not only be accelerated, but also increased as far as possible.

This object has been achieved by using the antidandruff active ingredient climbazole in combination with a special epsilon-poly-L-amino acid in a composition suitable for use on hairy body surfaces.

Surprisingly, it was found that hair treatment with cosmetic products based on this combination resulted in a significantly faster and more intensive action than conventional compositions.

The invention therefore hair treatment compositions containing - based on their weight - a) 0.0001 to 5 wt .-% E silane poly-L-lysine of the general formula (I)

where n stands for integers between 5 and 100,

b) from 0.01 to 10% by weight of climbazole.

As the first essential ingredient, the compositions according to the invention contain epsilon-poly-L-lysine, an oligomer or polymer of the natural amino acid lysine, which is also referred to as epsilon-polylysine due to its linkage in epsilon position. This compound leads to an increase in the activity and acceleration of the antidandruff active ingredient, which goes beyond the own antidandruff effect of epsilon-poly-L-lysine.

In preferred compositions of the invention epsilon-poly-L-lysine is used within narrower ranges. Hair treatment agents preferred according to the invention are characterized in that they contain from 0.0005 to 4, preferably from 0.001 to 3, more preferably from 0.005 to 2 and in particular from 0.01 to 1% by weight of epsilon-poly-L-lysine of the general formula (I) ,

The degree of polymerization of the epsilon-poly-L-lysines used according to the invention is between 5 and 100. Depending on the hair treatment agent and use concentration, it was possible to observe an optimum effect for polymers within narrower degrees of polymerization. Accordingly, hair treatment agents according to the present invention containing epsilon-poly-L-lysine of the general formula (I) in which n is an integer of 10 to 70, preferably from 15 to 60, more preferably from 20 to 50 and in particular for the numbers 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35.

Very particularly preferred hair treatment compositions according to the invention contain 0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 23 and / or n = 24 and / or n = 25 and / or n = 26 and / or n = 27 and / or n = 28 and / or n = 29 and / or n = 30 and / or n = 31 and / or n = 32 and / or n = 33 and / or n = 34, wherein the total amount of epsilon-poly-L-Lysinen of the general formula (I) according to the invention is 0.0001 to 5 wt .-%.

As a second essential ingredient, the agents according to the invention contain from 0.01 to 10% by weight of climbazole. Climbazole is a chemical compound that is antifungal and fungistatic. It comes in the form of a racemate in the trade

The exact name of the compound is (RS) -1- (4-chlorophenoxy) - 1- (1 / - / - imidazol-1-yl) - 3,3-dimethylbutan-2-one, the INCI name is Climbazole.

Climbazole is also used in preferred compositions according to the invention within narrower ranges. Hair treatment agents preferred according to the invention are characterized in that they contain 0.02 to 7.5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole.

Very particularly preferred hair treatment compositions according to the invention contain

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 23 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 24 and 0.02 bis 7.5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 25 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 26 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 27 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 28 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 29 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 30 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 31 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 32 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or

0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 33 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole and / or 0.0005 to 4, preferably 0.001 to 3, more preferably 0.005 to 2 and in particular 0.01 to 1 wt .-% epsilon-poly-L-lysine of the general formula (I) with n = 34 and 0.02 to 7 , 5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5 wt .-% climbazole,

wherein the total amount of epsilon-poly-L-lysines of the general formula (I) according to the invention is 0.0001 to 5 wt .-%.

Most preferably, the amounts of epsilon-poly-L-lysine (s) and climbazole are coordinated to achieve the greatest possible increase in effectiveness and effectiveness. Hair treatment compositions according to the invention are preferred here which comprise a total amount of epsilon-poly-L-lysine of the general formula (I) (ingredient a)) and climbazole (ingredient b)) of 0.01 to 2% by weight, preferably of 0, 1 to 1, 75 wt .-%, more preferably from 0.25 to 1, 5 wt .-% and in particular from 0.5 to 1, 25 wt .-%.

Since scalp dandruff is often associated with a very dry skin, it is preferred to incorporate moisturizing agents in the compositions of the invention. As a particularly compatible with the combination of the invention, certain active ingredients have been found so that preferred hair treatment compositions of the invention contain at least one moisturizing active ingredient from the group pantolactone, glycerol, allantoin, panthenol, isopentyl.

Irrespective of the nature of the preferred moisturizing active ingredient and whether only such an active ingredient is used or mixtures of these active ingredients are used, hair treatment compositions according to the invention are preferred, the or the moisturizing active substance (s) in amounts of 0, 1 to 10 Wt .-%, preferably from 0, 15 to 7.5 wt .-%, more preferably from 0.2 to 5 wt .-% and in particular from 0.25 to 4 wt .-%.

Very particularly preferred hair treatment compositions according to the invention with various moisturizing active substances and the respective quantities are disclosed on pages 6 to 17 of the priority document.

The cosmetic compositions preferably further contain at least one member selected from the group consisting of anionic, amphoteric, zwitterionic, nonionic, cationic surfactants or mixtures thereof, water-insoluble oil components, vitamins, provitamins, protein hydrolysates, plant extracts, UV filter, Amino acids, water-insoluble silicones, water-soluble silicones and / or amodimethicones

Hair treatment compositions which are preferred according to the invention are characterized in that they contain, based on their weight, from 0.5 to 70% by weight, preferably from 1 to 60% by weight and in particular from 5 to 25% by weight of anionic and / or nonionic (s) and / or cationic and / or amphoteric surfactant (s).

Suitable anionic surfactants and emulsifiers for the compositions according to the invention are all anionic surfactants suitable for use on the human body. These are characterized by a water-solubilizing, anionic Group such as As a carboxylate, sulfate, sulfonate or phosphate group and a lipophilic alkyl group having about 8 to 30 carbon atoms. In addition, glycol or polyglycol ether groups, ester, ether and amide groups as well as hydroxyl groups may be present in the molecule. Examples of suitable anionic surfactants and emulsifiers are, in each case in the form of the sodium, potassium and ammonium as well as the mono-, di- and trialkanolammonium salts having 2 to 4 C atoms in the alkanol group,

linear and branched fatty acids with 8 to 30 carbon atoms (soaps),

Ethercarbonsäuren the formula R-0- (CH ₂ -CH ₂ 0) _x -CH ₂ -COOH, in which R is a linear alkyl group having 8 to 30 carbon atoms and x = 0 or 1 to 16,

Acylsarcosides having 8 to 24 carbon atoms in the acyl group,

Acyltaurides having 8 to 24 carbon atoms in the acyl group,

Acyl isethionates having 8 to 24 carbon atoms in the acyl group,

linear alkanesulfonates having 8 to 24 C atoms,

linear alpha-olefin sulfonates having 8 to 24 C atoms,

Alpha-sulfofatty acid methyl esters of fatty acids having 8 to 30 carbon atoms,

Acylglutamates of the formula (T1),

XOOC-CH ₂ CH ₂ CH-COOX (T1)

I

HN-COR

in which R CO is a linear or branched acyl radical having 6 to 22 carbon atoms and 0, 1, 2 or 3 double bonds and X is hydrogen, an alkali and / or alkaline earth metal, ammonium, alkylammonium, alkanolammonium or glucammonium, for example acylglutamates, which from fatty acids having 6 to 22, preferably 12 to 18 carbon atoms, such as C ₁₂ / 14- or Ci ₂ / i8-coconut fatty acid, lauric acid, myristic acid, palmitic acid and / or stearic acid, particularly sodium N-cocoyl and sodium N-stearoyl-L-glutamate,

Esters of a hydroxy-substituted di- or tricarboxylic acid of the general formula (T2),

X

I

HOCCOOR (T2)

I

Y is CHCOOR ² wherein X is H or a -CH ₂ COOR group, Y is H or -OH is under the condition that Y is H when X is -CH ₂ COOR, R, R and R ² independently of one another denote a hydrogen atom, an alkali metal or alkaline earth metal cation, an ammonium group which is a cation of an ammonium organic base or a Z radical derived from a polyhydroxylated organic compound selected from the group of etherified (C ₆ -C ₁₈ ) Alkyl polysaccharides with 1 to 6 monomeric saccharide units and / or the etherified aliphatic (C ₆ -C ₆ ) -hydroxyalkylpolyols having 2 to 16 hydroxyl radicals, with the proviso that at least one of the groups R, R or R ^{2 is} a radical Z,

Esters of sulfosuccinic acid or sulfosuccinates of the general formula (T3I),

H ₂ COOR (T3)

I

_M (n ₊ / n) -Q _3S _ Q _H _COOR ² in the M ^{(n + / n)} for n = 1, a hydrogen atom, an alkali metal cation, an ammonium group or the cation of an ammonium organic base and for n = 2 Represents alkaline earth metal cation and R and R ^{2 are} independently a hydrogen atom, an alkali or alkaline earth metal cation, an ammonium group, the cation of an ammonium organic base or a radical Z derived from a polyhydroxylated organic compound selected from the group of etherified (C ₆ -C ₈₎ -Alkylpolysaccharide having 1 to 6 monomeric saccharide units and / or etherified aliphatic (C ₆ -C ₆₎ -hydroxyalkylpolyols is selected having 2 to 16 hydroxyl radicals, among the proviso that at least one of the groups R or R ² Rest Z is,

Sulfosuccinic acid mono- and dialkyl esters having 8 to 24 C atoms in the alkyl group and sulfosuccinic monoalkylpolyoxyethyl esters having 8 to 24 C atoms in the alkyl group and 1 to 6 oxyethyl groups,

Alkyl sulfates and alkyl polyglycol ether sulfates of the formula R- (O-CH ₂ -CH ₂ ) x -OSO ₃ H, in which R is a preferably linear alkyl group having 8 to 30 C atoms and x = 0 or 1 - 12,

mixed surface-active hydroxysulfonates according to DE-A-37 25 030,

Esters of tartaric acid and citric acid with alcohols, the addition products of about 2-15 molecules of ethylene oxide and / or propylene oxide to C ₈ . _{2 represent} 2-fatty alcohols,

Alkyl and / or alkenyl ether phosphates,

sulfated fatty acid alkylene glycol esters,

Monoglyceride sulfates and monoglyceride ether sulfates.

