WO2012046251A3 - Unsolvated form of ranelic acid and process for preparation thereof - Google Patents

Unsolvated form of ranelic acid and process for preparation thereof Download PDF

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Publication number
WO2012046251A3
WO2012046251A3 PCT/IN2011/000696 IN2011000696W WO2012046251A3 WO 2012046251 A3 WO2012046251 A3 WO 2012046251A3 IN 2011000696 W IN2011000696 W IN 2011000696W WO 2012046251 A3 WO2012046251 A3 WO 2012046251A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
unsolvated form
ranelic acid
ranelic
acid
Prior art date
Application number
PCT/IN2011/000696
Other languages
French (fr)
Other versions
WO2012046251A2 (en
Inventor
Milind Gharpure
Dnyandev Rane
H M Veerabhadra Swamy
Prashant Patil
Hemant Raundal
Sanjay Kadam
Original Assignee
Glenmark Generics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Limited filed Critical Glenmark Generics Limited
Publication of WO2012046251A2 publication Critical patent/WO2012046251A2/en
Publication of WO2012046251A3 publication Critical patent/WO2012046251A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Unsolvated form of ranelic acid, a process for the preparation thereof and a process for the preparation of strontium ranelate are provided.
PCT/IN2011/000696 2010-10-08 2011-10-05 Novel form of ranelic acid WO2012046251A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2801/MUM/2010 2010-10-08
IN2801MU2010 2010-10-08

Publications (2)

Publication Number Publication Date
WO2012046251A2 WO2012046251A2 (en) 2012-04-12
WO2012046251A3 true WO2012046251A3 (en) 2012-06-07

Family

ID=45928170

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2011/000696 WO2012046251A2 (en) 2010-10-08 2011-10-05 Novel form of ranelic acid

Country Status (1)

Country Link
WO (1) WO2012046251A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128367A (en) * 1989-09-01 1992-07-07 Adir Et Compagnie Divalent metal salts of 2-[N-N-di(carboxymethyl)amino]-3-cyano-4-carboxymethylthiophene-5-carboxylic acid
WO2007020527A2 (en) * 2005-08-19 2007-02-22 Glenmark Pharmaceuticals Limited Process for the preparation of strontium ranelate
WO2009074741A2 (en) * 2007-09-26 2009-06-18 Les Laboratoires Servier Novel method for the synthesis of strontiuim ranelate and of hydrates thereof
WO2010034806A1 (en) * 2008-09-29 2010-04-01 Ratiopharm Gmbh Anhydrate and hydrate forms of strontium ranelate

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128367A (en) * 1989-09-01 1992-07-07 Adir Et Compagnie Divalent metal salts of 2-[N-N-di(carboxymethyl)amino]-3-cyano-4-carboxymethylthiophene-5-carboxylic acid
WO2007020527A2 (en) * 2005-08-19 2007-02-22 Glenmark Pharmaceuticals Limited Process for the preparation of strontium ranelate
WO2009074741A2 (en) * 2007-09-26 2009-06-18 Les Laboratoires Servier Novel method for the synthesis of strontiuim ranelate and of hydrates thereof
WO2010034806A1 (en) * 2008-09-29 2010-04-01 Ratiopharm Gmbh Anhydrate and hydrate forms of strontium ranelate

Also Published As

Publication number Publication date
WO2012046251A2 (en) 2012-04-12

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