Preferred anionic surfactants and emulsifiers are acylglutamates, acyl isethionates, acyl sarcosinates and acyl taurates, each with a linear or branched acyl radical having 6 to 22 carbon atoms and 0, 1, 2 or 3 double bonds, which in particularly preferred embodiments of an octanoyl, decanoyl, lauroyl , Myristoyl, palmitoyl and stearoyl radical, esters of tartaric acid, citric acid or succinic acid or of the salts of these acids with alkylated glucose, in particular the products with the INCI name Disodium Coco-Glucoside Citrate, Sodium Coco-Glucoside Tartrate and Disodium Coco-glucosides sulfosuccinates, alkyl polyglycol ether sulfates and ether carboxylic acids having 8 to 18 C atoms in the alkyl group and up to 12 ethoxy groups in the molecule, sulfosuccinic acid mono- and dialkyl esters having 8 to 18 C atoms in the alkyl group and sulfosuccinic monoalkylpolyoxyethyl esters having 8 to 18 C atoms in the alkyl group and 1 to 6 ethoxy groups.

Zwitterionic surfactants and emulsifiers are surface-active compounds which contain at least one quaternary ammonium group and at least one in the molecule - carry or -S0 ₃ ^<_) group - COO ^<_). Particularly suitable zwitterionic surfactants and emulsifiers are the so-called betaines, such as N-alkyl-N, N-dimethylammonium glycinates, for example cocoalkyldimethylammonium glycinate, N-acylaminopropyl-N, N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3 carboxymethyl-3-hydroxyethyl-imidazolines each having 8 to 18 carbon atoms in the alkyl or acyl group, and the cocoacylaminoethylhydroxyethylcarboxymethylglycinate. A preferred zwitterionic surfactant is the fatty acid amide derivative known by the INCI name Cocamidopropyl Betaine.

Further preferred anionic surfactants are alkyl sulfates, alkyl polyglycol ether sulfates and ether carboxylic acid salts having 10 to 18 C atoms in the alkyl group and up to 12 glycol ether groups in the molecule and sulfosuccinic acid mono- and dialkyl esters having 8 to 18 C atoms in the alkyl group and sulfosuccinic monoalkylpolyoxyethylester with 8 to 18 carbon atoms in the alkyl group and 1 to 6 oxyethyl groups.

Particularly preferred anionic surfactants are the alkali metal or ammonium salts of lauryl ether sulfate having a degree of ethoxylation of 2 to 4 EO.

Particularly preferred hair treatment compositions according to the invention are characterized in that they contain - based on their weight - 0.1 to 20 wt .-%, preferably 0.25 to 17.5 wt .-% and in particular 5 to 15 wt .-% of anionic (s ) Surfactant (s), more preferably fatty alcohol ether sulfates of the formula

H ₃ C- (CH 2) n - (OCH 2 CH 2) _k -OSO 3 ^" M ⁺

in which n represents values of from 5 to 21, preferably from 7 to 19, particularly preferably from 9 to 17 and in particular from 1 to 13 and k for values of 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10, preferably 1, 2 or 3 and especially 2, and M is a cation from the group Na ⁺ , K ⁺ NH ₄ ⁺ , Mg ²⁺ , Zn ²⁺ , preferably Na ⁺ ,

Zwitterionic surfactants and emulsifiers are surface-active compounds which contain at least one quaternary ammonium group and at least one in the molecule - carry or -S0 ₃ ^<_) group - COO ^<_). Particularly suitable zwitterionic surfactants and emulsifiers are the so-called betaines, such as N-alkyl-N, N-dimethylammonium glycinates, for example cocoalkyldimethylammonium glycinate, N-acylaminopropyl-N, N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3 carboxymethyl-3-hydroxyethyl-imidazolines each having 8 to 18 carbon atoms in the alkyl or acyl group, and the cocoacylaminoethylhydroxyethylcarboxymethylglycinate. A preferred zwitterionic surfactant is the fatty acid amide derivative known by the INCI name Cocamidopropyl Betaine. Ampholytic surfactants and emulsifiers are understood to mean those surface-active compounds which, apart from a C ₈ -C ₂₄ -alkyl or -acyl group, contain at least one free amino group and at least one -COOH or -SO ₃ H group and are capable of forming internal salts , Examples of suitable ampholytic surfactants are N-alkylglycines, N-alkylaminopropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids each having about 8 to 24 C atoms in the alkyl group. Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and the d ₂ -C ₈ -acylsarcosine.

Particularly preferred hair treatment compositions according to the invention are characterized in that they contain amphoteric surfactant (s) from the groups of N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids containing around 8 to 24 carbon atoms in the alkyl group, alkyl aminoacetic acids containing around 8 to 24 carbon atoms in the alkyl group, N-cocoalkylaminopropionate, cocoacylaminoethyl aminopropionate C ₁₂ - C ₈ - acyl sarcosine, N-alkyl - Ν, Ν-dimethylammonium glycinates, for example, cocoalkyl dimethylammoniumglycinat, N-acylaminopropyl-N, N-dimethylammoniumglycinate, for example Kokosacylaminopropyl- dimethylammoniumglycinat, 2-alkyl-3-carboxymethyl-3-hydroxyethyl-imidazolines each having 8 to 18 C. -Atomen in the alkyl or acyl group, Kokosacylaminoethylhydroxyethylcarboxymethyl- glycinate, under the INCI name cocamidopropyl betaine bek compounds which contain compounds known by the INCI name Disodium Cocoamphodiacetate, preferred agents comprising the amphoteric surfactant (s) in amounts of from 0.5 to 9% by weight, preferably from 0.75 to 8 Wt .-% and in particular from 1 to 7.5 wt .-%, each based on the total agent included.

Particularly preferred hair treatment agents contain as amphoteric surfactants betaines of the formula (T4)

in which R is a straight-chain or branched, saturated or mono- or polyunsaturated alkyl or alkenyl radical having 8 to 24 carbon atoms.

These surfactants are referred to the INCI nomenclature as Amidopropylbetaine, wherein the representatives derived from coconut fatty acids are preferred and are referred to as Cocoamidopropylbetaine. According to the invention, particular preference is given to using surfactants of the formula (T4) which are a mixture of the following representatives:

H ₃ C- (CH ₂₎ ₇ -C (0) -NH- (CH ₂₎ ₃ N ⁺ (CH ₃₎ ₂ CH ₂ COO ^~, H ₃ C- (CH ₂₎ ₉ -C (0) -NH - (CH ₂₎ ₃ N ⁺ (CH ₃₎ ₂ CH ₂ COO ^~, H ₃ C- (CH ₂₎ ₁₁ -C (0) -NH- (CH ₂₎ ₃ N ⁺ (CH ₃₎ ₂ CH ₂ COO ^" , H ₃ C- (CH ₂ ) ₁₃ -C (O) -NH- (CH ₂ ) ₃ N ⁺ (CH ₃ ) ₂ CH ₂ COO ^" , H ₃ C- (CH ₂₎ ₁₅ -C (0) -NH- (CH ₂₎ ₃ N ⁺ (CH ₃₎ ₂ CH ₂ COO ^~, H ₃ C- (CH ₂₎ ₇ -CH = CH- (CH ₂ ) ₇ -C (O) -NH- (CH ₂ ) ₃ N ⁺ (CH ₃ ) ₂ CH ₂ COO ^~

Particular preference is given to using surfactants of the formula (T4) within narrower ranges of amounts. Here, agents according to the invention are preferred which, based on their weight, are from 0.25 to 8% by weight, more preferably from 0.5 to 7% by weight, more preferably from 0.75 to 6.5% by weight and in particular 1 to 5.5 wt .-% of surfactant (s) of the formula (T4).

In addition to the amphoteric surfactant (s) of the formula (T4) or in its place, the hair-treatment compositions according to the invention can be used with particular preference as amphoteric surfactants betaines of the formula (T5)

These surfactants are referred to according to the INCI nomenclature as amphoacetates, wherein the representatives derived from coconut fatty acids are preferred and are referred to as cocoamphoactetates.

For manufacturing reasons surfactants of this type often also contain betaines of the formula (T5a)

in which R is a straight-chain or branched, saturated or mono- or polyunsaturated alkyl or alkenyl radical having 8 to 24 carbon atoms and M is a cation. These surfactants are referred to according to the INCI nomenclature as Amphodiacetate, wherein the representatives derived from coconut fatty acids are preferred and are referred to as Cocoamphodiactetate.

According to the invention, particular preference is given to using surfactants of the formula (T5) which are a mixture of the following representatives:

H ₃ C- (CH ₂ ) ₇ -C (O) -NH- (CH ₂ ) ₂ NH ⁺ (CH ₂ CH ₂ OH) CH ₂ CH ₂ COO ^" , H ₃ C- (CH ₂ ) ₉ -C ( 0) -NH- (CH ₂ ) ₂ NH ⁺ (CH ₂ CH ₂ OH) CH ₂ CH ₂ COO ^~ , HaC-iCHzJu-CiOJ-NH-iCHz NH ^ CHzCHzOHJCHzCHzCOO ^" , H ₃ C- (CH ₂ ) ₁₃ - C (O) -NH- (CH ₂ ) ₂ NH ⁺ (CH ₂ CH ₂ OH) CH ₂ CH ₂ COO ^" , H ₃ C- (CH ₂ ) ₁₅ -C (O) -NH- (CH ₂₎ ₂ NH ⁺ (CH ₂ CH ₂ OH) CH ₂ CH ₂ COO ^~, H ₃ C- (CH ₂₎ ₇ -CH = CH- (CH ₂₎ ₇ -C (0) -NH- (CH ₂₎ ₂ NH ⁺ (CH ₂ CH ₂ OH) CH ₂ CH ₂ COO ^~

Particular preference is given to using surfactants of the formula (T5) within narrower ranges of amounts. Here, agents according to the invention are preferred which, based on their weight, are from 0.25 to 8% by weight, more preferably from 0.5 to 7% by weight, more preferably from 0.75 to 6.5% by weight and in particular 1 to 5.5 wt .-% of surfactant (s) of the formula (T5).

In summary, hair treatment agents according to the invention are preferred in which the radical R in the formulas (VI) and (VII) is selected from H ₃ C- (CH ₂ ) ₇ -, H ₃ C- (CH ₂ ) _9- , H ₃ C- (CH ₂ ) n, H ₃ C- (CH ₂ ) i3-, H ₃ C- (CH ₂ ) i5-, H ₃ C- (CH ₂ ) ₇ -CH = CH- (CH ₂ ) ₇ - or Mixtures of these.

Particularly preferred nonionic surfactants are alkyl polyglycosides. Accordingly, hair treatment compositions according to the invention are preferred which contain as nonionic surfactants - based on their weight - 0, 1 to 20 wt .-% alkylpolyglycosides of the general formula RO- (Z) _x , where R is alkyl, Z for sugar and x for the number the sugar units stands.

Alkylpolyglycosides (APG) are nonionic surfactants made entirely from renewable resources (sugar building blocks, predominantly glucose, for example from corn starch and fatty alcohol, for example from coconut oil). Alkyl polyglycosides are accessible by acid-catalyzed reaction (Fischer reaction) of sugars, especially glucose (or starch) or butyl glycosides with fatty alcohols.

Complex mixtures of alkyl monoglucoside (alkyl-α-D- and β-D-glucopyranoside and small amounts of glucofuranoside), alkyldiglucosides (-isomaltosides, maltosides, etc.) and alkyl oligoglucosides (maltotriosides, tetraosides, etc.) are formed. The average degree of polymerization of commercial products whose alkyl radicals are in the range C8-C16 is 1, 2-1, 5.

According to the invention, preference is given to using alkylpolyglycosides corresponding to the general formula RO - (Z) _x , where R is alkyl, Z is sugar and x is the number of sugar units. Particular preference is given to those alkylpolyglycosides in which R

consisting essentially of C ₈ and C 10 -alkyl groups,

essentially of C ₂ - and Ci4 alkyl groups,

consisting essentially of C ₈ - to C 16 -alkyl groups or

consisting essentially of Ci ₂ - to Ci6-alkyl groups or

essentially from d ₆ to C- | ₈ alkyl groups

consists.

As sugar building block Z it is possible to use any desired mono- or oligosaccharides. Usually, sugars with 5 or 6 carbon atoms and the corresponding oligosaccharides are used. Such sugars are, for example, glucose, fructose, galactose, arabinose, ribose, xylose, lyxose, allose, altrose, mannose, gulose, idose, talose and sucrose. Preferred sugar building blocks are glucose, fructose, galactose, arabinose and sucrose; Glucose is particularly preferred. The alkylpolyglycosides which can be used according to the invention contain on average 1, 1 to 5 sugar units. Alkyl polyglycosides having x values of 1.1 to 2.0 are preferred. Very particular preference is given to alkyl glycosides in which x is 1: 1 to 1, 8.

Other surfactants which can be used particularly advantageously in the compositions according to the invention, especially in admixture with alkylpolyglycosides, are glutamates, asparaginates and sulfoacetates. Here, hair treatment compositions according to the invention are preferred which contain, based on their weight, from 0.1 to 20% by weight of fatty acid glutamates (acylglutamates) and / or fatty acid asparaginates (acylasparaginates) and / or alkylsulfoacetates (sulfoacetic acid alkyl esters).

Acylglutamate can be defined by the formula

in which R-CO is a linear or branched acyl radical having 6 to 22 carbon atoms and 0 and / or 1, 2 or 3 double bonds and X is hydrogen, an alkali and / or alkaline earth metal, ammonium, alkylammonium, alka nolammonium or glucammonium stands.

Surprisingly, it has been found that blends of alkyl glucosides with acyl glutamates have a very good dermatological compatibility and an improved foamability both with regard to the base foam and the foam stability in the presence of water hardness.

Acylglutamates are known anionic surfactants which can be obtained, for example, by Schotten-Baumann acylation of glutamic acid with fatty acids, fatty acid esters or chlorides. Products for sale are available, for example, from Hoechst AG, Frankfurt / DE or Ajinomoto Co. Inc., Tokyo / JP.

Typical examples of suitable acylglutamates are anionic surfactants derived from fatty acids having 6 to 22, preferably 12 to 18 carbon atoms, such as C 12/14 and C 12/18 coconut fatty acid, lauric acid, myristic acid, palmitic acid and / or stearic acid. Particularly preferred are sodium N-cocoyl and sodium N-stearoyl-L-glutamate The compositions according to the invention may contain the alkyl and / or alkenyl oligoglucosides and the acyl glutamates in a weight ratio of 1:99 to 99: 1, preferably 10:90 to 90:10 and in particular 80:20 to 50:50.

Acylasparaginates can be defined by the formula

in which R-CO is a linear or branched acyl radical having 6 to 22 carbon atoms and 0 and / or 1, 2 or 3 double bonds and X is hydrogen, an alkali and / or alkaline earth metal, ammonium, alkylammonium, alkanolammonium or glucammonium ,

Acylasparaginates are known anionic surfactants which can be obtained, for example, by Schotten-Baumann acylation of aspartic acid with fatty acids, fatty acid esters or chlorides. Products for sale are available, for example, from Hoechst AG, Frankfurt / DE or Ajinomoto Co. Inc., Tokyo / JP.

Typical examples of suitable acylasparaginates are anionic surfactants derived from fatty acids having 6 to 22, preferably 12 to 18 carbon atoms, such as C12 / 14 or C12 / 18 coconut fatty acid, lauric acid, myristic acid, palmitic acid and / or stearic acid. Particularly preferred are sodium N-cocoyl and sodium N-stearoyl-L-aspartate

The agents according to the invention may also contain the alkyl and / or alkenyl oligoglucosides and the acylasparaginates in a weight ratio of 1:99 to 99: 1, preferably 10:90 to 90:10 and in particular 80:20 to 50:50.

Sulfoacetates (sulfoacetic acid esters), are usually salts of esters of sulfoacetic acid and can be represented by the general formula

R-0-C (O) -CH ₂ -SO ₂ -OX

in which R is a linear or branched alkyl or alkenyl radical having 6 to 22 carbon atoms and 0 and / or 1, 2 or 3 double bonds and X is hydrogen, an alkali and / or alkaline earth metal, ammonium, alkylammonium, alkanolammonium or glucammonium stands. Particularly preferred is the use of the sodium salt of sulfoacetic acid with the INCI name: sodium lauryl sulfoacetate):

H ₃ C- (CH ₂ ) ₁₁ -O-CO-CH ₂ -SO ₂ -ONa

Sodium lauryl sulphoacetate is a white, free-flowing powder which reacts neutrally, with good foaming power, wetting power and dispersibility.

Cationic surfactants of the quaternary ammonium compound type, the esterquats and the amidoamines can be used according to the invention. Preferred quaternary ammonium compounds are ammonium halides, in particular chlorides and bromides, such as alkyltrimethylammonium chlorides, dialkyldimethylammonium chlorides and trialkylmethylammonium chlorides. The long alkyl chains of these surfactants preferably have 10 to 18 carbon atoms, such as. In cetyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, distearyl dimethyl ammonium chloride, lauryl dimethyl ammonium chloride, lauryl dimethyl benzyl ammonium chloride and tricetylmethyl ammonium chloride. Further preferred cationic surfactants are the imidazolium compounds known under the INCI names Quaternium-27 and Quaternium-83.

Particularly preferred hair treatment compositions according to the invention are characterized in that they contain as cationic care substance - based on their weight - 0.05 to 7.5 wt .-%, preferably 0.1 to 5 wt .-%, particularly preferably 0.2 to 3, 5 wt .-% and in particular 0.25 to 2.5 wt .-% cationic (s) surfactant (s) from the group of quaternary ammonium compounds and / or the esterquats and / or the amidoamines containing preferred cationic (s) Surfactant (s) is / are selected

- Alkyltrimethylammoniumchloriden having preferably 10 to 18 carbon atoms in the alkyl radical and / or

Dialkyldimethylammoniumchloride having preferably 10 to 18 carbon atoms in the alkyl radical and / or

- Trialkylmethylammoniumchloride preferably having 10 to 18 carbon atoms in the alkyl radical and / or

Cetyltrimethylammonium chloride and / or

Stearyltrimethylammonium chloride and / or

Distearyldimethylammonium chloride and / or

Lauryldimethylammonium chloride and / or

Lauryldimethylbenzylammoniumchlorid and / or

- tricetylmethylammonium chloride

Quaternium-27 and / or

Quaternium-83 and / or N-methyl-N (2-hydroxyethyl) -N, N- (ditalgacyloxyethyl) ammonium methosulfate and / or

N-methyl-N (2-hydroxyethyl) -N, N- (distearoyloxyethyl) ammonium methosulfate and / or

N, N-dimethyl-N, N-distearoyloxyethyl ammonium chloride and / or N, N-di- (2-hydroxyethyl) -N, N- (fatty acid ethyl) ammonium chloride. The care effects of the compositions according to the invention can be further enhanced by using certain care substances. Preferably, these are selected from certain groups of known care substances, since these care substances harmonize perfectly with the formulation and the care effect with the combination used according to the invention against dandruff.

Hair treatment compositions which are preferred according to the invention are characterized in that they additionally have care substance (s), based on their weight, in amounts of from 0.001 to 10% by weight, preferably from 0.005 to 7.5% by weight, particularly preferably from 0.01 to 5 Wt .-% and in particular 0.05 to 2.5 wt .-%, with preferred care substance (s) are selected from the group i. L-carnitine and / or its salts;

ii. Taurine and / or its salts;

iii. niacinamide;

iv. ubiquinone

v. Ectoin;

Preferred hair treatment compositions according to the invention are characterized in that they contain from -0.001 to 10% by weight, preferably 0.005 to 7.5% by weight, particularly preferably 0.01 to 5% by weight and in particular 0.05% by weight contain up to 2.5 wt .-% L-carnitine or L-carnitine derivatives, preferred L-carnitine derivatives are selected from acetyl-L-carnitine, L-carnitine fumarate, L-carnitine citrate, lauroyl-L-carnitine and in particular L-carnitine tartrate.

Another, more preferably usable care substance which has activating properties is taurine. According to the invention preferred hair treatment compositions contain - based on their weight - 0.01 to 15 wt .-%, preferably 0.025 to 12.5 wt .-%, particularly preferably 0.05 to 10 wt .-%, more preferably 0, 1 to 7 , 5 wt .-% and in particular 0.5 to 5 wt .-% taurine (2-aminoethanesulfonic acid).

Another preferred group of care agents in the compositions according to the invention are vitamins, provitamins or vitamin precursors. These are described below:

The group of substances referred to as vitamin A include retinol (vitamin A-1) and 3,4-didehydroretinol (vitamin A ₂ ). The ß-carotene is the provitamin of retinol. As vitamin A component according to the invention, for example, vitamin A acid and its esters, vitamin A aldehyde and vitamin A alcohol and its esters such as the palmitate and the acetate into consideration. The agents according to the invention preferably contain the vitamin A component in amounts of 0.05-1% by weight, based on the total preparation. The vitamin B group or the vitamin B complex include, among others

Vitamin B-ι (thiamine)

Vitamin B ₂ (riboflavin)

Vitamin B ₃ . Preferred according to the invention is the nicotinic acid amide which is contained in the agents used according to the invention preferably in amounts of from 0.05 to 1% by weight, based on the total agent.

Vitamin B ₅ (pantothenic acid, panthenol and pantolactone). Panthenol and / or pantolactone are preferably used in the context of this group (see below). The said compounds of the vitamin B ₅ type are preferably contained in the agents according to the invention in amounts of 0.05-10% by weight, based on the total agent. Amounts of 0.1-5 wt .-% are particularly preferred.

Vitamin B ₆ (pyridoxine and pyridoxamine and pyridoxal).

Vitamin C (ascorbic acid). Vitamin C is used in the inventive compositions preferably in amounts of 0, 1 to 3 wt .-%, based on the total agent. Use in the form of palmitic acid ester, glucosides or phosphates may be preferred. The use in combination with tocopherols may also be preferred.

Vitamin E (tocopherols, especially α-tocopherol). Tocopherol and its derivatives, which include in particular the esters such as the acetate, the nicotinate, the phosphate and the succinate, are preferably present in the agents according to the invention in amounts of 0.05-1% by weight, based on the total agent.

Vitamin F. The term "vitamin F" is usually understood as meaning essential fatty acids, in particular linoleic acid, linolenic acid and arachidonic acid.

Vitamin H. Vitamin H is the compound (3aS, 4S, 6aR) -2-oxohexahydrothienol [3,4-cf] - imidazole-4-valeric acid, for which, however, the trivial name biotin has meanwhile prevailed. Biotin is preferably present in the compositions according to the invention in amounts of from 0.0001 to 1.0% by weight, in particular in amounts of from 0.001 to 0.01% by weight.

In summary, hair-treatment compositions according to the invention are preferred which, based on their weight, are 0.1 to 5% by weight, preferably 0.2 to 4% by weight, more preferably 0.25 to 3.5% by weight, more preferably Contain 0.5 to 3 wt .-% and in particular 0.5 to 2.5 wt .-% vitamins and / or pro-vitamins and / or vitamin precursors, preferably the groups A, B, C, E, F and H. 2,4,4-dihydroxy-A / - (3-hydroxypropyl) -3,3-dimethylbutyramide, provitamin B ₅ ) and / or pantothenic acid (vitamin B ₃ , vitamin B ₅ ) and / or Niacin, niacinamide or nicotinamide (vitamin B ₃ ) and / or L-ascorbic acid (vitamin C) and / or thiamine (vitamin B) and / or riboflavin (vitamin B ₂ , vitamin G) and / or biotin (vitamin B ₇ , vitamin H) and / or folic acid (vitamin B ₉ , vitamin B _c or vitamin M) and / or vitamin B ₆ and / or vitamin B ₁₂ . It has been shown that certain quinones have a special suitability as a care substance. As a further care substance, the compositions according to the invention can therefore contain from 0.0001 to 5% by weight of at least one biochinone of the formula (Ubi)

contained in the

X, Y, Z are independently -O- or -NH- or NR ⁴ - or a chemical bond

R, R ² , R ³ independently of one another represent a hydrogen atom or an optionally substituted aryl group or an optionally substituted (C 1 -C 6) -alkyl group or a hydroxyalkyl group or a polyhydroxyalkyl group or an optionally substituted (d-Ce) -alkylene group, or a ( C 1 -C 6) -acyl radical, preferred radicals being selected independently of one another from -H, CH 3, -CH 2 CH 3, - (CH 2) 2 CH 2, -CH (CH 3) 2, - (CH 2) 3 CH 3, -CH (CH 3) CH 2 CH 3, CH ₂ CH (CH ₃ ) ₂ , -C (CH ₃ ) ₃

R ⁴ is -CH ₃ , -CH ₂ CH ₃ , - (CH ₂ ) ₂ CH ₂ , -CH (CH ₃ ) ₂ ,

(CH ₂ ) ₃ CH ₃ , -CH (CH ₃ ) CH ₂ CH ₃ , -CH ₂ CH (CH ₃ ) ₂ , -C (CH ₃ ) ₃

n stands for values from 1 to 20, preferably from 2 to 15 and in particular for 5, 6, 7, 8, 9, 10.

Particularly preferred hair treatment compositions according to the invention are characterized in that they contain as care substance - based on their weight - 0.0001 to 1 wt .-%, preferably 0.001 to 0.5 wt .-% and particularly preferably 0.005 to 0, 1 wt .-% containing at least one ubiquinone and / or at least one ubiquinol and / or at least one derivative of these substances, preferred agents containing a ubiquinone of the formula (Ubi)

(Ubi)

in which n stands for the values = 6, 7, 8, 9 or 10, particularly preferably 10 (coenzyme Q10). As an alternative to the particularly preferred ubiquinones or in addition to them, the agents according to the invention may also contain plastoquinones. Here, preferred agents according to the invention are characterized in that they are 0.0002 to 4 wt .-%, preferably 0.0005 to 3 wt .-%, particularly preferably 0.001 to 2 wt .-%, more preferably 0.0015 to 1 and in particular 0.002 to 0.5 wt .-% of at least one plastoquinone of the formula (Ubi-b)

in which n stands for values of 1 to 20, preferably of 2 to 15 and in particular for 5, 6, 7, 8, 9, 10, whereby particularly preferred means Plastochinon PQ-9 of the formula

contain.

As a further care enhancer, the agents according to the invention may contain ectoin. Hair treatment compositions which are preferred according to the invention are characterized in that they contain, based on their weight, from 0.001 to 10% by weight, preferably from 0.01 to 5% by weight, particularly preferably from 0.05 to 2.5% by weight and in particular from 0 , 1 to 1% by weight of (S) -2-methyl-1, 4,5,6-tetrahydro-4-pyrimidinecarboxylic acid (ectoine) and the physiologically tolerated salts of this compound and / or (S, S) -5- Hydroxy-2-methyl-1, 4,5,6-tetrahydro-4-pyrimidinecarboxylic acid (hydroxyectoine) and the physiologically acceptable salts of this compound.

To improve the elasticity and strengthen the internal structure of the hair treated with the agents according to the invention, the compositions according to the invention may contain purine and / or purine derivatives as a care substance. In particular, the combination of purine and / or purine derivatives with ubiquinones and / or plastoquinones as a care substance means that the hairs treated with appropriate agents show, inter alia, higher measured values in differential thermal analysis and improved wet and dry combabilities.

Purine (7H-imidazo [4,5-d] pyrimidine) does not occur freely in nature, but forms the main body of the purines. Purines, in turn, are a group of important compounds of widespread nature involved in human, animal, plant and microbial metabolic processes, which differ from the parent by substitution with OH, NH ₂ , SH in the 2-, 6-, and 8-positions and / or with CH ₃ in 1-, 3-, 7-position derived. For example, purine can be made out Aminoacetonitrile and formamide are produced. Purines and purine derivatives are often isolated from natural products, but are also synthetically accessible in many ways.

Preferred agents according to the invention contain purine and / or purine derivatives in narrower quantitative ranges. Here are inventively preferred cosmetic agents characterized in that they - based on their weight - 0.001 to 2.5 wt .-%, preferably 0.0025 to 1 wt .-%, particularly preferably 0.005 to 0.5 wt .-% and in particular 0.01 to 0, 1 wt .-% purine (s) and / or purine derivative (s).

Among purine, the purines and the purine derivatives, some representatives are particularly preferred according to the invention. Hair treatment compositions which are preferred according to the invention are characterized in that they contain as care substance - based on their weight - from 0.001 to 2.5% by weight, preferably from 0.0025 to 1% by weight, particularly preferably from 0.005 to 0.5% by weight and in particular from 0.01 to 0.1% by weight of purine (s) and / or purine derivative (s), preferred agents containing purine and / or purine derivative (s) of formula (Pur-I)

in which the radicals R, R ² and R ^{3 are} independently selected from -H, - OH, NH ₂ , -SH and the radicals R ⁴ , R ⁵ and R ^{6 are} independently selected from -H, -CH ₃ and -CH ₂ - CH ₃ , the following compounds being preferred:

Purine (R = R ² = R ³ = R ⁴ = R ⁵ = R ⁶ = H)

Adenine (R = NH ₂ , R ² = R ³ = R ⁴ = R ⁵ = R ⁶ = H)

Guanine (R = OH, R ² = NH ₂ , R ³ = R ⁴ = R ⁵ = R ⁶ = H)

Uric acid (R = R ² = R ³ = OH, R ⁴ = R ⁵ = R ⁶ = H)

Hypoxanthine (R = OH, R ² = R ³ = R ⁴ = R ⁵ = R ⁶ = H)

6-purethiol (R = SH, R ² = R ³ = R ⁴ = R ⁵ = R ⁶ = H)

6-thioguanine (R = SH, R ² = NH ₂ , R ³ = R ⁴ = R ⁵ = R ⁶ = H)

Xanthine (R = R ² = OH, R ³ = R ⁴ = R ⁵ = R ⁶ = H)

Caffeine (R = R ² = OH, R ³ = H, R ⁴ = R ⁵ = R ⁶ = CH ₃ )

- Theobromine (R = R ² = OH, R ³ = R ⁴ = H, R ⁵ = R ⁶ = CH ₃ )

Theophylline (R = R ² = OH, R ³ = H, R ⁴ = CH ₃ , R ⁵ = CH ₃ , R ⁶ = H).

It is also advantageous to use purine or purine derivatives and biochinones in a certain ratio to each other. Here, agents according to the invention are preferred in which the weight ratio of purine (derivative (s)) and biochinone (s) is 10: 1 to 1: 100, preferably 5: 1 to 1:50, particularly preferably 2: 1 to 1:20 and in particular 1: 1 to 1:10. As already mentioned, caffeine is a particularly preferred purine derivative, and coenzyme Q10 is a particularly preferred biochinone. Particularly preferred agents according to the invention are therefore characterized in that they contain, based on their weight, from 0.001 to 2.5% by weight, preferably from 0.0025 to 1% by weight, particularly preferably from 0.005 to 0.5% by weight and in particular 0.01 to 0.1 wt .-% caffeine and 0.0002 to 4 wt .-%, preferably 0.0005 to 3 wt .-%, particularly preferably 0.001 to 2 wt .-%, more preferably 0.0015 to 1 and in particular 0.002 to 0.5 wt .-% coenzyme Q10 included.

As a conditioner, the compositions of the invention may also contain flavonoids. The flavonoids are a group of water-soluble plant dyes and play an important role in the metabolism of many plants. They belong together with the phenolic acids to the polyphenols. There are well over 6500 different flavonoids known, which can be divided into flavonols, flavones, flavanones, isoflavonoids and anthocyanins.

According to the invention flavonoids from all six groups can be used, with certain representatives from the individual groups are preferred as a care substance because of their particularly intense action. Preferred flavonols are quercetin, rutin, kaempferol, myricetin, isorhamnetin, preferred flavanols are catechin, gallocatechin, epicatechin, epigallocatechin gallate, theaflavin, thearubigin, preferred flavones are luteolin, apigenin, morin, preferred flavanones are hesperetin, naringenin, eriodictyol, preferred isoflavonoids are genistein , Daidzein, and preferred anthocyanidins (anthocyanins) are cyanidin, delphinidin, malvidin, pelargonidin, peonidin, petunidin.

According to the invention particularly preferred hair treatment compositions are characterized in that they - based on their weight - 0.001 to 2.5 wt .-%, preferably 0.0025 to 1 wt .-%, particularly preferably 0.005 to 0.5 wt .-% and in particular 0.01 to 0, 1 wt .-% flavonoids, especially flavonols, more preferably 3,3 ', 4', 5,7-Pentahydroxyflavon (quercetin) and / or 3,3 ', 4', 5,7-Pentahydroxyflavon -3-0-rutinoside (rutin), included.

Preference is also the use of bisabolol and / or bisabololoxides as a care substance in the inventive compositions. Here, hair treatment compositions according to the invention are preferred which additionally contain 0.001 to 5 wt .-%, preferably 0.01 to 4 wt .-%, particularly preferably 0.02 to 2.5 wt .-% and in particular 0.1 to 1, 5 wt % Bisabolol and / or oxides of bisabolol, preferably (-) - alpha-bisabolol.

Creatine is also suitable as a care substance according to the invention. Creatine (3-methylguanidinoacetic acid) is an organic acid that helps to supply muscles with energy in vertebrates. Creatine is synthesized in the kidney, liver and pancreas. It is formally derived from the amino acids glycine and arginine and is 95% present in skeletal muscle. Particularly preferred hair treatment compositions according to the invention contain - based on their weight - 0.01 to 15 wt .-%, preferably 0.025 to 12.5 wt .-%, particularly preferably 0.05 to 10 wt .-%, more preferably 0, 1 bis 7.5 wt .-% and in particular 0.5 to 5 wt .-% / V-methyl guanidino-acetic acid (creatine). The compositions according to the invention may contain, in addition to the ingredients mentioned above and optional further ingredients, other substances which prevent, alleviate or cure hair loss. In particular, a content of hair root stabilizing agents is advantageous. These substances are described below:

Propecia (Finasteride) is currently the only preparation that is approved worldwide and has been proven in many studies to be effective and tolerable. Propecia causes less DHT to form from testosterone.

Minoxidil is probably the oldest proven hair restorer with or without supplemental additives. For the treatment of hair loss, it may only be used for external application. There are hair lotions containing 2% -5% minoxidil, as well as gels with up to 15% minoxidil. The effectiveness increases with the dosage, in hair waters Minoxidil is only up to 5% share soluble. In many countries, hair tonic with up to 2% minoxidil content is available without prescription.

To combat the hormonal influences on the hair follicles spironolactone in the form of hair tonic and in combination with minoxidil can be used for external application. Spironolactone acts as an androgen receptor blocker, ie. the binding of DHT to the hair follicles is prevented.

In summary, hair treatment compositions according to the invention are preferred which additionally contain, based on their weight, from 0.001 to 5% by weight of hair root stabilizing substances, in particular minoxidil and / or finasteride and / or ketoconazole.

In addition to the care agents, the agents according to the invention may contain further care substances. Their presence is not absolutely necessary for achieving the effects according to the invention, but further effects, such as a pleasant touch or a pleasant application feel, can result from the use of these care substances.

As a further ingredient, the agents according to the invention may with particular preference contain one or more amino acids. Particularly preferred amino acids which can be used according to the invention are from the group of glycine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, tryptophan, proline, aspartic acid, glutamic acid, asparagine, glutamine, serine, threonine, cysteine, methionine, lysine, arginine, histidine, β Alanine, 4-aminobutyric acid (GABA), betaine, L-cystine (L-Cyss), L-carnitine, L-citrulline, L-theanine, 3 ', 4'-dihydroxy-L-phenylalanine (L-dopa), 5'-hydroxy-L-tryptophan, L-homocysteine, S-methyl-L-methionine, S-allyl-L-cysteine-sulfoxide (L-alliin), L-trans-4-hydroxyproline, L-5-oxoproline ( L-pyroglutamic acid), L-phosphoserine, creatine, 3-methyl-L-histidine, L-ornithine, whereby both the individual amino acids and mixtures can be used.

Preferred agents according to the invention contain one or more amino acids in narrower quantitative ranges. Here are preferred according to the invention hair treatment agent characterized in that it as a care substance - based on their weight - 0.01 to 5 wt .-%, preferably 0.02 to 2.5 wt .-%, particularly preferably 0.05 to 1, 5 wt .-%, further preferably 0.075 to 1 wt .-% and in particular 0.1 to 0.25 wt .-% amino acid (s), preferably from the group glycine and / or alanine and / or valine and / or lysine and / or leucine and / or Threonine included.

As a further component, the agents according to the invention may contain at least one carbohydrate from the group of monosaccharides, disaccharides and / or oligosaccharides. Here are preferred hair treatment compositions according to the invention characterized in that they are used as care substance - based on their weight - 0.01 to 5 wt .-%, preferably 0.05 to 4.5 wt .-%, particularly preferably 0.1 to 4 wt. -%, more preferably 0.5 to 3.5 wt .-% and in particular 0.75 to 2.5 wt .-% carbohydrate (s) selected from monosaccharides, disaccharides and / or oligosaccharides containing preferred carbohydrates are selected out

Monosaccharides, in particular D-ribose and / or D-xylose and / or L-arabinose and / or D-glucose and / or D-mannose and / or D-galactose and / or D-fructose and / or sorbose and / or L. Fucose and / or L-rhamnose

Disaccharides, in particular sucrose and / or maltose and / or lactose and / or trehalose and / or cellobiose and / or gentiobiose and / or isomaltose.

Particularly preferred agents according to the invention contain based on their weight

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of glucose monohydrate,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of sucrose,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of fructose.

As already mentioned, preferred agents according to the invention contain (a) amino acid (s).

Particularly preferred amino acids which can be used according to the invention are from the group glycine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, tryptophan, proline, aspartic acid, glutamic acid, asparagine, glutamine, serine, threonine, cysteine, methionine, lysine, arginine, histidine, β Alanine, 4-aminobutyric acid (GABA), betaine, L-cystine (L-Cyss), L-carnitine, L-citrulline, L-theanine, 3 ', 4'-dihydroxy-L-phenylalanine (L-dopa), 5'-hydroxy-L-tryptophan, L-homocysteine, S-methyl-L-methionine, S-allyl-L-cysteine-sulfoxide (L-alliin), L-frans-4-hydroxyproline, L-5-oxoproline ( L-pyroglutamic acid), L-phosphoserine, creatine, 3-methyl-L-histidine, L-ornithine, whereby both the individual amino acids and mixtures can be used.

Preferred agents according to the invention contain one or more amino acids in narrower quantitative ranges. Here, preferred cosmetic compositions according to the invention are characterized in that they additionally contain from 0.05 to 5% by weight, preferably from 0.1 to 2.5% by weight, more preferably from 0 to 15% by weight and in particular from 0 to 15% by weight , 2 to 0.5 wt .-% amino acid (s), preferably (one) amino acid (s) from the group glycine and / or alanine and / or valine and / or lysine and / or leucine and / or threonine.

0.005 to 0.015 wt .-% caffeine and 0.75 to 1, 5 wt .-% glucose monohydrate and

0.1 to 0.25% by weight of glycine, 0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of sucrose and 0.1 to 0.25% by weight of glycine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of fructose and 0.1 to 0.25% by weight of glycine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of glucose monohydrate and 0.1 to 0.25% by weight of alanine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of sucrose and 0.1 to 0.25% by weight of alanine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of fructose and 0.1 to 0.25% by weight of alanine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of glucose monohydrate and 0.1 to 0.25% by weight of valine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of sucrose and 0.1 to 0.25% by weight of valine,

0.005 to 0.015% by weight of caffeine and 0.75 to 1.5% by weight of fructose and 0.1 to 0.25% by weight of valine.

A particularly preferred group of ingredients are the silicones.

Preferred agents according to the invention are characterized in that they contain at least one silicone.

Particularly preferred compositions according to the invention comprise the silicone (s) preferably in amounts of from 0.1 to 10% by weight, preferably from 0.25 to 7% by weight and in particular from 0.5 to 5% by weight. , in each case based on the total mean.

Preferred silicones are described below.

Particularly preferred agents according to the invention are characterized in that they contain at least one silicone of the formula Si-I

(CH ₃ ) ₃ Si - [0-Si (CH ₃ ) 2] x -O-Si (CH ₃ ) 3 (Si-I),

in which x is a number from 0 to 100, preferably from 0 to 50, more preferably from 0 to 20 and in particular 0 to 10.

These silicones are called DIMETHICONE according to the INCI nomenclature. In the context of the present invention, the following compounds are preferably those compounds of the formula Si-I: (CH ₃ ) ₃ Si-O-Si (CH ₃ ) 3, (CH ₃ ) ₃ Si-O- (CH ₃ ) ₂ Si 0-Si (CH ₃ ) ₃ , (CH ₃ ) ₃ Si - [0- (CH ₃ ) ₂ Si] ₂ -O-Si (CH ₃ ) ₃ , (CH ₃ ) ₃ Si - [0- (CH ₃ ) ₂ Si] ₃ -0-Si (CH ₃ ) ₃ , (CH ₃ ) ₃ Si - [0- (CH ₃ ) ₂ Si] ₄ -O-Si (CH ₃ ) ₃ , (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₅ -O-Si (CH ₃ ) ₃ , (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₆ -O-Si (CH ₃ ) _3, ( CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₇ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₈ -O-Si ( CH ₃ ) _3, (CH ₃ ) ₃ Si [O- (CH ₃ ) ₂ Si] ₉ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [O- (CH ₃ ) ₂ Si] ₁₀ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] i i-0-Si (CH ₃ ) 3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₁₂ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si - [0- (CH ₃ ) ₂ Si] ₁₃ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₁₄ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₁₅ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₁₆ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₁₇ -O -Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₁₈ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si - [0- (CH ₃ ) ₂ Si] ₁₉ -O-Si (CH ₃ ) _3, (CH ₃ ) ₃ Si [O- (CH ₃ ) ₂ Si] ₂₀ -O-Si (CH ₃ ) ₃ , where (CH ₃ ) ₃ Si-O-Si (CH ₃ ) ₃ , (CH ₃ ) ₃ Si-O- (CH ₃ ) ₂ Si-O-Si (CH ₃ ) 3 and / or (CH ₃ ) ₃ Si [0- (CH ₃ ) ₂ Si] ₂ -O-Si (CH ₃ ) ₃ are particularly preferred.

Of course, mixtures of o.g. Silicones may be included in the compositions of the invention.

Preferred silicones which can be used according to the invention have viscosities of 0.2 to 2 mm ² s ^-1 at 20 ° C., silicones having viscosities of 0.5 to 1 mm ² s ^{-1 being} particularly preferred.

Particularly preferred agents according to the invention contain one or more amino-functional silicones. Such silicones may e.g. through the formula

M (R _a Q _b SiO ₍ 4- _a - _b ) / 2 ₎ x (R _c SiO (4- _c ) / 2 _{) y} M

wherein R in the above formula is a hydrocarbon or a hydrocarbon radical having 1 to about 6 carbon atoms, Q is a polar radical of the general formula -R HZ, wherein R is a divalent linking group attached to hydrogen and the radical Z. Z is an organic, amino-functional radical containing at least one amino-functional group; "a" assumes values in the range of about 0 to about 2, "b" assumes values in the range of about 1 to about 3, "a" + "b" is less than or equal to 3, and "c" is a number in the range from about 1 to about 3, and x is a number ranging from 1 to about 2,000, preferably from about 3 to about 50, and most preferably from about 3 to about 25, and y is a number ranging from about 20 to about 10,000 , preferably from about 125 to about 10,000, and most preferably from about 150 to about 1,000, and M is a suitable silicone end group as known in the art, preferably trimethylsiloxy. Non-limiting examples of the groups represented by R include alkyl groups such as methyl, ethyl, propyl, isopropyl, isopropyl, butyl, isobutyl, amyl, isoamyl, hexyl, isohexyl and the like; Alkenyl radicals such as vinyl, halovinyl, alkylvinyl, allyl, haloallyl, alkylallyl; Cycloalkyl radicals such as cyclobutyl, cyclopentyl, cyclohexyl and the like; Phenyl radicals, benzyl radicals, halohydrocarbon radicals such as 3-chloropropyl, 4-bromobutyl, 3,3,3-trifluoropropyl, chlorocyclohexyl, bromophenyl, chlorophenyl and the like, and sulfur containing radicals such as mercaptoethyl, mercaptopropyl, mercaptohexyl, mercaptophenyl and the like; preferably R is an alkyl radical containing from 1 to about 6 carbon atoms, and most preferably R is methyl. Examples of R include methylene, ethylene, propylene, hexamethylene, decamethylene, - CH ₂ CH (CH ₃ ) CH ₂ -, phenylene, naphthylene, -CH ₂ CH ₂ SCH ₂ CH ₂ -, -CH ₂ CH ₂ OCH ₂ -, -OCH ₂ CH ₂ -, - OCH ₂ CH ₂ CH ₂ -, -CH ₂ CH (CH ₃ ) C (O) ₂ -, - (CH ₂ ) ₃ CC (O) ₂ CH ₂ -, -C ₆ H ₄ C ₆ H ₄ -, -C ₆ H ₄ CH ₂ C ₆ H ₄ -; and - (CH ₂ ) ₃ C (O) SCH ₂ CH ₂ -.

Z is an organic, amino-functional radical containing at least one functional amino group. A possible formula for Z is NH (CH ₂ ) _Z NH ₂ , wherein z is 1 or more. Another possible formula for Z is -NH (CH ₂ ) _Z (CH ₂ ) _ZZ NH, wherein both z and zz are independently 1 or more, which structure includes diamino ring structures, such as piperazinyl. Z is most preferably a -NHCH ₂ CH ₂ NH ₂ radical. Another possible formula for Z is - N (CH ₂ ) z (CH ₂ ) zzNX ₂ or -NX ₂ , wherein each X of X _{2 is} independently selected from the group consisting of hydrogen and alkyl groups of 1 to 12 carbon atoms, and zz is 0.

Q is most preferably a polar, amine functional group of the formula -CH ₂ CH ₂ CH ₂ NHCH ₂ CH ₂ NH ₂ . In the formulas, "a" assumes values in the range of about 0 to about 2, "b" assumes values in the range of about 2 to about 3, "a" + "b" is less than or equal to 3, and "c "is a number in the range of about 1 to about 3. The molar ratio of the R _a Q _b SiO ( _4. _a - _b ) / 2 units to the R _c SiO ( ₄ -c) / 2 units is in the range from about 1: 2 to 1:65, preferably from about 1: 5 to about 1:65, and most preferably from about 1:15 to about 1:20. When one or more silicones of the above formula are used, then the various variables can be used Substituents in the above formula may be different for the various silicone components present in the silicone blend.

Preferred agents according to the invention are characterized in that they contain an amino-functional silicone of the formula (Si-II)

R _'a G 3-a -Si (OSiG ₂₎ n (OSiG _b R'2- _b) _m -0-SiG3-a-R'a (Si-II),

contain, in which means:

G is -H, a phenyl group, -OH, -O-CH ₃ , -CH ₃ , -O-CH ₂ CH ₃ , -CH ₂ CH ₃ , -O-

CH ₂ CH ₂ CH ₃ , CH ₂ CH ₂ CH ₃ , -O-CH (CH ₃ ) ₂ , -CH (CH ₃ ) ₂ , -O-CH ₂ CH ₂ CH ₂ CH ₃ , CH ₂ CH ₂ CH ₂ CH ₃ , -O-CH ₂ CH (CH ₃ ) ₂ , -CH ₂ CH (CH ₃ ) ₂ , -0-CH (CH ₃₎ CH ₂ CH _3, - CH (CH ₃₎ CH ₂ CH _3, -0-C (CH ₃₎ _3, -C (CH ₃₎ _3;

a is a number between 0 and 3, in particular 0;

b is a number between 0 and 1, in particular 1,

m and n are numbers whose sum (m + n) is between 1 and 2000, preferably between 50 and 150, where n is preferably values from 0 to 1999 and in particular from 49 to 149 and m preferably values from 1 to 2000, in particular from 1 to 10,

- R ^' is a monovalent radical selected from

o -QN (R ") - CH ₂ -CH ₂ -N (R") ₂

o -QN (R ") ₂

o -QN ⁺ (R ") ₃ A ^"

o -QN ⁺ H (R ") ₂ A ^"

o -QN ⁺ H ₂ (R ") A ^"

o -QN (R ") - CH ₂ -CH ₂ -N ⁺ R" H ₂ A ^" ,

each Q is a chemical bond, -CH ₂ -, -CH ₂ -CH ₂ -, -CH2CH2CH2-, -C (CH ₃₎ ₂ -, -CH2CH2CH2CH2-, -CH ₂ C (CH ₃₎ ₂ -, - CH (CH ₃ ) CH ₂ CH ₂ -,

R "is identical or different radicals from the group -H, -phenyl, -benzyl, -CH ₂ - CH (CH ₃ ) Ph, the Ci. ₂₀ -alkyl radicals, preferably -CH ₃ , -CH ₂ CH ₃ , -CH ₂ CH ₂ Cl-I ₃ , - CH (CH ₃ ) ₂ , -CH ₂ CH ₂ CH ₂ H ₃ , -CH ₂ CH (CH ₃ ) ₂ , -CH (CH ₃ ) CH ₂ CH ₃ , -C ( CH ₃ ) ₃ , and A represents an anion, which is preferably selected from chloride, bromide, iodide or methosulfate. Particularly preferred agents according to the invention are characterized in that they contain at least one amino-functional silicone of the formula (Si-IIa)

(CH ₃ ) ₃ Si [0-Si (CH ₃ ) ₂ ] _n [OSi (CH ₃ )] _m -OSi (CH ₃ ) ₃ (Si-Ila),

I

CH ₂ CH (CH 3) CH ₂ NH (CH ₂ ) ₂ NH ₂

in which m and n are numbers whose sum (m + n) is between 1 and 2000, preferably between 50 and 150, where n preferably values of 0 to 1999 and in particular of 49 to 149 and m preferably values of 1 to 2000 , in particular from 1 to 10 assumes.

These silicones are referred to as trimethylsilylamodimethicones according to the INCI declaration. Particular preference is also given to compositions according to the invention which are an amino-functional silicone of the formula (Si-IIb)

R- [Si (CH ₃ ) ₂ -O] _n ₁ [Si (R) -O] _m - [Si (CH ₃ ) ₂ ] n 2 -R (Si-Ilb),

I

in which R is -OH, -O-CH ₃ or a -CH ₃ group and m, n1 and n2 are numbers whose sum (m + n1 + n2) is between 1 and 2,000, preferably between 50 and 150 , where the sum (n1 + n2) preferably assumes values from 0 to 1999 and in particular from 49 to 149 and m preferably values from 1 to 2000, in particular from 1 to 10.

These silicones are referred to as amodimethicones according to the INCI declaration.

Regardless of which amino-functional silicones are used, agents according to the invention which contain an amino-functional silicone whose amine number is above 0.25 meq / g, preferably above 0.3 meq / g and in particular above 0.4 meq / g, are preferred , The amine number stands for the milliequivalents of amine per gram of the amino-functional silicone. It can be determined by titration and also expressed in mg KOH / g.

Agents preferred according to the invention are characterized in that, based on their weight, they contain 0.01 to 10% by weight, preferably 0.1 to 8% by weight, particularly preferably 0.25 to 7.5% by weight and in particular 0, 5 to 5 wt.% Amino-functional silicone (s) included.

The INCI CYCLOMETHICONE designated cyclic dimethicones are inventively used with preference. Here, agents according to the invention are preferred which contain at least one silicone of the formula Si-III

iO-SiiCH ^ ₂ L- (Si-III) in which x is a number from 3 to 200, preferably from 3 to 10, more preferably from 30 to 7 and especially 3, 4, 5 or 6, stands.

The silicones described above have a backbone composed of -Si-O-Si units. Of course, these Si-O-Si units may also be interrupted by carbon chains. Appropriate molecules are accessible by chain extension reactions and are preferably used in the form of silicone-in-water emulsions. Agents which are likewise preferred according to the invention are characterized in that they contain at least one silicone of the formula Si-IV

R ₃ Si [0-SiR ₂ ] _x - (CH ₂ ) _n - [0-SiR ₂ ] _y -O-SiR ₃ (Si-IV),

included, in which R stands for identical or different radicals from the group -H, - phenyl, -benzyl, -CH ₂ -CH (CH ₃₎ Ph, the CI_ ₂₀ -alkyl, preferably -CH _3, -CH ₂ CH _3, -CH ₂ CH ₂ CH ₃ , -CH (CH ₃ ) ₂ , -CH ₂ CH ₂ CH ₂ H ₃ , -CH ₂ CH (CH ₃ ) ₂ , -CH (CH ₃ ) CH ₂ CH ₃ , -C ( CH ₃ ) ₃ , x and y are a number from 0 to 200, preferably from 0 to 10, more preferably from 0 to 7 and in particular 0, 1, 2, 3, 4, 5 or 6, and n is a number from 0 to 10, preferably from 1 to 8 and in particular from 2, 3, 4, 5, 6.

The silicones are preferably water-soluble. Agents preferred according to the invention are characterized in that they contain at least one water-soluble silicone.

For aesthetic reasons, "clear" products are often preferred by consumers, hair treatment agents which are preferred according to the invention are therefore characterized by being transparent or translucent.

In the context of the present invention, transparent or translucent is understood as meaning a composition which has an NTU value of less than 100. The NTU value (Nephelometrie Turbidity Unit, NTU) is a unit used in water treatment for turbidity measurements in liquids. It is the unit of turbidity measured with a calibrated nephelometer.

Furthermore, in a preferred embodiment of the invention, an agent according to the invention may also contain UV filters (I). The UV filters to be used according to the invention are not subject to any general restrictions with regard to their structure and their physical properties. On the contrary, all UV filters which can be used in the cosmetics sector and whose absorption maximum lies in the UVA (315-400 nm), in the UVB (280-315 nm) or in the UVC (<280 nm) range are suitable. UV filters with an absorption maximum in the UVB range, in particular in the range from about 280 to about 300 nm, are particularly preferred.

The UV filters (I) are contained in the compositions according to the invention usually in amounts of 0.1-5 wt .-%, based on the total agent. Levels of 0.4-2.5 wt .-% are preferred.

The compositions of the invention may further contain a 2-pyrrolidinone-5-carboxylic acid and its derivatives (J). Preference is given to the sodium, potassium, calcium, magnesium or ammonium salts in which the ammonium ion carries, in addition to hydrogen, one to three C 1 to C ₄ alkyl groups. The sodium salt is most preferred. The amounts used in the compositions according to the invention are preferably from 0.05 to 10% by weight, based on the total agent, more preferably 0, 1 to 5, and in particular 0, 1 to 3 wt.%.

In addition, it may prove advantageous if the compositions according to the invention contain penetration aids and / or swelling agents (M). These include, for example, urea and urea derivatives, guanidine and its derivatives, arginine and its derivatives, water glass, imidazole and its derivatives, histidine and its derivatives, benzyl alcohol, glycerol, glycol and glycol ethers, propylene glycol and propylene glycol, for example Propylene glycol monoethyl ether, carbonates, bicarbonates, diols and triols, and in particular 1, 2-diols and 1, 3-diols such as 1, 2-propanediol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 2-dodecanediol, 1 , 3-propanediol, 1, 6-hexanediol, 1, 5-pentanediol, 1, 4-butanediol.

Advantageously in the context of the invention, short-chain carboxylic acids (N) may additionally support the active substance complex (A). Short-chain carboxylic acids and their derivatives in the context of the invention are understood to mean carboxylic acids which may be saturated or unsaturated and / or straight-chain or branched or cyclic and / or aromatic and / or heterocyclic and have a molecular weight of less than 750. For the purposes of the invention, preference may be given to saturated or unsaturated straight-chain or branched carboxylic acids having a chain length of from 1 to 16 C atoms in the chain, very particular preference being given to those having a chain length of from 1 to 12 C atoms in the chain.

The short-chain carboxylic acids according to the invention may have one, two, three or more carboxy groups. Preferred within the meaning of the invention are carboxylic acids having a plurality of carboxy groups, in particular di- and tricarboxylic acids. The carboxy groups may be wholly or partly present as esters, acid anhydride, lactone, amide, imidic acid, lactam, lactim, dicarboximide, carbohydrazide, hydrazone, hydroxam, hydroxime, amidine, amidoxime, nitrile, phosphonic or phosphate ester. The carboxylic acids used according to the invention may of course be substituted along the carbon chain or the ring skeleton. The substituents of the carboxylic acids used according to the invention include, for example, C 1 -C 8 -alkyl, C 2 -C 8 -alkenyl, aryl, aralkyl and aralkenyl, hydroxymethyl, C 2 -C 8 -hydroxyalkyl, C 2 -C 8 -hydroxyalkenyl , Aminomethyl, C 2 -C 8 -aminoalkyl, cyano, formyl, oxo, thioxo, hydroxy, mercapto, amino, carboxy or imino groups. Preferred substituents are C 1 -C 8 alkyl, hydroxymethyl, hydroxy, amino and carboxy groups. Particularly preferred are substituents in position. Very particularly preferred substituents are hydroxyl, alkoxy and amino groups, where the amino function may optionally be further substituted by alkyl, aryl, aralkyl and / or alkenyl radicals. Furthermore, preferred carboxylic acid derivatives are the phosphonic and phosphate esters.

In a further preferred embodiment, the agents according to the invention may contain emulsifiers (F). Emulsifiers effect at the phase interface the formation of water- or oil-stable adsorption layers, which protect the dispersed droplets against coalescence and thus stabilize the emulsion. Emulsifiers are therefore constructed like surfactants from a hydrophobic and a hydrophilic part of the molecule. Hydrophilic emulsifiers preferably form O / W emulsions and hydrophobic emulsifiers preferably form W / O emulsions. An emulsion is to be understood as meaning a droplet-like distribution (dispersion) of a liquid in another liquid under the expense of energy in order to create stabilizing phase interfaces by means of surfactants. The selection of these emulsifying surfactants or emulsifiers depends on the substances to be dispersed and the respective outer phase and the fineness of the emulsion. Emulsifiers which can be used according to the invention are, for example Addition products of 4 to 30 moles of ethylene oxide and / or 0 to 5 moles of propylene oxide to linear fatty alcohols having 8 to 22 carbon atoms, to fatty acids having 12 to 22 carbon atoms and to alkylphenols having 8 to 15 carbon atoms in the alkyl group,

C ₁₂ -C ₂ fatty acid mono- and diesters of addition products of from 1 to 30 moles of ethylene oxide onto polyols having from 3 to 6 carbon atoms, in particular to glycerol,

Ethylene oxide and polyglycerol addition products to methyl glucoside fatty acid esters, fatty acid alkanolamides and fatty acid glucamides,

C ₈ -C ₂ 2-alkylmono- and -oligoglycosides and their ethoxylated analogues, with degrees of oligomerization of from 1, 1 to 5, in particular 1, 2 to 2.0, and glucose as sugar component being preferred,

Glucosides mixtures of alkyl (oligo) and fatty alcohols, for example, the commercially available product ^® Montanov 68,

Addition products of from 5 to 60 mol of ethylene oxide onto castor oil and hydrogenated castor oil, partial esters of polyols having 3-6 carbon atoms with saturated fatty acids having 8 to 22 carbon atoms,

Sterols. Sterols are understood to mean a group of steroids which carry a hydroxyl group on C-atom 3 of the steroid skeleton and are isolated both from animal tissue (zoosterines) and from vegetable fats (phytosterols). Examples of zoosterols are cholesterol and lanosterol. Examples of suitable phytosterols are ergosterol, stigmasterol and sitosterol. Mushrooms and yeasts are also used to isolate sterols, the so-called mycosterols.

Phospholipids. Of these, especially the glucose phospholipids, e.g. as lecithins or phosphatidylcholines from e.g. Egg yolk or plant seeds (e.g., soybeans) are understood.

Fatty acid esters of sugars and sugar alcohols, such as sorbitol,

Polyglycerols and polyglycerol derivatives such as polyglycerol poly-12-hydroxystearate (commercial product Dehymuls ^® PGPH),

Linear and branched fatty acids with 8 to 30 C atoms and their Na, K, ammonium, Ca, Mg and Zn salts.

The agents according to the invention preferably contain the emulsifiers in amounts of 0.1-25% by weight, in particular 0.5-15% by weight, based on the total agent.

The compositions according to the invention may preferably contain at least one nonionic emulsifier having an HLB value of 8 to 18. Nonionic emulsifiers having an HLB value of 10 to 15 may be particularly preferred according to the invention.

It has furthermore proven to be advantageous if, in addition to the polymer (s) from the group of cationic and / or amphoteric polymers, further polymers (G) are contained in the agents according to the invention. In a preferred embodiment, the inventive agents therefore added more polymers, both anionic and nonionic polymers have been found to be effective.

The anionic polymers (G2) are anionic polymers which have carboxylate and / or sulfonate groups. Examples of anionic monomers from which such polymers may consist are acrylic acid, methacrylic acid, crotonic acid, maleic anhydride and 2-acrylamido-2-methylpropanesulfonic acid. The acidic groups may be wholly or partly present as sodium, potassium, ammonium, mono- or triethanolammonium salt. Preferred monomers are 2-acrylamido-2-methylpropanesulfonic acid and acrylic acid.

Anionic polymers which contain 2-acrylamido-2-methylpropanesulfonic acid as the sole or co-monomer can be found to be particularly effective, it being possible for all or some of the sulfonic acid group to be present as sodium, potassium, ammonium, mono- or triethanolammonium salt ,

More preferably, the homopolymer of 2-acrylamido-2-methyl propane sulfonic acid, which is commercially available, for example under the name Rheothik ^® 1 1-80 is.

Within this embodiment, it may be preferable to use copolymers of at least one anionic monomer and at least one nonionic monomer. With regard to the anionic monomers, reference is made to the substances listed above. Preferred nonionic monomers are acrylamide, methacrylamide, acrylic esters, methacrylic esters, vinylpyrrolidone, vinyl ethers and vinyl esters.

Preferred anionic copolymers are acrylic acid-acrylamide copolymers and in particular polyacrylamide copolymers with sulfonic acid-containing monomers. A particularly preferred anionic copolymer consists of 70 to 55 mol% of acrylamide and 30 to 45 mol% of 2-acrylamido-2-methylpropanesulfonic acid, wherein the sulfonic acid group is wholly or partly in the form of sodium, potassium, ammonium, mono- or triethanolammonium Salt is present. This copolymer may also be crosslinked, with crosslinking agents preferably polyolefinically unsaturated compounds such as tetraallyloxyethane, allylsucrose, allylpentaerythritol and methylene-bisacrylamide are used. Such a polymer is contained in the commercial product Sepigel ^® 305 from SEPPIC. The use of this compound, which in addition to the polymer component contains a hydrocarbon mixture (Ci ₃ -Ci ₄ -lsoparaffin) and a nonionic emulsifier (laureth-7), has proved to be particularly advantageous in the context of the teaching of the invention. Also sold under the name Simulgel ^® 600 as a compound with isohexadecane and polysorbate-80 Natriumacryloyldimethyltaurat copolymers have proved to be particularly effective according to the invention.

Likewise preferred anionic homopolymers are uncrosslinked and crosslinked polyacrylic acids. Allyl ethers of pentaerythritol, sucrose and propylene may be preferred crosslinking agents. Such compounds are for example available under the trademark Carbopol ^® commercially. Copolymers of maleic anhydride and methyl vinyl ether, especially those with crosslinks, are also color-retaining polymers. A 1, 9-decadiene crosslinked maleic acid methyl vinyl ether copolymer is available under the name ^® Stabileze QM.

In another embodiment, the agents according to the invention may contain nonionic polymers (G4).

Suitable nonionic polymers are, for example:

Vinylpyrrolidone / vinyl ester copolymers, as sold, for example, under the trademark Luviskol ^® (BASF). Luviskol ^® VA 64 and Luviskol ^® VA 73, each vinylpyrrolidone / vinyl acetate copolymers, are also preferred nonionic polymers. Cellulose ethers such as hydroxypropyl cellulose, hydroxyethyl cellulose and hydroxypropylcellulose Methylhy-, as sold for example under the trademark Culminal® ^® and Benecel ^® (AQUALON) and Natrosol ^® grades (Hercules).

Starch and its derivatives, in particular starch, such as Structure XL ^® (National Starch), a multifunctional, salt-tolerant starch;

shellac

Polyvinylpyrrolidones, as sold for example under the name Luviskol ^® (BASF).

Siloxanes. These siloxanes can be both water-soluble and water-insoluble. Both volatile and nonvolatile siloxanes are suitable, nonvolatile siloxanes being understood as meaning those compounds whose boiling point is above 200 ° C. under normal pressure. Preferred siloxanes are polydialkylsiloxanes, such as, for example, polydimethylsiloxane, polyalkylarylsiloxanes, such as, for example, polyphenylmethylsiloxane, ethoxylated polydialkylsiloxanes and polydialkylsiloxanes which contain amine and / or hydroxyl groups.

Glycosidically substituted silicones.

It is also possible according to the invention that the preparations comprise a plurality of, in particular two, different polymers of the same charge and / or in each case an ionic and an amphoteric and / or nonionic polymer.

The other polymers (G) are contained in the agents according to the invention preferably in amounts of 0.05 to 10 wt .-%, based on the total agent. Amounts of 0, 1 to 5, in particular from 0.1 to 3 wt .-%, are particularly preferred.

Another object of the present invention is a method for the treatment of keratinic fibers, in particular human hair, in which a hair treatment agent according to the invention applied to keratinic fibers and leave there either until the next hair wash (so-called "leave-on" product) or after Exposure time of 30 to 300 seconds rinsed out (so-called rinse-off product) is.

This non-therapeutic cosmetic procedure leads to a reduction of dandruff. In other words, a method of combating dandruff, in which a hair treatment agent containing - based on its weight - a) 0.0001 to 5% by weight of E silone-poly-L-lysine of the general formula (I)

where n stands for integers between 5 and 100,

b) from 0.01 to 10% by weight of climbazole

applied to the hair and scalp and either

rinsed out after a contact time of 5 seconds to 5 minutes or left there until the next hair wash

becomes, a further object of the present invention.

With respect to preferred embodiments of the method according to the invention mutatis mutandis applies to the means of the invention.

The use of epsilon-poly-L-lysines enhances and accelerates the antidandruff effect of climbazole. A further subject of the present invention is the use of epsilon-poly-L-lysine of the general formula (I)

where n stands for integers between 5 and 100,

to increase the effect of climbazole.

Another object of the present invention is the use of mixtures

a) Pol-L-lysine of the general formula (I)

where n stands for integers between 5 and 100, and

b) climbazole

for the treatment of dandruff.

Also with regard to preferred embodiments of the uses according to the invention mutatis mutandis applies to the means of the invention. Examples:

1. hair tonic:

INCI name%

Benzophenone-4 0.05

Carbomer 0.20

Alcohol denate. 40.0

Tetrahydroxypropylethylenediamine 0.20

Menthol 0.03

Polylysine 0.02

Climbazole 0.3

Pantolactone 0.3

Perfume q.s.

Aqua ad 100

2. Hair conditioner

INCI name%

Cetearyl Alcohol 6.25

Quaternium-87 0.75

Glycol Distearate 1, 00

Shea Butter 1, 50

Nephelium Lappaceum Oil 0.50

Behenoyl PG-Trimonium Chloride 1, 50

Distearoylethylhydroxyethylmonium 0.75 Methosulfate

Polylysine 1, 0

Climbazole 0.5

Lactic Acid 2.5

Panthenol 0.5

Polyquaternium-37, propylene glycol 0.40 dicaprylate / dicaprate, PPG-1 trideceth-6

Glycerol 0.10

Dimethicone 1, 00

Perfume q.s.

Water ad 100 3. Hair shampoo

INCI name%

Sodium Laureth Sulfate 15.0

Cocamidopropyl betaine 10.0

Coco glucosides 4.0

Climbazole 0.5

Niacinamide 0.3

Polyquaternium-10 0.3

Citric acid 0.5

Laureth-2 1, 2

Sodium Chloride 1, 3

Allantoin 3.0

Polylysine 0.7

Perfume q.s.

Water ad 100

4. Hair shampoo

INCI name%

Disodium Cocoamphodiacetate 8.0

Cocamidopropyl Betaine 5.0

Coco glucosides 4.0

Climbazole 0.3

Niacinamide 0.3

Citric acid 0.5

Sodium Chloride 1, 3

Pantolactone 1, 0

Epsilon-polylysine 0.1

Sodium benzoate 0.5

Salicylic acid 0.5

Water ad 100

Claims

claims

1. hair treatment composition containing - based on its weight - a) 0.0001 to 5 wt .-% epsilon-pol-L-lysine of the general formula (I)

where n stands for integers between 5 and 100,

b) from 0.01 to 10% by weight of climbazole.

Hair treatment composition according to Claim 1, characterized in that it contains from 0.0005 to 4, preferably from 0.001 to 3, more preferably from 0.005 to 2 and in particular from 0.01 to 1% by weight of epsilon-poly-L-lysine of the general formula (I) contains.

Hair treatment composition according to one of claims 1 or 2, characterized in that it contains epsilon-poly-L-lysine of the general formula (I), in which n stands for integers from 10 to 70, preferably from 15 to 60, more preferably from 20 to 50 and in particular to the numbers 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35.

Hair treatment composition according to one of Claims 1 to 3, characterized in that it contains 0.02 to 7.5, preferably 0.03 to 5, more preferably 0.04 to 2.5 and in particular 0.05 to 0.5,% by weight. Contains% climbazole.

Hair treatment composition according to one of claims 1 to 4, characterized in that it contains a total amount of epsilon-poly-L-lysine of the general formula (I) (ingredient a)) and climbazole (ingredient b)) of 0.01 to 2 wt. -%, preferably from 0, 1 to 1, 75 wt .-%, more preferably from 0.25 to 1, 5 wt .-% and in particular from 0.5 to 1, 25 wt .-%. Hair treatment composition according to one of claims 1 to 5, characterized in that it contains at least one moisturizing active substance from the group of pantolactone, glycerol, allantoin, panthenol, isopentyldiol.

Hair treatment composition according to Claim 6, characterized in that it contains the moisturizing active substance (s) in amounts of 0.1 to 10% by weight, preferably 0.15 to 7.5% by weight, more preferably 0 , 2 to 5 wt .-% and in particular from 0.25 to 4 wt .-%.

A method for combating dandruff, characterized in that a hair treatment composition containing - based on its weight - a) 0.0001 to 5 wt .-% epsilon-poly-L-lysine of the general formula (I)

where n stands for integers between 5 and 100,

b) from 0.01 to 10% by weight of climbazole

applied to the hair and scalp and either

becomes.

Use of epsilon-poly-L-lysine of the general formula (I)

where n stands for integers between 5 and 100,

to increase the effect of climbazole.

Use of mixtures from

a) Pol-L-lysine of the general formula (I)

where n stands for integers between 5 and 100, and

b) climbazole

for the treatment of dandruff.